TWAS hub - GCC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0300	3.6e-04	0.095	0.031	0.086	0.072	0.091	1.4e-11	9.8e-05	1.1e-10	3.8e-09	3.9e-11
2	GTEx	Brain Cortex	0.2220	0.1040	5.5e-03	0.133	NA	0.047	NA	0.047	1.6e-04	NA	2.0e-02	NA	2.0e-02
3	GTEx	Nerve Tibial	0.0882	0.0402	1.2e-03	0.062	NA	-0.001	NA	0.051	3.2e-05	NA	3.9e-01	NA	1.7e-04
4	GTEx	Whole Blood	0.0650	0.0330	9.1e-03	-0.002	NA	0.001	NA	-0.003	6.4e-01	NA	2.7e-01	NA	9.2e-01
5	METSIM	Adipose	0.0464	0.0199	3.6e-04	0.024	0.019	0.017	0.023	0.013	1.2e-04	6.3e-04	1.1e-03	1.9e-04	3.4e-03
6	ROSMAP	Brain Pre-frontal Cortex	0.0483	0.0231	3.8e-04	0.015	0.013	0.027	0.017	0.017	4.5e-03	6.9e-03	1.7e-04	2.3e-03	2.4e-03
7	YFS	Blood	0.0271	0.0086	2.8e-11	0.042	0.032	0.038	0.032	0.038	1.5e-13	1.0e-10	2.2e-12	8.8e-11	1.8e-12
8	TCGA	Brain Lower Grade Glioma	0.0516	0.0232	2.7e-06	0.072	0.049	0.054	NA	0.063	1.4e-08	2.6e-06	8.8e-07	NA	1.2e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Verbal and Numeric Reasoning (VNR)	10.9	26.1	38.1	3.6	6.0	6.0	1.1	5.6	6.2	5.0	5.3
Worrier / anxious feelings	9.7	18.2	27.7	-3.3	-5.3	-4.8	-1.4	-3.8	-4.2	-5.1	-4.8
Intelligence (Savage-Jansen 2018)	9.6	29.6	41.9	3.9	6.4	6.3	1.5	6.5	5.4	5.7	5.8
Risk taking	7.8	11.5	17.1	3.1	3.8	3.4	2.3	2.3	4.1	4.0	3.5
Birth weight	7.6	16.4	23.8	-3.4	-4.9	-4.4	-2.0	-4.0	-4.0	-4.6	-4.4
Mouth/teeth dental problems: Loose teeth	7.1	8.4	11.2	3.0	3.4	3.0	1.3	2.9	2.7	3.0	3.3
Medication: Ibuprofen	5.7	6.8	8.3	2.6	2.9	2.8	1.6	2.4	2.9	2.6	2.9
Pulse rate	5.6	9.5	14.4	3.0	2.7	2.6	3.8	2.8	3.8	2.9	2.9
Worry (Nagel 2018)	5.0	10.5	17.4	-2.4	-3.8	-4.2	-0.4	-3.2	-3.1	-3.8	-3.6
Handedness (chirality/laterality): Left-handed	4.7	5.6	11.2	-2.6	-2.7	-2.1	-0.1	-0.7	-2.8	-3.3	-2.6
Chronotype (morning person)	4.5	10.5	17.3	-3.3	-3.6	-3.3	-1.5	-2.6	-4.2	-3.5	-3.3
Fluid intelligence score	4.3	8.9	17.2	2.0	3.3	3.5	0.7	3.2	4.2	2.6	2.9
Medication: Ibuprofen (e.g. Nurofen)	4.3	5.4	7.1	2.1	2.7	2.6	1.2	2.4	2.5	2.3	2.6
Impedance of leg (right)	4.0	19.2	29.3	4.0	5.2	4.6	2.0	3.4	4.7	5.4	4.8
Illnesses of siblings: Diabetes	3.8	4.6	7.8	-1.2	-2.6	-2.5	-1.0	-1.6	-2.2	-2.8	-2.5
Schizophrenia (2018)	3.7	7.8	14.4	-2.7	-2.9	-3.0	0.2	-1.7	-3.8	-3.3	-3.1
Impedance of leg (left)	3.6	17.7	26.6	4.3	4.9	4.3	1.9	3.2	4.5	5.2	4.5
Neuroticism	3.5	8.5	11.9	-2.2	-3.2	-3.5	-1.4	-3.2	-3.4	-2.9	-2.9
Supplements: Glucosamine	3.5	4.5	17.8	-1.5	-1.6	-1.5	-4.2	-2.5	-0.1	-1.5	-1.6
Impedance of whole body	3.5	17.9	26.6	3.8	5.1	4.7	0.8	3.5	4.4	5.2	4.8
Body Mass Index (BMI) (2010)	3.4	4.7	8.0	-1.9	-2.5	-2.5	0.2	-1.7	-2.0	-2.8	-2.5
HbA1C	3.4	3.8	6.7	0.8	2.6	2.2	1.0	2.4	0.3	2.3	2.5
Chest pain or discomfort	3.4	4.9	10.4	1.2	2.6	2.3	3.2	2.2	1.0	2.0	2.4
Neuroticism (Nagel 2018)	3.3	7.7	11.6	-2.0	-3.0	-3.4	-1.9	-3.0	-2.8	-2.9	-2.8
Sensitivity / hurt feelings	3.1	5.3	7.6	-1.8	-2.8	-2.6	-1.1	-2.4	-2.1	-2.6	-2.6
Medication: Co-codamol	3.1	3.6	6.6	-1.0	-2.4	-2.3	0.7	-1.3	-1.6	-2.4	-2.6
Lung cancer (father)	3.1	3.7	4.9	-2.1	-2.0	-2.2	1.1	-1.8	-1.6	-2.1	-2.1
Hair/balding pattern: Pattern 3	3.0	4.4	7.8	-1.6	-2.5	-2.1	0.6	-1.3	-2.8	-2.5	-2.4
Birth weight of first child	3.0	5.4	8.9	-2.2	-3.0	-2.6	-0.9	-2.1	-2.5	-2.5	-2.4
Commuting to job workplace: Cycle	2.9	3.5	5.4	1.3	2.3	1.9	1.5	2.3	1.6	1.9	2.0
Impedance of arm (right)	2.8	13.3	19.0	3.3	4.4	4.2	-0.2	3.1	3.9	4.1	4.1
Fractured/broken bones in last 5 years	2.8	3.6	5.9	1.1	2.0	2.4	-1.4	1.1	2.0	2.2	2.4
Medication for cholesterol	2.7	4.1	6.2	2.1	2.3	1.9	-0.8	1.2	2.2	2.5	2.4
Medication: Atenolol	2.6	3.3	7.2	-1.6	-2.1	-1.4	-0.4	-0.9	-2.7	-2.3	-1.9
Knee pain experienced in last month	2.6	4.0	6.3	-2.3	-2.2	-1.5	-1.9	-1.4	-2.5	-2.1	-1.9
Bipolar Disorder (2018)	2.5	4.0	12.1	0.2	2.4	2.5	0.2	3.5	-0.5	1.6	2.2
Crohns Disease (2012)	2.5	4.0	9.1	-3.0	-1.7	-1.7	-0.4	-2.4	-2.5	-1.2	-1.8
Ever had prostate specific antigen (PSA) test	2.5	2.8	5.4	-0.5	-2.2	-2.1	0.4	-1.4	-1.0	-2.2	-2.3
Impedance of arm (left)	2.4	11.0	15.5	2.7	3.9	3.7	0.0	3.0	3.6	3.9	3.7
Medication: Gliclazide	2.4	2.7	6.4	1.5	1.6	1.6	2.5	1.2	1.3	1.6	1.5
Alcohol intake versus 10 years previously	2.3	3.4	7.8	1.8	1.7	1.4	2.0	1.6	2.8	1.4	1.8
Mouth/teeth dental problems: Bleeding gums	2.3	3.0	5.5	1.1	2.3	1.9	0.8	1.6	1.6	2.0	2.0
Medication: Blood pressure	2.3	4.4	7.8	-2.5	-2.4	-1.8	0.7	-1.0	-2.8	-2.3	-2.3
Leg fat-free mass (right)	2.2	11.6	18.6	-3.9	-3.8	-3.4	-1.2	-2.8	-4.3	-3.5	-3.3
Body mass index (BMI)	2.1	9.0	13.8	-2.6	-3.7	-3.7	0.8	-2.4	-2.5	-3.7	-3.5
Leg predicted mass (right)	2.1	11.3	18.8	-3.9	-3.7	-3.4	-1.2	-2.7	-4.3	-3.5	-3.3
Crohns Disease (2017)	2.0	4.4	7.8	-2.5	-2.1	-2.1	-0.6	-2.1	-2.8	-1.7	-2.1
Leg fat-free mass (left)	2.0	10.6	15.5	-3.9	-3.6	-3.3	-1.2	-2.7	-3.9	-3.3	-3.2
Leg predicted mass (left)	2.0	10.4	15.3	-3.9	-3.6	-3.3	-1.2	-2.6	-3.8	-3.3	-3.2
Neuroticism score	2.0	4.1	9.2	-1.3	-2.3	-2.4	-0.7	-1.9	-3.0	-1.8	-1.9
Heart attack	1.9	2.5	4.9	-1.0	-1.8	-1.6	1.2	-0.4	-1.6	-2.2	-1.9
Qualifications: College or University degree	1.9	5.8	7.9	2.0	2.4	2.5	2.8	2.6	2.4	2.5	2.1
Whole body fat-free mass	1.9	11.1	18.0	-3.9	-3.6	-3.4	-1.2	-3.0	-4.2	-3.2	-3.2
Whole body water mass	1.9	10.8	17.8	-3.8	-3.6	-3.3	-1.3	-2.9	-4.2	-3.2	-3.2
Heart attack/myocardial infarction (self-reported)	1.9	2.4	4.7	-1.0	-1.8	-1.6	1.4	-0.3	-1.5	-2.2	-1.9
Depressed Affect (Nagel 2018)	1.8	3.9	5.9	-1.6	-2.1	-2.0	-2.3	-2.4	-2.0	-1.5	-1.7
Happiness	1.8	2.1	4.2	0.8	1.9	2.0	-0.2	1.1	0.5	1.8	2.0
Arm predicted mass (right)	1.8	9.4	12.7	-3.4	-3.5	-3.3	-0.4	-2.9	-3.6	-3.0	-3.2
Alcohol intake frequency.	1.8	4.1	10.2	-0.7	-2.4	-2.6	1.0	-1.0	-1.5	-3.2	-2.4
Mouth/teeth dental problems: Mouth ulcers	1.8	2.9	4.7	-1.3	-2.0	-1.8	-1.5	-1.3	-1.3	-2.2	-1.9
Wears glasses or contact lenses	1.8	2.1	3.2	1.5	1.1	1.5	-1.6	1.4	1.8	1.3	1.3
Basal metabolic rate	1.8	9.8	15.2	-3.6	-3.5	-3.3	-0.9	-2.8	-3.9	-3.1	-3.0
Systolic blood pressure, automated reading	1.7	5.0	8.9	-0.8	-3.0	-2.6	-0.5	-1.8	-2.1	-2.7	-2.8
Nervous feelings	1.7	3.2	9.9	-1.6	-1.7	-1.9	-0.0	-1.1	-3.1	-1.7	-1.6
Hip circumference	1.7	7.4	10.0	-2.8	-3.2	-3.1	-1.6	-2.7	-2.3	-2.7	-2.8
Trunk predicted mass	1.7	9.6	16.7	-3.7	-3.3	-3.1	-1.2	-2.9	-4.1	-2.8	-2.9
Arm fat-free mass (right)	1.7	8.9	11.9	-3.3	-3.4	-3.2	-0.8	-2.8	-3.5	-2.9	-3.0
Comparative body size at age 10	1.7	4.8	7.7	-1.9	-2.8	-2.2	-0.1	-2.2	-1.6	-2.6	-2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	5.0	-2.2	-1.4	-1.2	-0.7	-1.0	-2.2	-1.0	-1.3
Ever had bowel cancer screening	1.7	2.0	3.1	-1.8	-1.4	-1.6	-1.3	-1.4	-0.9	-1.1	-1.6
Friendships satisfaction	1.7	2.1	4.3	0.7	1.8	1.8	0.6	2.1	-0.6	1.3	1.8
Mother’s age at death	1.7	2.2	5.3	-0.1	1.7	1.9	0.3	2.3	1.1	1.6	1.3
Alcohol drinker status: Never	1.7	2.1	4.9	-1.1	-1.7	-1.6	-0.3	-0.7	-0.7	-2.2	-1.9
Arm fat-free mass (left)	1.7	8.7	12.8	-3.3	-3.3	-3.1	-0.8	-2.8	-3.6	-2.9	-2.9
Pain experienced in last month	1.7	2.9	3.9	1.8	1.7	1.4	1.9	1.5	1.4	2.0	1.7
Arm predicted mass (left)	1.7	8.5	13.6	-3.2	-3.2	-3.1	-0.9	-2.8	-3.7	-2.8	-2.8
Respiratory disease	1.6	3.6	5.4	0.5	2.2	2.3	-1.7	1.7	1.7	2.2	2.2
Weight	1.6	8.1	11.5	-3.0	-3.4	-3.4	0.1	-2.4	-2.9	-3.1	-3.1
Trunk fat-free mass	1.6	9.4	16.8	-3.6	-3.3	-3.0	-1.1	-2.9	-4.1	-2.8	-2.9
Asthma	1.6	3.2	6.1	0.4	2.2	2.1	-0.6	1.4	1.6	2.5	2.2
Pulse rate, automated reading	1.6	5.1	21.0	1.6	1.5	1.5	4.6	2.5	1.5	1.6	1.5
Pack years of smoking	1.6	2.3	3.8	-1.7	-1.7	-1.9	-0.4	-2.0	-0.6	-1.4	-1.7
Prostate Cancer	1.5	2.0	3.3	-0.7	-1.8	-1.8	0.1	-1.5	-1.2	-1.7	-1.7
Mean Putamen Volume	1.5	1.7	5.0	-2.2	-1.2	-1.1	-1.0	-1.4	0.1	-1.3	-1.1
Fasting Glucose	1.5	1.8	4.6	1.1	1.4	1.5	-0.9	0.6	0.8	2.1	1.6
Schizophrenia (2014)	1.5	3.3	13.6	-2.0	-1.0	-1.1	1.0	0.6	-3.7	-1.8	-1.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.8	8.7	-0.8	-0.9	-0.7	-2.9	-1.5	-0.9	-0.4	-0.4
Depression (self-reported)	1.5	1.8	6.6	-1.7	-0.7	-0.5	-2.6	-1.2	-1.6	-0.1	-0.4
Length of working week for main job	1.5	1.6	6.8	0.7	0.5	0.3	2.2	0.0	2.6	0.3	0.3
Hypertension (Self-reported)	1.5	4.2	6.6	-1.4	-2.6	-2.1	1.1	-1.1	-2.5	-2.5	-2.4
Average weekly fortified wine intake	1.4	1.7	2.9	-0.2	-1.7	-1.5	-0.1	-0.8	-1.4	-1.7	-1.7
Qualifications: None of the above	1.4	3.0	9.1	-0.5	-1.8	-2.3	-1.2	-3.0	-0.7	-1.3	-1.7
Mouth/teeth dental problems	1.4	2.2	3.6	-0.9	-1.7	-1.9	-0.5	-1.8	-1.5	-1.4	-1.6
Breastfed as a baby	1.4	1.8	3.5	-0.5	-1.9	-1.8	0.4	-1.0	-1.4	-1.3	-1.7
Medication: Atorvastatin	1.4	1.7	5.3	-0.5	-1.3	-1.4	1.0	-0.6	-2.3	-1.2	-1.2
Hand grip strength (left)	1.3	3.5	8.5	-0.8	-2.2	-2.0	1.2	-0.7	-1.7	-2.9	-2.2
High blood pressure	1.3	3.5	6.4	-1.2	-2.2	-1.8	1.2	-0.7	-2.5	-2.3	-2.1
Waist circumference	1.3	4.7	6.9	-2.4	-2.5	-2.6	0.5	-2.4	-1.3	-2.2	-2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	7.2	-0.8	-1.2	-0.9	-2.7	-1.2	-1.5	-0.8	-1.0
Medication: Blood pressure	1.3	2.3	3.7	0.2	-1.9	-1.7	1.3	-0.8	-1.6	-1.9	-1.7
Suffer from ‘nerves’	1.3	2.1	3.0	-0.4	-1.6	-1.7	-1.7	-1.0	-1.1	-1.7	-1.5
Arm fat mass (left)	1.3	5.3	8.2	-2.3	-2.8	-2.9	0.8	-1.7	-1.8	-2.7	-2.6
Hearing aid user	1.3	1.5	4.4	-0.9	-1.2	-1.6	-1.0	-2.1	-0.2	-0.6	-1.1
Ever smoked	1.3	2.3	6.8	2.6	1.3	1.4	0.4	0.5	2.1	1.3	1.3
Schizophrenia vs Biploar Disorder	1.2	1.5	2.8	-0.4	-1.1	-1.6	1.4	-1.7	-0.8	-1.1	-1.3
Coronary Artery Disease (CAD)	1.2	1.4	2.1	-0.7	1.5	1.4	-1.3	0.9	-0.5	1.2	1.5
Systolic Blood Pressure	1.2	5.8	11.3	-1.3	-3.4	-2.5	-0.4	-2.0	-3.0	-2.5	-2.9
Worry too long after embarrassment	1.2	2.1	6.7	-1.2	-1.3	-1.6	-0.1	-0.8	-2.6	-1.5	-1.2
Age at last live birth	1.2	1.7	3.5	0.3	1.2	1.6	-0.9	1.9	-0.6	1.6	1.4
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	6.0	-0.2	1.0	0.8	2.4	1.3	-0.7	0.6	0.7
Breast cancer (self-reported)	1.2	1.4	3.8	1.2	-0.7	-1.1	-0.1	-2.0	1.8	-0.6	-0.8
Age at First Birth	1.1	1.6	5.7	-1.5	-1.3	-1.1	0.2	-0.0	-2.4	-1.1	-1.1
BMI	1.1	6.6	11.6	-2.9	-3.1	-2.9	1.5	-1.3	-1.7	-3.4	-2.9
Ever used hormone-replacement therapy (HRT)	1.1	1.3	7.6	1.3	0.8	0.5	0.2	0.6	2.8	0.3	0.4
Past tobacco smoking	1.1	2.0	6.6	-2.6	-1.3	-1.3	0.1	-0.7	-1.8	-1.0	-1.2
Number of live births	1.1	1.6	4.9	-0.9	-1.2	-0.9	-2.2	-1.6	-0.5	-0.8	-1.0
Arm fat mass (right)	1.1	4.6	7.3	-2.0	-2.7	-2.7	0.8	-1.6	-1.8	-2.5	-2.5
Peak expiratory flow (PEF)	1.1	2.5	4.3	1.0	1.9	2.1	0.6	1.9	0.5	1.8	1.8
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.6	1.7	0.7	0.7	0.4	1.2	2.1	-0.0	0.7
Supplements: Vitamin C	1.1	1.3	3.2	-1.1	-0.9	-0.9	-1.8	-0.2	-1.2	-1.5	-0.9
Vascular/heart problems diagnosed by doctor	1.1	2.9	5.6	0.9	2.0	1.6	-1.5	0.3	2.4	2.1	1.9
Leg fat mass (left)	1.1	4.4	7.7	-1.8	-2.6	-2.8	1.4	-1.7	-1.5	-2.3	-2.4
Bipolar Disorder or Schizophrenia	1.0	2.5	10.5	-2.0	-0.8	-0.7	0.3	0.9	-3.2	-1.6	-1.0
Reaction Time	1.0	1.9	5.8	-0.2	-1.3	-1.6	-0.4	0.4	-2.4	-1.8	-1.2
Rheumatoid Arthritis	1.0	1.4	3.3	-0.2	-1.2	-1.6	0.5	-1.1	-0.7	-1.8	-1.4
Ulcerative Colitis	1.0	1.5	2.3	1.1	1.5	1.2	0.0	1.2	1.4	1.3	1.4
Type 2 Diabetes (T2D) (2018)	1.0	1.9	4.1	1.6	1.4	1.3	0.3	1.1	2.0	1.4	1.2
Pack years adult smoking proportion	1.0	1.5	2.7	-1.6	-1.3	-1.4	-0.4	-1.6	-0.5	-1.0	-1.2
Hearing difficulty/problems with background noise	1.0	1.6	3.3	-1.1	-1.3	-1.4	0.0	-0.5	-1.6	-1.8	-1.4
Whole body fat mass	1.0	4.0	7.0	-1.7	-2.5	-2.6	1.2	-1.6	-1.3	-2.2	-2.3
Leg fat mass (right)	1.0	4.0	6.8	-1.9	-2.4	-2.6	1.5	-1.5	-1.4	-2.1	-2.2
Smoking status: Previous	1.0	1.5	5.8	2.4	1.2	1.1	-0.5	0.6	1.1	0.8	1.0
Supplements: Calcium	1.0	1.1	7.3	-0.6	-0.3	-0.2	-2.7	-0.8	-0.4	-0.3	-0.1
Heart disease (siblings)	1.0	1.3	3.2	1.8	1.0	0.9	0.2	0.8	1.6	0.9	1.0
Breast Cancer	0.9	2.2	5.1	0.1	-1.7	-2.3	-0.7	-1.9	-0.2	-1.4	-1.9
Bipolar Disorder (2011)	0.9	0.8	2.9	-1.7	-0.1	0.2	-0.5	1.0	-1.6	-0.0	-0.1
Triglycerides	0.9	1.4	4.3	1.0	1.1	1.3	0.6	2.1	0.5	1.1	1.2
Type 2 Diabetes (T2D) (2012)	0.9	1.0	3.9	-2.0	-0.2	-0.5	0.9	-0.9	-1.5	-0.2	-0.4
Waist Hip Ratio (WHR)	0.9	4.2	6.9	0.9	2.5	2.4	1.6	0.9	2.3	2.6	2.3
Number of treatments/medications taken	0.9	1.7	3.0	-0.5	-1.7	-1.7	0.8	-1.7	-0.7	-1.2	-1.5
Hearing difficulty/problems: Yes	0.9	1.4	5.1	-1.6	-0.8	-0.5	-2.3	-0.6	-1.2	-0.9	-0.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.5	1.6	1.1	1.1	0.7	1.1	1.1	0.4	0.8
Alcohol usually taken with meals	0.9	1.4	2.6	1.3	1.0	1.5	0.2	1.6	0.3	1.3	1.3
Prospective memory result	0.9	1.0	2.5	-0.0	-1.2	-1.5	0.1	-1.6	-0.6	-0.9	-1.1
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.9	0.2	1.3	1.2	0.1	0.9	1.1	1.7	1.3
Medication: Omeprazole	0.9	1.0	2.0	1.4	1.1	1.1	0.7	1.1	0.4	0.8	1.2
Leg pain on walking	0.9	1.1	2.2	-0.7	-1.3	-1.1	0.5	-0.7	-1.0	-1.3	-1.5
Mineral and other dietary supplements	0.9	1.2	3.0	0.1	1.1	1.0	1.4	0.8	0.4	1.7	1.3
Asthma (self-reported)	0.9	1.8	3.4	-0.0	1.6	1.6	-0.6	1.1	1.1	1.8	1.6
Tinnitus: Yes, now most or all of the time	0.9	1.1	2.2	-0.2	1.3	0.9	-0.2	0.8	1.4	1.5	1.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.3	1.0	0.8	1.5	-1.1	1.4	0.4	0.3	1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.1	2.2	-0.1	-1.1	-1.1	-0.6	-1.0	-1.2	-1.5	-1.3
Illnesses of father: High blood pressure	0.9	1.1	3.6	-0.4	-0.9	-0.8	1.9	-0.8	-0.6	-1.1	-1.1
Depression (Nagel 2018)	0.8	1.2	2.6	-0.0	-1.2	-1.2	-0.2	-1.4	-0.7	-1.6	-1.4
Blood Eosinophil Count	0.8	5.9	10.4	-2.0	-2.8	-2.7	-0.3	-2.2	-3.2	-2.4	-2.7
Diabetes (father)	0.8	1.0	1.8	0.8	1.1	1.4	1.0	1.2	0.3	0.6	1.3
Fed-up feelings	0.8	1.4	3.8	-0.3	-1.1	-1.1	-1.9	-1.5	-1.4	-0.4	-0.7
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	3.5	-1.1	-0.3	-0.6	1.1	-0.8	-1.9	-0.3	-0.4
Number of incorrect matches in round	0.8	1.4	3.2	-1.8	-1.0	-1.1	-0.9	-1.2	-1.4	-1.0	-0.9
Exposure to tobacco smoke at home	0.8	0.9	5.0	0.2	-0.1	-0.1	2.2	0.3	-1.3	0.2	0.0
Headache pain in last month	0.8	1.3	2.3	-1.4	-1.3	-1.2	-0.4	-1.0	-0.6	-1.5	-1.2
Exposure to tobacco smoke outside home	0.8	1.1	2.0	-0.1	1.1	0.8	1.4	1.2	1.2	0.9	1.1
Number of full sisters	0.8	0.9	4.7	-0.7	-0.7	-0.7	2.2	0.0	0.0	-0.8	-0.9
Family relationship satisfaction	0.8	1.0	2.1	1.0	1.4	1.2	-0.1	0.8	1.0	0.7	1.2
Illnesses of father: Heart disease	0.8	1.1	1.8	-1.1	-1.3	-1.2	0.8	-0.6	-0.5	-1.4	-1.3
Arm fat percentage (left)	0.8	3.1	5.3	-1.4	-2.2	-2.3	1.2	-1.1	-0.8	-2.2	-2.1
Back pain experienced in last month	0.8	1.1	6.8	0.2	-0.4	0.0	-2.6	-0.0	1.0	-0.8	-0.4
Eye problems/disorders: Glaucoma	0.8	1.0	3.0	1.2	0.7	0.5	1.7	1.3	0.6	0.4	0.6
Medication: Bendroflumethiazide	0.8	1.2	1.7	-0.5	-1.1	-1.3	1.1	-0.4	-1.3	-1.3	-1.3
LDL Cholesterol	0.7	1.0	4.4	-1.6	-0.5	-0.3	0.0	0.5	-2.1	-0.7	-0.5
Lupus	0.7	1.1	2.0	-0.5	-1.3	-1.4	0.8	-1.4	-0.9	-0.8	-1.1
Neuroticism (2016)	0.7	0.9	3.5	-0.1	-0.9	-1.1	0.4	-0.7	-1.9	-0.9	-0.8
Ever had hysterectomy (womb removed)	0.7	0.7	2.6	0.8	0.3	0.1	-1.6	-1.1	1.2	0.1	0.2
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	1.3	0.4	1.0	1.1	0.3	1.0	0.4	1.0	1.1
Multivitamins +/- minerals	0.7	0.8	3.5	1.9	0.2	0.2	1.1	0.2	1.3	-0.0	0.2
Trunk fat mass	0.7	2.9	5.0	-1.5	-2.2	-2.2	1.1	-1.2	-0.9	-1.9	-2.0
Financial difficulties in last 2 years	0.7	0.9	3.3	0.1	0.7	1.0	-1.8	0.8	-0.3	1.0	0.8
Arm fat percentage (right)	0.7	2.6	4.6	-1.2	-2.0	-2.1	1.1	-1.1	-0.8	-2.1	-1.9
Father’s age at death	0.7	1.0	1.8	-0.7	-1.1	-1.4	-0.6	-1.0	-0.4	-1.1	-1.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	4.3	1.3	1.6	1.9	-1.3	1.1	0.4	2.1	1.8
High blood pressure (siblings)	0.7	1.0	3.3	-0.7	-0.9	-0.5	-1.1	-0.4	-1.8	-1.0	-0.7
Overall health rating	0.7	1.5	2.6	1.2	1.2	1.2	0.3	1.3	1.1	1.6	1.4
Illnesses of father: None of the above (group 1)	0.7	0.9	1.8	0.0	1.0	0.8	-1.3	0.3	-0.9	1.3	1.0
Medication: Paracetamol	0.7	1.1	4.0	0.9	0.6	0.9	-1.4	0.6	2.0	0.9	0.5
Cholesterol lowering medication	0.7	1.0	2.1	-1.2	-1.2	-0.5	0.2	-0.0	-1.5	-1.2	-1.0
Major Depression (MDD)	0.6	0.7	1.5	0.3	1.0	0.7	-1.2	-0.2	1.2	0.9	0.8
Average weekly spirits intake	0.6	0.8	1.8	0.5	-1.4	-0.9	0.0	-1.2	0.5	-0.7	-1.1
Diabetes (mother)	0.6	0.7	1.8	0.1	0.9	0.9	-1.3	-0.1	0.8	1.0	0.9
Hand grip strength (right)	0.6	1.8	3.8	-0.3	-1.7	-1.5	1.0	-0.7	-1.0	-2.0	-1.5
Stomach or abdominal pain in last month	0.6	0.8	1.4	0.4	1.1	0.9	-1.2	0.6	-0.2	1.0	1.1
Pain all over the body in last month	0.6	0.7	2.8	-0.9	-0.2	-0.1	1.0	-0.7	-1.7	0.5	-0.0
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	5.3	-0.4	0.3	1.0	-2.3	0.4	-0.0	0.5	0.3
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.4	-0.2	1.0	0.9	-1.5	-0.0	1.5	0.9	0.7
Medication: Amlodipine	0.6	0.9	2.9	-1.2	-0.7	-0.4	-0.8	-0.5	-1.7	-0.7	-0.7
Age at first live birth	0.6	1.1	4.9	-1.1	0.2	0.7	-0.1	1.3	-2.2	0.5	0.4
Eye problems/disorders: None of the above	0.6	0.7	1.5	-1.0	-0.8	-0.8	0.3	-0.8	-1.2	-0.9	-0.8
Medication: Allopurinol	0.6	0.8	2.8	-1.7	-0.8	-0.5	-0.9	-0.6	-0.8	-0.7	-0.7
Heart disease (mother)	0.6	0.7	3.2	-0.4	-0.4	-0.5	1.8	0.0	-1.0	-0.7	-0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	3.2	0.7	0.5	0.5	1.8	1.3	0.3	0.0	0.4
Mood swings	0.6	1.1	3.7	-0.8	-0.9	-0.9	-1.3	-0.8	-1.9	-0.4	-0.6
Leg fat percentage (left)	0.6	2.1	4.3	-0.4	-1.7	-2.0	2.1	-1.1	-0.1	-1.4	-1.7
Age started oral contraceptive pill	0.6	0.8	1.7	-0.9	-0.9	-0.8	-0.7	-0.8	-0.4	-1.3	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.2	1.1	0.9	0.9	0.5	0.8	0.1	0.9	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.2	0.4	-0.9	-1.0	-0.2	-1.1	-0.6	-1.0	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.6	1.4	0.3	-0.1	1.6	0.3	0.6	0.1	0.2
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.7	-1.1	-1.1	-0.9	-0.5	-0.1	-1.6	-1.2	-1.1
Forced vital capacity (FVC)	0.5	2.0	3.6	1.0	1.2	1.7	-1.8	1.0	-0.2	1.9	1.6
Illnesses of mother	0.5	0.6	1.4	1.2	0.8	0.7	0.1	0.3	1.0	0.9	0.7
Loud music exposure frequency	0.5	0.5	2.2	0.3	0.5	0.1	1.5	0.9	-0.8	0.3	0.2
Leg fat percentage (right)	0.5	1.7	4.5	-0.6	-1.4	-1.7	2.1	-0.8	0.1	-1.1	-1.4
Number of full brothers	0.5	0.7	1.5	-0.0	-0.8	-1.0	1.2	-0.4	0.5	-0.8	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.0	0.5	-0.9	-0.6	1.0	-0.2	-1.0	-1.0	-0.6
Osteoarthritis (self-reported)	0.5	0.7	4.4	-0.1	0.2	0.6	-2.1	0.2	-0.5	0.2	0.4
Average weekly champagne plus white wine intake	0.5	0.7	1.6	0.2	0.6	0.7	1.1	0.6	1.2	1.1	0.6
Miserableness	0.5	0.8	2.9	-0.6	-0.9	-0.9	0.0	-1.0	-1.7	-0.6	-0.7
Commuting to job workplace: Public transport	0.5	0.6	2.4	-0.4	-0.5	-0.8	1.5	-0.8	-0.5	-0.3	-0.7
Unable to work because of sickness or disability	0.5	0.6	2.8	-0.6	-0.1	-0.0	-1.7	-0.5	-1.1	0.4	0.1
Alcohol drinker status: Previous	0.5	0.6	2.2	0.8	-0.5	-0.5	1.5	0.2	-0.1	-1.0	-0.7
Irritable Bowel Disease (IBD)	0.4	1.0	1.8	-1.3	-0.9	-1.0	-0.2	-1.3	-1.3	-0.5	-0.9
HDL Cholesterol	0.4	0.6	1.3	-0.4	-0.7	-0.7	-1.1	-1.0	-0.5	-0.8	-0.7
Primary Biliary Cirrhosis	0.4	0.6	2.7	1.6	-0.1	-0.2	1.5	0.1	0.2	-0.4	-0.1
Smoking Status	0.4	1.0	3.8	2.0	0.6	0.6	-0.7	-0.1	1.4	0.6	0.6
Cardiovascular Disease	0.4	1.3	2.5	-1.2	-1.4	-0.7	1.2	-0.4	-1.6	-1.2	-1.0
Relative age of first facial hair	0.4	0.8	1.8	-1.3	-0.8	-1.1	0.1	-1.4	0.3	-0.2	-0.8
Severe depression (siblings)	0.4	0.4	1.7	0.4	0.5	0.6	0.6	0.6	1.3	0.2	0.2
Townsend deprivation index at recruitment	0.4	0.6	1.6	0.7	0.9	0.6	0.5	0.4	0.8	1.3	0.8
Taking other prescription medications	0.4	0.5	0.9	-0.9	-0.9	-0.9	-0.5	-0.8	-0.9	-0.1	-0.6
Serious illness, injury or assault to yourself	0.4	0.4	1.6	0.0	-0.6	-0.4	-0.3	-0.6	1.3	-0.6	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.1	0.8	-0.9	-1.1	-0.6	-0.5	-0.8	-1.0	-0.8
Had other major operations	0.4	0.5	1.8	0.5	0.4	0.5	0.5	1.3	1.0	0.2	0.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	2.2	-0.6	0.2	0.2	-1.5	0.5	-0.8	-0.2	0.1
Medication: Ramipril	0.4	0.5	2.0	0.1	-0.6	-0.8	0.2	-0.4	-1.4	-0.6	-0.4
Hair/balding pattern: Pattern 4	0.4	0.9	1.6	0.6	1.2	0.7	1.0	0.9	-0.1	1.3	1.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.3	-0.2	0.6	0.6	-0.1	1.1	-1.1	0.4	0.6
Blood clot in the leg (DVT)	0.4	0.6	1.7	-1.2	0.0	-0.2	1.3	-0.2	-1.1	0.2	-0.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.8	0.7	0.7	0.1	1.1	-0.2	1.7	0.8	0.6
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.3	-0.3	0.4	0.4	-1.5	0.3	0.8	0.2	0.6
Body fat percentage	0.4	1.4	2.7	-0.4	-1.4	-1.6	1.6	-0.6	0.1	-1.2	-1.3
Wheeze or whistling in the chest in last year	0.4	0.8	2.3	-0.5	1.1	0.7	0.3	-0.4	1.1	1.5	0.8
Mean time to correctly identify matches	0.4	0.8	1.4	0.3	-0.7	-1.1	-1.1	0.5	-1.2	-1.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.3	-0.2	-0.1	-0.2	-1.8	-0.4	-0.3	0.0	-0.2
Commuting to job workplace: Walk	0.4	0.4	1.3	0.5	0.7	0.7	-0.5	0.0	0.3	1.1	0.8
Eye problems/disorders: Cataract	0.4	0.5	1.4	0.9	0.4	0.3	-1.2	0.1	0.9	0.6	0.5
Medication: Aspirin	0.4	0.5	1.4	-0.0	-0.8	-0.9	0.5	-0.2	-1.2	-0.9	-0.6
Smoking status: Current	0.4	0.6	1.7	1.0	0.3	0.2	1.2	0.4	1.3	0.6	0.4
Financial situation satisfaction	0.4	0.5	1.3	0.3	0.5	0.7	1.1	0.7	-0.7	0.5	0.5
Basal cell carcinoma (self-reported)	0.4	0.5	1.4	0.8	0.6	0.4	0.9	0.5	1.2	0.3	0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.2	-0.4	0.5	0.2	1.5	0.1	-0.6	0.7	0.4
Alzheimer’s Disease (in mother)	0.3	0.4	1.4	-0.7	-0.4	-0.3	0.3	0.2	-1.2	-0.7	-0.2
Alzheimer’s Disease (in father)	0.3	0.4	1.3	-0.4	-0.2	-0.1	-1.2	-1.0	0.5	-0.0	-0.1
Allergy or Eczema	0.3	0.8	2.3	-0.5	-0.9	-0.7	-0.5	0.0	-1.5	-1.1	-1.0
Hypothyroidism (self reported)	0.3	0.7	3.5	0.6	0.1	-0.7	1.9	-1.0	0.7	0.1	-0.1
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.8	0.0	-0.7	-0.8	0.1	-0.4	-0.7	-0.7	-0.9
Vitamin and mineral supplements	0.3	0.4	2.3	-1.5	0.0	0.0	-0.1	-0.5	-0.4	0.4	0.0
Current tobacco smoking	0.3	0.5	1.6	0.9	0.3	0.2	1.0	0.3	1.3	0.6	0.3
Maternal smoking around birth	0.3	0.4	1.5	-1.2	0.5	0.4	0.6	0.7	-0.4	0.4	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.1	-0.5	-0.7	-0.6	-1.0	-0.6	-0.0	-1.5	-0.8
Medication: Levothyroxine sodium	0.3	0.5	1.8	0.2	0.6	0.1	1.3	0.3	1.1	0.5	0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	2.7	-0.3	0.0	0.2	1.6	0.5	0.0	0.1	0.1
Illnesses of siblings	0.3	0.5	1.5	-0.1	0.7	0.4	0.9	-0.1	0.7	1.2	0.6
Time employed in main current job	0.3	0.4	1.1	0.3	-0.5	-0.7	0.8	0.4	0.3	-1.0	-0.5
Noisy workplace	0.3	0.4	0.6	0.6	0.7	0.6	0.7	0.8	0.5	0.7	0.7
Mouth/teeth dental problems: Dentures	0.3	0.5	1.2	0.7	0.6	1.1	0.1	0.8	0.9	0.6	0.6
Medication: Lansoprazole	0.3	0.3	0.6	-0.7	-0.7	-0.5	0.0	-0.6	-0.3	-0.5	-0.7
Pulse wave reflection index	0.3	0.4	1.1	-0.1	-0.4	-0.3	-1.0	-0.8	-0.8	-0.5	-0.5
Medication: Paracetamol	0.3	0.5	1.9	0.3	-0.1	0.2	-1.4	0.2	1.3	0.2	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	2.9	0.0	0.7	1.0	-1.7	0.7	-1.0	1.1	1.0
Number of children fathered	0.3	0.3	2.4	0.2	-0.0	0.3	0.1	0.3	1.6	-0.2	-0.1
Health satisfaction	0.3	0.4	1.1	0.1	0.8	0.5	0.3	0.4	0.1	1.1	0.8
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.4	0.7	-0.2	0.3	-0.4	1.2	0.6	-0.6	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.6	-0.9	-0.1	-0.2	-1.3	-0.5	-1.2	-0.1	-0.0
Average weekly red wine intake	0.3	0.5	1.5	0.1	0.5	1.1	-1.2	0.2	0.7	0.7	0.3
Qualifications: nursing, teaching	0.3	0.5	0.9	1.0	-0.5	-0.0	0.7	0.8	0.5	-0.9	-0.7
Osteoporosis (self-reported)	0.3	0.4	2.2	0.1	0.3	0.1	-1.5	-0.4	-0.2	0.7	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.6	1.3	0.5	0.7	-1.1	0.6	-0.0	0.8	0.6
Guilty feelings	0.3	0.4	1.4	0.5	-0.7	-0.8	0.1	-0.5	-1.2	-0.5	-0.6
Average weekly beer plus cider intake	0.3	0.5	0.9	-1.0	-0.5	-0.7	-0.1	-0.9	-0.8	-0.6	-0.4
Ovarian Cancer	0.2	0.3	1.6	0.6	-0.4	-0.2	-1.2	-0.2	-0.5	-0.2	-0.1
Blood Platelet Count	0.2	2.6	8.0	-0.3	1.6	0.9	2.8	0.9	1.8	1.8	1.2
Trunk fat percentage	0.2	0.9	1.6	-0.5	-1.2	-1.3	1.2	-0.4	0.2	-1.0	-1.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.6	0.2	-0.1	-0.2	-0.8	-0.6	0.5	-0.5	-0.4
Qualifications: CSEs or equivalent	0.2	0.3	0.4	0.5	0.5	0.6	-0.4	0.5	-0.3	0.6	0.6
High blood pressure (mother)	0.2	0.3	0.6	-0.6	-0.8	-0.6	-0.0	-0.4	-0.2	-0.7	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.3	0.7	-0.1	0.1	-0.9	0.2	1.1	-1.1	-0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.4	0.2	-0.1	-0.1	1.5	-0.2	0.1	0.1	-0.1
Medication: Simvastatin	0.2	0.3	1.7	0.4	-0.5	-0.1	1.3	0.5	0.2	-0.5	-0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.6	-0.7	-0.5	0.3	1.3	0.7	-0.7	-0.1	-0.5
Medication: Cholesterol lowering	0.2	0.3	1.8	0.4	-0.3	-0.4	1.3	0.2	-0.3	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	1.9	0.7	0.7	1.0	-1.4	0.6	-0.5	1.0	0.9
Tense / ‘highly strung’	0.2	0.3	1.3	1.2	0.3	-0.3	0.8	-0.0	-0.2	0.6	0.4
Glaucoma (self-reported)	0.2	0.3	1.6	0.7	0.1	0.1	1.3	0.2	0.0	0.2	-0.0
Gout (self-reported)	0.2	0.3	1.8	-1.4	-0.4	0.0	-0.0	-0.0	0.1	0.1	-0.2
Shortness of breath walking on level ground	0.2	0.2	0.7	0.1	0.5	0.4	-0.5	0.0	0.2	0.8	0.6
Medication for pain relief, constipation, heartburn	0.2	0.3	1.0	-0.6	-0.2	-0.2	-1.0	-0.6	-0.6	-0.1	-0.2
Neck or shoulder pain in last month	0.2	0.3	1.0	0.3	-0.3	0.0	-1.0	-0.4	0.1	-0.7	-0.3
Angina (self-reported)	0.2	0.3	0.6	0.8	0.6	0.6	0.1	0.4	-0.4	0.5	0.8
Migraine (self-reported)	0.2	0.3	1.0	-0.0	0.1	0.0	-1.0	-0.8	0.5	0.5	0.3
Medication: Seretide 50 evohaler	0.2	0.3	0.9	0.5	0.4	0.2	0.0	-0.1	1.0	0.8	0.4
Had major operations	0.2	0.2	0.8	-0.7	-0.1	-0.2	0.6	-0.9	0.5	0.0	-0.3
Medication: Aspirin	0.2	0.2	0.5	0.4	-0.4	-0.5	0.7	0.2	-0.7	-0.5	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.2	-0.1	-0.2	-0.4	0.7	-0.1	-1.1	-0.3	-0.2
Long-standing illness, disability or infirmity	0.2	0.3	1.4	1.2	-0.2	-0.2	-0.5	-0.1	0.6	0.0	0.1
Diabetes diagnosed by doctor	0.2	0.3	0.7	0.6	0.5	0.4	0.2	0.3	0.6	0.8	0.6
Number of self-reported non-cancer illnesses	0.2	0.3	0.8	0.5	0.1	0.3	0.9	0.9	-0.5	0.1	0.3
High cholesterol (Self-reported)	0.2	0.3	0.9	0.0	-0.6	-0.4	1.0	-0.4	-0.6	-0.8	-0.3
Number of operations (self-reported)	0.2	0.3	0.9	-0.4	-0.5	-0.4	0.5	-0.6	1.0	-0.1	-0.4
Irritability	0.2	0.3	1.8	0.6	-0.2	-0.2	0.0	0.3	-1.3	0.1	0.1
Diastolic blood pressure, automated reading	0.2	0.5	1.3	-0.4	-0.7	-0.5	1.2	0.0	-1.1	-0.2	-0.6
Ever depressed for a whole week	0.2	0.3	0.7	-0.6	0.5	0.5	-0.5	0.8	0.2	0.2	0.4
Alzheimer’s Disease (including proxy)	0.1	0.2	0.7	0.9	0.2	0.5	0.0	0.3	-0.3	0.1	0.5
Blood Red Count	0.1	0.6	3.4	0.8	0.0	0.1	1.9	0.8	0.4	-0.5	0.2
Heel T-Score	0.1	0.7	3.1	0.0	0.0	0.1	-1.1	0.9	0.3	-1.8	-0.5
Height	0.1	2.2	4.0	-1.0	-1.9	-1.8	-1.3	-2.0	-0.7	-1.0	-1.5
Lung FEV1/FVC ratio	0.1	0.4	1.4	1.2	0.6	0.4	0.3	0.3	0.7	0.3	0.5
Lung FVC	0.1	0.4	0.9	1.0	-0.9	-0.5	-0.4	-0.7	-0.8	0.1	-0.6
Angina	0.1	0.2	0.4	0.7	0.5	0.5	0.2	0.3	-0.3	0.2	0.6
Supplements: Zinc	0.1	0.1	0.2	0.0	-0.2	-0.3	0.0	-0.2	-0.4	-0.5	-0.4
Relative age voice broke	0.1	0.1	0.5	0.1	0.1	-0.2	-0.2	-0.4	0.7	0.2	-0.1
Age when periods started (menarche)	0.1	0.3	1.7	0.1	0.0	0.1	-1.3	-0.2	0.4	0.3	0.0
Sitting height	0.1	0.7	2.6	-1.6	-0.4	-0.1	-1.5	-0.7	-0.4	0.1	-0.0
Had menopause	0.1	0.2	0.5	0.1	-0.4	-0.4	-0.7	-0.0	0.2	-0.4	-0.4
Allergy	0.1	0.2	0.6	0.8	0.3	0.2	0.8	-0.0	0.6	0.2	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.5	-0.1	0.1	0.1	-0.5	0.2	-0.7	0.2	0.2
Falls in the last year	0.1	0.1	0.5	0.6	0.0	0.0	0.7	0.2	-0.4	0.0	-0.1
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	0.2	0.1	-0.1	-0.1	-0.1	0.6	0.3	-0.1
Standing height	0.1	0.8	2.1	-1.4	0.1	0.2	-1.3	-0.4	-1.3	0.7	0.4
Pulse wave peak to peak time	0.1	0.1	0.4	-0.3	0.0	0.1	-0.3	-0.0	-0.7	-0.2	0.1
Emphysema/chronic bronchitis	0.1	0.1	0.7	0.3	-0.0	-0.0	-0.1	-0.5	0.8	-0.2	-0.1
Comparative height size at age 10	0.1	0.8	3.7	-1.5	-0.0	-0.1	-0.6	-0.0	-1.9	0.1	0.2
Loneliness, isolation	0.1	0.2	0.9	-0.5	-0.1	-0.6	-0.1	0.0	-1.0	0.1	0.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.4	0.0	0.2	0.2	-0.5	-0.5	0.2	0.0
Medication: Lisinopril	0.1	0.1	0.5	0.4	-0.2	0.0	0.7	0.1	-0.6	0.2	-0.1
Ulcerative Colitis (UC)	0.0	0.0	0.1	-0.1	0.2	-0.1	0.1	-0.3	0.2	0.4	0.2
Blood White Count	0.0	0.4	2.5	0.2	-0.1	-0.3	1.6	0.5	0.1	0.2	0.0
Hair Pigment	0.0	0.2	0.5	0.6	-0.3	0.2	0.7	-0.6	0.7	0.4	0.1
Tanning	0.0	0.2	0.8	0.0	-0.4	-0.6	0.4	-0.9	-0.1	-0.5	-0.5
Medication for hormone replacement therapy	0.0	0.0	0.1	0.1	0.4	0.1	-0.1	0.2	-0.2	0.2	0.1
Medication: Metformin	0.0	0.1	0.4	-0.1	-0.1	0.2	-0.6	0.1	-0.0	0.1	0.0
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.2	0.1	0.2	-0.3	-0.1
Diabetes (self-reported)	0.0	0.1	0.2	0.4	0.0	-0.1	0.3	-0.0	0.5	0.2	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	-0.2	-0.3	-0.2	0.1	-0.0	-0.1	-0.2	-0.4
Myopia	0.0	0.1	0.2	0.4	-0.1	0.2	-0.1	0.2	0.4	0.0	-0.0

Hub : Genes

GCC1

Models

Trait associations