TWAS hub - LRRC4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0330	0.0180	5.2e-03	0.003	0.004	-0.002	0.004	-0.001	1.2e-01	1.0e-01	7.1e-01	8.5e-02	5.4e-01
2	GTEx	Adrenal Gland	0.2014	0.0782	9.5e-04	0.012	NA	-0.005	NA	0.054	1.1e-01	NA	5.1e-01	NA	5.2e-03
3	GTEx	Brain Cerebellar Hemisphere	0.1410	0.0680	6.9e-03	0.090	NA	0.011	NA	0.040	2.7e-03	NA	1.6e-01	NA	3.4e-02
4	GTEx	Nerve Tibial	0.0699	0.0319	8.2e-04	0.002	NA	0.010	NA	0.020	2.3e-01	NA	5.9e-02	NA	1.3e-02
5	GTEx	Thyroid	0.0830	0.0320	1.2e-04	0.073	NA	0.058	NA	0.065	2.8e-06	NA	2.9e-05	NA	1.1e-05
6	NTR	Blood	0.0226	0.0088	9.2e-05	0.019	0.017	0.012	0.018	0.017	4.7e-07	2.8e-06	7.5e-05	9.1e-07	1.8e-06
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0947	0.0384	1.6e-09	0.025	0.083	0.088	NA	0.082	7.9e-04	1.2e-09	3.9e-10	NA	1.7e-09
8	TCGA	Lung Adenocarcinoma	0.0204	0.0122	3.6e-03	0.029	0.015	0.014	NA	0.018	2.1e-04	6.5e-03	8.8e-03	NA	2.8e-03
9	TCGA	Thyroid Carcinoma	0.1450	0.0610	2.1e-10	0.086	0.116	0.103	NA	0.115	1.0e-08	2.5e-11	3.3e-10	NA	2.7e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Verbal and Numeric Reasoning (VNR)	6.9	16.6	37.9	6.2	-3.5	5.5	-5.8	-1.2	2.5	-3.4	3.5	-2.2
Worrier / anxious feelings	6.6	12.5	28.6	-4.5	5.1	-5.3	2.0	-1.3	-1.2	0.9	-5.3	1.1
Birth weight	6.6	14.2	25.5	-5.0	5.0	-3.5	4.2	0.5	-1.4	3.8	-4.9	2.8
Intelligence (Savage-Jansen 2018)	6.1	18.8	35.8	6.0	-4.5	4.5	-5.7	-1.6	3.0	-4.5	4.7	-2.6
Mouth/teeth dental problems: Bleeding gums	5.3	6.8	11.4	2.4	-3.4	3.3	-2.5	-2.0	0.5	-3.1	2.2	-2.9
Risk taking	4.9	7.1	19.9	3.8	-2.7	3.1	-2.9	1.0	0.7	-1.1	4.5	-1.1
Serious illness, injury or assault of a close relative in last 2 years	4.5	5.1	12.8	-1.4	3.6	-1.6	2.6	2.5	-0.1	2.7	-1.0	2.6
Average weekly spirits intake	4.3	5.3	14.7	-1.7	3.8	-2.9	2.9	2.2	-0.8	1.8	-0.1	2.3
Commuting to job workplace: Cycle	4.1	5.0	9.6	2.5	-2.9	2.7	-3.1	-1.5	1.6	-1.7	2.0	-1.2
Handedness (chirality/laterality): Left-handed	3.6	4.3	16.0	-2.4	1.2	-1.4	-0.1	-3.0	-1.9	-0.4	-4.0	-0.8
Schizophrenia (2014)	3.5	7.8	17.3	-0.2	-3.4	0.6	-1.7	-4.2	-1.1	-4.1	-2.3	-3.8
Birth weight of first child	3.4	6.1	12.9	-2.7	3.6	-3.1	3.1	0.5	0.0	2.1	-2.5	2.3
Mean time to correctly identify matches	3.3	6.3	17.3	0.2	-2.6	0.7	-1.3	-3.7	-0.6	-4.2	-1.3	-3.8
Reaction Time	3.1	5.9	15.2	-1.2	-1.7	-0.2	-0.7	-3.9	-1.0	-3.7	-2.4	-3.5
Major Depression (MDD)	2.9	3.5	10.3	1.9	-3.2	1.9	-1.8	-0.9	-0.2	-2.4	0.8	-1.9
Number of treatments/medications taken	2.9	5.2	14.7	-1.6	3.8	-2.1	3.0	1.9	-0.2	2.6	-0.9	2.1
Supplements: Vitamin C	2.9	3.4	7.4	-0.5	-1.5	0.5	-0.9	-2.6	-1.7	-2.6	-2.0	-2.7
Heart attack/myocardial infarction (self-reported)	2.9	3.7	9.5	-0.7	-1.4	0.7	-0.4	-3.1	-1.2	-2.5	-2.2	-2.8
Schizophrenia (2018)	2.8	5.8	12.8	-1.8	-1.7	-0.3	-0.5	-3.6	-2.3	-2.8	-2.9	-3.5
Hand grip strength (left)	2.8	7.4	18.2	-3.6	4.0	-1.7	1.2	-0.4	-3.5	1.7	-4.3	0.9
HbA1C	2.7	3.0	10.3	2.5	-1.4	0.6	-0.5	1.2	3.2	0.9	1.9	1.6
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.2	7.7	-0.8	1.2	-2.0	1.0	-1.7	-2.8	-1.9	-2.0	-1.8
Chronotype (morning person)	2.6	6.1	16.2	-4.0	3.2	-3.7	1.0	-1.2	-1.0	0.9	-3.2	0.6
Heart attack	2.6	3.3	8.3	-1.0	-1.2	0.4	-0.2	-2.9	-1.3	-2.3	-2.3	-2.5
Chest pain or discomfort	2.6	3.7	9.7	2.0	-3.1	2.3	-0.9	-1.6	1.2	-1.4	1.6	-2.3
Mother’s age at death	2.6	3.2	11.2	3.3	-1.1	2.3	-2.0	0.5	1.6	-0.4	2.0	0.3
Number of full brothers	2.5	3.2	8.7	-0.3	-1.8	1.6	-1.3	-1.8	-1.7	-2.4	0.3	-3.0
Friendships satisfaction	2.5	3.0	6.7	0.7	-2.2	1.2	-1.8	-2.6	0.6	-2.2	0.7	-2.3
Illnesses of siblings: Diabetes	2.4	3.0	9.0	-2.6	2.2	-1.4	0.4	-1.1	-1.8	0.2	-3.0	-0.1
Alcohol drinker status: Never	2.4	2.8	5.2	-1.2	-0.2	1.5	-1.1	-2.3	-1.5	-2.1	-1.9	-2.2
Depressed Affect (Nagel 2018)	2.3	4.8	14.6	-2.7	2.4	-3.8	3.0	1.0	-0.1	1.9	-0.7	1.3
Schizophrenia vs Biploar Disorder	2.3	3.1	9.1	-0.2	-2.3	0.0	-0.7	-1.7	-1.8	-2.6	0.1	-3.0
Neuroticism	2.3	5.5	16.2	-3.4	2.1	-4.0	2.7	-0.8	-1.5	1.0	-2.5	-0.3
Neuroticism score	2.3	4.7	16.1	-3.2	2.1	-4.0	2.6	0.3	-1.1	1.0	-1.6	0.3
Taking other prescription medications	2.2	3.3	9.0	-1.1	2.0	-1.5	3.0	2.2	1.0	2.1	0.3	1.9
Tinnitus: Yes, but not now, but have in the past	2.2	2.4	6.0	0.5	-2.5	0.9	-2.2	-1.6	0.2	-1.9	0.5	-1.7
Worry (Nagel 2018)	2.1	4.5	10.4	-3.2	1.8	-3.0	1.6	-1.5	-1.4	-0.2	-3.2	-0.9
Systolic Blood Pressure	2.1	10.3	19.4	-2.9	3.8	-4.4	3.2	2.6	-1.4	3.5	-2.2	3.8
Alcohol usually taken with meals	2.1	3.4	7.5	-0.1	2.4	-1.2	2.0	2.1	0.9	2.6	0.4	2.7
Medication: Ibuprofen	2.1	2.5	6.9	1.3	1.2	0.5	0.5	2.6	1.5	2.0	1.4	2.0
Commuting to job workplace: Car/motor vehicle	2.1	2.4	5.1	-2.3	1.8	-2.2	1.5	-0.3	-1.3	0.8	-1.8	0.6
Fractured/broken bones in last 5 years	2.1	2.8	6.8	1.3	0.7	-0.5	1.2	2.6	2.0	2.1	0.7	2.3
Hand grip strength (right)	2.0	5.5	16.5	-2.6	4.1	-2.1	1.3	0.4	-2.6	1.7	-3.0	1.4
Qualifications: CSEs or equivalent	2.0	2.6	6.0	-0.1	2.1	-1.4	2.4	2.1	-0.8	2.0	0.3	1.4
Medication: Atenolol	2.0	2.5	9.2	-1.9	1.2	-1.8	0.6	-1.5	-1.5	-0.3	-3.0	0.0
Hearing difficulty/problems with background noise	2.0	3.1	6.9	-1.1	-1.6	0.2	-1.0	-2.6	-1.9	-1.9	-1.6	-2.6
Qualifications: College or University degree	2.0	6.4	13.3	3.4	-2.5	0.0	-3.6	-1.9	1.2	-2.9	3.3	-1.4
Illnesses of father: None of the above (group 1)	1.9	2.3	3.6	1.2	-1.2	1.9	-1.7	1.7	1.7	0.8	1.5	1.6
Tinnitus: Yes, now most or all of the time	1.9	2.3	6.5	2.0	-1.6	2.5	-1.4	0.4	1.0	-0.2	2.0	-0.1
Medication: Paracetamol	1.9	3.0	6.5	0.7	2.0	-0.4	0.7	2.5	1.2	2.3	1.5	2.5
Bipolar Disorder or Schizophrenia	1.8	4.4	13.0	-0.3	-2.3	1.0	-1.3	-3.6	-0.5	-2.8	-2.1	-2.5
Mean Putamen Volume	1.8	2.1	5.3	-1.4	1.9	-0.9	1.0	0.3	0.8	2.3	-1.2	1.9
Impedance of leg (right)	1.8	8.6	29.5	3.7	-2.4	3.7	-1.6	3.0	0.2	-1.3	5.4	-1.2
Fed-up feelings	1.8	3.3	8.1	-2.4	1.5	-2.9	2.3	1.8	-0.3	1.6	0.0	1.6
Fluid intelligence score	1.8	3.8	9.5	3.1	-0.5	2.9	-3.0	-0.9	1.4	-1.2	1.5	-0.7
Hair/balding pattern: Pattern 3	1.8	2.6	9.7	-1.1	3.1	-1.6	1.6	-0.5	-0.4	1.2	-2.3	0.8
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	7.0	0.5	-1.2	0.3	-1.4	-2.6	-0.4	-2.5	-0.1	-1.7
Smoking status: Previous	1.8	2.7	6.3	1.6	-0.4	2.5	-2.2	-0.7	-2.0	-2.0	0.0	-1.4
Medication: Lisinopril	1.8	2.3	7.1	-0.7	1.8	-2.7	0.9	1.2	1.0	1.3	0.4	2.2
Impedance of leg (left)	1.7	8.2	27.0	3.9	-1.9	3.5	-1.6	3.3	-0.2	-1.2	5.2	-0.9
Alcohol intake frequency.	1.7	4.0	18.0	-2.8	1.0	-0.5	1.3	-2.2	-0.9	0.9	-4.2	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	6.4	0.7	-1.7	1.9	-2.5	-1.1	0.4	-0.3	1.0	-0.8
Osteoporosis (self-reported)	1.7	2.2	5.7	0.2	0.9	-2.4	-0.2	1.8	0.7	2.1	0.5	2.1
Prostate Cancer	1.6	2.3	7.3	-2.7	1.4	-1.6	2.3	-0.4	-0.8	0.9	-1.1	0.5
Sensitivity / hurt feelings	1.6	2.8	5.4	-2.2	1.9	-2.3	1.3	-0.2	-1.9	1.0	-2.2	-0.1
Ever used hormone-replacement therapy (HRT)	1.6	2.1	3.7	1.3	-1.0	1.8	-1.9	-1.6	-0.9	-1.5	0.2	-1.9
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.4	2.3	-1.7	2.0	-1.0	0.3	0.2	-1.1	1.3	-0.9
Medication: Blood pressure	1.6	2.7	5.0	-2.2	1.6	-1.6	1.8	-1.4	-1.9	-0.8	-2.2	-0.4
Knee pain experienced in last month	1.6	2.5	6.6	-1.1	2.6	-1.9	2.1	-0.6	-0.3	0.4	-2.4	0.5
Mood swings	1.6	3.0	9.0	-1.6	2.6	-3.0	2.0	1.3	0.4	1.0	-0.2	1.2
Osteoarthritis (self-reported)	1.6	2.1	5.3	-0.1	1.5	-0.7	1.6	1.6	0.7	2.2	-0.4	2.3
Neuroticism (Nagel 2018)	1.5	3.5	12.6	-2.6	1.6	-3.5	1.6	-0.9	-1.2	-0.2	-2.0	-0.7
Body Mass Index (BMI) (2010)	1.5	2.0	6.9	-1.9	1.2	-0.8	0.2	-1.7	-1.3	-0.4	-2.6	-0.8
Systolic blood pressure, automated reading	1.5	4.3	9.7	-1.8	2.4	-3.1	2.3	0.6	-1.2	2.0	-2.3	1.9
Vitamin and mineral supplements	1.5	2.0	8.6	0.1	0.4	0.5	-0.2	0.6	2.9	1.8	0.8	2.2
Severe depression (siblings)	1.5	1.7	5.8	2.4	-0.7	1.9	-2.0	0.2	-0.7	-0.4	-0.2	-0.8
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	3.1	-0.4	-1.2	1.7	-1.6	-1.4	-0.7	-1.8	-0.2	-1.7
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	4.1	-0.2	-0.6	1.4	-1.8	-1.3	-2.0	-1.4	-0.1	-1.7
Loud music exposure frequency	1.5	1.6	4.6	1.0	-1.4	1.8	-2.1	-0.6	0.4	-1.5	0.4	-0.9
Medication: Paracetamol	1.5	2.4	5.2	0.1	2.3	-1.1	1.2	1.9	1.0	2.0	0.7	2.1
Medication: Ventolin 100micrograms inhaler	1.5	1.9	4.1	1.8	0.6	0.7	-1.0	1.4	2.0	0.6	2.0	1.2
Wheeze or whistling in the chest in last year	1.5	2.7	6.5	2.0	-1.9	2.4	-1.1	0.5	1.1	-0.7	2.5	-1.2
Neck or shoulder pain in last month	1.5	2.2	8.5	-0.6	2.6	0.0	0.4	-0.1	-2.9	-0.1	-1.9	-0.8
Ever had prostate specific antigen (PSA) test	1.5	1.7	4.5	-0.6	1.4	-0.4	-1.3	-1.1	-2.1	-1.7	-1.1	-1.2
Ovarian Cancer	1.4	1.9	6.0	-1.1	2.5	-1.5	1.8	1.4	-1.0	0.5	-0.9	0.6
Frequency of depressed mood in last 2 weeks	1.4	2.0	4.1	-1.9	1.0	-1.7	2.0	0.2	-1.9	0.7	-1.4	-0.2
Diabetes (mother)	1.4	1.8	4.2	1.7	0.3	0.3	-0.1	1.6	2.0	1.5	1.4	1.4
Number of incorrect matches in round	1.4	2.3	4.4	-0.1	-2.1	1.3	-1.6	-1.8	-1.0	-1.8	-0.8	-1.8
Hair/balding pattern: Pattern 2	1.4	1.8	3.7	-0.5	-1.0	1.1	-0.8	-1.5	-1.8	-1.8	-0.5	-1.9
Illnesses of siblings	1.4	2.0	6.6	1.2	-1.4	0.8	-1.8	1.4	1.0	0.5	2.6	1.0
Mouth/teeth dental problems: Dentures	1.4	2.3	5.2	1.0	1.2	-1.0	1.3	1.3	1.9	2.2	0.0	2.3
Migraine (self-reported)	1.4	1.8	5.2	-0.5	1.2	-1.1	-0.1	2.3	0.7	1.9	0.1	2.0
Impedance of whole body	1.4	7.4	20.4	4.0	-2.4	3.3	-2.1	2.6	1.0	-1.1	4.5	-0.5
Bipolar Disorder (2018)	1.3	2.1	4.5	1.8	-1.5	1.9	-1.5	-1.3	2.1	-0.9	0.2	0.3
Fasting Glucose	1.3	1.5	3.5	1.6	-0.1	-0.6	0.2	1.9	1.6	0.3	1.8	1.2
Average weekly fortified wine intake	1.3	1.5	5.7	-2.4	0.9	-0.9	1.3	-1.1	-1.1	0.7	-1.3	0.1
High blood pressure (siblings)	1.3	1.9	4.6	-1.4	2.1	-1.7	1.7	0.4	-0.6	0.8	-1.7	0.6
Illnesses of father: Heart disease	1.3	1.8	5.4	-0.6	-0.3	-0.2	0.2	-1.7	-1.3	-2.3	-1.3	-2.1
Mineral and other dietary supplements	1.3	1.8	4.8	0.3	-0.4	-0.6	0.9	1.7	1.9	1.0	2.2	1.6
Average weekly champagne plus white wine intake	1.3	1.8	4.4	1.4	0.2	-0.2	-0.0	1.6	1.9	0.9	2.1	1.6
Supplements: Fish oil (including cod liver oil)	1.3	1.6	4.8	-0.3	0.1	0.7	-1.3	-1.2	-2.2	-1.2	-1.6	-1.5
Basal cell carcinoma (self-reported)	1.3	1.5	7.2	0.4	-0.5	2.7	-0.6	0.4	-2.0	-0.5	0.1	-1.1
Type 2 Diabetes (T2D) (2012)	1.2	1.4	3.5	0.9	-1.6	1.3	-1.9	-0.2	1.9	-0.0	0.7	0.3
Townsend deprivation index at recruitment	1.2	1.7	4.6	1.0	-2.1	1.2	0.1	0.3	0.6	-1.3	2.1	-1.2
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.8	4.7	-2.2	1.1	-1.9	1.7	-0.7	-1.1	-0.4	-1.3	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.8	5.7	-1.3	0.2	1.3	0.4	-2.4	-2.0	-1.1	-2.2	-2.3
Mouth/teeth dental problems	1.2	1.8	5.6	-2.4	1.6	-1.2	1.0	1.1	-1.4	0.8	-1.0	0.5
Headache pain in last month	1.2	2.1	6.2	-1.9	2.5	-1.4	0.6	0.7	-0.2	1.5	-1.8	1.0
Worry too long after embarrassment	1.2	2.1	4.8	-1.0	-0.8	-0.7	-0.3	-2.0	-1.5	-1.8	-1.6	-2.2
Pain type(s) experienced in last month: Hip pain	1.2	1.5	4.8	-0.1	1.8	-1.2	2.2	0.2	-0.4	0.7	-1.8	0.5
Depression (Nagel 2018)	1.1	1.6	3.8	-1.5	-0.1	-0.7	1.3	-1.1	-1.9	0.4	-2.0	-1.1
Heel T-Score	1.1	8.4	20.2	-0.3	-1.6	2.9	-3.3	-4.5	-2.5	-2.4	-2.8	-3.7
Maternal smoking around birth	1.1	1.6	5.0	0.7	-1.8	0.8	-1.4	-1.1	2.2	-1.1	0.3	-0.4
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.9	-0.2	-1.7	-0.0	-0.9	-1.2	-1.2	-1.4	-1.3	-1.2
Time employed in main current job	1.1	1.2	3.8	-1.0	0.2	-0.4	-0.1	-1.9	-1.2	-0.7	-1.8	-1.0
Happiness	1.1	1.4	4.4	0.3	-2.1	0.4	-0.7	-1.2	0.6	-1.5	1.1	-1.4
Asthma	1.1	2.1	6.2	2.4	-0.4	1.0	0.3	1.4	1.9	0.7	2.5	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.7	1.3	0.9	0.7	-0.1	1.9	1.5	1.2	1.0	1.3
Depression (self-reported)	1.1	1.4	3.4	-1.0	0.7	-0.2	1.2	1.4	1.1	1.6	0.1	1.8
Suffer from ‘nerves’	1.1	1.8	5.4	-2.3	1.0	-1.1	1.6	-0.5	-1.2	0.4	-1.9	-0.3
Family relationship satisfaction	1.1	1.4	5.5	0.1	-0.9	1.6	-0.1	-1.4	-0.5	-1.0	0.1	-2.3
Miserableness	1.1	1.9	8.4	-2.4	-0.0	-2.9	1.4	0.1	-0.9	0.8	0.1	0.2
Cholesterol lowering medication	1.1	1.6	5.1	-0.2	1.5	-2.3	0.7	-0.7	1.0	1.1	-1.5	1.1
Cardiovascular Disease	1.0	3.2	6.7	-1.2	2.6	-2.4	1.6	-0.5	0.9	2.2	-1.3	2.2
Current tobacco smoking	1.0	1.6	4.4	-1.4	-0.0	-1.1	2.1	1.7	0.4	1.5	1.0	0.8
Prospective memory result	1.0	1.3	3.6	-0.5	-0.1	-0.1	0.8	-0.6	-1.8	-1.9	-0.1	-1.8
Pulse wave Arterial Stiffness index	1.0	1.2	2.9	1.7	-0.8	0.9	-0.7	-1.1	0.3	-1.7	0.8	-1.1
Comparative body size at age 10	1.0	2.9	11.4	-3.4	1.7	-1.6	1.3	-0.4	-0.5	1.9	-1.4	1.1
Long-standing illness, disability or infirmity	1.0	1.5	3.5	-0.8	1.9	-1.1	1.2	1.2	-0.8	1.1	-1.0	1.3
Qualifications: nursing, teaching	1.0	1.6	5.1	-0.5	2.2	-1.0	-0.3	-1.1	-1.9	-0.8	-1.7	-0.4
Back pain experienced in last month	1.0	1.4	5.8	-0.2	2.4	-0.0	1.2	0.7	-1.4	0.8	-1.6	0.2
Medication: Aspirin	1.0	1.3	2.2	-1.4	-0.3	-1.1	1.0	-1.5	-1.1	-1.0	-1.3	-0.9
Medication: Bendroflumethiazide	1.0	1.5	3.7	0.3	-1.0	0.6	-1.6	-1.9	-0.3	-1.8	-0.8	-1.4
Average weekly beer plus cider intake	1.0	1.5	3.6	-0.9	-1.4	-0.1	-0.7	-1.9	-0.4	-1.7	-0.7	-1.7
Irritability	1.0	1.8	7.3	-1.8	1.1	-2.7	1.4	0.8	-1.0	-0.5	-0.3	-0.1
Crohns Disease (2012)	0.9	1.5	4.9	-0.4	0.7	-0.8	-0.7	1.0	1.7	2.2	0.2	1.7
Rheumatoid Arthritis	0.9	1.3	2.8	-0.4	0.3	0.1	-0.3	-1.7	-1.7	-0.8	-1.6	-1.5
Waist Hip Ratio (WHR)	0.9	4.0	11.8	3.4	-1.4	1.7	-0.6	1.1	2.8	0.6	2.9	0.7
Type 2 Diabetes (T2D) (2018)	0.9	1.7	5.8	2.4	-1.3	2.2	-0.3	0.4	1.0	0.3	1.2	0.3
Medication for hormone replacement therapy	0.9	1.0	5.0	0.9	-0.3	2.2	-0.5	-0.8	-0.4	-0.6	0.2	-1.3
Pack years adult smoking proportion	0.9	1.4	2.5	-1.5	1.3	-1.2	1.4	0.7	0.9	1.6	-0.2	0.9
Leg fat-free mass (left)	0.9	4.5	9.2	-2.3	1.9	-2.7	1.6	-1.4	2.0	1.9	-3.0	1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.2	5.1	-0.6	-0.1	1.2	-0.4	-2.3	-1.7	-0.9	-2.0	-2.1
Multivitamins +/- minerals	0.9	1.1	6.0	-0.3	0.7	-0.9	1.4	0.4	-2.5	-0.0	0.1	-0.9
Body mass index (BMI)	0.9	3.8	9.1	-2.4	2.3	-2.1	1.9	-1.5	0.5	1.4	-3.0	1.0
Financial difficulties in last 2 years	0.9	1.2	4.0	0.1	1.1	0.2	1.1	2.0	0.3	1.4	0.5	1.3
Medication: Simvastatin	0.9	1.3	6.1	-1.0	1.2	-2.5	0.6	-0.3	0.2	0.6	-1.1	0.8
Impedance of arm (left)	0.9	4.4	10.0	3.2	-2.4	2.5	-1.8	1.3	1.1	-1.3	3.0	-0.6
Gout (self-reported)	0.9	1.3	2.9	0.4	0.2	-1.2	1.5	1.0	1.0	1.6	0.4	1.7
Health satisfaction	0.9	1.2	3.5	0.9	-1.5	-0.8	-0.8	-0.6	1.9	-0.5	1.6	0.1
Medication: Allopurinol	0.9	1.1	3.0	0.4	0.7	-1.3	1.0	0.5	0.7	1.7	-0.5	1.7
Number of full sisters	0.9	1.0	3.0	0.4	-0.9	1.7	-1.0	-0.8	-0.8	-1.2	-0.2	-1.4
Leg pain on walking	0.9	1.1	4.2	0.5	-0.8	0.6	-0.5	-2.1	0.2	-1.6	-0.3	-1.4
Medication: Aspirin	0.9	1.2	2.1	-1.2	-0.5	-1.4	1.0	-1.4	-0.9	-0.9	-1.1	-0.9
Leg fat-free mass (right)	0.9	4.8	10.6	-2.2	2.0	-2.8	1.4	-1.4	1.8	1.9	-3.3	2.1
Medication: Gliclazide	0.9	1.1	3.7	1.2	-1.2	1.9	0.5	0.3	-0.2	-0.2	1.4	-0.7
Smoking status: Current	0.9	1.5	3.7	-1.3	-0.1	-1.4	1.9	1.5	0.5	1.4	0.9	0.8
Leg predicted mass (right)	0.9	4.8	10.9	-2.2	2.1	-2.9	1.4	-1.4	1.8	1.8	-3.3	2.0
Guilty feelings	0.9	1.3	3.6	-0.1	0.3	-1.3	0.2	-0.8	-1.9	-1.7	0.1	-1.8
Alzheimer’s Disease (in mother)	0.8	0.9	3.6	-0.6	0.6	-1.9	-0.3	-0.5	-0.7	0.6	-1.4	0.9
Coronary Artery Disease (CAD)	0.8	1.0	3.2	1.2	-0.6	1.8	-1.1	-0.1	1.4	-0.2	1.0	0.1
Neuroticism (2016)	0.8	1.1	2.7	-1.3	-0.3	-1.6	0.9	-0.9	-1.0	-1.0	-0.7	-1.1
Lung FVC	0.8	4.0	8.9	-1.3	2.4	-3.0	2.4	2.3	-1.5	1.4	0.9	1.8
Relative age voice broke	0.8	1.2	2.8	0.0	-0.6	1.1	-1.1	-0.3	-0.1	-1.6	1.7	-1.5
Sitting height	0.8	5.8	17.0	-0.4	2.1	-2.1	1.1	1.8	3.1	3.4	-0.5	4.1
Leg predicted mass (left)	0.8	4.3	9.1	-2.2	1.8	-2.6	1.5	-1.5	2.0	1.8	-3.0	1.9
Impedance of arm (right)	0.8	3.7	9.2	3.0	-2.0	2.2	-1.6	1.5	0.6	-1.0	3.0	-0.5
Hip circumference	0.8	3.4	5.6	-1.8	2.4	-1.9	2.0	-0.5	1.6	2.0	-2.0	1.9
Pulse rate	0.8	1.4	5.4	0.6	-0.6	-1.6	1.2	0.8	0.9	0.4	2.3	0.5
Lung cancer (father)	0.8	0.9	3.6	-1.9	0.6	-0.1	0.7	-0.8	0.1	1.2	-1.2	0.1
Blood clot in the leg (DVT)	0.8	1.0	2.2	1.3	-0.7	1.5	-0.7	0.3	1.4	0.5	1.4	0.3
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	2.6	1.5	-1.0	1.6	-1.2	1.2	0.7	0.7	1.4	0.2
Pulse wave peak to peak time	0.8	0.9	2.7	-1.4	0.7	-0.7	0.4	1.0	-0.0	1.6	-0.6	1.0
Overall health rating	0.8	1.8	3.8	0.8	-0.4	-0.4	1.0	1.8	1.9	1.4	1.9	1.3
Age at last live birth	0.8	1.2	2.8	1.7	-1.2	0.4	-1.2	0.6	0.8	-1.3	1.4	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.3	-1.0	0.1	1.0	0.1	-1.3	-1.1	-0.3	-1.8	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.1	-1.7	0.4	-1.1	0.6	-1.8	-1.0	0.0	-1.7	-0.4
Asthma (self-reported)	0.8	1.6	4.1	2.0	-0.2	0.8	0.4	1.1	1.9	1.0	1.8	0.6
Illnesses of father: High blood pressure	0.8	1.1	2.8	-0.0	1.6	-0.9	1.7	-0.9	-1.0	0.4	-0.2	-1.0
Ever depressed for a whole week	0.8	1.0	2.0	0.6	-1.0	0.9	-1.4	-1.2	0.0	-1.2	-0.9	-0.9
Unable to work because of sickness or disability	0.8	1.0	2.6	-0.1	1.1	0.2	1.5	1.6	0.7	1.1	0.5	1.1
Pain experienced in last month	0.8	1.4	5.4	0.5	-2.3	0.1	-0.7	0.5	1.4	0.1	2.0	0.7
Alzheimer’s Disease (in father)	0.7	0.8	3.4	-0.7	0.4	-0.9	1.8	0.8	-0.3	1.0	-0.2	0.4
HDL Cholesterol	0.7	1.2	2.8	-1.0	1.7	-1.3	1.2	0.8	-1.6	0.6	-0.8	0.1
Primary Biliary Cirrhosis	0.7	1.0	3.7	-0.6	1.0	0.4	0.4	-0.4	-1.9	-1.2	-1.1	-1.1
Blood Platelet Count	0.7	7.8	17.9	2.9	-4.2	4.2	-1.8	-0.6	1.9	-1.1	3.8	-1.9
Past tobacco smoking	0.7	1.3	3.1	-1.0	0.2	-1.7	1.6	0.2	1.6	1.2	-0.4	0.9
Nervous feelings	0.7	1.3	3.2	-0.7	-1.2	-0.9	-0.1	-1.5	-0.5	-1.5	-0.9	-1.8
Pain all over the body in last month	0.7	0.8	3.7	0.3	-0.4	-0.3	-0.1	1.3	0.4	0.9	1.9	0.7
Weight	0.7	3.6	6.1	-1.8	2.3	-2.1	1.8	-1.0	1.8	1.8	-2.5	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.4	-1.1	1.1	-0.8	1.2	1.2	0.8	1.5	-0.4	1.3
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.4	-0.4	-1.6	0.2	-0.8	-0.8	-0.1	-1.6	0.2	-1.3
Exposure to tobacco smoke outside home	0.7	1.0	3.1	0.4	-1.3	1.3	0.5	-0.4	1.8	0.3	1.1	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.3	0.3	-1.4	0.1	-1.5	-1.1	0.6	-1.0	0.4	-0.7
Hypertension (Self-reported)	0.7	1.9	3.6	-1.9	1.4	-1.9	1.2	-1.3	-0.8	0.8	-1.8	0.5
Whole body fat-free mass	0.7	4.0	7.3	-2.2	2.1	-2.7	1.5	-1.1	1.6	1.7	-2.7	1.9
Average weekly red wine intake	0.7	1.0	3.3	1.0	0.7	0.9	-1.5	-0.0	0.2	0.4	1.8	1.0
Commuting to job workplace: Walk	0.7	0.8	1.9	0.8	-0.6	1.4	-0.7	0.9	0.6	-0.6	1.4	0.1
Medication for cholesterol	0.7	1.1	2.8	1.0	-1.4	0.9	0.3	1.4	0.6	-0.7	1.7	0.0
Whole body water mass	0.7	4.0	7.2	-2.2	2.1	-2.7	1.6	-1.1	1.4	1.7	-2.7	1.8
Medication: Blood pressure	0.7	1.2	2.8	-1.1	1.2	-1.7	-0.1	-0.7	0.2	1.4	-1.4	1.1
Basal metabolic rate	0.7	3.8	6.5	-2.1	2.1	-2.5	1.6	-1.0	1.7	1.8	-2.5	1.9
Arm fat-free mass (left)	0.7	3.7	6.0	-2.3	2.3	-2.4	1.6	-0.7	1.3	1.9	-2.3	1.8
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.5	1.2	-0.6	1.2	-0.2	0.6	1.1	0.6	1.6	0.5
Pack years of smoking	0.7	1.0	2.1	-1.5	1.2	-1.1	1.0	0.2	0.8	1.3	-0.6	0.7
Alzheimer’s Disease (including proxy)	0.6	0.8	3.1	-0.2	0.7	-1.8	0.9	0.0	-1.0	0.7	-0.9	0.9
Bipolar Disorder (2011)	0.6	0.5	2.6	0.3	-0.8	0.3	-0.3	-0.9	1.6	-0.1	-0.4	0.7
Lupus	0.6	1.0	3.3	-1.8	0.0	-1.8	1.0	0.8	-0.9	0.2	-0.0	0.2
Triglycerides	0.6	1.0	3.3	1.3	-1.8	0.6	-0.6	-0.9	1.4	-0.4	0.6	0.1
Ulcerative Colitis	0.6	0.8	2.9	1.7	-0.9	1.3	-0.6	0.4	0.5	0.5	1.0	0.2
BMI	0.6	3.5	8.5	-1.9	1.9	-1.2	1.6	-2.3	1.8	1.5	-2.9	0.7
Allergy or Eczema	0.6	1.5	7.8	-0.2	0.3	-0.3	-0.5	-0.7	-2.8	-1.0	-1.2	-1.5
Medication: Co-codamol	0.6	0.7	1.9	-1.1	0.9	-1.0	0.6	-0.6	-0.3	0.5	-1.4	-0.1
Medication: Metformin	0.6	0.9	3.0	0.5	-0.5	0.4	0.9	0.1	1.7	1.4	0.2	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.9	2.6	0.2	-1.3	0.6	0.5	-0.8	-0.9	-1.1	-0.2	-1.6
High blood pressure (mother)	0.6	0.9	3.4	-0.3	1.8	-1.2	0.7	0.5	-0.9	0.5	-1.0	0.3
Trunk fat-free mass	0.6	3.3	6.2	-2.2	2.1	-2.5	1.6	-0.7	1.2	1.5	-2.1	1.6
Alcohol intake versus 10 years previously	0.6	1.0	4.0	-0.0	-2.0	0.3	-0.1	-1.1	1.2	-1.1	0.1	-0.9
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	6.2	0.5	0.8	-0.6	0.8	2.5	0.5	1.5	1.6	2.2
Trunk predicted mass	0.6	3.3	6.2	-2.1	2.1	-2.5	1.6	-0.7	1.3	1.6	-2.1	1.6
Breastfed as a baby	0.6	0.8	2.2	-0.1	1.5	-0.9	0.6	0.5	0.0	0.9	-0.5	1.5
Hair/balding pattern: Pattern 4	0.6	1.4	3.9	1.1	-2.0	0.3	-1.1	0.2	2.0	-0.4	1.3	0.2
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.9	1.2	1.4	-0.9	-0.5	0.2	1.0	0.4	0.5	1.7
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.2	-0.6	-0.5	0.1	0.8	-1.1	-0.4	-1.1	-0.6	-1.5
Arm fat-free mass (right)	0.6	2.9	5.2	-1.9	2.0	-2.0	1.4	-0.8	1.4	1.5	-2.3	1.5
Shortness of breath walking on level ground	0.6	0.7	2.6	1.2	0.0	0.4	-0.1	0.3	1.6	0.3	1.1	0.5
Medication: Seretide 50 evohaler	0.6	0.6	2.0	1.4	0.3	0.4	0.5	1.0	0.5	0.4	1.4	0.0
Diabetes diagnosed by doctor	0.6	1.0	2.5	1.2	-0.3	0.5	1.1	1.0	1.6	0.8	1.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.0	-0.2	1.6	-0.7	0.2	1.7	0.1	1.3	0.6	1.7
Commuting to job workplace: Public transport	0.6	0.7	1.6	1.1	-0.5	1.2	-1.3	-0.6	0.7	-0.3	0.9	0.2
Alcohol drinker status: Previous	0.6	0.7	2.4	-0.3	0.2	0.5	0.3	-0.9	-1.6	-0.2	-0.9	-1.4
Leg fat mass (left)	0.6	2.3	4.6	-1.5	2.1	-1.5	1.8	-0.2	1.1	1.8	-1.4	1.3
Arm predicted mass (left)	0.6	3.2	5.1	-2.2	2.1	-2.2	1.4	-0.8	1.3	1.7	-2.2	1.6
Breast Cancer	0.5	1.2	5.0	-0.9	-0.8	0.9	-0.7	0.0	-2.2	-0.8	0.1	-1.4
Respiratory disease	0.5	1.2	4.2	2.1	-0.2	0.9	-0.0	0.6	1.4	-0.1	1.8	0.1
Relative age of first facial hair	0.5	1.0	5.2	0.4	-0.7	0.6	-0.7	0.6	0.5	-0.8	2.3	-1.0
Angina	0.5	0.6	1.5	-0.4	-0.5	-0.4	0.9	-0.7	-0.7	-1.2	-0.5	-1.2
High blood pressure	0.5	1.3	3.0	-1.4	1.1	-1.3	1.1	-1.4	-0.8	0.5	-1.7	0.2
Hayfever, allergic rhinitis or eczema	0.5	1.2	4.4	-0.1	-0.1	0.2	-0.3	-1.1	-2.1	-1.0	-1.0	-1.7
Stomach or abdominal pain in last month	0.5	0.7	1.8	0.1	0.2	1.2	0.1	1.3	-0.1	1.3	0.1	1.1
Waist circumference	0.5	2.0	5.0	-0.5	1.4	-1.1	1.6	-0.8	2.2	1.7	-1.2	1.4
Forced vital capacity (FVC)	0.5	2.1	5.0	0.5	0.8	-1.8	1.0	2.1	0.6	1.3	1.5	2.2
Qualifications: None of the above	0.5	1.1	3.9	-1.3	0.5	-0.0	2.0	1.5	-0.4	1.2	-0.2	0.3
Number of live births	0.5	0.8	1.3	-0.7	1.1	-1.1	1.2	0.7	-0.6	1.1	-0.3	0.8
Qualifications: A levels/AS levels or equivalent	0.5	1.0	2.3	1.0	1.2	-1.5	-1.3	-0.3	0.8	-0.2	0.2	1.3
Medication: Cholesterol lowering	0.5	0.8	1.9	-1.4	-0.1	-0.5	0.4	-1.2	-0.7	-0.7	-1.2	-0.9
Arm fat mass (right)	0.5	2.1	3.6	-1.3	1.8	-1.5	1.5	-1.2	1.2	1.2	-1.9	1.0
Length of working week for main job	0.5	0.5	2.5	-0.6	0.0	0.4	-1.1	-0.1	-1.6	-0.1	0.0	-0.6
Exposure to tobacco smoke at home	0.5	0.6	1.4	-0.8	0.7	-1.1	1.2	0.8	-0.1	0.3	1.0	0.1
Tense / ‘highly strung’	0.5	0.8	1.6	-0.8	0.2	-1.1	0.9	0.8	-0.8	-0.9	1.1	-1.3
Medication: Amlodipine	0.5	0.7	1.8	-0.7	1.1	-0.7	0.2	0.4	-0.9	0.8	-1.3	1.0
Medication for pain relief, constipation, heartburn	0.5	0.8	1.9	0.7	-1.4	0.6	-1.2	-1.2	0.2	-0.8	0.3	-0.6
Leg fat mass (right)	0.5	1.9	3.6	-1.3	1.9	-1.4	1.8	-0.3	1.3	1.6	-1.2	1.1
Arm predicted mass (right)	0.5	2.6	4.5	-2.0	1.8	-2.0	1.3	-0.9	1.2	1.4	-2.1	1.4
Number of self-reported non-cancer illnesses	0.5	0.9	3.9	-0.7	1.7	-0.3	2.0	0.5	-0.2	0.4	-0.6	0.2
Number of operations (self-reported)	0.5	0.7	1.5	-0.2	0.4	-0.2	1.2	0.9	1.2	1.0	0.6	1.1
Age started oral contraceptive pill	0.5	0.7	2.2	-1.1	-0.1	-0.4	-0.7	-1.5	-0.2	-0.0	-1.2	-0.5
Vascular/heart problems diagnosed by doctor	0.5	1.4	4.2	1.3	-0.5	1.2	-1.0	2.0	0.7	0.3	1.8	0.6
Crohns Disease (2017)	0.4	0.8	2.6	-0.3	0.8	-0.4	-0.8	0.5	1.2	1.6	-0.2	1.1
Ulcerative Colitis (UC)	0.4	0.7	2.1	1.4	-0.7	1.4	-0.6	0.6	0.2	0.3	1.1	-0.1
Age at First Birth	0.4	0.6	1.4	-1.1	0.3	-1.0	0.0	-0.1	1.2	0.7	-0.6	1.2
LDL Cholesterol	0.4	0.6	1.5	-0.5	-0.0	0.1	0.1	-0.3	1.2	1.1	-1.0	1.1
Supplements: Zinc	0.4	0.5	0.9	-0.6	-0.8	0.9	-0.6	-0.5	-0.6	-0.5	-0.8	-0.9
Diabetes (father)	0.4	0.5	1.3	-0.7	0.6	-0.9	0.4	-0.8	-1.1	-0.2	-0.7	-0.5
Trunk fat mass	0.4	1.5	3.0	-0.7	1.4	-1.2	1.3	-0.9	1.7	1.1	-1.4	1.0
Diabetes (self-reported)	0.4	0.7	1.4	0.5	-0.1	0.9	1.2	0.7	1.2	1.1	0.3	0.9
Medication: Ramipril	0.4	0.5	1.8	-0.7	-0.5	-0.4	0.1	-0.5	-1.3	-0.4	-0.6	-1.0
Father’s age at death	0.4	0.5	2.0	-0.1	-0.1	0.4	-1.1	-1.4	-0.3	-0.9	-0.5	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	3.6	-0.1	1.0	-1.0	0.5	1.8	0.2	1.1	0.4	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	1.2	-1.0	0.7	-0.9	1.1	0.9	-1.1	0.4	-0.7	0.1
Pulse wave reflection index	0.4	0.6	1.1	0.5	-0.2	0.6	-0.1	-0.9	-0.9	-1.1	-0.7	-1.1
Number of children fathered	0.4	0.4	1.3	-0.6	0.3	0.3	-0.6	-1.1	-0.1	-1.1	-0.2	-0.5
Age at first live birth	0.4	0.7	1.9	1.3	-0.1	-0.3	-1.1	0.5	1.4	-0.5	0.4	0.8
Emphysema/chronic bronchitis	0.4	0.4	1.2	-0.3	1.1	0.7	-0.0	-0.5	-0.7	-0.4	-0.3	-1.0
Angina (self-reported)	0.4	0.5	2.2	-0.5	-0.1	-0.8	1.5	-0.1	-0.3	-0.7	-0.2	-0.7
Medication: Omeprazole	0.4	0.4	1.8	-0.1	-0.3	0.2	0.8	-0.0	-1.4	-0.4	-0.2	-1.0
Whole body fat mass	0.4	1.6	2.3	-1.1	1.4	-1.3	1.5	-1.0	1.5	1.1	-1.4	0.9
Pulse rate, automated reading	0.4	1.4	4.0	1.3	-2.0	-0.6	0.2	-1.0	1.7	-0.3	1.6	-0.2
Had major operations	0.4	0.5	1.7	0.6	-0.7	1.3	-0.1	0.6	0.8	0.3	0.7	0.4
Arm fat mass (left)	0.4	1.8	4.4	-1.3	1.4	-1.2	1.1	-1.7	1.3	0.8	-2.1	0.6
Wears glasses or contact lenses	0.4	0.5	1.6	1.3	-0.1	-0.6	0.3	0.6	0.5	0.3	0.9	1.0
Ever taken oral contraceptive pill	0.4	0.4	1.1	0.7	0.1	0.6	-0.2	0.0	-0.5	-1.0	0.6	-1.1
High cholesterol (Self-reported)	0.4	0.8	2.2	-1.1	0.8	-1.1	0.7	-0.9	-0.4	0.5	-1.5	-0.1
Heart disease (siblings)	0.4	0.5	1.7	1.0	-0.2	1.3	0.4	-0.4	0.4	-0.7	0.5	-0.5
Irritable Bowel Disease (IBD)	0.3	0.7	2.0	0.7	0.2	0.4	-0.9	0.9	0.8	1.4	0.8	0.8
Smoking Status	0.3	0.8	4.3	-1.1	0.7	-0.2	0.6	0.9	-2.1	0.1	0.4	-0.3
Hypothyroidism (self reported)	0.3	0.7	1.8	0.8	-0.7	1.0	-0.7	-0.2	-0.4	-0.9	1.1	-1.3
Lung FEV1/FVC ratio	0.3	1.4	3.5	-0.7	0.7	1.5	1.0	1.9	-0.4	1.8	-0.5	1.1
Hearing difficulty/problems: Yes	0.3	0.4	0.9	-0.8	-0.4	-0.6	0.3	-1.0	-0.6	-0.5	-0.8	-0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.9	0.5	1.4	0.2	0.6	0.3	-0.3	0.5	-0.6	0.5
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.7	0.4	-0.1	0.7	1.3	0.4	-0.0	-0.3	0.3	-0.7
Serious illness, injury or assault to yourself	0.3	0.3	1.8	0.3	0.4	0.1	0.1	0.8	-1.3	0.2	-0.3	-0.1
Supplements: Glucosamine	0.3	0.4	1.4	0.1	1.2	0.2	0.1	-0.0	-0.2	0.7	-1.1	0.2
Medication: Levothyroxine sodium	0.3	0.6	1.3	0.9	-1.0	0.9	-0.8	0.2	0.8	-0.0	1.2	-0.2
Arm fat percentage (right)	0.3	1.3	2.9	-1.0	1.6	-0.9	1.4	-1.3	0.8	0.8	-1.7	0.4
Illnesses of mother	0.3	0.4	1.6	0.1	-0.5	1.0	0.3	0.6	-0.3	-0.1	1.3	-0.2
Peak expiratory flow (PEF)	0.3	0.7	1.8	0.7	-0.1	1.3	-1.1	1.0	-0.1	0.6	0.8	0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	2.7	1.1	-0.8	0.6	-0.1	0.6	0.3	-0.3	1.6	-0.5
Eye problems/disorders: None of the above	0.3	0.3	0.8	-0.9	0.2	-0.3	-0.6	-0.9	-0.6	0.1	-0.6	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.7	-0.1	0.3	0.9	-1.3	-0.1	-0.0	0.1	0.2	0.4
Arm fat percentage (left)	0.3	1.2	3.2	-0.9	1.3	-0.6	1.3	-1.5	0.9	0.5	-1.8	0.2
Eye problems/disorders: Cataract	0.3	0.3	0.7	0.6	-0.3	-0.3	0.5	0.6	0.6	-0.2	0.9	0.5
Medication: Atorvastatin	0.3	0.4	0.8	-0.6	0.2	-0.9	0.9	-0.9	0.2	0.6	-0.6	0.3
Diastolic blood pressure, automated reading	0.3	1.1	3.0	1.1	-0.4	-1.7	0.9	0.4	1.4	0.8	0.5	1.2
Myopia	0.3	0.5	1.5	0.3	0.5	-1.2	-0.6	-1.1	0.2	-0.8	0.2	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	1.6	0.4	0.2	-0.2	1.3	0.6	-0.8	0.1	0.2	-0.4
Blood Red Count	0.2	1.5	4.8	-0.2	2.1	-0.3	1.0	-0.5	0.4	1.4	-2.2	0.9
Hair Pigment	0.2	5.3	12.2	-1.1	3.0	-2.5	3.5	2.9	-1.0	2.2	1.0	1.9
Trunk fat percentage	0.2	0.8	2.8	-0.0	0.9	-0.6	0.8	-0.7	1.7	0.8	-0.7	0.9
Age when periods started (menarche)	0.2	0.5	1.3	-0.4	0.1	0.5	1.1	1.1	-0.8	0.3	0.9	0.1
Chronic bronchitis/emphysema (father)	0.2	0.3	0.9	-0.4	-0.1	-0.8	0.9	0.0	0.7	0.2	0.3	-0.0
Had other major operations	0.2	0.2	0.6	0.6	-0.4	0.8	0.2	-0.5	0.7	-0.2	-0.4	0.2
Allergy	0.2	0.5	1.6	-0.4	0.1	-1.0	0.3	0.5	1.1	0.5	-0.4	1.3
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.3	0.7	-1.1	-0.3	0.0	0.0	-0.1	-0.4	0.8	-0.4
Falls in the last year	0.2	0.3	1.3	-0.2	1.1	-0.7	0.2	-0.6	0.7	-0.2	0.2	0.2
Noisy workplace	0.2	0.2	1.2	0.0	0.1	1.1	0.4	0.3	-0.3	-0.4	0.4	-0.5
Medication: Lansoprazole	0.2	0.2	0.6	0.4	0.8	-0.2	0.5	0.5	0.2	0.3	-0.3	0.7
Standing height	0.2	1.7	8.3	0.8	0.5	-0.6	0.0	0.9	2.9	0.9	0.7	1.9
Glaucoma (self-reported)	0.2	0.3	1.0	-0.5	0.5	0.7	-0.3	1.0	-0.6	0.0	-0.1	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	1.8	0.5	0.5	-1.1	-0.2	1.1	0.5	0.5	0.6	1.3
Body fat percentage	0.2	0.8	1.7	-0.4	1.3	-0.6	1.3	-0.6	1.2	0.9	-0.7	0.7
Leg fat percentage (right)	0.2	0.6	1.7	-0.5	1.2	-0.0	1.3	-0.1	0.6	1.1	-0.2	0.3
Heart disease (mother)	0.2	0.2	0.8	-0.3	-0.2	0.1	-0.7	-0.9	0.4	0.2	-0.7	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.5	-0.1	-0.6	0.2	0.4	0.4	-0.7	0.5	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.1	-0.1	-0.0	1.0	-0.9	-0.5	-0.4	-0.6	-0.6	-0.7
Loneliness, isolation	0.2	0.3	1.2	-0.9	-0.2	-0.6	1.1	-0.0	0.5	-0.2	0.3	-0.5
Ever had bowel cancer screening	0.2	0.3	0.8	0.7	0.5	0.2	-0.9	0.7	0.4	0.0	0.2	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.6	0.2	-0.3	0.7	-0.8	0.1	0.5	0.3	-0.1	0.4
Breast cancer (self-reported)	0.2	0.3	1.6	-0.5	-0.2	-0.1	-0.0	0.1	-1.3	-0.2	0.1	-0.6
Hearing aid user	0.2	0.3	0.6	-0.3	-0.3	-0.5	0.7	0.6	-0.8	0.1	0.6	-0.0
Financial situation satisfaction	0.2	0.3	0.6	-0.2	0.7	-0.5	0.8	0.1	0.7	0.4	0.4	0.4
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	-0.6	-0.3	0.9	-0.6	0.5	-0.3	-0.3	-0.4	-0.2
Ever smoked	0.2	0.4	1.0	0.7	0.5	0.6	-0.5	0.8	-1.0	-0.1	0.9	-0.0
Leg fat percentage (left)	0.2	0.8	2.9	-0.6	1.7	-0.3	1.3	0.2	0.4	1.3	-0.5	0.6
Supplements: Calcium	0.2	0.2	0.5	-0.4	0.4	-0.5	0.4	0.1	-0.5	0.6	-0.7	0.1
Blood Eosinophil Count	0.1	0.7	1.6	-0.8	0.5	-0.9	-0.5	-0.9	-1.3	-0.5	-1.2	-0.6
Height	0.1	2.2	5.0	-0.4	1.9	-2.2	1.3	1.3	0.7	1.2	-0.6	2.2
Tanning	0.1	0.8	2.0	0.2	-0.9	-0.1	-0.4	-1.0	-1.4	-0.8	-0.5	-1.4
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.3	0.5	-0.4	0.6	0.2	-0.2	0.4	-0.1	-0.1
Had menopause	0.1	0.2	0.8	-0.1	0.5	-0.0	0.9	-0.1	-0.4	-0.0	-0.6	-0.1
Comparative height size at age 10	0.1	0.7	4.0	0.8	-0.1	0.1	-0.1	-0.7	2.0	0.2	-0.5	0.7
Blood White Count	0.0	0.2	0.6	-0.3	-0.8	-0.1	0.6	-0.3	-0.2	-0.3	0.5	-0.3

Hub : Genes

LRRC4

Models

Trait associations