[Hub]/) : Traits : Impedance of whole body : ← →

chr6:33,551,514-36,158,878

Best TWAS P=1.63e-22 · Best GWAS P=5.26e-22 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	-5.4	-7.7	1.2e-14	0.37	0.32	0.05	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SNRPC	0.10	0.16	lasso	4	0.15	3.6e-18	-6.0	6.0	1.5e-09	-0.12	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	UHRF1BP1	0.17	0.23	lasso	19	0.22	5.8e-27	-5.9	-5.9	3.5e-09	0.11	1.00	0.00	FALSE
4	GTEx	Adipose Subcutaneous	UHRF1BP1	0.30	0.35	enet	28	0.36	1.6e-30	-5.8	-5.8	5.6e-09	0.11	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	UHRF1BP1	0.30	0.34	lasso	3	0.34	3.0e-18	-5.7	-5.8	6.4e-09	0.11	1.00	0.00	FALSE
6	GTEx	Artery Aorta	UHRF1BP1	0.35	0.32	lasso	10	0.30	7.7e-17	-5.9	-6.3	2.9e-10	0.15	1.00	0.00	FALSE
7	GTEx	Artery Aorta	SNRPC	0.06	0.03	enet	14	0.02	1.8e-02	-7.0	5.7	1.6e-08	-0.10	0.24	0.03	FALSE
8	GTEx	Artery Coronary	UHRF1BP1	0.33	0.36	lasso	2	0.35	1.6e-12	-5.8	-5.8	5.1e-09	0.11	1.00	0.00	FALSE
9	GTEx	Artery Tibial	UHRF1BP1	0.31	0.43	lasso	11	0.43	4.0e-36	-5.8	-5.5	4.0e-08	0.10	1.00	0.00	FALSE
10	GTEx	Artery Tibial	SNRPC	0.06	0.06	lasso	4	0.05	1.3e-04	-5.9	6.3	3.5e-10	-0.12	0.97	0.00	FALSE
11	GTEx	Brain Caudate basal ganglia	UHRF1BP1	0.19	0.14	lasso	7	0.12	3.1e-04	-5.8	-5.2	2.2e-07	0.11	0.41	0.04	FALSE
12	GTEx	Brain Caudate basal ganglia	SNRPC	0.19	0.15	lasso	3	0.06	7.7e-03	-5.8	6.2	6.5e-10	-0.11	0.44	0.03	FALSE
13	GTEx	Brain Cerebellar Hemisphere	UHRF1BP1	0.22	0.16	lasso	12	0.15	1.0e-04	-5.8	-6.5	6.6e-11	0.12	0.43	0.06	FALSE
14	GTEx	Brain Frontal Cortex BA9	RPS10	0.21	0.08	lasso	3	0.06	8.6e-03	-8.0	-9.1	6.1e-20	0.75	0.06	0.57	FALSE
15	GTEx	Brain Putamen basal ganglia	UHRF1BP1	0.20	0.17	lasso	2	0.16	1.5e-04	-5.8	-5.9	4.5e-09	0.13	0.23	0.16	FALSE
16	GTEx	Breast Mammary Tissue (Male)	UHRF1BP1	0.19	0.16	enet	24	0.08	5.6e-03	-5.8	-5.8	4.9e-09	0.13	0.44	0.06	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	-6.6	-6.1	1.1e-09	0.14	0.07	0.05	TRUE
18	GTEx	Cells Transformed fibroblasts	UHRF1BP1	0.34	0.32	enet	44	0.31	2.4e-23	-5.8	-6.0	1.9e-09	0.12	1.00	0.00	FALSE
19	GTEx	Cells Transformed fibroblasts	RPS10	0.12	0.05	lasso	4	0.06	4.5e-05	-9.6	-9.8	1.6e-22	0.93	0.02	0.98	TRUE
20	GTEx	Colon Transverse	UHRF1BP1	0.42	0.28	lasso	4	0.28	1.6e-13	-5.7	-6.2	4.6e-10	0.12	1.00	0.00	FALSE
21	GTEx	Esophagus Gastroesophageal Junction	UHRF1BP1	0.47	0.38	enet	22	0.43	7.3e-17	-7.0	-6.3	2.9e-10	0.08	1.00	0.00	FALSE
22	GTEx	Esophagus Mucosa	UHRF1BP1	0.14	0.15	enet	28	0.17	1.3e-11	-5.9	-5.9	3.3e-09	0.12	1.00	0.00	FALSE
23	GTEx	Esophagus Mucosa	SNRPC	0.12	0.10	lasso	2	0.08	4.8e-06	-6.0	6.0	2.2e-09	-0.11	0.99	0.00	FALSE
24	GTEx	Esophagus Muscularis	UHRF1BP1	0.42	0.35	enet	48	0.33	1.0e-20	-5.8	-5.2	1.6e-07	0.18	1.00	0.00	FALSE
25	GTEx	Esophagus Muscularis	SNRPC	0.09	0.11	lasso	3	0.07	3.8e-05	-5.8	6.3	3.5e-10	-0.12	0.98	0.00	FALSE
26	GTEx	Esophagus Muscularis	NUDT3	0.12	0.00	lasso	7	0.02	3.2e-02	-9.6	9.1	7.6e-20	-0.85	0.02	0.85	FALSE
27	GTEx	Liver	UHRF1BP1	0.13	0.04	lasso	3	0.05	1.8e-02	-5.8	-5.9	3.5e-09	0.08	0.17	0.08	TRUE
28	GTEx	Lung	UHRF1BP1	0.17	0.20	enet	22	0.18	4.3e-14	-5.8	-5.9	4.1e-09	0.10	1.00	0.00	FALSE
29	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	-5.9	6.1	1.0e-09	-0.13	0.38	0.02	FALSE
30	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	-5.3	6.6	5.2e-11	-0.19	0.98	0.00	FALSE
31	GTEx	Nerve Tibial	UHRF1BP1	0.31	0.31	lasso	6	0.31	3.9e-22	-5.8	-5.9	3.5e-09	0.12	1.00	0.00	FALSE
32	GTEx	Nerve Tibial	SNRPC	0.12	0.10	lasso	4	0.08	1.5e-06	-5.8	5.9	3.7e-09	-0.11	1.00	0.00	FALSE
33	GTEx	Skin Not Sun Exposed Suprapubic	SNRPC	0.18	0.04	enet	37	0.03	1.0e-02	-5.9	5.7	1.0e-08	-0.18	0.23	0.11	FALSE
34	GTEx	Skin Sun Exposed Lower leg	SNRPC	0.03	0.04	lasso	2	0.03	1.9e-03	-5.8	5.9	4.7e-09	-0.11	0.58	0.02	FALSE
35	GTEx	Small Intestine Terminal Ileum	UHRF1BP1	0.20	0.03	lasso	5	0.00	3.4e-01	-5.8	-5.2	2.4e-07	0.09	0.14	0.05	FALSE
36	GTEx	Spleen	UHRF1BP1	0.34	0.21	enet	36	0.17	4.5e-05	-6.0	-7.3	3.6e-13	0.32	0.62	0.04	TRUE
37	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	-5.6	-5.8	7.7e-09	0.17	1.00	0.00	FALSE
38	GTEx	Testis	RPS10	0.17	0.11	lasso	1	0.04	5.2e-03	-8.0	-8.0	1.8e-15	0.74	0.09	0.69	FALSE
39	GTEx	Thyroid	SNRPC	0.07	0.04	lasso	6	0.05	1.6e-04	-5.8	5.7	1.2e-08	-0.11	0.83	0.01	FALSE
40	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	-5.8	-7.0	3.6e-12	0.17	0.10	0.08	FALSE
41	GTEx	Whole Blood	UHRF1BP1	0.14	0.14	lasso	7	0.14	2.9e-13	-5.8	-5.1	3.0e-07	0.13	1.00	0.00	FALSE
42	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	-4.7	-6.1	9.1e-10	0.11	0.42	0.03	TRUE
43	METSIM	Adipose	UHRF1BP1	0.16	0.31	enet	30	0.32	1.0e-49	-5.9	-5.4	8.3e-08	0.11	1.00	0.00	FALSE
44	NTR	Blood	UHRF1BP1	0.03	0.05	enet	19	0.05	7.4e-15	-5.5	-5.4	5.9e-08	0.09	1.00	0.00	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	TEAD3	0.07	0.03	bslmm	421	0.04	5.6e-06	-3.7	6.7	2.8e-11	-0.23	0.18	0.78	TRUE
46	ROSMAP	Brain Pre-frontal Cortex	UHRF1BP1	0.16	0.27	lasso	10	0.28	2.7e-36	-5.5	-5.6	2.4e-08	0.11	1.00	0.00	FALSE
47	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	-5.3	-5.5	4.2e-08	0.38	0.18	0.08	FALSE
48	ROSMAP	Brain Pre-frontal Cortex	SNRPC	0.15	0.27	lasso	4	0.27	4.0e-35	-5.9	5.8	5.4e-09	-0.11	1.00	0.00	FALSE
49	YFS	Blood	NUDT3	0.12	0.12	lasso	9	0.13	2.5e-40	-8.0	-6.7	2.8e-11	0.61	1.00	0.00	TRUE
50	YFS	Blood	SNRPC	0.02	0.03	lasso	5	0.02	3.0e-08	-7.0	7.1	1.2e-12	-0.12	1.00	0.00	TRUE
51	YFS	Blood	UHRF1BP1	0.18	0.34	enet	36	0.34	2.5e-117	-5.9	-6.3	2.6e-10	0.16	1.00	0.00	FALSE
52	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UHRF1BP1	0.03	0.04	lasso	3	0.04	1.7e-04	-5.8	-5.8	5.0e-09	0.11	0.08	0.74	FALSE
53	The Cancer Genome Atlas	Breast Invasive Carcinoma	SNRPC	0.01	0.01	blup	31	0.00	3.0e-02	-3.0	5.2	2.4e-07	-0.12	0.03	0.14	FALSE
54	The Cancer Genome Atlas	Breast Invasive Carcinoma	UHRF1BP1	0.04	0.05	lasso	3	0.04	8.4e-09	-5.8	-5.8	7.0e-09	0.11	0.65	0.35	FALSE
55	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	UHRF1BP1	0.07	0.11	lasso	3	0.07	2.6e-04	-5.7	-5.7	1.1e-08	0.11	0.22	0.72	FALSE
56	The Cancer Genome Atlas	Colon Adenocarcinoma	UHRF1BP1	0.08	0.11	lasso	12	0.10	2.3e-06	-5.9	-5.8	5.0e-09	0.11	0.41	0.58	FALSE
57	The Cancer Genome Atlas	Esophageal Carcinoma	UHRF1BP1	0.19	0.20	lasso	10	0.17	5.2e-06	-5.7	-5.8	8.8e-09	0.11	0.55	0.39	FALSE
58	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SNRPC	0.06	0.07	lasso	2	0.07	6.7e-08	-5.8	5.8	5.9e-09	-0.11	0.66	0.34	FALSE
59	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	UHRF1BP1	0.18	0.28	lasso	5	0.27	1.0e-30	-5.8	-6.0	2.7e-09	0.12	0.91	0.09	FALSE
60	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	-5.3	-5.5	4.7e-08	0.13	0.94	0.06	FALSE
61	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UHRF1BP1	0.12	0.09	blup	70	0.06	5.6e-04	-5.8	-6.5	6.9e-11	0.11	0.07	0.78	TRUE
62	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	-5.3	-5.1	3.0e-07	0.08	0.20	0.53	FALSE
63	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	UHRF1BP1	0.06	0.07	lasso	1	0.05	1.5e-04	-5.5	-5.5	4.0e-08	0.10	0.22	0.74	FALSE
64	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	UHRF1BP1	0.20	0.23	lasso	16	0.25	8.3e-11	-5.9	-5.4	8.1e-08	0.12	0.88	0.12	FALSE
65	The Cancer Genome Atlas	Prostate Adenocarcinoma	UHRF1BP1	0.10	0.20	lasso	5	0.19	1.6e-19	-5.8	-5.6	2.0e-08	0.11	0.92	0.08	FALSE
66	The Cancer Genome Atlas	Stomach Adenocarcinoma	UHRF1BP1	0.08	0.10	lasso	1	0.10	7.1e-08	-5.9	-5.9	4.3e-09	0.11	0.80	0.20	FALSE
67	The Cancer Genome Atlas	Thyroid Carcinoma	SNRPC	0.05	0.05	blup	31	0.05	2.9e-05	-5.8	5.3	9.5e-08	-0.13	0.67	0.25	FALSE
68	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SNRPC	0.09	0.11	lasso	2	0.10	8.1e-04	-5.8	5.8	5.8e-09	-0.11	0.03	0.58	FALSE