[Hub]/) : Traits : Impedance of leg (right) : ← →

chr22:30,802,444-32,708,691

Best TWAS P=1.94e-09 · Best GWAS P=1.34e-08 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Gastroesophageal Junction SFI1 0.15 0.07 lasso 3 0.06 3.7e-03 -5.7 5.7 1.5e-08 -0.95 0.02 0.92 FALSE
2 GTEx Esophagus Muscularis LIMK2 0.08 0.03 lasso 4 0.01 4.3e-02 -5.7 5.5 3.6e-08 -0.99 0.02 0.95 FALSE
3 GTEx Esophagus Muscularis SFI1 0.22 0.13 enet 20 0.15 3.7e-09 -4.4 5.4 5.6e-08 -0.83 0.09 0.91 FALSE
4 GTEx Muscle Skeletal SFI1 0.13 0.09 enet 22 0.10 1.7e-10 4.4 6.0 1.9e-09 -0.79 0.55 0.43 TRUE
5 GTEx Pancreas SELM 0.29 0.23 enet 18 0.30 5.2e-13 4.2 5.2 2.5e-07 -0.59 0.57 0.41 FALSE
6 GTEx Thyroid SFI1 0.12 0.10 lasso 12 0.11 1.4e-08 -5.1 5.5 4.2e-08 -0.68 0.17 0.82 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma LIMK2 0.06 0.06 blup 47 0.06 9.3e-08 -4.8 5.4 6.4e-08 -0.81 0.03 0.96 FALSE
8 The Cancer Genome Atlas Rectum Adenocarcinoma RNF185 0.18 0.10 enet 6 0.12 9.7e-04 -5.0 -5.4 7.0e-08 0.83 0.01 0.69 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma RNF185 0.06 0.09 lasso 4 0.07 1.5e-07 -5.4 -5.4 7.1e-08 0.85 0.01 0.99 FALSE