[Hub]/) : Traits : Impedance of leg (right) : ← →

chr11:15,288,270-18,106,069

Best TWAS P=2.2e-12 · Best GWAS P=8.93e-11 conditioned to 0.582

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KCNJ11	0.04	0.03	lasso	3	0.03	2.6e-04	5.9	6.0	1.7e-09	0.93	0.02	0.97	FALSE
2	GTEx	Adipose Subcutaneous	RP1-239B22.5	0.11	0.06	enet	21	0.07	1.5e-06	6.2	-5.5	3.1e-08	-0.80	0.01	0.99	FALSE
3	GTEx	Adrenal Gland	SOX6	0.32	0.17	lasso	5	0.16	1.6e-06	5.7	-6.0	1.8e-09	0.00	0.01	0.98	TRUE
4	GTEx	Esophagus Mucosa	KCNJ11	0.27	0.16	lasso	8	0.22	1.6e-14	-4.2	-5.9	3.6e-09	-0.77	0.30	0.70	FALSE
5	GTEx	Esophagus Mucosa	NCR3LG1	0.38	0.38	enet	39	0.42	3.7e-30	-4.2	-5.5	5.0e-08	-0.72	1.00	0.00	FALSE
6	GTEx	Esophagus Mucosa	RP1-239B22.5	0.28	0.28	enet	47	0.32	2.9e-22	-4.2	-5.5	4.0e-08	-0.74	0.96	0.04	FALSE
7	GTEx	Nerve Tibial	RP1-239B22.5	0.11	0.08	lasso	2	0.08	2.9e-06	-4.0	-5.8	5.5e-09	-0.74	0.02	0.95	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	KCNJ11	0.18	0.07	lasso	6	0.12	7.0e-07	5.9	-6.6	5.0e-11	-0.85	0.01	0.99	FALSE
9	GTEx	Skin Sun Exposed Lower leg	KCNJ11	0.23	0.09	lasso	10	0.12	1.7e-10	6.4	-6.8	1.2e-11	-0.89	0.01	0.99	FALSE
10	GTEx	Skin Sun Exposed Lower leg	NCR3LG1	0.12	0.12	lasso	5	0.13	5.0e-11	-4.5	-5.5	5.0e-08	-0.53	0.97	0.03	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RP1-239B22.5	0.06	0.06	lasso	2	0.07	8.6e-07	-4.5	-6.0	2.2e-09	-0.83	0.02	0.98	FALSE
12	GTEx	Small Intestine Terminal Ileum	OR7E14P	0.29	0.10	enet	19	0.22	1.3e-05	-1.9	-5.1	2.7e-07	-0.49	0.18	0.28	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DKFZp686O24166	0.04	0.00	blup	71	0.02	7.1e-03	-4.3	-5.1	2.7e-07	-0.79	0.01	0.80	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	ABCC8	0.05	0.05	lasso	3	0.04	1.7e-09	5.1	-5.1	2.8e-07	-0.09	0.88	0.12	TRUE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp686O24166	0.05	0.03	blup	71	0.04	1.2e-05	-5.3	-7.0	2.2e-12	-0.81	0.01	0.98	TRUE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DKFZp686O24166	0.03	0.01	blup	72	0.03	2.4e-04	6.3	-6.0	2.5e-09	-0.83	0.01	0.96	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DKFZp686O24166	0.08	0.07	lasso	4	0.05	1.2e-03	-4.6	-5.6	1.6e-08	-0.72	0.03	0.93	FALSE