Best TWAS P=3.32e-11 · Best GWAS P=1.52e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TTC26 | 0.06 | 0.03 | lasso | 4 | 0.03 | 1.0e-04 | 6.7 | 6.6 | 3.3e-11 | 0.97 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ZC3HAV1 | 0.32 | 0.14 | enet | 16 | 0.20 | 6.4e-15 | 5.6 | 5.1 | 3.0e-07 | 0.49 | 0.59 | 0.41 | FALSE |
| 3 | GTEx | Testis | PARP12 | 0.21 | 0.07 | lasso | 8 | 0.05 | 2.7e-03 | -4.9 | 5.2 | 1.5e-07 | -0.01 | 0.01 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | PARP12 | 0.02 | 0.01 | blup | 68 | 0.01 | 2.4e-02 | -4.7 | 5.7 | 1.2e-08 | -0.05 | 0.02 | 0.78 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | PARP12 | 0.14 | 0.11 | enet | 10 | 0.12 | 9.4e-12 | -4.9 | 5.1 | 3.0e-07 | -0.08 | 0.02 | 0.98 | FALSE |