Best TWAS P=8.61e-12 · Best GWAS P=7.18e-18 conditioned to 7.15e-15
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | -5.3 | -5.3 | 1.1e-07 | 0.04 | 0.98 | 0.02 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | 6.2 | 5.8 | 5.1e-09 | -0.06 | 0.29 | 0.71 | FALSE |
| 3 | YFS | Blood | MEF2C | 0.16 | 0.09 | enet | 28 | 0.12 | 5.1e-36 | 6.2 | -6.8 | 8.6e-12 | 0.09 | 0.23 | 0.77 | TRUE |