TWAS hub - ABCC8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1960	0.0360	1.2e-13	0.084	0.118	0.168	0.143	0.167	2.3e-10	3.9e-14	5.8e-20	5.3e-17	7.0e-20
2	ROSMAP	Brain Pre-frontal Cortex	0.2501	0.0411	0.0e+00	0.144	0.154	0.221	0.204	0.222	5.2e-18	2.4e-19	6.6e-28	1.3e-25	4.8e-28
3	TCGA	Breast Invasive Carcinoma	0.0546	0.0189	1.2e-06	0.050	0.037	0.041	NA	0.044	1.5e-10	3.5e-08	7.8e-09	NA	1.7e-09
4	TCGA	Kidney Renal Clear Cell Carcinoma	0.0596	0.0289	1.0e-02	0.010	0.007	0.005	NA	0.006	2.5e-02	4.5e-02	8.8e-02	NA	6.5e-02
5	TCGA	Brain Lower Grade Glioma	0.1163	0.0385	7.1e-07	0.047	0.071	0.075	NA	0.088	4.2e-06	1.8e-08	6.3e-09	NA	3.2e-10
6	TCGA	Lung Adenocarcinoma	0.0936	0.0410	3.6e-04	0.008	0.047	0.013	NA	0.015	3.9e-02	3.1e-06	9.6e-03	NA	5.7e-03
7	TCGA	Lung Squamous Cell Carcinoma	0.0574	0.0256	3.0e-03	0.004	0.015	0.026	NA	0.012	1.1e-01	6.7e-03	5.3e-04	NA	1.4e-02
8	TCGA	Prostate Adenocarcinoma	0.1001	0.0407	1.8e-04	0.063	0.030	0.048	NA	0.024	3.8e-07	3.5e-04	8.5e-06	NA	1.4e-03
9	TCGA	Testicular Germ Cell Tumors	0.2010	0.0680	5.7e-04	0.077	0.077	0.029	NA	0.057	1.1e-03	1.1e-03	3.4e-02	NA	4.6e-03
10	TCGA	Thyroid Carcinoma	0.3370	0.0620	2.4e-13	0.122	0.168	0.173	NA	0.168	6.6e-12	4.1e-16	1.3e-16	NA	4.3e-16

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Frequency of tiredness / lethargy in last 2 weeks	3.5	5.6	14.3	1.8	0.6	3.7	-0.2	2.4	2.1	1.7	3.8	0.6	3.4
Wheeze or whistling in the chest in last year	3.0	5.3	12.3	0.9	0.6	3.5	-1.3	3.1	2.2	2.2	3.1	2.3	2.0
Mean Putamen Volume	2.8	3.2	7.7	0.5	0.9	-2.4	-0.1	-2.5	-1.3	-1.7	-2.8	-1.0	-2.4
Impedance of arm (left)	2.7	12.6	31.9	-3.9	-2.2	-5.6	-0.2	-4.5	-2.4	-1.5	-5.1	-0.5	-4.3
Depression (Nagel 2018)	2.5	3.7	8.0	-0.4	-1.2	2.2	2.3	2.2	1.2	1.7	2.8	1.2	2.6
Impedance of leg (right)	2.3	11.2	26.4	-3.0	-1.1	-5.1	-1.5	-3.9	-2.9	-2.3	-4.7	-1.4	-4.4
High blood pressure (mother)	2.3	3.2	7.3	-2.7	-1.2	-1.7	-0.5	-1.4	-1.6	-1.8	-2.3	-1.1	-2.5
Exposure to tobacco smoke outside home	2.3	3.1	6.5	2.0	2.5	2.4	-0.8	1.9	1.1	-0.3	2.5	0.3	1.8
Mother’s age at death	2.3	2.9	8.1	-1.9	-2.1	-1.4	0.4	-1.4	-0.7	-2.0	-1.7	-2.8	-1.2
Impedance of whole body	2.3	11.8	29.9	-3.3	-1.6	-5.5	-1.0	-4.2	-2.7	-2.0	-5.0	-0.8	-4.4
Bipolar Disorder or Schizophrenia	2.2	5.3	11.9	2.1	1.9	3.4	-0.0	3.2	-0.3	0.2	3.1	2.1	2.8
Breast Cancer	2.2	5.2	10.8	-1.8	-2.0	-2.0	-0.7	-3.3	-1.1	-2.4	-2.7	-2.6	-3.0
Maternal smoking around birth	2.2	3.2	7.9	1.6	1.6	2.0	0.2	2.0	1.1	1.8	2.0	1.7	2.8
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	5.6	-0.6	-0.9	2.1	1.7	2.2	1.2	0.3	2.3	-0.3	2.4
Qualifications: None of the above	2.2	4.7	15.6	4.0	3.3	2.4	-0.6	2.1	-0.3	-0.4	1.9	-0.8	2.5
Length of working week for main job	2.2	2.4	5.0	0.9	1.2	1.6	-0.7	2.2	0.5	1.8	1.8	2.1	1.5
Whole body water mass	2.2	12.5	22.8	1.3	-0.3	4.8	3.2	4.5	3.7	2.6	4.7	2.6	4.6
Arm predicted mass (left)	2.2	11.1	22.4	1.4	-0.2	4.6	2.6	4.7	3.4	2.2	4.3	2.2	4.2
Impedance of leg (left)	2.1	10.3	23.8	-2.9	-0.9	-4.9	-1.7	-3.7	-2.9	-2.5	-4.5	-1.2	-4.1
Smoking status: Previous	2.1	3.2	10.5	3.2	2.7	0.8	-2.8	-0.3	-0.4	-0.7	1.0	-2.0	0.4
Whole body fat-free mass	2.1	11.8	21.4	1.2	-0.3	4.6	3.2	4.4	3.5	2.5	4.5	2.5	4.5
Schizophrenia (2018)	2.0	4.1	10.6	1.2	1.1	2.6	1.0	3.1	-0.6	0.5	2.9	1.0	3.3
Average weekly fortified wine intake	2.0	2.4	5.8	-0.7	1.5	-2.4	-1.5	-1.1	-1.3	-0.3	-2.0	-1.9	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.0	2.7	7.5	-0.0	-0.5	1.9	1.6	1.5	0.7	1.4	2.6	0.9	2.7
Financial difficulties in last 2 years	2.0	2.7	8.0	-0.2	0.4	1.8	0.7	1.2	2.8	2.5	2.0	-0.9	1.7
Trunk fat-free mass	2.0	11.2	19.3	0.8	-0.4	4.3	3.4	4.4	3.4	2.3	4.3	2.6	4.4
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	5.3	-2.0	-2.3	-1.4	0.6	-1.6	0.5	-0.8	-2.1	-0.4	-1.9
Handedness (chirality/laterality): Left-handed	2.0	2.4	6.5	-0.6	-0.1	-2.3	0.4	-1.6	-1.4	-1.4	-2.6	-1.6	-1.5
Ever had bowel cancer screening	2.0	2.4	5.9	-0.2	-0.6	-1.3	-1.6	-2.4	-0.2	-2.4	-2.1	-0.8	-1.6
Arm fat-free mass (left)	2.0	10.1	19.6	1.2	-0.3	4.4	2.6	4.3	3.3	2.2	4.1	2.3	4.0
Past tobacco smoking	1.9	3.5	11.6	-3.4	-2.9	-0.9	2.7	0.4	0.8	0.8	-1.0	2.1	-0.3
Trunk predicted mass	1.9	10.8	18.7	0.7	-0.3	4.2	3.4	4.3	3.4	2.3	4.2	2.5	4.3
Birth weight	1.9	4.0	12.5	1.2	1.2	1.8	0.8	3.5	1.1	1.6	2.3	1.1	3.3
Mood swings	1.9	3.4	8.5	1.8	0.8	2.7	-0.3	2.4	0.6	1.5	2.9	0.3	2.4
Ulcerative Colitis	1.8	2.6	9.9	2.9	3.1	0.5	-0.7	0.6	-1.3	-1.2	0.1	1.8	-0.1
Leg fat-free mass (left)	1.8	9.6	17.0	1.2	-0.5	4.1	2.7	3.6	3.6	2.8	4.0	2.2	4.0
Leg predicted mass (left)	1.8	9.4	16.6	1.1	-0.6	4.1	2.8	3.5	3.6	2.7	3.9	2.1	4.0
Impedance of arm (right)	1.8	8.2	22.4	-3.4	-1.6	-4.7	0.7	-3.7	-2.0	-1.1	-4.0	0.3	-3.2
Arm fat-free mass (right)	1.8	9.1	20.0	1.5	-0.3	4.5	2.2	4.1	3.0	1.9	4.1	1.5	3.9
Commuting to job workplace: Car/motor vehicle	1.8	2.1	5.6	2.3	1.5	2.4	-0.7	0.9	0.1	-1.2	1.6	0.8	1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.7	8.3	0.9	0.5	2.8	2.5	1.9	0.9	0.2	2.5	1.6	2.9
Leg fat-free mass (right)	1.8	9.7	17.6	1.1	-0.5	4.2	2.7	3.6	3.5	2.5	4.0	2.4	4.1
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	6.7	2.1	2.2	0.2	-2.6	0.1	-0.3	0.5	0.5	-1.6	-0.4
Leg predicted mass (right)	1.8	9.9	17.8	1.1	-0.5	4.2	2.8	3.7	3.5	2.5	4.1	2.5	4.1
Basal metabolic rate	1.8	9.9	18.2	1.1	-0.4	4.3	2.7	3.9	3.5	2.5	4.1	2.2	4.1
Unable to work because of sickness or disability	1.8	2.3	6.6	1.6	0.7	2.6	-1.2	1.0	1.7	0.3	2.0	-1.1	1.6
Irritable Bowel Disease (IBD)	1.7	4.1	11.4	3.4	3.0	1.6	-0.5	1.9	-0.4	0.6	2.1	2.5	1.7
Ulcerative Colitis (UC)	1.7	3.1	9.6	3.1	2.8	1.4	0.4	1.4	-0.2	0.5	1.9	1.9	1.5
Primary Biliary Cirrhosis	1.7	2.4	7.9	2.8	1.4	2.1	0.1	1.6	0.6	0.1	2.0	-0.2	1.8
Schizophrenia (2014)	1.7	3.6	8.6	2.2	1.8	2.9	0.1	2.4	-1.0	0.1	2.7	0.6	2.4
Nervous feelings	1.7	3.2	9.7	1.3	1.5	-0.9	-1.4	-1.1	-3.1	-2.7	-1.0	-1.9	-1.6
Pulse wave reflection index	1.7	2.1	8.3	1.9	1.8	-0.3	-2.9	-0.3	-0.9	-1.4	-0.9	-0.1	-1.4
Arm predicted mass (right)	1.7	8.5	17.7	1.4	-0.4	4.2	2.1	4.0	3.0	1.9	3.9	1.9	3.7
Loneliness, isolation	1.7	2.3	6.4	-0.0	-0.2	1.9	0.9	2.4	0.7	1.6	2.5	0.6	1.8
Irritability	1.7	2.9	7.0	-0.2	-0.4	2.6	2.1	1.8	1.9	0.2	2.1	1.5	2.0
Depressed Affect (Nagel 2018)	1.6	3.5	8.8	0.5	0.0	2.5	0.3	3.0	1.4	1.9	2.9	0.5	2.2
Alzheimer’s Disease (in father)	1.6	1.7	3.9	2.0	1.7	0.9	-2.0	1.5	-0.3	-0.6	1.3	-1.2	0.1
Eye problems/disorders: Diabetes related eye disease	1.6	1.8	4.6	-2.0	-2.1	-0.5	0.6	0.2	1.6	1.8	0.1	1.7	0.0
Chronic bronchitis/emphysema (mother)	1.6	1.8	3.4	0.2	0.8	1.7	-0.7	1.8	1.3	1.5	1.6	1.5	1.3
Alzheimer’s Disease (including proxy)	1.5	2.2	5.6	-0.0	-0.4	2.4	0.8	2.2	1.3	0.4	2.4	-0.0	1.6
Systolic Blood Pressure	1.5	7.8	24.0	-4.9	-2.9	-2.7	3.5	-1.8	-0.0	0.1	-2.9	2.9	-2.3
Pack years adult smoking proportion	1.5	2.3	6.7	1.0	0.8	2.6	0.9	2.2	0.5	-0.5	2.2	0.7	1.7
Current tobacco smoking	1.5	2.5	8.0	0.7	0.1	2.8	0.7	1.1	2.1	1.1	1.9	0.9	2.2
Father’s age at death	1.5	2.0	6.1	-1.2	-1.9	-0.5	2.0	-1.2	0.2	-2.5	-1.0	-1.4	0.7
Breastfed as a baby	1.5	1.9	4.9	-0.6	-1.7	-2.0	0.3	-1.5	-0.0	-1.8	-2.2	0.3	-1.1
Health satisfaction	1.5	1.9	5.1	1.4	0.4	2.1	1.1	2.3	-0.3	0.3	1.8	0.3	1.8
Intelligence (Savage-Jansen 2018)	1.4	4.4	14.3	-1.7	-0.6	-2.8	-0.2	-3.8	-0.9	-1.2	-2.8	-0.9	-2.8
Alcohol intake versus 10 years previously	1.4	2.0	4.6	1.6	1.0	1.6	-0.5	2.1	0.8	1.6	1.9	0.1	1.6
Falls in the last year	1.4	1.8	5.5	1.1	0.4	1.7	0.0	0.9	1.7	1.0	2.3	-0.7	1.9
Mouth/teeth dental problems: Dentures	1.4	2.4	5.2	2.3	2.0	2.0	1.0	1.1	-0.3	-0.2	1.7	-0.5	2.1
Prospective memory result	1.4	1.7	5.9	2.4	1.7	0.6	-2.1	0.6	-1.3	-0.5	0.4	-1.2	0.1
Medication: Gliclazide	1.4	1.5	5.2	-2.3	-2.2	-0.5	1.0	-0.8	1.5	0.2	-0.2	1.1	-0.3
Pack years of smoking	1.4	2.0	4.9	0.9	0.6	2.2	1.3	2.1	0.2	-0.5	2.1	0.8	1.7
Bipolar Disorder (2018)	1.3	2.1	4.9	1.9	1.6	2.2	-1.3	1.3	0.3	-0.3	1.4	2.1	0.4
Age at First Birth	1.3	1.9	4.5	0.5	0.5	-1.6	-0.7	-2.0	-1.2	-1.9	-2.1	0.1	-1.5
Relative age of first facial hair	1.3	2.7	6.3	0.7	-0.3	-1.1	-2.2	-1.5	-0.7	-2.3	-1.3	-2.5	-2.1
Qualifications: CSEs or equivalent	1.3	1.8	3.9	0.7	0.8	2.0	-0.8	1.3	0.8	1.7	1.9	1.2	1.1
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	5.6	-2.4	-1.9	-0.9	0.7	-1.1	1.2	1.4	-0.7	2.0	-1.0
Medication: Amlodipine	1.3	1.8	7.4	-2.0	-1.2	-0.1	2.7	0.4	-1.6	-1.2	-0.6	0.6	0.3
Comparative height size at age 10	1.3	6.9	21.9	-2.8	-2.9	0.4	4.7	2.4	1.7	1.4	1.1	4.0	1.8
Age at last live birth	1.3	1.9	5.0	-1.5	-0.9	-2.2	0.4	-2.2	-0.3	-0.3	-1.7	0.6	-1.5
Financial situation satisfaction	1.3	1.6	3.3	1.8	1.6	1.6	0.7	0.7	0.1	0.8	1.7	-0.2	1.6
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	7.7	-1.5	-1.5	-0.5	-0.2	-1.1	-0.4	-2.8	-1.4	-0.1	-1.2
Verbal and Numeric Reasoning (VNR)	1.2	2.9	8.8	-1.5	0.1	-2.7	0.4	-3.0	-0.6	-0.5	-2.4	-0.6	-1.9
Weight	1.2	5.8	11.8	0.8	-0.3	3.4	1.7	2.9	3.1	2.3	3.0	1.1	3.0
Standing height	1.2	11.9	34.9	-2.0	-2.5	1.8	5.9	3.5	3.0	2.2	2.6	5.0	3.6
Blood clot in the leg (DVT)	1.2	1.5	6.1	-1.6	-1.5	-0.5	0.2	-1.0	-0.5	-2.5	-1.4	0.3	-1.1
Emphysema/chronic bronchitis	1.2	1.4	3.6	-0.4	-1.5	1.1	0.8	0.7	1.9	0.8	1.3	1.6	0.8
Number of full sisters	1.2	1.5	3.7	1.5	1.2	1.2	-1.9	0.7	1.0	1.5	1.3	-0.5	0.9
Overall health rating	1.2	2.6	8.1	1.4	0.5	2.8	0.5	1.1	1.6	0.5	2.3	-0.2	2.4
Crohns Disease (2017)	1.1	2.4	5.3	2.3	2.1	1.1	-1.5	1.8	-0.2	0.8	1.6	2.0	1.1
Hand grip strength (left)	1.1	2.8	8.6	-0.6	-0.1	-2.8	-1.4	-1.6	-0.2	0.1	-2.6	-0.1	-2.9
Multivitamins +/- minerals	1.1	1.4	5.2	0.8	0.5	1.1	-1.1	0.2	1.0	1.3	2.3	-1.4	1.0
Sitting height	1.1	8.0	16.9	-1.2	-1.7	1.6	3.4	2.8	3.8	2.9	2.4	4.1	2.8
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	4.0	-0.0	-0.0	-1.2	-1.2	-1.5	-0.5	-1.2	-2.0	-0.6	-1.6
Ever highly irritable/argumentative for 2 days	1.1	1.3	3.3	1.8	1.8	1.2	0.4	1.4	-0.3	0.2	1.3	-0.2	1.2
Medication: Ibuprofen	1.1	1.3	4.9	1.7	2.2	0.2	-1.9	0.7	-0.3	-0.5	0.9	0.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	4.0	0.7	-0.3	1.2	-0.9	-1.7	1.3	-0.9	0.6	-2.0	-0.1
Illnesses of father: None of the above (group 1)	1.1	1.4	3.4	0.2	1.1	-1.7	-0.4	-1.8	-0.2	-0.7	-1.9	0.5	-1.5
Number of operations (self-reported)	1.1	1.6	4.6	-0.1	-0.1	-2.1	-1.5	-1.8	-0.9	-0.2	-2.0	-0.5	-1.3
Diastolic blood pressure, automated reading	1.1	3.4	7.6	-0.3	-1.1	2.4	1.4	1.8	2.3	1.7	1.9	2.8	1.6
Alzheimer’s Disease (in mother)	1.0	1.2	2.5	-0.5	-0.6	1.6	1.1	1.2	1.4	0.8	1.3	-0.8	1.2
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.8	-1.1	-1.1	-0.1	1.9	0.4	-1.5	-1.7	-0.5	0.5	-0.3
Height	1.0	19.0	64.3	-3.9	-4.7	2.1	8.0	3.4	3.4	1.9	2.7	5.6	4.3
Allergy or Eczema	1.0	2.7	6.6	0.5	0.9	-1.8	-2.6	-1.8	-1.1	-1.0	-1.7	-1.5	-2.3
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	4.5	-0.8	-2.1	0.7	0.9	-0.3	1.6	0.5	1.0	1.2	0.8
Ever had hysterectomy (womb removed)	1.0	1.1	3.3	-0.7	-1.3	-0.0	1.8	0.0	1.2	1.3	0.1	1.0	1.1
Vitamin and mineral supplements	1.0	1.4	6.6	-1.2	-1.0	-0.7	1.5	0.0	-0.1	-0.4	-1.3	2.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	4.8	1.8	2.1	-0.8	-2.0	-0.7	-2.2	-1.3	-1.1	-0.2	-1.6
Diabetes (self-reported)	1.0	1.6	2.8	-1.6	-1.3	0.6	1.2	0.4	1.7	1.4	1.2	1.5	0.8
Medication: Paracetamol	1.0	1.6	5.2	1.8	1.3	0.1	-2.3	-0.6	-0.4	-1.0	-0.2	-2.0	-0.8
Eye problems/disorders: None of the above	1.0	1.1	3.2	1.0	1.8	0.0	-1.3	0.0	-0.4	-1.5	-0.0	-1.7	-0.7
Had major operations	1.0	1.1	3.7	-1.5	-1.9	-1.5	0.7	0.4	0.1	0.6	-0.8	1.2	0.2
Qualifications: nursing, teaching	1.0	1.5	3.3	-1.3	-1.1	-1.0	1.1	-1.8	0.3	-0.7	-1.7	0.1	-1.6
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	4.3	-1.8	-2.1	-1.7	0.5	-0.8	0.6	-1.0	-1.4	0.7	-0.9
Osteoarthritis (self-reported)	1.0	1.3	3.0	1.6	1.0	1.1	0.1	1.2	-1.2	-1.7	0.7	-0.9	0.6
Pain type(s) experienced in last month: Hip pain	1.0	1.3	4.1	1.6	1.0	1.5	-2.0	1.1	0.5	0.1	1.2	-0.2	0.3
Medication: Bendroflumethiazide	1.0	1.5	6.4	-2.5	-1.9	-0.5	1.9	-0.4	0.3	-0.1	-0.7	-0.1	0.0
Illnesses of father: High blood pressure	1.0	1.2	2.8	-1.7	-1.7	0.4	0.9	0.0	1.2	0.9	0.8	1.5	0.8
Ovarian Cancer	0.9	1.1	2.7	-1.0	-1.2	1.2	0.6	0.9	1.6	1.1	1.1	0.3	1.0
Crohns Disease (2012)	0.9	1.4	3.8	1.4	1.5	-0.8	-1.8	-0.1	-1.1	-0.1	-0.5	2.0	-0.5
Type 2 Diabetes (T2D) (2018)	0.9	1.7	4.0	-1.4	-1.2	1.1	0.5	0.4	1.3	2.0	1.6	1.8	0.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	3.6	0.0	0.0	-1.0	-1.6	-1.6	-0.5	0.0	-0.9	-1.9	-0.9
Medication for hormone replacement therapy	0.9	1.0	2.2	-1.0	-0.9	-1.0	-0.2	-1.5	-1.4	-1.0	-0.9	-0.4	-0.7
Townsend deprivation index at recruitment	0.9	1.2	3.8	2.0	1.4	1.3	-0.2	0.4	-0.2	0.2	1.4	-0.8	1.3
Hair/balding pattern: Pattern 2	0.9	1.1	6.0	-1.4	-1.2	-0.2	0.9	0.7	-0.7	0.7	0.3	2.4	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	5.9	1.2	1.1	-1.2	-1.1	-1.3	-2.4	-1.5	-1.4	-0.1	-1.6
Worrier / anxious feelings	0.9	1.7	4.0	-1.4	-0.5	-1.1	-0.2	-1.8	-1.5	-1.1	-1.2	-2.0	-1.1
Happiness	0.9	1.1	4.4	-0.1	0.1	0.0	2.1	1.1	-1.5	-1.5	-0.2	-0.9	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.7	1.6	1.9	0.1	-1.7	0.5	-0.7	-0.6	0.8	-0.2	0.3
Tense / ‘highly strung’	0.9	1.4	3.0	1.5	1.7	1.6	-0.2	1.4	-0.1	0.0	1.6	-0.1	1.4
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	7.9	1.4	1.1	0.9	-2.8	0.7	-1.1	-1.0	0.8	-0.3	-0.0
Pulse wave peak to peak time	0.9	1.1	3.0	-1.1	-1.3	0.2	1.7	0.8	1.0	1.4	0.8	0.6	0.7
Medication for pain relief, constipation, heartburn	0.9	1.6	5.8	-2.4	-1.3	-1.0	1.9	-0.5	0.7	0.9	-1.2	0.9	-0.4
Medication: Blood pressure	0.9	1.7	11.3	-0.9	-0.8	0.4	3.4	0.4	0.8	0.6	-0.0	1.3	1.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.0	2.1	-1.4	-1.1	-1.1	1.4	-0.1	-0.4	-0.5	-1.4	1.3	-0.2
Long-standing illness, disability or infirmity	0.9	1.3	4.5	1.4	0.2	2.1	-0.6	0.1	0.5	-0.8	1.7	0.9	1.2
Medication: Paracetamol	0.9	1.5	4.9	1.1	0.8	-0.5	-2.2	-0.7	-0.6	-1.2	-0.7	-1.7	-1.4
Ever smoked	0.9	1.5	6.0	2.4	1.9	0.8	-1.2	-0.5	-0.3	-1.0	0.8	-1.1	0.3
Age started oral contraceptive pill	0.9	1.1	2.5	-1.5	-1.6	-1.4	1.1	-0.9	0.9	-0.5	-1.1	0.1	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	4.6	-0.7	-2.1	-0.9	0.2	-1.1	-0.6	-1.5	-0.7	-0.9	-0.3
HbA1C	0.8	0.8	2.3	-0.6	-0.6	1.1	-0.5	0.7	0.4	1.5	1.1	-1.4	0.3
Chronotype (morning person)	0.8	1.7	7.2	0.9	2.1	-1.3	-1.6	0.2	-2.7	0.3	-0.4	0.6	-0.3
Average weekly spirits intake	0.8	0.9	2.8	0.4	0.4	1.4	0.6	1.7	-0.6	0.6	0.8	1.4	0.8
Supplements: Zinc	0.8	0.8	2.5	0.1	0.0	-1.5	1.0	-1.0	-1.6	-0.8	-0.8	-0.3	-0.7
Hearing difficulty/problems with background noise	0.8	1.2	2.9	1.7	1.4	0.8	-1.5	0.8	0.4	0.9	1.5	0.9	-0.3
Had other major operations	0.8	1.0	4.3	-0.4	-0.6	0.4	-0.8	0.6	1.8	2.1	0.9	-0.1	0.5
Pain all over the body in last month	0.8	0.9	3.1	0.5	-0.1	1.8	-0.6	-0.8	1.1	-0.3	1.4	-1.0	0.1
Fluid intelligence score	0.8	1.8	4.5	-2.1	-0.3	-1.7	1.1	-1.9	0.3	-0.3	-1.7	0.3	-1.4
Qualifications: A levels/AS levels or equivalent	0.8	1.8	4.4	-2.1	-1.9	-1.3	1.1	-1.8	0.6	0.7	-1.3	0.1	-1.2
Lung cancer (father)	0.8	0.9	2.0	0.8	0.6	0.4	-1.3	-1.4	-0.7	-1.1	-0.2	-1.1	-1.1
Pulse wave Arterial Stiffness index	0.8	0.9	2.4	1.0	1.3	-0.1	-1.6	-0.6	-1.0	-1.2	-0.7	-0.4	-0.6
Exposure to tobacco smoke at home	0.8	0.9	5.1	1.1	2.2	0.2	-1.3	0.1	-0.5	-0.0	0.1	-0.9	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	5.6	-0.9	0.1	-0.5	-0.6	-1.8	-0.2	-0.7	-0.7	-2.4	-0.7
Qualifications: College or University degree	0.8	2.5	7.8	-2.8	-2.3	-1.1	2.5	-1.1	1.0	-0.3	-0.9	-0.4	-0.6
Medication: Omeprazole	0.8	0.9	2.4	-0.5	-1.5	-0.9	0.7	-0.6	-1.2	-1.6	-0.6	-0.9	-0.2
Heart disease (mother)	0.8	0.9	1.9	0.6	-0.5	1.3	1.4	1.2	0.8	0.2	0.5	1.3	1.1
Chest pain or discomfort	0.8	1.2	3.2	1.2	1.8	1.0	-1.2	1.4	0.2	0.9	0.9	-0.2	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	2.0	-0.6	-0.9	1.0	-0.2	-0.0	0.9	1.4	1.3	1.2	0.9
Hypertension (Self-reported)	0.8	2.1	7.6	-2.6	-1.9	0.3	2.8	-0.1	1.5	0.1	-0.5	1.0	0.2
Diabetes diagnosed by doctor	0.8	1.4	3.1	-1.7	-1.6	0.8	0.9	0.3	1.4	1.2	1.3	0.9	0.8
Medication: Aspirin	0.8	1.1	2.4	0.6	0.5	1.1	-0.5	1.6	0.5	1.4	1.3	1.4	0.8
Smoking status: Current	0.8	1.3	4.5	0.4	0.0	2.1	0.5	0.6	1.6	0.9	1.4	0.5	1.5
Guilty feelings	0.8	1.2	2.9	0.5	1.4	-1.3	-1.4	-0.6	-1.4	0.6	-0.2	-1.7	-0.4
Medication: Atorvastatin	0.8	0.9	2.7	-0.8	-0.5	-1.3	-0.2	-1.1	-0.4	0.0	-1.4	-1.6	-1.0
Supplements: Calcium	0.8	0.9	2.5	-1.6	-1.0	-1.4	0.4	-0.5	1.0	1.1	-0.8	0.4	-0.4
Alcohol drinker status: Previous	0.8	0.9	4.8	0.0	-0.6	0.8	-0.6	0.0	-1.0	-2.2	0.0	-1.1	0.8
Body Mass Index (BMI) (2010)	0.7	0.9	2.0	1.2	0.4	1.4	0.1	1.2	0.4	-0.0	1.2	-1.0	1.3
Neuroticism (2016)	0.7	0.9	5.7	-0.5	-0.5	-0.3	-0.9	-0.9	-0.9	-0.2	-0.3	-2.4	-0.7
Heel T-Score	0.7	5.5	17.1	-0.1	0.6	-2.5	-2.2	-2.2	-2.1	-2.7	-3.1	-0.5	-4.1
Systolic blood pressure, automated reading	0.7	2.0	6.9	-1.8	-1.7	0.1	2.4	0.1	0.9	-0.1	-0.8	2.6	-0.4
Age when periods started (menarche)	0.7	1.8	4.4	2.1	2.0	1.3	0.4	1.2	0.1	-1.1	1.0	1.0	1.6
High blood pressure	0.7	2.0	6.9	-2.6	-1.6	-0.0	2.6	-0.2	1.2	0.1	-0.8	1.4	0.1
Stomach or abdominal pain in last month	0.7	0.9	2.4	-0.2	-1.6	0.3	1.2	-0.4	1.3	1.1	0.7	0.6	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	3.5	0.3	-0.3	1.8	0.6	0.6	-0.4	-0.5	1.9	-1.1	1.3
Had menopause	0.7	0.8	2.5	-1.0	-1.6	-0.8	-0.1	-0.6	-0.3	-0.9	-1.0	-1.2	-0.6
Time employed in main current job	0.7	0.8	4.2	-0.9	-2.1	-0.4	0.5	-1.1	0.2	1.0	-0.4	0.5	0.4
Depression (self-reported)	0.7	0.9	2.1	1.5	1.0	0.8	-1.2	0.4	0.1	-0.1	1.2	-1.2	0.3
Age at first live birth	0.7	1.3	2.6	-1.6	-1.0	-1.6	0.5	-1.1	-0.1	-0.7	-1.0	1.6	-1.0
Pulse rate, automated reading	0.7	2.1	9.3	-2.7	-3.0	-0.4	1.2	-1.2	0.9	0.3	-0.8	0.6	-0.1
Supplements: Vitamin C	0.7	0.8	2.2	1.5	1.2	-0.1	-0.7	-0.7	-0.8	-1.1	-0.6	-0.6	-1.1
Wears glasses or contact lenses	0.7	0.8	1.8	-1.4	-1.0	-1.1	1.2	-0.6	-0.8	0.0	-0.9	-1.0	0.2
Commuting to job workplace: Public transport	0.7	0.8	2.7	-0.5	-0.1	-1.5	-0.5	-1.0	0.4	-0.0	-1.7	-0.7	-1.1
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.1	-1.4	-1.1	0.1	0.6	-0.5	1.4	1.3	-0.0	-0.3	0.3
Fractured/broken bones in last 5 years	0.7	0.9	2.0	0.5	0.2	1.4	-0.2	0.9	1.1	-0.2	1.4	-1.2	1.2
Major Depression (MDD)	0.6	0.8	2.1	0.6	-0.4	1.3	1.5	0.4	0.5	0.2	1.0	-0.5	1.4
Bipolar Disorder (2011)	0.6	0.6	2.1	-0.1	0.3	-0.2	-0.2	1.0	-1.3	-1.4	-0.4	0.6	-0.2
Neuroticism	0.6	1.3	3.4	0.3	0.3	1.8	0.7	1.8	0.3	-0.2	1.6	-0.4	1.8
Medication: Co-codamol	0.6	0.6	2.0	1.4	0.5	0.7	-0.3	-0.8	-0.2	-0.5	0.3	-1.3	0.9
Medication: Metformin	0.6	0.8	3.1	-1.2	-1.3	0.3	1.0	0.0	0.5	0.1	0.5	1.8	-0.1
Serious illness, injury or assault to yourself	0.6	0.7	3.6	0.4	-1.0	0.1	1.9	-0.6	-0.0	1.0	0.5	0.3	0.6
Chronic bronchitis/emphysema (father)	0.6	0.7	1.9	1.3	0.2	1.4	-0.7	0.3	0.3	-0.5	1.1	-0.4	0.8
Body mass index (BMI)	0.6	2.6	7.7	1.9	1.0	2.8	-1.0	1.4	1.7	1.1	1.9	-1.3	1.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	2.5	0.4	1.3	0.3	-0.9	0.1	-1.6	-0.9	0.2	-1.1	0.2
Hip circumference	0.6	2.5	6.5	1.1	0.3	2.5	0.9	1.9	1.8	1.3	1.9	-0.0	2.1
Noisy workplace	0.6	0.7	1.6	0.7	0.8	-0.1	0.1	0.9	-0.8	1.2	0.5	1.0	1.3
Loud music exposure frequency	0.6	0.6	1.9	-1.2	-0.6	-0.7	-1.4	-0.1	0.5	0.6	0.0	-1.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	3.1	-1.4	-1.8	-0.1	0.6	-1.1	0.5	0.0	0.1	-0.6	-0.1
Alcohol intake frequency.	0.6	1.5	3.0	1.7	1.0	1.4	-0.5	1.1	0.4	1.5	1.6	-0.1	1.6
Suffer from ‘nerves’	0.6	0.9	4.0	0.7	2.0	0.3	-1.4	0.3	-0.9	0.6	0.6	-1.1	-0.0
Illnesses of father: Heart disease	0.6	0.8	3.6	-0.3	-1.3	0.1	-0.5	0.2	-0.0	1.4	0.4	-1.9	-0.4
Eye problems/disorders: Cataract	0.6	0.7	2.3	-0.6	-1.5	0.3	1.2	1.0	0.2	-0.3	0.0	1.3	0.4
Back pain experienced in last month	0.6	0.9	2.2	1.4	1.5	-0.6	-1.2	-0.9	-0.3	0.3	-0.5	-1.0	-0.7
Average weekly champagne plus white wine intake	0.6	0.8	3.3	1.1	1.5	-0.1	-0.5	-0.7	-0.9	-0.3	-0.3	-1.8	-0.2
Ever taken oral contraceptive pill	0.6	0.7	1.8	-1.3	-0.4	-1.3	-0.8	-0.7	-0.1	-0.1	-1.0	-0.7	-0.7
Hearing aid user	0.6	0.6	1.8	1.1	1.3	0.1	-1.0	-0.5	-0.4	-0.0	-0.3	-0.4	-1.3
Medication: Lisinopril	0.6	0.8	3.2	-0.1	-0.0	0.4	1.3	0.1	0.8	1.0	0.3	1.8	0.9
Cholesterol lowering medication	0.6	0.9	1.7	-1.3	-1.1	-0.6	-0.3	-0.7	1.1	1.3	-0.4	0.8	-1.2
Heart disease (siblings)	0.6	0.7	2.1	1.3	1.2	0.3	-1.4	0.1	0.3	0.3	0.3	-1.3	0.0
Coronary Artery Disease (CAD)	0.5	0.6	2.4	-0.7	-0.2	0.0	1.2	-0.2	-1.2	-1.5	-0.3	-0.7	0.3
HDL Cholesterol	0.5	0.9	2.6	-0.6	-0.4	1.1	1.6	1.4	0.1	-0.1	0.6	1.2	1.0
LDL Cholesterol	0.5	0.7	2.7	-0.5	-0.9	0.7	0.6	0.2	1.7	0.2	1.3	0.8	0.6
Rheumatoid Arthritis	0.5	0.7	2.4	-1.2	-1.5	0.1	1.4	-0.1	0.6	0.6	0.2	-0.5	0.5
Smoking Status	0.5	1.2	2.6	1.4	1.2	1.6	-1.1	-0.2	1.0	0.7	0.8	-1.6	0.7
Respiratory disease	0.5	1.1	6.4	0.3	-0.2	0.0	-2.5	-0.8	0.6	1.1	0.3	0.8	-1.1
Frequency of depressed mood in last 2 weeks	0.5	0.8	3.1	0.1	-0.9	1.0	0.5	1.0	0.2	0.5	1.8	0.3	1.1
Hearing difficulty/problems: Yes	0.5	0.8	2.3	0.2	0.3	0.3	-0.3	1.4	1.1	1.3	0.6	1.5	-0.5
Diabetes (mother)	0.5	0.6	1.7	-1.3	-0.8	-0.7	1.3	-0.7	0.3	-0.0	-0.8	0.3	-0.8
Fed-up feelings	0.5	0.9	2.4	-0.1	0.0	1.0	0.1	1.4	-0.1	0.7	1.6	-0.8	1.5
Relative age voice broke	0.5	0.7	3.9	-0.3	-0.6	0.1	-1.0	0.1	1.1	-0.7	-0.3	-2.0	-0.6
Taking other prescription medications	0.5	0.8	2.8	0.6	-0.4	0.5	-0.3	0.1	1.5	1.7	0.9	0.4	1.1
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.8	-0.5	-0.0	-1.6	-1.6	-1.2	-0.5	0.1	-1.1	-0.4	-1.7
Medication: Atenolol	0.5	0.6	2.7	-0.3	0.1	-0.0	1.6	0.8	0.0	0.3	0.2	1.2	1.0
Waist circumference	0.5	1.7	3.7	0.2	-0.0	1.9	0.8	1.1	1.7	1.7	1.6	0.4	1.6
Number of incorrect matches in round	0.5	0.8	2.8	1.2	1.4	0.5	0.4	0.4	-0.8	-0.4	-0.2	1.7	0.1
Alcohol usually taken with meals	0.5	0.8	3.2	-0.3	-0.5	-1.8	-0.8	-0.5	-0.5	0.1	-0.9	-1.2	-0.7
Mouth/teeth dental problems	0.5	0.8	2.3	-0.2	0.0	-0.6	-0.9	-1.4	0.4	1.0	-0.8	-0.7	-1.5
Illnesses of siblings	0.5	0.6	1.6	-1.3	-1.1	0.3	0.1	1.2	-0.1	0.5	0.9	0.8	0.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	3.5	-1.9	-1.6	-1.2	-0.7	-0.2	1.6	0.5	-1.1	1.1	-1.5
Arm fat mass (right)	0.5	2.0	5.8	1.0	0.2	2.4	0.4	1.3	1.9	1.3	1.7	-0.4	1.6
Headache pain in last month	0.5	0.9	2.5	-1.2	-1.2	-1.2	-1.6	-0.9	-0.2	0.8	-0.2	0.0	-0.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	3.1	0.3	0.1	0.1	-1.7	0.2	0.0	0.6	0.2	-1.8	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.2	1.0	0.6	-0.5	-0.4	-0.4	-1.5	-1.1	-0.4	0.3	-0.8
Average weekly red wine intake	0.5	0.7	3.6	-1.4	-1.9	-0.1	0.1	0.2	1.0	-0.3	0.0	-0.8	0.2
Commuting to job workplace: Walk	0.5	0.5	1.9	0.4	0.3	-0.3	-0.9	-0.4	-0.2	-0.5	-0.8	-1.4	-1.0
Asthma (self-reported)	0.5	1.1	6.7	-0.6	-0.5	0.0	-2.6	-0.1	0.5	1.2	0.0	0.5	-1.2
High cholesterol (Self-reported)	0.5	0.9	2.2	-0.3	-0.1	-1.3	-0.7	-1.5	0.1	-0.1	-1.5	-0.3	-1.4
Vascular/heart problems diagnosed by doctor	0.5	1.4	7.4	1.7	1.2	-0.4	-2.7	0.0	-1.0	0.2	0.5	-1.1	-0.3
Neuroticism (Nagel 2018)	0.4	0.9	2.6	0.1	0.6	1.3	0.5	1.4	0.0	0.5	1.6	0.3	1.5
Schizophrenia vs Biploar Disorder	0.4	0.5	2.0	0.3	0.5	0.5	1.0	0.5	0.1	0.5	0.9	-0.1	1.4
Lupus	0.4	0.6	1.3	0.6	-0.3	0.7	0.6	-1.0	0.8	-0.7	-0.2	1.0	-1.1
Blood Eosinophil Count	0.4	2.9	10.7	-3.3	-2.8	-0.9	-0.1	-1.0	1.2	0.6	-1.0	-2.2	-0.9
Blood Red Count	0.4	3.4	6.0	-1.8	-2.1	-2.0	-1.8	-2.0	0.5	0.2	-2.3	-2.5	-1.8
Diabetes (father)	0.4	0.5	3.5	-0.1	0.4	0.1	0.6	0.4	-1.9	-0.9	0.1	0.6	-0.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	3.9	-0.2	-0.2	0.3	-2.0	-0.1	0.4	-0.0	0.4	-0.1	-0.5
Medication: Levothyroxine sodium	0.4	0.7	2.1	0.6	-0.1	0.6	-1.4	0.7	1.0	1.2	0.8	-0.5	-0.3
Forced vital capacity (FVC)	0.4	1.4	3.5	-1.7	-1.1	-1.1	-0.9	0.1	1.9	0.6	-1.0	1.4	-1.2
Heart attack	0.4	0.5	2.8	1.7	0.4	0.5	-0.7	-0.2	0.4	0.7	0.4	0.5	-0.3
Neuroticism score	0.4	0.8	1.9	0.7	1.1	0.7	-0.4	0.6	-1.1	-0.6	0.9	-1.4	0.8
Pulse rate	0.4	0.7	3.1	-0.8	-0.8	0.2	0.6	-1.3	0.7	0.0	-0.2	-1.8	-0.2
Asthma	0.4	0.8	5.2	-0.6	-0.6	0.3	-2.3	0.1	0.3	0.8	0.2	0.5	-1.0
Illnesses of mother	0.4	0.5	1.7	1.1	0.9	-0.1	-1.3	-0.5	0.0	0.7	0.6	0.0	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.4	-1.4	-1.0	-1.3	0.1	0.0	1.3	1.1	-0.8	1.6	-1.0
Birth weight of first child	0.4	0.7	1.9	-1.0	-0.2	-0.3	0.5	1.0	1.1	1.4	0.1	-0.1	1.1
Peak expiratory flow (PEF)	0.4	0.8	3.3	0.0	-0.8	-0.3	-1.0	-0.2	1.8	0.2	-0.3	0.3	-1.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	-1.1	-1.0	-0.5	0.1	0.5	-1.0	-0.7	-0.2	0.6	-0.2
Glaucoma (self-reported)	0.4	0.5	1.1	-0.3	-0.8	0.5	1.0	0.6	0.8	0.4	0.6	1.0	0.7
Comparative body size at age 10	0.4	1.1	3.5	-1.3	-1.9	-0.2	0.8	-1.1	0.6	-0.2	-0.8	-1.5	-0.5
Number of full brothers	0.4	0.5	1.7	-0.2	-1.3	0.4	0.1	0.2	0.5	1.0	1.0	-0.4	0.6
Number of children fathered	0.4	0.5	1.7	1.3	1.1	0.3	-0.8	0.4	0.2	0.4	0.6	0.1	-0.0
Medication: Seretide 50 evohaler	0.4	0.5	1.4	0.7	-0.3	0.3	-1.2	-0.2	1.1	0.1	-0.2	-0.7	-0.7
Mean time to correctly identify matches	0.4	0.8	2.3	0.8	0.9	-0.0	0.1	-0.8	-1.5	-1.5	-0.2	-1.3	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.9	0.1	-0.1	-0.9	-0.7	-0.6	-0.1	-0.1	-0.9	-1.4	-0.9
Medication: Aspirin	0.4	0.6	1.2	0.5	0.3	0.7	-0.3	1.1	0.2	1.1	1.0	1.1	0.5
Knee pain experienced in last month	0.4	0.6	2.7	0.3	0.2	0.3	0.1	0.6	-1.3	-0.4	0.5	-1.0	1.6
Illnesses of siblings: Diabetes	0.4	0.5	3.2	-0.3	-0.1	-0.7	1.8	-1.0	0.4	0.4	-0.0	0.2	-0.1
Breast cancer (self-reported)	0.4	0.5	1.7	1.3	0.5	0.9	0.7	0.8	0.3	-1.0	-0.1	0.1	0.0
Osteoporosis (self-reported)	0.4	0.5	1.4	-0.7	-0.5	0.0	0.4	0.8	0.9	1.0	0.2	1.2	0.5
Medication: Blood pressure	0.4	0.7	1.8	-0.8	-0.3	-1.2	-0.2	-1.0	-0.9	-0.5	-1.3	-0.2	-0.9
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	-0.2	-0.1	-0.3	-0.2	-1.2	-0.5	-0.9	-0.3	-1.4	-0.5
Risk taking	0.4	0.6	1.7	0.7	0.7	1.3	-0.0	1.0	0.1	0.2	1.2	0.3	0.7
Pain experienced in last month	0.4	0.6	2.3	-1.0	-0.4	-0.6	1.5	0.6	0.2	0.2	-0.5	1.1	-0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.7	1.6	0.4	0.6	-0.9	-0.2	0.6	0.7	0.5	0.4	-0.3
Worry (Nagel 2018)	0.3	0.5	1.9	-0.2	0.9	-0.2	0.0	-0.3	-1.4	-1.3	-0.3	-0.7	-0.3
Prostate Cancer	0.3	0.4	1.1	0.8	1.0	-0.1	-0.8	0.2	0.8	-0.0	-0.3	0.7	-0.3
BMI	0.3	1.7	4.6	1.4	0.2	2.1	-1.9	0.6	1.4	0.4	1.2	-1.8	0.7
Waist Hip Ratio (WHR)	0.3	1.4	3.7	-1.9	-0.5	-1.7	0.8	-1.1	-0.1	1.3	-0.7	1.4	-0.8
Cardiovascular Disease	0.3	1.0	3.1	-1.8	-1.6	-0.0	1.5	-0.3	0.6	0.1	-0.4	1.2	-0.3
Hypothyroidism (self reported)	0.3	0.8	2.4	-0.2	-0.7	0.3	-0.1	1.6	0.9	1.3	1.2	0.3	1.0
Lung FEV1/FVC ratio	0.3	1.4	6.9	-1.1	-2.6	0.6	1.3	0.3	0.9	0.1	0.5	-1.3	0.9
Sensitivity / hurt feelings	0.3	0.5	1.9	-0.0	0.6	0.7	0.3	0.6	-0.1	0.2	1.1	0.6	1.4
Angina	0.3	0.4	1.0	1.0	0.4	0.8	0.7	0.1	0.6	-0.2	0.2	-0.6	0.6
Severe depression (siblings)	0.3	0.4	0.9	0.7	0.9	-1.0	-0.1	-0.5	-0.9	0.0	-0.5	0.1	-0.2
Hand grip strength (right)	0.3	0.9	3.7	-0.3	-0.7	-1.3	-1.3	-0.7	0.1	0.4	-1.0	0.1	-1.9
Allergy	0.3	0.6	2.9	0.5	0.6	0.5	1.7	0.2	-0.1	0.3	0.6	-0.5	1.3
Medication: Ramipril	0.3	0.4	1.7	-0.1	0.1	0.2	1.3	0.3	-0.3	0.5	0.5	1.0	0.6
Medication: Simvastatin	0.3	0.4	2.3	0.2	0.2	0.2	-0.0	-0.3	1.5	0.7	-0.0	0.7	-0.5
Number of live births	0.3	0.4	2.2	-0.4	-1.5	0.5	0.3	0.1	1.2	0.2	0.1	0.3	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.6	0.9	0.7	0.1	-0.3	-0.5	0.4	0.2	0.1	-1.3	0.2
Medication: Lansoprazole	0.3	0.4	1.5	0.2	0.7	-0.1	-1.2	-0.3	-0.3	1.1	-0.4	0.4	-0.4
Hair/balding pattern: Pattern 4	0.3	0.8	2.0	1.3	1.4	0.0	0.4	1.2	-1.1	0.2	0.2	-0.7	1.0
Forced vital capacity (FVC), Best measure	0.3	1.0	3.3	-1.1	-0.4	-1.2	0.2	0.2	1.4	0.9	-0.8	1.8	-0.7
Worry too long after embarrassment	0.3	0.5	1.9	-0.1	0.7	-0.7	-0.7	-1.4	-1.0	-0.2	-0.5	-0.4	-0.8
Shortness of breath walking on level ground	0.3	0.3	0.7	0.7	0.7	0.8	-0.5	0.5	-0.8	-0.2	0.6	0.2	0.3
Migraine (self-reported)	0.3	0.4	1.6	-1.1	-1.3	0.0	0.3	-0.3	0.7	-0.3	-0.6	-0.3	-0.1
Family relationship satisfaction	0.3	0.4	1.1	0.8	0.1	0.7	0.2	1.0	-0.5	0.7	0.5	-0.5	0.3
Mineral and other dietary supplements	0.3	0.4	1.8	0.2	0.4	0.0	-1.3	0.7	0.1	-0.4	-0.5	0.8	-0.7
Arm fat mass (left)	0.3	1.1	3.3	0.6	-0.1	1.8	0.2	0.7	1.6	1.0	1.1	-0.8	1.0
Number of self-reported non-cancer illnesses	0.3	0.5	1.5	-0.0	-0.6	1.1	0.5	-0.6	1.0	-1.2	0.1	0.9	0.0
Miserableness	0.3	0.6	2.6	0.3	0.2	0.7	-1.2	0.4	0.5	0.4	0.7	-1.6	0.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.0	0.1	0.6	-0.2	0.0	1.0	-0.9	-0.8	-0.4	0.6	0.5
Leg fat percentage (left)	0.3	0.9	4.3	0.8	0.7	0.3	-1.5	-0.7	0.2	-0.3	-0.5	-2.1	-0.7
Commuting to job workplace: Cycle	0.3	0.3	1.2	-1.1	-0.5	0.2	-0.8	0.6	0.2	0.5	0.5	-0.5	-0.4
Myopia	0.3	0.5	1.3	0.5	1.2	-0.1	-1.1	-0.4	-0.2	-0.5	-0.1	-1.1	-0.0
Basal cell carcinoma (self-reported)	0.3	0.4	1.4	0.5	0.4	-1.2	-0.3	-0.4	-0.3	-0.6	-0.9	-0.3	-0.7
Leg fat mass (left)	0.3	1.1	3.0	1.1	0.4	1.7	-0.2	0.9	1.4	0.9	1.1	-1.0	0.9
Triglycerides	0.2	0.3	1.0	0.6	0.1	-0.4	-0.3	-0.9	0.0	-0.3	-0.4	-1.0	-0.8
Blood Platelet Count	0.2	2.3	6.2	1.1	1.5	-1.1	-2.5	-1.2	-1.8	-1.0	-0.8	-2.1	-0.9
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.6	0.4	0.6	-0.4	0.5	-0.7	-0.5	-0.5	-0.6	0.6	-0.2
Supplements: Glucosamine	0.2	0.3	1.0	-0.2	-0.0	-0.7	0.4	-1.0	-0.2	0.6	-0.1	-0.9	-0.1
Trunk fat mass	0.2	0.9	2.2	-0.0	-0.8	1.5	1.1	0.5	1.5	0.7	0.9	-0.3	1.2
Hair/balding pattern: Pattern 3	0.2	0.3	1.7	-0.4	-0.6	0.4	0.3	0.1	0.7	-0.3	0.2	-1.3	0.2
Medication: Cholesterol lowering	0.2	0.4	1.0	0.0	-0.2	-0.4	0.9	-0.7	0.8	1.0	-0.4	-0.3	-0.3
Gout (self-reported)	0.2	0.3	1.2	0.0	-0.5	0.0	-0.6	0.0	0.5	0.6	-0.0	1.1	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.2	-0.6	-1.0	-0.6	-0.7	0.2	0.5	1.1	0.2	-0.7	-0.1
High blood pressure (siblings)	0.2	0.3	0.9	1.0	0.7	-0.4	-0.5	-0.6	-0.4	0.2	-0.8	-0.1	-0.4
Leg fat percentage (right)	0.2	0.9	4.5	0.4	0.3	-0.1	-1.2	-0.9	0.2	-0.2	-0.9	-2.1	-1.0
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.1	0.7	1.0	-0.3	-0.4	0.0	-0.3	0.2	0.2	0.0	-0.3
Angina (self-reported)	0.2	0.3	1.0	1.0	0.5	0.8	0.5	-0.0	0.5	-0.2	0.2	-0.5	0.4
Whole body fat mass	0.2	0.9	2.3	0.4	-0.3	1.5	0.6	0.5	1.4	0.9	0.9	-0.7	1.1
Leg fat mass (right)	0.2	0.9	2.4	1.0	0.2	1.6	0.0	0.6	1.4	0.9	0.9	-1.1	0.8
Leg pain on walking	0.2	0.3	0.5	0.5	-0.3	0.7	0.1	0.2	0.4	-0.7	0.6	-0.7	0.6
Friendships satisfaction	0.2	0.3	0.7	-0.8	-0.7	0.1	0.8	0.2	-0.0	0.0	-0.4	-0.7	-0.4
Medication for cholesterol	0.2	0.3	0.8	0.7	0.6	0.5	-0.3	0.9	0.3	-0.8	-0.0	-0.5	-0.2
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.2	-0.8	-0.5	0.4	-0.5	-0.2	0.2	-0.6	-0.1	-0.2
Alcohol drinker status: Never	0.2	0.2	0.9	-0.3	-0.9	-0.2	0.3	-0.2	0.7	0.7	-0.2	-0.4	-0.4
Average weekly beer plus cider intake	0.2	0.3	1.2	0.5	1.1	-0.8	0.0	-0.4	-0.0	0.8	0.3	0.3	-0.4
Ever depressed for a whole week	0.2	0.3	0.9	0.3	1.0	-0.1	-0.9	-0.3	-0.3	-0.3	-0.1	-0.7	-0.3
Reaction Time	0.1	0.3	0.5	0.6	0.7	0.7	0.4	-0.3	-0.4	-0.6	0.6	-0.5	-0.1
Fasting Glucose	0.1	0.1	0.9	-0.3	0.3	-0.0	-0.4	-0.2	-0.9	-0.2	0.2	-0.3	0.3
Blood White Count	0.1	0.8	1.8	-1.3	-1.1	-1.3	-0.7	-0.7	-0.6	-0.0	-0.8	-1.0	-0.7
Lung FVC	0.1	0.7	1.7	-0.3	-0.4	-1.0	-0.9	-0.8	0.6	-0.8	-1.3	-1.2	-0.7
Hair Pigment	0.1	3.5	9.1	2.1	3.0	0.1	-2.7	2.3	-3.0	-0.4	0.3	0.6	-0.1
Tanning	0.1	1.1	5.4	-0.2	-0.2	1.1	0.6	0.4	2.3	0.7	1.0	-0.4	1.5
Number of treatments/medications taken	0.1	0.2	0.6	-0.3	-0.5	-0.7	0.5	-0.8	-0.1	-0.2	-0.4	0.4	-0.1
Trunk fat percentage	0.1	0.2	0.8	-0.2	-0.7	0.3	-0.0	-0.8	0.5	0.1	-0.4	-0.9	-0.1
Arm fat percentage (right)	0.1	0.5	1.4	0.4	0.2	1.1	-0.1	0.1	1.1	0.8	0.5	-1.2	0.6
Body fat percentage	0.1	0.4	2.1	0.2	-0.2	0.3	-0.5	-0.9	0.5	0.1	-0.5	-1.5	-0.4
Medication: Allopurinol	0.1	0.2	0.4	-0.1	-0.1	-0.5	-0.3	-0.1	-0.2	0.6	-0.4	0.5	-0.6
Arm fat percentage (left)	0.1	0.5	2.8	0.3	-0.0	0.6	-0.7	-0.6	0.7	0.4	-0.3	-1.7	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.5	0.2	0.0	-0.8	-0.2	0.4	-0.8	-0.1	-0.5	0.1
Neck or shoulder pain in last month	0.0	0.1	0.2	0.4	-0.0	-0.3	-0.1	0.4	0.3	-0.2	0.1	0.0	0.4

Hub : Genes

ABCC8

Models

Trait associations