Best TWAS P=1.68e-12 · Best GWAS P=1.75e-17 conditioned to 0.0101
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | -5.5 | -7.1 | 1.7e-12 | -0.86 | 0.04 | 0.74 | TRUE |
| 1 | GTEx | Cells Transformed fibroblasts | AMPD3 | 0.20 | 0.02 | lasso | 8 | 0.01 | 5.5e-02 | 5.8 | -5.8 | 5.7e-09 | -0.22 | 0.30 | 0.04 | TRUE |
| 5 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | -5.5 | 6.9 | 6.3e-12 | 0.88 | 0.15 | 0.85 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SBF2 | 0.16 | 0.14 | lasso | 4 | 0.14 | 6.8e-11 | -6.0 | 6.6 | 3.5e-11 | 0.39 | 1.00 | 0.00 | FALSE |
| 7 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -5.6 | 6.1 | 1.4e-09 | 0.85 | 0.98 | 0.02 | FALSE |
| 8 | YFS | Blood | SWAP70 | 0.09 | 0.07 | bslmm | 379 | 0.08 | 1.6e-24 | 5.4 | 6.0 | 1.9e-09 | 0.32 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | -5.2 | 5.8 | 8.9e-09 | 0.82 | 0.09 | 0.77 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | 1.8 | -5.7 | 1.5e-08 | -0.59 | 0.03 | 0.70 | FALSE |