Best TWAS P=1.79e-14 · Best GWAS P=7.79e-15 conditioned to 0.353
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FER | 0.10 | 0.01 | enet | 34 | 0.04 | 4.6e-06 | 0.16 | -5.5 | 3.6e-08 | -0.20 | 0.22 | 0.30 | FALSE |
2 | GTEx | Artery Tibial | FER | 0.14 | 0.06 | enet | 7 | 0.05 | 7.3e-05 | -3.67 | 5.1 | 2.9e-07 | 0.68 | 0.25 | 0.74 | TRUE |
3 | GTEx | Artery Tibial | EFNA5 | 0.17 | 0.04 | lasso | 9 | 0.07 | 6.0e-06 | 6.27 | -6.6 | 3.4e-11 | -0.05 | 0.33 | 0.66 | TRUE |
4 | GTEx | Lung | LINC01023 | 0.11 | 0.02 | enet | 16 | 0.01 | 9.3e-02 | -3.79 | -7.7 | 1.8e-14 | -0.44 | 0.09 | 0.26 | TRUE |