[Hub]/) : Traits : Impedance of whole body :

chr5:73,626,450-75,704,085

Best TWAS P=1.4e-19 · Best GWAS P=8.72e-22 conditioned to 0.000912

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex POC5 0.17 0.16 lasso 5 0.15 5.2e-18 8.9 -9.1 1.4e-19 -0.90 0.17 0.83 TRUE
2 GTEx Adipose Subcutaneous POC5 0.08 0.07 lasso 7 0.07 3.2e-06 6.4 6.3 2.7e-10 0.56 0.96 0.00 FALSE
3 GTEx Adipose Visceral Omentum POC5 0.13 0.08 lasso 9 0.08 6.1e-05 6.0 6.2 4.4e-10 0.60 0.82 0.07 FALSE
4 GTEx Adrenal Gland GCNT4 0.13 0.02 lasso 8 0.01 1.3e-01 5.6 6.6 4.8e-11 0.49 0.06 0.83 FALSE
5 GTEx Artery Tibial GCNT4 0.08 0.07 lasso 2 0.04 3.9e-04 5.6 -5.7 1.3e-08 -0.44 0.68 0.07 FALSE
6 GTEx Brain Cerebellar Hemisphere POLK 0.27 0.20 lasso 6 0.16 8.3e-05 5.2 6.5 9.5e-11 0.64 0.35 0.14 FALSE
7 GTEx Brain Cerebellar Hemisphere POC5 0.31 0.15 enet 18 0.30 1.6e-08 6.4 7.3 2.6e-13 0.61 0.61 0.24 FALSE
8 GTEx Brain Hypothalamus CTC-366B18.4 0.26 0.12 lasso 8 0.07 9.0e-03 6.4 -6.4 1.6e-10 -0.56 0.10 0.09 FALSE
9 GTEx Cells EBV-transformed lymphocytes POC5 0.47 0.36 lasso 4 0.39 1.3e-13 6.4 6.2 4.5e-10 0.57 1.00 0.00 FALSE
10 GTEx Cells Transformed fibroblasts POLK 0.06 0.04 lasso 3 0.04 1.0e-03 6.2 -6.4 1.8e-10 -0.61 0.24 0.47 FALSE
11 GTEx Cells Transformed fibroblasts POC5 0.15 0.17 lasso 6 0.16 3.4e-12 6.0 6.0 2.7e-09 0.57 1.00 0.00 FALSE
12 GTEx Esophagus Mucosa COL4A3BP 0.09 0.06 lasso 5 0.05 4.2e-04 4.1 -5.2 2.5e-07 -0.51 0.79 0.06 FALSE
13 GTEx Esophagus Mucosa POC5 0.18 0.16 lasso 1 0.15 4.8e-10 6.0 6.0 2.7e-09 0.57 1.00 0.00 FALSE
14 GTEx Nerve Tibial POC5 0.16 0.12 lasso 5 0.10 7.6e-08 5.9 6.0 2.6e-09 0.57 0.99 0.00 FALSE
15 GTEx Pancreas POC5 0.32 0.23 lasso 3 0.21 3.5e-09 6.0 6.1 1.3e-09 0.57 1.00 0.00 FALSE
16 GTEx Spleen POLK 0.18 -0.01 lasso 16 0.03 5.1e-02 4.2 7.7 1.8e-14 0.59 0.17 0.20 FALSE
17 GTEx Spleen POC5 0.42 0.37 lasso 4 0.34 1.3e-09 6.4 6.5 1.1e-10 0.57 0.94 0.03 FALSE
18 GTEx Spleen CTC-366B18.2 0.16 0.11 lasso 3 0.14 2.2e-04 6.4 7.8 8.0e-15 0.72 0.18 0.36 FALSE
19 GTEx Testis POC5 0.27 0.13 lasso 8 0.09 8.1e-05 7.3 -6.7 2.6e-11 -0.65 0.59 0.20 FALSE
20 GTEx Testis GCNT4 0.42 0.35 enet 62 0.37 3.8e-17 5.3 6.1 1.3e-09 0.50 1.00 0.00 FALSE
21 GTEx Thyroid POC5 0.26 0.23 enet 15 0.23 1.8e-17 5.9 5.4 6.5e-08 0.49 1.00 0.00 FALSE
22 GTEx Thyroid CTC-366B18.2 0.06 0.03 lasso 9 0.02 6.2e-03 6.0 6.2 4.5e-10 0.62 0.31 0.14 FALSE
23 METSIM Adipose POC5 0.11 0.09 enet 29 0.10 7.5e-15 5.9 5.2 1.7e-07 0.48 1.00 0.00 FALSE
24 METSIM Adipose POLK 0.05 0.01 enet 16 0.03 4.3e-05 7.6 7.4 1.6e-13 0.58 0.97 0.02 FALSE
25 ROSMAP Brain Pre-frontal Cortex POLK 0.03 0.01 lasso 7 0.02 3.9e-03 6.6 7.9 3.1e-15 0.81 0.27 0.63 FALSE
26 ROSMAP Brain Pre-frontal Cortex POC5 0.05 0.00 blup 384 0.02 8.6e-04 5.9 6.7 1.6e-11 0.57 0.30 0.13 FALSE
27 ROSMAP Brain Pre-frontal Cortex ANKDD1B 0.07 0.00 bslmm 382 0.03 7.0e-05 3.0 -6.5 6.7e-11 -0.63 0.08 0.54 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma GCNT4 0.10 0.06 enet 6 0.05 8.7e-04 3.0 -5.1 3.0e-07 -0.41 0.03 0.82 FALSE
29 The Cancer Genome Atlas Brain Lower Grade Glioma POC5 0.04 0.00 enet 7 0.03 2.1e-04 8.9 -7.6 3.3e-14 -0.77 0.02 0.57 FALSE
30 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma HMGCR 0.04 0.02 enet 4 0.03 6.0e-03 6.2 6.3 4.0e-10 0.57 0.02 0.72 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma POLK 0.03 0.01 blup 53 0.01 1.6e-02 4.0 -5.7 1.4e-08 -0.57 0.32 0.43 FALSE
32 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma POC5 0.24 0.13 blup 70 0.14 1.2e-04 6.6 7.1 1.0e-12 0.73 0.05 0.80 FALSE