[Hub]/) : Traits : Impedance of leg (right) : ← →

chr11:45,945,837-48,485,877

Best TWAS P=1.95e-12 · Best GWAS P=7.55e-13 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	MADD	0.09	0.03	enet	22	0.04	1.9e-03	6.6	-5.8	7.6e-09	-0.64	0.05	0.62	TRUE
2	GTEx	Artery Tibial	MADD	0.09	0.00	enet	13	0.02	1.1e-02	3.3	-5.3	1.5e-07	-0.62	0.18	0.62	FALSE
3	GTEx	Brain Cerebellar Hemisphere	RP11-750H9.5	0.17	0.25	lasso	6	0.21	3.5e-06	5.6	-5.6	2.1e-08	-0.80	0.30	0.34	FALSE
4	GTEx	Cells Transformed fibroblasts	MADD	0.19	0.00	enet	17	0.09	3.3e-07	3.3	-5.6	1.9e-08	-0.27	0.50	0.10	FALSE
5	GTEx	Esophagus Mucosa	MADD	0.27	0.04	enet	18	0.12	4.1e-08	3.5	-6.3	2.6e-10	-0.54	0.18	0.35	TRUE
6	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	3.0	-5.6	1.7e-08	-0.65	0.44	0.41	TRUE
7	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	-4.1	6.5	6.8e-11	0.82	0.06	0.90	FALSE
8	GTEx	Nerve Tibial	NR1H3	0.10	0.00	enet	24	0.08	4.7e-06	4.4	7.0	1.9e-12	0.40	0.06	0.33	TRUE
9	GTEx	Nerve Tibial	CELF1	0.08	0.02	enet	15	0.06	4.3e-05	6.6	-6.1	1.2e-09	-0.79	0.02	0.90	FALSE
10	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	5.6	-5.7	1.5e-08	-0.74	0.30	0.55	FALSE
11	GTEx	Thyroid	MADD	0.11	0.00	enet	13	0.01	6.1e-02	-3.7	-6.0	2.1e-09	-0.43	0.06	0.16	TRUE
12	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	-4.1	-6.4	1.4e-10	-0.44	0.14	0.17	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	FNBP4	0.04	0.04	lasso	3	0.04	8.2e-06	3.9	-5.2	2.3e-07	-0.86	0.32	0.68	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	ATG13	0.05	0.02	bslmm	266	0.03	1.3e-04	-3.6	5.3	1.0e-07	0.35	0.07	0.84	TRUE
15	YFS	Blood	DDB2	0.02	0.00	bslmm	306	0.01	1.9e-04	1.6	-5.3	1.2e-07	-0.10	0.25	0.02	FALSE
16	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	7.0	-6.1	1.1e-09	-0.74	0.01	0.98	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	ACP2	0.02	0.01	blup	44	0.02	2.7e-04	3.3	-5.2	2.1e-07	-0.13	0.03	0.24	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	MADD	0.11	0.03	enet	14	0.06	1.4e-11	3.0	-6.1	1.1e-09	-0.49	0.36	0.58	TRUE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	C1QTNF4	0.03	0.02	blup	15	0.02	1.3e-03	-4.1	5.1	2.7e-07	0.62	0.10	0.21	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MADD	0.16	0.05	blup	64	0.08	2.2e-09	-4.0	-5.8	6.3e-09	-0.30	0.74	0.19	TRUE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	MADD	0.15	0.04	enet	10	0.06	4.5e-07	3.0	-5.8	6.9e-09	-0.40	0.18	0.10	TRUE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MADD	0.21	0.04	blup	64	0.07	1.3e-03	1.6	-5.2	2.1e-07	-0.15	0.06	0.10	TRUE
23	The Cancer Genome Atlas	Thyroid Carcinoma	C1QTNF4	0.04	0.01	blup	15	0.03	7.9e-04	-4.1	5.7	1.1e-08	0.55	0.01	0.75	FALSE