Best TWAS P=5.11e-09 · Best GWAS P=2.89e-12 conditioned to 1.13e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ELOVL7 | 0.04 | 0.03 | blup | 355 | 0.03 | 1.4e-04 | -4.1 | 5.2 | 2.1e-07 | 0.54 | 0.51 | 0.43 | FALSE |
| 2 | GTEx | Brain Cerebellum | GNL3LP1 | 0.18 | 0.18 | enet | 9 | 0.11 | 3.2e-04 | -3.6 | -5.8 | 5.1e-09 | -0.59 | 0.29 | 0.17 | TRUE |
| 3 | METSIM | Adipose | ERCC8 | 0.07 | 0.08 | blup | 317 | 0.08 | 8.9e-12 | -5.0 | 5.6 | 1.8e-08 | 0.51 | 0.95 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | ERCC8 | 0.04 | 0.01 | blup | 39 | 0.01 | 8.1e-03 | 3.7 | 5.2 | 2.6e-07 | 0.48 | 0.00 | 0.22 | FALSE |