Best TWAS P=7.9e-09 · Best GWAS P=4.46e-09 conditioned to 0.0198
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | PAM | 0.07 | 0.08 | lasso | 4 | 0.07 | 5.5e-06 | -5.8 | 5.8 | 7.9e-09 | -0.75 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Whole Blood | PAM | 0.20 | 0.28 | lasso | 9 | 0.27 | 1.0e-24 | -5.5 | -5.5 | 4.5e-08 | 0.94 | 0.06 | 0.94 | FALSE |
| 3 | METSIM | Adipose | PAM | 0.04 | 0.02 | lasso | 2 | 0.02 | 2.9e-04 | -5.5 | -5.2 | 2.6e-07 | 0.89 | 0.03 | 0.95 | FALSE |
| 4 | YFS | Blood | PAM | 0.64 | 0.68 | enet | 68 | 0.72 | 0.0e+00 | -5.1 | -5.6 | 2.5e-08 | 0.91 | 0.40 | 0.60 | FALSE |