Best TWAS P=1.96e-12 · Best GWAS P=1.29e-17 conditioned to 6.81e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RNF180 | 0.10 | 0.08 | lasso | 5 | 0.06 | 1.8e-03 | 5.2 | -5.5 | 4.8e-08 | 0.00 | 0.05 | 0.93 | TRUE |
| 2 | METSIM | Adipose | NLN | 0.06 | 0.03 | enet | 15 | 0.03 | 6.4e-06 | -3.1 | 5.2 | 2.2e-07 | 0.17 | 0.99 | 0.00 | FALSE |
| 3 | METSIM | Adipose | SGTB | 0.03 | 0.00 | bslmm | 384 | 0.01 | 4.7e-03 | -3.0 | 7.0 | 2.0e-12 | 0.28 | 0.23 | 0.03 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NLN | 0.06 | 0.00 | blup | 101 | 0.03 | 3.8e-04 | 4.2 | 5.2 | 2.5e-07 | 0.19 | 0.01 | 0.46 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RNF180 | 0.02 | 0.02 | blup | 58 | 0.02 | 2.0e-03 | 4.9 | -5.2 | 2.1e-07 | 0.00 | 0.03 | 0.69 | FALSE |