[Hub]/) : Traits : Impedance of leg (right) :

chr22:40,195,017-42,269,532

Best TWAS P=1.74e-15 · Best GWAS P=2.61e-16 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EP300 0.05 0.00 bslmm 289 0.02 0.00319 -4.3 5.6 1.9e-08 0.16 0.44 0.06 TRUE
2 GTEx Brain Frontal Cortex BA9 SLC25A17 0.11 -0.01 lasso 5 0.00 0.34900 4.3 5.7 1.2e-08 0.35 0.08 0.16 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma TNRC6B 0.02 0.01 blup 92 0.01 0.00266 6.1 7.3 4.1e-13 0.85 0.02 0.82 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma MKL1 0.05 0.03 blup 105 0.04 0.00386 5.0 6.0 2.3e-09 0.38 0.04 0.18 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADSL 0.04 0.03 enet 6 0.03 0.00016 8.2 7.5 5.0e-14 0.90 0.00 0.94 FALSE
6 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ADSL 0.07 0.02 blup 33 0.05 0.00052 2.9 5.7 1.4e-08 0.68 0.07 0.50 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma ADSL 0.03 0.00 blup 33 0.01 0.00894 8.0 7.4 1.5e-13 0.84 0.01 0.60 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ADSL 0.06 0.02 lasso 2 0.03 0.00665 8.1 8.0 1.7e-15 0.97 0.00 0.83 TRUE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma ADSL 0.09 0.03 lasso 3 0.01 0.07710 8.1 7.7 1.5e-14 0.92 0.00 0.76 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma ADSL 0.04 0.00 blup 33 0.03 0.00260 3.2 5.9 3.2e-09 0.68 0.02 0.71 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma MKL1 0.05 0.01 blup 95 0.02 0.02200 -6.4 6.6 4.6e-11 0.47 0.03 0.79 FALSE