[Hub]/) : Traits : Impedance of leg (right) : ← →

chr14:72,386,949-75,864,873

Best TWAS P=9.91e-12 · Best GWAS P=1.69e-08 conditioned to 2.81e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	The Cancer Genome Atlas	Thyroid Carcinoma	DPF3	0.10	0.02	blup	210	0.07	1.9e-07	4.8	6.8	9.9e-12	-0.04	0.19	0.79	TRUE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FAM161B	0.03	0.01	blup	57	0.02	9.5e-04	3.8	-5.4	5.2e-08	0.09	0.02	0.58	TRUE
14	GTEx	Testis	AREL1	0.20	0.14	enet	34	0.13	2.1e-06	3.6	5.1	3.1e-07	-0.04	0.89	0.06	TRUE
10	GTEx	Esophagus Mucosa	ZFYVE1	0.10	0.00	lasso	7	0.00	2.0e-01	-5.3	-6.5	9.7e-11	0.02	0.10	0.67	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	DCAF4	0.18	0.01	enet	10	0.06	3.0e-03	-5.3	-6.4	1.3e-10	-0.04	0.04	0.71	FALSE
13	GTEx	Spleen	DCAF4	0.47	0.12	enet	10	0.19	1.5e-05	-4.4	-6.3	3.9e-10	0.02	0.11	0.84	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DCAF4	0.04	0.02	blup	83	0.03	1.2e-04	-4.6	-6.1	8.3e-10	-0.01	0.03	0.93	FALSE
3	GTEx	Breast Mammary Tissue	DCAF4	0.24	0.10	lasso	6	0.18	1.2e-09	-4.4	-5.9	4.3e-09	0.01	0.17	0.81	FALSE
9	GTEx	Esophagus Mucosa	DCAF4	0.30	0.19	enet	35	0.23	1.3e-15	-5.3	-5.7	1.3e-08	-0.06	0.02	0.98	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RP4-647C14.3	0.25	0.11	lasso	6	0.13	7.3e-11	-4.9	5.6	1.9e-08	-0.02	0.11	0.88	FALSE
2	GTEx	Adipose Visceral Omentum	DCAF4	0.23	0.07	enet	30	0.13	4.3e-07	-4.3	-5.6	2.0e-08	-0.01	0.07	0.91	FALSE
6	GTEx	Colon Sigmoid	DCAF4	0.30	0.10	lasso	9	0.11	1.3e-04	-5.3	-5.6	2.0e-08	-0.01	0.03	0.80	FALSE
15	NTR	Blood	DCAF4	0.04	0.03	lasso	6	0.03	6.5e-09	-5.3	-5.6	2.1e-08	0.00	0.02	0.98	FALSE
11	GTEx	Skin Sun Exposed Lower leg	PAPLN	0.30	0.11	lasso	5	0.17	5.2e-14	-4.9	5.6	2.2e-08	-0.02	0.11	0.88	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	FAM161B	0.03	0.03	enet	5	0.03	4.9e-04	-4.8	-5.4	7.8e-08	0.10	0.01	0.88	FALSE
4	GTEx	Breast Mammary Tissue (Female)	DCAF4	0.16	0.07	lasso	4	0.03	4.4e-02	4.7	-5.3	1.3e-07	0.02	0.08	0.31	FALSE
1	GTEx	Adipose Subcutaneous	DCAF4	0.20	0.05	lasso	7	0.18	1.1e-14	-4.4	-5.2	1.7e-07	-0.04	0.07	0.93	FALSE
7	GTEx	Colon Transverse	DCAF4	0.26	0.27	lasso	10	0.27	2.7e-13	-4.4	-5.2	2.0e-07	0.00	0.27	0.72	FALSE
5	GTEx	Cells Transformed fibroblasts	DPF3	0.39	0.40	lasso	4	0.39	9.6e-31	-5.0	-5.1	2.6e-07	0.06	0.10	0.89	FALSE