TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (right)
:
←
→
chr7:138,030,784-140,449,834
Best TWAS P=3.32e-11 · Best GWAS P=1.52e-11 conditioned to 1
138M
138.5M
139M
139.5M
140M
140.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
TTC26
0.06
0.03
lasso
4
0.03
1.0e-04
6.7
6.6
3.3e-11
0.97
0.00
1.00
TRUE
4
The Cancer Genome Atlas
Lung Adenocarcinoma
PARP12
0.02
0.01
blup
68
0.01
2.4e-02
-4.7
5.7
1.2e-08
-0.05
0.02
0.78
TRUE
3
GTEx
Testis
PARP12
0.21
0.07
lasso
8
0.05
2.7e-03
-4.9
5.2
1.5e-07
-0.01
0.01
0.93
FALSE
2
GTEx
Cells Transformed fibroblasts
ZC3HAV1
0.32
0.14
enet
16
0.20
6.4e-15
5.6
5.1
3.0e-07
0.49
0.59
0.41
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
PARP12
0.14
0.11
enet
10
0.12
9.4e-12
-4.9
5.1
3.0e-07
-0.08
0.02
0.98
FALSE