TWAS
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Models
Genes
Traits
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Traits
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Impedance of whole body
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chr5:87,006,055-88,875,673
Best TWAS P=8.61e-12 · Best GWAS P=7.18e-18 conditioned to 7.15e-15
87M
87.5M
88M
88.5M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
MEF2C
0.16
0.09
enet
28
0.12
5.1e-36
6.2
-6.8
8.6e-12
0.09
0.23
0.77
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
LINC00461
0.10
0.07
lasso
2
0.05
4.5e-07
-5.3
-5.3
1.1e-07
0.04
0.98
0.02
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
CTC-498M16.2
0.11
0.13
lasso
6
0.12
1.2e-14
6.2
5.8
5.1e-09
-0.06
0.29
0.71
FALSE