Best TWAS P=7.66e-14 · Best GWAS P=1.04e-18 conditioned to 2.53e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | 3.8 | -5.6 | 2.6e-08 | -0.62 | 0.03 | 0.86 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | -5.1 | -5.8 | 5.2e-09 | -0.56 | 0.01 | 0.67 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | -3.5 | -5.9 | 4.5e-09 | -0.64 | 0.10 | 0.35 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | 3.8 | -5.3 | 8.9e-08 | -0.66 | 0.03 | 0.82 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | 8.3 | -7.5 | 7.7e-14 | -0.83 | 0.06 | 0.94 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | -5.1 | -5.6 | 2.2e-08 | -0.57 | 0.01 | 0.98 | FALSE |