TWAS hub - DDB2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0270	0.0160	2.4e-02	0.020	0.001	0.001	0.005	0.000	1.5e-03	0.24000	2.7e-01	0.07900	2.8e-01
2	GTEx	Skin Not Sun Exposed Suprapubic	0.0690	0.0390	4.8e-03	0.023	NA	0.038	NA	0.023	1.8e-02	NA	3.5e-03	NA	1.8e-02
3	GTEx	Skin Sun Exposed Lower leg	0.0780	0.0300	9.6e-07	0.096	NA	0.093	NA	0.104	2.5e-08	NA	4.4e-08	NA	5.8e-09
4	METSIM	Adipose	0.0258	0.0137	5.2e-04	0.027	0.017	0.016	0.016	0.023	6.2e-05	0.00110	1.4e-03	0.00140	1.9e-04
5	NTR	Blood	0.0075	0.0049	1.1e-02	0.003	0.000	-0.001	0.000	0.007	3.5e-02	0.26000	6.1e-01	0.21000	2.2e-03
6	ROSMAP	Brain Pre-frontal Cortex	0.0401	0.0186	7.4e-05	0.032	0.027	0.031	0.027	0.026	4.6e-05	0.00018	7.1e-05	0.00016	2.3e-04
7	YFS	Blood	0.0202	0.0098	5.7e-04	0.000	0.010	0.006	0.010	0.002	4.8e-01	0.00021	3.8e-03	0.00019	6.8e-02
8	TCGA	Lung Squamous Cell Carcinoma	0.0168	0.0099	5.5e-03	0.030	0.017	0.018	NA	0.023	2.2e-04	0.00440	3.2e-03	NA	1.0e-03
9	TCGA	Thyroid Carcinoma	0.0590	0.0330	1.9e-04	0.037	0.012	0.026	NA	0.016	1.6e-04	0.02000	1.3e-03	NA	8.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
HDL Cholesterol	21.5	35.9	75.7	3.9	6.0	5.1	-4.5	-8.7	-3.1	-5.6	8.0	6.7
Heel T-Score	16.3	129.7	285.6	3.7	14.3	16.9	-13.3	-11.6	-12.4	3.5	9.4	9.9
Heel bone mineral density (BMD) T-score, automated (right)	14.2	32.4	65.6	1.9	7.2	8.1	-6.5	-6.2	-6.5	1.2	4.7	5.1
High blood pressure	12.8	35.6	65.4	-3.2	-6.1	-5.2	4.7	8.1	4.4	4.8	-7.4	-7.8
Hypertension (Self-reported)	12.4	34.4	66.6	-3.1	-5.5	-4.9	4.5	8.2	4.4	5.3	-7.1	-7.8
Heel bone mineral density (BMD) T-score, automated (left)	12.2	27.7	59.0	2.0	6.5	7.7	-5.8	-5.5	-6.0	1.8	4.0	5.0
Vascular/heart problems diagnosed by doctor	11.2	30.6	59.8	2.4	5.5	4.8	-4.4	-7.7	-4.5	-4.8	6.6	7.1
Fasting Glucose	10.5	12.5	27.6	3.8	4.6	3.2	-2.0	-3.5	-1.0	-0.5	5.2	4.8
Miserableness	9.3	16.1	33.1	-0.5	-5.0	-5.8	5.6	3.4	4.6	-0.9	-3.2	-3.5
Depressed Affect (Nagel 2018)	8.9	18.6	39.7	0.6	-4.7	-6.3	6.3	4.0	5.9	-1.0	-2.5	-2.8
Fed-up feelings	8.7	15.9	31.7	1.1	-4.5	-5.6	5.6	3.8	5.6	-0.3	-2.1	-2.8
Systolic Blood Pressure	8.6	42.8	76.9	1.9	-5.3	-5.5	6.2	8.8	8.6	6.2	-4.4	-8.7
Systolic blood pressure, automated reading	7.5	21.9	41.2	2.3	-3.3	-3.5	4.8	6.4	6.0	5.7	-2.5	-5.4
Medication: Blood pressure	7.0	12.3	26.7	-0.0	-2.8	-2.6	2.8	5.2	3.2	4.4	-3.7	-4.4
Mean time to correctly identify matches	7.0	13.4	32.8	0.0	4.7	5.7	-5.4	-1.5	-4.4	2.2	1.9	2.4
Cardiovascular Disease	6.9	22.7	52.6	-2.2	-3.9	-2.9	2.9	7.2	2.8	5.3	-6.1	-6.4
Eye problems/disorders: Glaucoma	6.8	8.0	21.1	2.0	2.5	1.2	-1.2	-3.6	-0.9	-3.7	3.3	4.6
Medication: Bendroflumethiazide	6.7	10.2	17.1	-1.8	-3.3	-3.0	2.7	4.1	2.1	2.5	-4.1	-4.0
Medication: Blood pressure	6.6	12.5	25.9	-3.5	-3.5	-2.6	2.0	4.5	1.4	2.6	-5.1	-4.8
Reaction Time	6.2	11.7	27.8	0.2	4.5	5.3	-5.0	-1.4	-4.2	2.1	1.9	2.2
Hearing difficulty/problems with background noise	6.2	9.9	22.8	0.4	-3.7	-4.8	4.2	2.4	4.5	-1.1	-0.9	-2.6
Medication: Lisinopril	6.0	7.7	15.7	-1.0	-3.1	-2.6	2.1	4.0	2.4	1.5	-3.8	-3.1
Neuroticism (Nagel 2018)	5.9	13.8	29.6	-0.6	-4.3	-5.4	4.6	3.2	4.4	-1.5	-2.9	-3.8
Neuroticism	5.9	14.3	32.4	1.0	-4.0	-5.7	5.6	3.4	5.3	-1.1	-1.4	-2.3
Mouth/teeth dental problems: Bleeding gums	5.5	7.1	24.3	-4.9	-0.9	0.4	-2.0	2.5	-1.7	1.1	-3.9	-3.1
Medication: Amlodipine	5.5	7.7	20.2	-0.0	-1.7	-2.2	2.5	4.5	2.7	3.5	-2.4	-3.2
Forced vital capacity (FVC), Best measure	5.1	18.5	33.1	2.5	5.3	4.7	-3.9	-5.8	-2.8	-1.9	5.7	4.3
Triglycerides	4.7	7.8	13.0	-2.8	-3.3	-3.5	2.6	3.1	1.5	-1.1	-3.6	-2.5
Glaucoma (self-reported)	4.6	5.4	12.6	0.9	2.0	1.1	-1.3	-3.6	-1.1	-3.4	2.6	2.9
Forced expiratory volume in 1-second (FEV1), predicted	4.5	9.3	16.0	1.8	3.7	3.5	-3.2	-4.0	-2.0	-1.3	4.0	2.7
Mood swings	4.5	8.2	15.4	-1.1	-3.4	-3.9	3.6	2.7	3.1	-0.7	-2.7	-2.8
Neuroticism score	4.3	9.1	21.0	0.7	-3.1	-4.5	4.6	2.4	4.1	-1.2	-1.2	-2.0
Commuting to job workplace: Car/motor vehicle	4.2	4.8	7.6	-1.1	2.4	2.5	-2.8	-2.7	-2.4	-1.3	1.5	2.2
Forced vital capacity (FVC)	4.1	15.7	28.4	3.0	4.7	4.0	-3.0	-5.2	-2.3	-1.9	5.3	4.6
Depression (Nagel 2018)	3.9	5.8	15.3	1.2	-2.0	-3.6	3.9	1.2	3.6	-1.9	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	3.7	12.0	28.3	1.2	3.8	3.4	-3.0	-5.3	-2.7	-2.6	4.2	3.2
Guilty feelings	3.7	5.5	10.8	1.4	-1.4	-2.0	2.9	2.9	3.3	2.4	-1.0	-2.7
Diastolic blood pressure, automated reading	3.7	11.6	24.9	0.3	-2.8	-2.2	2.7	5.0	3.6	4.2	-2.8	-4.6
Frequency of depressed mood in last 2 weeks	3.6	5.0	14.0	0.3	-2.1	-3.7	3.0	1.0	3.1	-2.5	-0.2	-0.8
Medication for cholesterol, blood pressure or diabetes	3.6	5.9	16.6	-0.5	1.8	1.6	-1.7	-4.1	-2.4	-3.2	2.3	2.5
Hair/balding pattern: Pattern 3	3.5	5.2	11.0	-2.2	-2.0	-1.9	2.0	2.8	0.6	0.9	-3.3	-3.2
Neuroticism (2016)	3.4	4.9	12.0	0.3	-2.2	-3.1	3.2	1.8	3.5	-1.4	-0.6	-1.3
Migraine (self-reported)	3.4	4.2	9.4	2.2	0.9	0.5	-0.4	-3.0	0.3	-2.3	2.8	3.1
Comparative height size at age 10	3.4	18.6	38.4	5.0	6.2	4.5	-2.6	-4.0	-1.4	0.9	6.2	4.3
Number of self-reported non-cancer illnesses	3.4	5.8	14.4	1.9	-2.1	-3.0	3.0	2.8	3.8	1.0	-0.7	-1.5
High blood pressure (siblings)	3.3	4.8	16.0	-1.3	-1.2	-0.7	0.3	2.6	0.8	3.0	-2.6	-4.0
Suffer from ‘nerves’	3.3	5.2	14.4	0.8	-1.7	-3.3	2.7	0.3	3.1	-3.8	0.9	-0.1
High blood pressure (mother)	3.2	4.5	6.7	-0.8	-2.2	-2.4	2.6	2.5	1.7	1.6	-2.4	-2.3
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.2	13.9	1.1	-1.6	-3.7	3.6	1.8	3.1	-1.3	-0.2	-1.3
Breastfed as a baby	3.2	4.0	9.2	2.2	2.3	1.7	-0.8	-2.3	-0.5	-0.3	3.0	2.6
Blood clot in the leg (DVT)	3.2	4.1	7.8	2.3	2.3	2.0	-2.2	-2.8	-0.4	-0.7	1.9	2.3
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.9	10.2	-1.2	1.8	2.2	-2.0	-2.6	-3.2	-1.4	0.3	1.4
Deep venous thrombosis (DVT) (self-reported)	3.2	4.1	7.2	2.1	2.5	2.2	-2.4	-2.7	-0.6	-0.2	1.9	2.0
Nervous feelings	3.1	5.7	9.6	-2.8	-2.4	-2.9	1.5	1.8	1.2	-2.3	-2.7	-3.1
Time employed in main current job	3.1	3.6	6.1	-1.2	2.5	2.2	-2.2	-2.0	-2.2	-1.5	1.5	1.1
Comparative body size at age 10	3.1	8.5	47.1	1.1	1.0	1.0	-0.2	3.5	0.4	6.9	-1.6	-3.3
Illnesses of father: None of the above (group 1)	3.1	3.8	6.6	-0.9	2.0	1.8	-2.2	-2.6	-1.9	-2.2	1.7	1.9
Illnesses of siblings	3.0	4.2	13.6	0.5	0.4	0.3	0.3	-3.0	-1.1	-3.2	1.8	3.7
Loneliness, isolation	3.0	4.1	10.2	1.3	-1.2	-3.0	3.0	1.1	3.2	-1.9	0.5	-0.0
Verbal and Numeric Reasoning (VNR)	2.9	6.9	21.3	2.2	0.1	-2.0	2.0	-2.3	2.1	-4.6	3.0	3.0
Sensitivity / hurt feelings	2.9	5.0	9.1	-1.7	-2.8	-3.0	2.3	2.1	1.4	-0.7	-2.4	-2.7
Hayfever/allergic rhinitis (self-reported)	2.9	3.8	9.6	-0.1	-2.6	-3.1	2.5	1.6	2.5	-1.1	-0.9	-0.7
Prospective memory result	2.9	3.6	19.0	-0.2	0.7	1.0	-0.4	2.8	-0.3	4.4	-1.2	-1.6
Medication for cholesterol	2.9	4.4	9.4	0.9	1.9	1.0	-1.5	-3.1	-0.9	-2.7	2.9	2.6
Chronotype (morning person)	2.8	6.4	22.6	-1.1	0.2	1.2	-1.4	3.2	-0.8	4.8	-2.8	-3.3
Trunk fat-free mass	2.8	15.9	31.5	4.2	5.6	5.1	-3.0	-3.4	-2.3	1.6	4.7	4.1
Forced expiratory volume in 1-second (FEV1)	2.8	9.6	22.4	1.3	3.1	3.1	-2.5	-4.7	-2.5	-2.5	3.5	3.4
Hair/balding pattern: Pattern 4	2.8	6.8	11.8	1.3	-3.2	-2.9	3.2	3.3	3.4	1.9	-1.8	-0.0
Lung cancer (father)	2.7	3.2	6.6	0.4	2.0	1.8	-1.5	-2.2	-1.4	-1.5	1.9	2.6
Trunk predicted mass	2.7	15.6	31.0	4.2	5.6	5.1	-2.9	-3.3	-2.2	1.7	4.7	4.0
Standing height	2.7	26.7	57.0	6.0	7.0	4.8	-2.7	-5.5	-1.3	-1.4	7.5	5.9
Arm fat percentage (left)	2.7	10.8	28.0	-1.4	-1.6	-1.0	0.9	5.0	0.3	5.3	-4.7	-4.0
Osteoporosis (self-reported)	2.6	3.3	9.3	0.4	-2.1	-3.1	2.9	0.6	2.0	-1.6	-0.1	-0.4
Number of incorrect matches in round	2.5	4.1	8.6	-1.6	1.9	2.5	-2.9	-2.6	-2.9	-0.7	0.7	0.3
Fluid intelligence score	2.5	5.2	21.5	1.3	0.6	-1.1	1.1	-2.7	1.2	-4.6	2.5	2.5
Myopia	2.5	3.6	10.9	1.7	2.7	1.5	-0.8	-1.8	0.3	-0.9	3.3	2.2
Number of treatments/medications taken	2.4	4.3	7.4	0.3	-2.1	-2.5	2.3	2.7	2.4	1.2	-2.1	-2.1
Age when periods started (menarche)	2.4	5.7	29.9	-1.6	-1.1	-0.5	0.0	-2.9	-1.7	-5.5	0.5	2.4
Commuting to job workplace: Walk	2.4	2.6	6.2	0.9	-1.5	-2.1	2.5	1.5	2.3	0.1	-1.0	-1.2
Height	2.3	44.4	98.6	8.9	8.7	5.5	-2.8	-6.3	-0.6	-1.5	9.9	8.1
Ever used hormone-replacement therapy (HRT)	2.3	3.0	5.2	0.9	-2.3	-2.1	2.3	2.0	1.8	1.3	-1.4	-0.6
Medication for hormone replacement therapy	2.3	2.5	6.8	2.5	1.2	1.7	-0.4	-0.8	-0.0	0.9	2.0	2.6
Arm fat percentage (right)	2.3	9.2	24.3	-1.5	-1.3	-0.6	0.5	4.6	-0.1	4.9	-4.4	-3.7
Overall health rating	2.3	5.0	13.2	3.0	-0.6	-2.3	2.7	2.3	3.6	1.7	0.6	-1.2
Leg fat percentage (left)	2.3	8.2	17.6	-2.0	-1.9	-1.5	1.2	4.2	0.8	3.3	-4.2	-3.8
Intelligence (Savage-Jansen 2018)	2.2	6.7	26.9	1.6	0.6	-1.5	1.3	-2.8	1.7	-5.2	3.3	2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	3.0	7.8	1.4	-1.3	-2.5	2.8	0.8	2.7	-0.9	0.5	-0.2
Birth weight of first child	2.2	4.1	11.2	0.1	1.0	1.0	-1.4	-3.3	-1.6	-3.0	1.7	2.7
Leg fat percentage (right)	2.2	7.9	18.3	-2.3	-2.2	-1.8	1.4	3.9	0.8	2.7	-4.3	-3.7
Cholesterol lowering medication	2.2	3.2	8.5	-1.3	-2.4	-1.8	1.4	1.9	0.3	0.0	-2.9	-2.1
BMI	2.1	12.2	44.2	-1.5	-0.6	0.2	0.2	5.3	0.1	6.7	-4.6	-3.7
Sitting height	2.1	14.8	35.0	4.5	5.9	4.9	-3.1	-2.6	-0.7	2.0	5.1	2.6
Ever unenthusiastic/disinterested for a whole week	2.1	2.6	8.6	1.0	2.9	1.9	-1.2	-1.3	-1.3	0.5	2.0	0.7
Medication: Ramipril	2.1	2.6	8.2	-0.9	-0.1	-0.0	-0.3	2.3	0.9	2.5	-1.4	-2.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	9.5	1.9	0.0	-1.6	1.3	2.8	3.1	0.9	0.4	-1.8
Body fat percentage	2.1	8.4	20.9	-1.3	-1.5	-1.4	1.2	4.6	0.8	4.0	-4.1	-3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.1	2.5	4.9	-1.5	0.9	1.8	-2.2	0.8	-1.6	1.9	-1.3	-1.6
Basal cell carcinoma (self-reported)	2.1	2.5	5.8	-0.3	-1.2	-1.0	0.8	2.4	1.2	2.4	-1.1	-2.3
Worry (Nagel 2018)	2.0	4.2	9.3	-1.1	-1.9	-3.0	2.2	1.2	2.2	-2.3	-1.2	-2.3
LDL Cholesterol	2.0	3.1	9.9	-1.7	-2.1	-2.4	1.8	-0.4	0.1	-3.1	-1.2	0.4
Primary Biliary Cirrhosis	2.0	2.8	6.2	2.1	2.5	1.9	-1.7	-0.8	-0.6	1.2	2.0	1.1
Smoking Status	2.0	4.7	10.3	2.9	2.7	2.4	-1.9	-1.0	-0.1	0.9	2.4	3.2
Severe depression (siblings)	2.0	2.3	5.2	-0.5	1.9	2.2	-2.3	-1.6	-1.7	-0.4	1.0	0.3
Happiness	2.0	2.4	5.2	1.2	-1.4	-1.9	2.3	1.8	2.3	0.3	-0.1	-0.7
Exposure to tobacco smoke outside home	2.0	2.7	8.4	-1.6	-0.6	-1.8	0.9	2.0	1.3	0.0	-1.6	-2.9
Shortness of breath walking on level ground	2.0	2.4	7.9	0.9	-0.6	-2.1	2.2	1.8	2.8	0.1	-0.0	-0.4
Whole body fat-free mass	2.0	11.6	24.4	4.0	4.9	4.5	-2.4	-2.1	-1.9	2.8	3.6	3.1
Whole body water mass	2.0	11.6	24.0	4.0	4.9	4.5	-2.4	-2.2	-1.9	2.6	3.6	3.1
Ever taken oral contraceptive pill	2.0	2.3	6.0	0.9	0.0	-0.7	1.3	-2.0	0.1	-2.4	1.5	2.3
Blood Platelet Count	1.9	22.6	81.5	9.0	4.2	2.7	-0.5	-1.3	2.8	3.7	8.0	3.2
Pulse rate, automated reading	1.9	6.3	14.4	3.5	2.7	1.5	-0.5	-2.3	0.1	-0.9	3.8	3.7
Average weekly beer plus cider intake	1.9	2.7	8.2	1.3	2.9	2.2	-1.7	-0.6	-0.2	1.2	2.2	0.7
Risk taking	1.9	2.8	5.4	1.4	2.3	2.1	-1.5	-1.0	-0.9	1.1	2.3	1.8
Lupus	1.8	2.7	6.0	2.2	0.7	0.1	0.2	-2.5	0.8	-1.8	2.4	1.6
Schizophrenia (2014)	1.8	4.1	10.6	1.3	3.3	2.7	-2.2	0.9	-0.5	2.9	1.5	-0.5
Trunk fat percentage	1.8	7.1	18.3	-0.9	-1.2	-1.2	1.1	4.3	0.7	3.9	-3.8	-3.3
Supplements: Glucosamine	1.8	2.4	5.9	0.6	1.5	2.4	-1.5	-1.7	-1.3	1.0	1.4	1.8
Falls in the last year	1.8	2.5	5.5	2.4	1.2	-0.1	0.9	1.4	2.2	2.3	1.5	-0.6
Medication: Allopurinol	1.8	2.4	6.6	0.3	-0.8	-0.9	1.0	2.1	1.6	2.2	-0.7	-2.6
Schizophrenia vs Biploar Disorder	1.7	2.3	6.1	0.2	1.8	2.2	-1.7	0.9	-1.6	2.5	0.5	0.2
Number of children fathered	1.7	1.9	4.2	-0.6	1.4	2.1	-1.7	-1.0	-2.0	1.0	-0.5	1.2
Arm predicted mass (right)	1.7	8.5	16.8	4.0	4.1	3.4	-1.6	-2.0	-0.9	2.0	3.4	3.1
Knee pain experienced in last month	1.7	2.7	5.9	0.1	2.3	1.0	-0.8	-2.4	-0.4	-2.2	2.3	0.9
Long-standing illness, disability or infirmity	1.7	2.5	7.1	2.7	2.0	0.8	-0.2	0.3	1.2	2.4	1.9	0.7
Illnesses of father: High blood pressure	1.7	2.1	5.2	-1.4	-0.7	-0.3	0.3	1.9	0.6	1.9	-1.8	-2.3
Prostate Cancer	1.6	2.3	6.7	-1.8	-2.1	-1.8	1.1	-0.7	-0.2	-2.6	-1.2	0.2
Lung FVC	1.6	8.0	14.0	0.4	3.0	3.7	-3.6	-3.6	-2.7	-0.6	2.7	2.8
Body mass index (BMI)	1.6	6.9	24.7	-0.8	-0.8	-0.1	0.4	3.8	-0.1	5.0	-3.5	-3.0
Pulse rate	1.6	2.7	8.1	2.4	2.2	1.0	-0.8	-1.3	0.2	-0.1	2.9	1.5
Exposure to tobacco smoke at home	1.6	1.8	5.6	-2.0	-0.7	-0.6	0.2	1.3	-0.3	0.9	-1.7	-2.4
Arm fat-free mass (right)	1.6	8.2	15.8	4.0	4.0	3.3	-1.6	-1.9	-0.8	1.9	3.4	3.0
Leg fat-free mass (right)	1.6	8.4	20.1	3.6	4.0	3.7	-1.6	-0.3	-1.5	4.5	2.2	1.6
Friendships satisfaction	1.6	2.0	6.8	2.6	0.6	-0.3	0.7	-0.1	1.5	-0.2	2.0	2.0
Leg predicted mass (right)	1.6	8.4	19.5	3.5	4.1	3.7	-1.8	-0.3	-1.6	4.4	2.2	1.6
Basal metabolic rate	1.6	8.7	19.4	3.5	4.4	3.9	-2.0	-1.3	-1.6	3.1	2.8	2.2
Ever had prostate specific antigen (PSA) test	1.6	1.8	4.6	1.0	-1.0	-1.8	2.0	1.4	2.1	0.5	0.0	-0.4
Angina	1.5	2.0	5.1	-0.7	-1.4	-2.3	1.6	1.2	1.6	-0.3	-1.7	-1.0
Leg fat-free mass (left)	1.5	7.8	18.5	3.4	3.9	3.6	-1.6	-0.3	-1.5	4.3	2.1	1.6
Maternal smoking around birth	1.5	2.2	9.1	0.7	0.1	-0.4	0.2	2.5	1.2	3.0	-0.6	-1.4
Hip circumference	1.5	6.4	15.3	-0.0	-1.2	-1.3	1.7	3.8	1.4	3.9	-3.0	-3.3
Father’s age at death	1.5	2.0	3.6	-1.9	-1.8	-1.6	1.8	0.8	0.4	-1.4	-1.3	-1.2
Had major operations	1.5	1.8	5.4	0.6	-1.0	-2.0	1.8	1.2	2.3	-0.8	0.2	0.2
Back pain experienced in last month	1.5	2.2	5.0	0.2	-1.8	-2.2	2.1	-0.2	1.7	-1.9	-0.2	-0.6
Arm fat-free mass (left)	1.5	7.6	16.2	3.5	4.0	3.3	-1.7	-1.9	-1.2	1.8	3.2	2.7
Unable to work because of sickness or disability	1.5	1.9	6.2	2.5	1.4	0.5	0.4	0.6	1.3	2.2	1.4	0.4
Pain experienced in last month	1.5	2.5	8.1	0.7	1.4	2.4	-1.9	0.3	-1.5	2.8	-0.0	0.2
Schizophrenia (2018)	1.4	2.9	12.4	0.6	1.8	2.0	-1.2	1.9	-0.5	3.5	-0.0	-0.8
Major Depression (MDD)	1.4	1.6	4.5	0.3	0.2	-0.9	1.0	1.9	2.1	0.9	-0.2	-2.0
Body Mass Index (BMI) (2010)	1.4	1.9	5.4	-0.7	-0.7	-0.4	0.2	2.3	-0.3	1.9	-2.3	-1.0
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	6.9	2.6	1.3	0.7	0.3	0.4	0.6	1.8	1.5	0.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	5.4	-0.9	-0.5	0.6	-0.5	1.1	-1.7	1.7	-2.3	0.1
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	3.3	0.4	-1.2	-1.4	1.8	1.5	1.8	0.4	-1.0	-1.1
Leg predicted mass (left)	1.4	7.6	18.7	3.3	3.8	3.5	-1.6	-0.2	-1.5	4.3	2.0	1.5
Mouth/teeth dental problems	1.4	2.1	7.9	2.8	-0.1	-0.6	1.9	-0.9	1.1	-0.1	1.9	1.2
Medication: Simvastatin	1.4	2.0	4.8	0.3	-2.0	-1.3	1.2	2.2	0.9	1.0	-1.8	-1.0
Asthma	1.4	2.7	6.0	0.3	-1.9	-2.0	1.4	1.7	2.4	0.4	-1.3	-1.9
Arm fat mass (right)	1.4	5.6	24.1	-0.1	0.1	0.6	-0.0	3.5	-0.4	4.9	-2.8	-2.4
Length of working week for main job	1.4	1.5	3.9	1.2	1.5	1.3	-1.2	-1.4	0.0	0.3	2.0	0.8
Ever highly irritable/argumentative for 2 days	1.4	1.7	5.6	2.4	1.6	0.2	0.9	-0.6	0.9	0.8	2.1	0.1
Headache pain in last month	1.4	2.4	12.8	-1.3	-0.8	-1.4	0.9	-1.8	-0.2	-3.6	0.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	3.5	0.3	-1.1	-1.5	1.1	1.6	1.9	0.8	-0.8	-1.8
Supplements: Vitamin C	1.4	1.6	4.0	-0.9	1.3	1.5	-2.0	-1.7	-1.2	-0.9	1.0	0.3
Pack years of smoking	1.4	2.0	4.4	1.9	2.0	1.0	-0.1	1.1	1.3	2.1	1.5	0.0
Arm predicted mass (left)	1.4	6.9	14.8	3.3	3.9	3.2	-1.7	-1.9	-1.2	1.5	3.0	2.7
Mean Putamen Volume	1.3	1.5	4.2	-0.9	1.3	1.4	-1.3	1.2	-0.9	2.1	-0.7	-0.3
Past tobacco smoking	1.3	2.4	7.2	-2.7	-1.3	-1.2	0.7	-0.7	-1.1	-2.5	-1.4	-0.6
Alcohol usually taken with meals	1.3	2.1	8.6	-1.4	-1.5	-1.3	0.6	-1.7	-0.4	-2.9	-0.8	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	6.4	-0.9	0.4	0.1	-0.7	-1.7	-0.7	-2.5	1.0	1.1
Qualifications: nursing, teaching	1.3	2.0	4.2	0.9	-1.5	-1.0	1.7	2.1	1.4	2.0	-0.7	-0.5
Supplements: Calcium	1.3	1.4	3.3	1.8	0.2	-1.2	1.0	-0.3	1.6	-0.7	1.8	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	5.0	0.4	-0.7	-2.2	1.9	0.8	2.2	-1.2	0.5	-0.7
Hair/balding pattern: Pattern 2	1.2	1.5	3.1	0.9	1.2	1.8	-1.6	-1.5	-0.8	-0.0	1.6	0.4
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	7.6	-0.2	-1.3	-1.1	0.4	-1.4	0.7	-2.8	-0.1	-0.4
Peak expiratory flow (PEF)	1.2	2.7	6.1	1.5	1.0	1.4	-0.7	-2.5	-1.1	-1.3	1.8	2.5
Hypothyroidism/myxoedema (self-reported)	1.2	2.4	8.8	0.8	-1.0	-0.7	0.5	2.5	0.9	3.0	-1.4	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.3	-0.8	-0.2	0.2	-0.7	-1.6	-1.6	-1.8	-0.0	1.3
Asthma (self-reported)	1.2	2.3	5.6	0.4	-1.6	-1.9	1.4	1.6	2.4	0.5	-1.0	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	5.5	-2.0	0.9	1.6	-2.3	-2.0	-2.3	-0.7	-0.0	-0.4
Arm fat mass (left)	1.2	5.1	23.8	0.2	0.3	0.6	0.1	3.3	-0.3	4.9	-2.6	-2.0
High cholesterol (Self-reported)	1.2	2.1	7.3	0.1	-1.5	-1.4	1.0	2.7	1.1	1.1	-1.5	-1.3
Bipolar Disorder or Schizophrenia	1.1	2.8	7.8	0.9	2.8	2.3	-1.7	0.8	-0.3	2.4	1.3	-0.5
Bipolar Disorder (2011)	1.1	1.1	3.0	-0.2	1.7	1.5	-1.3	-0.7	-0.4	-0.2	0.9	-1.0
Waist Hip Ratio (WHR)	1.1	5.0	12.0	2.2	1.9	-0.1	-0.3	-2.8	-0.0	-3.5	3.3	2.5
Pack years adult smoking proportion	1.1	1.6	3.7	1.5	1.9	0.9	-0.1	0.9	1.2	1.8	1.4	-0.2
Current tobacco smoking	1.1	1.8	6.2	2.5	1.1	0.1	0.1	-0.2	1.6	-0.3	1.8	1.8
Relative age voice broke	1.1	1.6	3.3	0.3	1.7	1.8	-1.7	-1.5	-1.3	-0.1	1.2	0.2
Medication: Levothyroxine sodium	1.1	1.9	7.4	0.6	-0.9	-0.5	0.4	2.1	0.8	2.7	-1.2	-1.4
Depression (self-reported)	1.1	1.4	4.8	2.2	1.0	-0.1	0.8	0.3	1.6	0.5	1.7	-0.3
Loud music exposure frequency	1.1	1.2	2.8	-1.7	-0.4	0.5	-1.1	0.5	-1.1	1.1	-1.7	-1.0
Whole body fat mass	1.1	4.7	19.0	-0.0	0.1	0.1	0.4	3.4	0.2	4.4	-2.5	-2.3
Leg fat mass (right)	1.1	4.1	16.3	-0.1	-0.2	0.0	0.5	3.1	0.3	4.0	-2.4	-2.2
Medication: Aspirin	1.1	1.5	4.2	0.1	-0.5	-0.6	0.7	2.0	1.4	1.9	-0.8	-1.3
Illnesses of father: Heart disease	1.1	1.5	3.1	0.9	-0.8	-1.4	1.4	1.7	1.7	1.2	-0.4	-0.5
Leg fat mass (left)	1.1	4.3	19.6	0.1	0.3	0.4	0.2	3.1	0.2	4.4	-2.2	-2.1
Bipolar Disorder (2018)	1.0	1.6	4.7	0.7	2.2	1.2	-1.3	-1.1	0.1	-0.5	2.1	0.2
Ovarian Cancer	1.0	1.3	3.9	0.6	0.5	0.7	-0.7	-2.0	-0.7	-1.6	1.2	1.3
Blood White Count	1.0	7.2	15.2	-3.1	-3.0	-0.8	0.8	2.3	-0.1	3.6	-3.9	-3.3
Hypothyroidism (self reported)	1.0	2.4	14.2	1.8	-0.0	0.2	0.3	1.9	0.6	3.8	-0.4	-0.3
Hand grip strength (left)	1.0	2.6	5.5	1.9	1.5	2.4	-1.8	-1.1	-0.9	0.7	2.0	1.6
Supplements: Zinc	1.0	1.1	2.2	1.1	1.3	1.5	-1.1	-0.4	-0.2	0.9	1.4	0.9
Impedance of leg (right)	1.0	5.1	28.1	-2.0	-1.7	-2.4	0.9	-1.4	1.3	-5.3	0.1	0.1
Trunk fat mass	1.0	4.4	17.9	0.2	0.3	0.2	0.3	3.3	0.1	4.2	-2.4	-2.2
Number of live births	1.0	1.4	4.7	0.3	0.8	1.8	-1.9	0.2	-0.9	2.2	0.0	0.2
Qualifications: A levels/AS levels or equivalent	1.0	2.1	9.1	-0.4	-1.3	-1.9	1.5	-1.3	0.8	-3.0	0.4	0.5
Tense / ‘highly strung’	1.0	1.6	2.2	-1.5	-1.1	-1.4	1.3	1.4	1.0	0.1	-1.4	-1.5
Pulse wave reflection index	1.0	1.2	2.8	-0.4	-1.7	-0.9	1.4	1.1	0.5	1.0	-1.3	-0.9
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	4.8	0.2	-1.1	-1.9	1.9	-0.3	0.9	-2.2	0.1	0.4
Birth weight	1.0	2.2	4.8	1.9	1.4	1.2	-0.1	-2.2	-0.6	-0.7	2.1	1.7
Number of full brothers	1.0	1.2	6.0	0.8	0.1	0.7	-0.6	1.1	0.6	2.5	-0.1	-1.4
Pulse wave peak to peak time	1.0	1.2	2.5	-1.0	0.9	1.1	-1.4	-1.2	-1.6	-1.3	-0.0	0.7
Angina (self-reported)	1.0	1.4	4.0	-0.8	-1.1	-2.0	1.3	0.9	1.3	-0.4	-1.4	-0.6
Medication: Ibuprofen	1.0	1.2	5.3	-0.5	-1.4	-1.1	0.8	-1.0	0.3	-2.3	-0.7	-0.3
Chest pain or discomfort	1.0	1.5	3.2	1.2	0.9	-0.8	1.1	-0.9	1.8	-1.3	1.8	0.6
Smoking status: Current	1.0	1.6	5.1	2.2	1.0	-0.0	0.0	-0.3	1.7	-0.4	1.7	1.6
Average weekly champagne plus white wine intake	1.0	1.4	5.3	-1.9	0.6	0.3	-1.0	-1.4	-0.7	-2.3	-0.1	0.1
Hearing aid user	1.0	1.1	2.6	-1.3	0.1	-0.1	-0.2	1.6	0.4	1.5	-1.2	-1.3
Mother’s age at death	1.0	1.2	4.0	-1.9	-0.8	-1.1	0.8	-0.5	-0.1	-2.0	-0.3	-0.6
Fractured/broken bones in last 5 years	1.0	1.3	2.5	-0.2	-1.6	-1.6	1.5	1.1	1.5	-0.9	-0.5	-0.4
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.6	-0.6	1.4	1.2	-1.6	-0.7	-1.4	-0.2	0.2	0.3
Hair Pigment	0.9	25.0	47.9	2.9	5.2	4.4	-4.2	-6.9	-2.5	-3.9	6.7	6.2
Stomach or abdominal pain in last month	0.9	1.1	3.2	-0.6	1.8	0.8	-1.0	-1.4	-1.1	-1.0	0.8	0.2
Impedance of leg (left)	0.9	4.4	23.6	-1.7	-1.5	-2.4	0.9	-1.1	1.6	-4.9	0.1	-0.1
Had menopause	0.9	1.2	4.8	1.8	0.7	0.1	0.2	-0.4	0.7	0.2	1.1	2.2
Noisy workplace	0.9	1.1	5.0	0.4	1.5	1.3	-0.8	-0.0	-0.4	2.2	0.4	-0.4
Pulse wave Arterial Stiffness index	0.9	1.0	2.3	1.4	-0.6	-0.9	1.3	1.0	1.5	1.1	0.3	-0.3
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.3	1.2	1.1	1.2	-0.9	0.3	0.1	1.2	0.9	1.5
Age at first live birth	0.9	1.6	3.0	1.2	-1.2	-1.7	1.7	-0.8	1.2	-1.5	0.9	0.3
Neck or shoulder pain in last month	0.9	1.3	3.0	1.5	-0.1	-1.3	1.0	-0.8	1.7	-1.0	1.5	0.3
Ever had bowel cancer screening	0.9	1.0	2.5	-0.6	0.3	0.6	-1.0	-1.1	-1.3	-1.4	-0.0	1.6
Eye problems/disorders: Cataract	0.9	1.0	4.4	1.6	0.5	0.5	0.4	1.1	0.6	2.1	0.4	0.4
Financial situation satisfaction	0.9	1.1	3.7	1.0	0.9	0.0	-0.4	-0.4	0.5	-1.0	1.9	1.6
Ever smoked	0.9	1.6	5.7	2.4	0.8	0.7	-0.4	0.5	1.4	1.6	1.3	0.7
Alzheimer’s Disease (in mother)	0.8	0.9	4.4	-2.1	0.2	0.5	-0.8	-0.0	-1.0	-0.5	-1.1	-0.7
Rheumatoid Arthritis	0.8	1.1	3.6	-1.9	-1.0	-1.5	1.0	0.0	0.6	-1.3	-0.4	-0.3
Respiratory disease	0.8	1.7	4.2	1.0	-1.3	-1.6	1.5	1.4	2.0	0.5	-0.6	-1.1
Ever had hysterectomy (womb removed)	0.8	1.0	2.1	-0.8	-1.3	-1.2	0.9	0.0	0.6	-1.4	-0.8	-0.9
Chronic bronchitis/emphysema (father)	0.8	1.0	4.2	2.0	0.7	0.8	-0.5	0.6	0.5	1.6	0.4	0.4
Qualifications: None of the above	0.8	1.6	4.2	-0.4	-1.0	-1.2	0.6	2.0	1.1	1.3	-1.6	-1.4
Illnesses of mother	0.8	1.0	2.0	0.6	1.1	1.1	-1.0	-1.2	-0.9	-0.5	1.4	0.9
Leg pain on walking	0.8	1.0	3.1	1.8	0.2	-0.8	0.9	0.6	1.6	0.5	0.9	-0.0
Illnesses of siblings: Diabetes	0.8	1.0	3.0	-0.9	-0.3	0.0	-0.7	1.4	-0.0	1.1	-1.2	-1.7
Smoking status: Previous	0.8	1.2	3.6	1.0	1.4	1.5	-1.2	0.3	-0.2	1.9	0.7	0.1
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.6	-0.8	0.5	1.2	-1.5	0.6	-0.3	1.9	-0.5	-1.7
Commuting to job workplace: Public transport	0.8	0.9	1.5	0.8	-1.2	-0.9	1.0	1.2	0.9	0.9	-0.7	-1.0
Age started oral contraceptive pill	0.8	1.0	2.4	-1.1	-1.4	-1.6	1.3	0.4	0.2	-1.1	-0.5	0.2
Heart attack/myocardial infarction (self-reported)	0.8	1.0	4.8	2.2	0.6	-0.2	0.6	0.4	1.1	0.7	0.7	1.0
Alcohol drinker status: Previous	0.8	0.9	1.9	1.2	-0.2	-1.1	1.2	1.3	1.4	0.0	-0.4	-0.5
Alzheimer’s Disease (in father)	0.7	0.7	1.7	0.9	0.6	0.4	-0.6	-1.3	0.1	-1.3	1.2	0.5
Alzheimer’s Disease (including proxy)	0.7	1.0	3.2	-1.8	0.3	0.4	-1.1	-0.8	-0.6	-1.8	-0.1	-0.3
Breast Cancer	0.7	1.8	3.6	-1.8	-1.5	-1.5	1.1	0.5	0.7	-0.7	-1.9	-1.5
Crohns Disease (2012)	0.7	1.1	5.9	-0.1	0.7	0.2	1.0	1.4	0.4	2.4	-0.0	-0.5
Diabetes (father)	0.7	0.9	2.8	-1.4	-0.5	-0.3	0.0	1.2	-0.2	0.8	-0.9	-1.7
Medication: Atenolol	0.7	0.8	1.5	-1.0	0.1	1.2	-0.9	0.4	-1.2	1.2	-1.1	-0.2
Pain all over the body in last month	0.7	0.8	3.0	1.2	0.3	-0.1	0.8	0.6	1.0	1.7	0.3	0.4
Weight	0.7	3.4	15.2	2.0	2.3	2.0	-0.7	1.2	-0.5	3.9	0.2	-0.2
Alcohol intake versus 10 years previously	0.7	1.1	3.4	-1.7	0.0	0.8	-1.0	-0.2	-1.9	-0.3	-1.1	0.6
Medication: Cholesterol lowering	0.7	1.1	4.6	0.7	-0.5	-0.2	0.0	2.1	0.8	1.6	-0.9	-0.6
Gout (self-reported)	0.7	0.9	1.9	0.3	-0.4	-0.7	0.8	1.4	1.0	1.4	-0.4	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	4.1	0.8	0.6	0.4	0.0	1.2	0.5	2.0	0.2	-0.0
Medication for pain relief, constipation, heartburn	0.7	1.2	2.4	1.3	1.4	1.0	-0.6	-0.1	-0.3	0.9	1.6	1.4
Medication: Seretide 50 evohaler	0.7	0.8	2.4	1.0	1.3	0.5	-0.7	0.8	0.6	1.6	0.6	0.1
Age at last live birth	0.7	1.1	2.7	1.3	-0.2	-0.2	0.2	-1.6	0.2	-1.2	1.4	1.4
Osteoarthritis (self-reported)	0.7	1.0	3.1	1.8	-0.2	-1.0	1.6	0.2	0.9	0.2	0.3	1.0
Medication: Aspirin	0.7	1.0	3.5	0.1	-0.3	-0.2	0.4	1.8	0.5	1.9	-1.0	-0.7
Heart disease (siblings)	0.7	0.8	2.4	0.5	1.6	1.3	-1.3	-0.2	-0.6	0.4	0.8	0.4
Coronary Artery Disease (CAD)	0.6	0.7	2.8	0.1	-0.1	0.1	0.4	1.1	0.4	1.7	-1.0	-0.8
Hearing difficulty/problems: Yes	0.6	1.0	3.0	0.5	0.1	-0.9	0.7	-1.1	1.7	-1.0	1.4	-0.5
Relative age of first facial hair	0.6	1.2	2.8	0.9	1.7	1.3	-0.5	-1.5	-0.5	-0.2	1.5	0.9
Diabetes (mother)	0.6	0.7	3.0	0.3	-0.3	-0.6	0.6	-0.7	0.3	-1.7	0.0	1.4
Average weekly fortified wine intake	0.6	0.7	1.7	0.7	0.1	-1.1	0.7	0.3	1.2	-0.4	1.3	-0.7
Taking other prescription medications	0.6	0.9	2.8	1.7	1.4	0.4	-0.6	0.3	0.4	1.6	0.8	-0.2
Multivitamins +/- minerals	0.6	0.8	2.5	1.3	-0.5	-0.6	1.0	0.1	0.7	-0.2	0.8	1.6
Had other major operations	0.6	0.8	3.3	0.3	-0.3	-0.5	0.5	-1.2	-0.2	-1.8	0.5	1.1
Medication: Lansoprazole	0.6	0.7	1.8	-0.5	-0.8	-1.3	1.0	0.8	0.7	-0.7	-0.7	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.5	0.3	0.5	0.2	-0.9	1.6	1.0	1.1	-0.1	-0.5
Heart disease (mother)	0.6	0.7	1.8	-1.3	-0.1	0.4	-1.0	0.7	-1.0	0.8	-1.1	-0.3
Medication: Gliclazide	0.6	0.7	2.0	0.7	1.4	0.4	-0.5	0.8	0.2	1.4	0.7	-0.3
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.5	1.6	-0.4	-0.9	1.3	-0.0	1.1	0.5	0.6	0.6
Impedance of whole body	0.6	3.0	11.5	-1.6	-1.8	-2.5	1.0	0.0	1.2	-3.4	-0.7	-0.6
Vitamin and mineral supplements	0.5	0.7	2.5	-1.1	-0.5	-0.7	0.6	0.5	0.4	-0.4	-0.9	-1.6
Townsend deprivation index at recruitment	0.5	0.7	2.8	1.7	0.2	-0.5	0.3	0.4	1.2	-0.6	0.9	0.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.5	0.8	0.6	0.4	-0.3	-0.9	-0.1	-0.9	0.7	1.2
Waist circumference	0.5	1.8	5.3	0.5	-0.1	-0.5	0.7	2.2	0.4	2.3	-1.4	-1.6
Heart attack	0.5	0.6	2.8	1.7	0.4	-0.4	0.8	0.4	1.0	0.6	0.4	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.4	-1.6	-0.3	-0.8	0.3	-0.1	-0.0	-0.9	-0.5	-0.8
Mouth/teeth dental problems: Dentures	0.5	0.9	2.1	0.5	0.9	0.4	-0.4	-1.3	-0.3	-1.4	1.0	1.3
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.1	1.4	-0.2	-0.7	0.4	0.3	1.3	-0.3	0.4	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	1.8	1.3	1.2	0.7	-0.7	0.1	0.4	0.1	1.2	0.7
Health satisfaction	0.5	0.7	1.7	0.9	-0.4	-0.9	0.7	1.1	1.3	0.8	-0.4	0.1
Eye problems/disorders: None of the above	0.5	0.6	2.1	-0.5	-0.9	-1.0	0.5	-0.4	0.4	-1.5	-0.3	-0.7
Alcohol intake frequency.	0.5	1.1	2.7	-0.7	0.7	0.8	-1.0	-1.6	-1.6	-1.3	-0.1	0.7
Medication: Atorvastatin	0.5	0.6	1.8	0.1	0.3	0.6	-0.4	1.1	-0.4	1.3	-1.0	-0.6
Number of operations (self-reported)	0.5	0.7	2.6	0.3	0.2	-0.2	0.0	-0.9	0.4	-1.5	0.8	1.6
Ever depressed for a whole week	0.5	0.6	1.9	0.7	1.4	1.1	-0.8	-0.0	-0.5	0.2	0.7	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	-0.7	0.5	0.4	-0.6	-1.2	-0.9	-1.0	0.2	-0.9
Crohns Disease (2017)	0.4	0.9	3.4	-0.6	0.4	-0.2	1.1	1.3	0.5	1.8	0.1	-1.1
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.0	-1.0	-0.4	-1.2	1.3	0.8	-0.0	-0.2	-1.4	-0.3
Lung FEV1/FVC ratio	0.4	2.1	5.9	-2.4	-0.5	0.1	-1.1	-1.4	-1.6	-2.2	-1.4	-0.4
Average weekly spirits intake	0.4	0.5	2.1	1.4	0.2	0.6	0.1	0.0	-0.3	1.4	0.6	0.0
Medication: Co-codamol	0.4	0.5	1.4	1.1	-0.2	-0.5	0.9	-0.1	1.2	-0.4	-0.1	0.3
Worrier / anxious feelings	0.4	0.7	2.6	-1.1	-0.4	-0.8	-0.0	0.6	0.2	-1.0	-0.5	-1.6
Medication: Omeprazole	0.4	0.5	1.5	-0.2	0.5	0.6	-0.8	-1.2	-1.0	-0.7	0.5	-0.4
Number of full sisters	0.4	0.5	0.9	-0.3	0.0	0.9	-0.7	0.1	-0.9	1.0	-0.8	-0.8
Family relationship satisfaction	0.4	0.5	1.5	0.9	0.6	0.4	-0.7	0.2	0.4	0.1	1.0	1.2
Wears glasses or contact lenses	0.4	0.5	2.5	0.7	0.2	0.3	0.5	0.7	-0.1	1.6	-0.3	0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.6	-0.3	0.4	1.1	-1.0	0.1	-1.0	1.3	-0.1	0.4
Alcohol drinker status: Never	0.4	0.5	1.4	-0.7	-0.9	-0.5	-0.0	0.3	0.2	-0.3	-1.2	-1.2
Commuting to job workplace: Cycle	0.4	0.5	1.2	-0.2	-1.1	-0.2	0.5	0.7	-0.3	1.0	-1.0	-0.6
HbA1C	0.3	0.4	1.0	0.7	0.2	0.3	-0.5	-1.0	0.4	-0.6	1.0	-0.1
Blood Eosinophil Count	0.3	2.4	10.4	-3.2	-0.7	1.0	-1.4	-1.2	-1.3	-0.3	-1.8	-1.1
Allergy or Eczema	0.3	0.8	3.0	-1.7	-0.6	-0.7	0.2	-0.3	-0.1	-1.2	-1.1	-1.0
Medication: Metformin	0.3	0.5	1.3	-0.2	1.1	0.6	-0.5	0.5	-1.0	0.7	-0.8	-0.4
Hand grip strength (right)	0.3	0.9	2.7	1.6	0.6	1.3	-0.8	-0.5	-0.1	1.0	1.0	0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	-0.2	-0.4	-0.6	0.6	0.6	0.5	0.2	-0.3	-1.0
Hayfever, allergic rhinitis or eczema	0.3	0.8	2.4	-1.5	-0.7	-0.8	0.2	-0.3	-0.1	-1.2	-1.1	-0.7
Financial difficulties in last 2 years	0.3	0.3	0.8	0.5	-0.2	-0.7	0.7	0.7	0.9	0.0	0.5	-0.6
Diabetes (self-reported)	0.3	0.4	1.8	0.1	-0.4	-0.2	0.6	0.8	-0.2	0.6	-1.3	-0.2
Medication: Paracetamol	0.3	0.5	1.3	0.8	-0.2	-0.6	1.1	-1.1	0.4	-1.0	0.5	0.0
Worry too long after embarrassment	0.3	0.5	1.3	0.5	-0.4	-1.0	1.2	0.9	0.6	0.4	-0.0	-1.0
Emphysema/chronic bronchitis	0.3	0.3	0.9	0.5	0.8	0.4	-0.7	0.6	0.5	0.9	0.3	-0.3
Breast cancer (self-reported)	0.3	0.4	1.1	-0.3	0.6	0.6	-1.1	-0.4	-1.1	0.0	0.2	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.3	-1.2	-0.6	-0.4	0.3	-0.2	-0.8	-0.8	-0.6	0.0
Medication: Paracetamol	0.3	0.4	1.2	1.0	0.1	-0.2	0.9	-1.1	0.2	-0.6	0.5	0.5
Irritability	0.3	0.5	1.7	-0.1	-0.4	-0.9	0.6	-0.2	1.0	-1.3	-0.3	-0.6
Age at First Birth	0.2	0.2	0.7	-0.1	-0.8	-0.6	0.3	0.4	0.6	-0.2	-0.3	-0.6
Ulcerative Colitis	0.2	0.3	0.8	-0.6	-0.3	-0.6	0.3	0.9	0.7	0.4	-0.5	-0.2
Blood Red Count	0.2	1.7	4.8	0.2	-1.3	0.9	-0.9	-1.9	-2.2	-1.2	-0.3	1.4
Qualifications: CSEs or equivalent	0.2	0.2	0.8	-0.1	-0.0	-0.5	0.1	0.4	0.9	-0.1	-0.4	-0.8
Serious illness, injury or assault to yourself	0.2	0.2	0.7	-0.0	0.8	0.2	-0.5	-0.4	0.3	-0.4	0.6	0.1
Impedance of arm (left)	0.2	0.8	1.9	-0.9	-0.8	-1.4	0.5	1.0	0.5	-0.8	-0.8	-0.8
Wheeze or whistling in the chest in last year	0.2	0.4	1.1	1.1	0.4	-0.5	0.1	0.7	1.0	0.7	0.0	-0.4
Qualifications: College or University degree	0.2	0.6	1.6	1.1	-0.5	-0.3	0.8	-0.2	1.3	-0.0	1.1	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.5	0.6	-0.7	-0.2	-0.0	0.7	-0.0	0.7	-0.5	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.7	-0.5	-0.2	0.2	-0.6	0.8	-0.3	-0.6	-0.8	-0.2
Irritable Bowel Disease (IBD)	0.1	0.3	1.2	-0.2	0.6	-0.1	0.7	0.6	0.4	1.1	0.6	-0.1
Tanning	0.1	1.3	2.9	-0.8	1.7	1.5	-1.4	-0.4	-1.2	0.3	1.0	1.1
Allergy	0.1	0.3	0.7	0.7	0.5	0.5	0.3	0.3	-0.4	0.8	0.8	0.2
Impedance of arm (right)	0.1	0.7	1.9	-1.4	-0.5	-0.8	-0.1	0.6	-0.1	-1.3	-0.8	-0.8
Average weekly red wine intake	0.1	0.1	0.6	0.1	-0.7	0.1	-0.2	-0.3	-0.4	-0.1	-0.7	0.2
Diabetes diagnosed by doctor	0.1	0.2	0.6	0.8	0.6	0.1	0.4	0.1	-0.5	0.4	-0.4	0.7
Mineral and other dietary supplements	0.1	0.2	0.7	0.2	0.8	-0.0	0.3	-0.1	0.3	-0.0	0.2	-0.9
Ulcerative Colitis (UC)	0.0	0.1	0.3	-0.3	0.4	0.1	0.1	0.2	-0.1	0.5	0.2	0.2

Hub : Genes

DDB2

Models

Trait associations