TWAS
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Genes
Traits
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Traits
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Impedance of whole body
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chr5:62,764,129-65,866,903
Best TWAS P=1.96e-12 · Best GWAS P=1.29e-17 conditioned to 6.81e-12
63M
63.5M
64M
64.5M
65M
65.5M
66M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
METSIM
Adipose
SGTB
0.03
0.00
bslmm
384
0.01
4.7e-03
-3.0
7.0
2.0e-12
0.28
0.23
0.03
TRUE
1
GTEx
Testis
RNF180
0.10
0.08
lasso
5
0.06
1.8e-03
5.2
-5.5
4.8e-08
0.00
0.05
0.93
TRUE
5
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
RNF180
0.02
0.02
blup
58
0.02
2.0e-03
4.9
-5.2
2.1e-07
0.00
0.03
0.69
FALSE
2
METSIM
Adipose
NLN
0.06
0.03
enet
15
0.03
6.4e-06
-3.1
5.2
2.2e-07
0.17
0.99
0.00
FALSE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NLN
0.06
0.00
blup
101
0.03
3.8e-04
4.2
5.2
2.5e-07
0.19
0.01
0.46
FALSE