TWAS
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Traits
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Traits
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Impedance of whole body
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chr5:59,353,199-60,936,935
Best TWAS P=5.11e-09 · Best GWAS P=2.89e-12 conditioned to 1.13e-05
59.4M
59.6M
59.8M
60M
60.2M
60.4M
60.6M
60.8M
61M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Cerebellum
GNL3LP1
0.18
0.18
enet
9
0.11
3.2e-04
-3.6
-5.8
5.1e-09
-0.59
0.29
0.17
TRUE
3
METSIM
Adipose
ERCC8
0.07
0.08
blup
317
0.08
8.9e-12
-5.0
5.6
1.8e-08
0.51
0.95
0.05
FALSE
1
CommonMind
Brain Pre-frontal Cortex
ELOVL7
0.04
0.03
blup
355
0.03
1.4e-04
-4.1
5.2
2.1e-07
0.54
0.51
0.43
FALSE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
ERCC8
0.04
0.01
blup
39
0.01
8.1e-03
3.7
5.2
2.6e-07
0.48
0.00
0.22
FALSE