[Hub]/) : Traits : Impedance of leg (left) : ← →

chr8:37,329,315-38,989,813

Best TWAS P=1.69e-10 · Best GWAS P=2.03e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Breast Mammary Tissue (Female)	RP11-350N15.5	0.12	0.10	lasso	2	0.07	3.9e-03	6.3	-6.4	1.7e-10	-0.99	0.02	0.89	TRUE
2	GTEx	Adrenal Gland	DDHD2	0.25	0.21	lasso	2	0.19	1.7e-07	6.3	6.4	1.8e-10	0.99	0.02	0.97	FALSE
12	GTEx	Spleen	DDHD2	0.17	0.17	lasso	2	0.11	7.8e-04	6.3	6.3	2.8e-10	1.00	0.03	0.90	FALSE
8	GTEx	Liver	DDHD2	0.29	0.01	lasso	5	-0.01	5.4e-01	6.3	6.2	4.1e-10	0.90	0.03	0.69	FALSE
3	GTEx	Artery Tibial	DDHD2	0.07	0.07	lasso	2	0.05	7.3e-05	6.2	6.2	4.3e-10	1.00	0.02	0.98	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	RPS20P22	0.04	0.00	blup	267	0.02	2.9e-03	6.3	6.2	5.7e-10	0.76	0.02	0.87	FALSE
15	GTEx	Thyroid	RP11-90P5.2	0.09	0.00	enet	12	0.01	1.1e-01	6.0	-6.2	6.3e-10	-0.83	0.07	0.72	FALSE
4	GTEx	Breast Mammary Tissue	RP11-350N15.5	0.08	0.03	enet	12	0.02	1.9e-02	4.6	-6.2	7.4e-10	-0.90	0.02	0.93	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DDHD2	0.04	0.04	bslmm	286	0.04	2.0e-05	6.1	6.1	8.7e-10	0.94	0.03	0.97	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	DDHD2	0.11	0.08	lasso	3	0.08	1.9e-08	6.1	6.1	9.1e-10	0.97	0.03	0.97	FALSE
6	GTEx	Colon Sigmoid	DDHD2	0.15	0.15	lasso	3	0.12	7.5e-05	6.1	6.1	9.9e-10	0.97	0.04	0.91	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	PPAPDC1B	0.06	0.08	enet	14	0.09	4.0e-11	6.3	6.1	1.1e-09	0.99	0.03	0.97	FALSE
21	YFS	Blood	LSM1	0.02	0.00	bslmm	218	0.01	4.1e-04	4.1	-6.1	1.1e-09	-0.84	0.04	0.94	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DDHD2	0.03	0.03	blup	21	0.03	3.5e-04	5.6	6.1	1.1e-09	0.99	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPAPDC1B	0.02	0.00	blup	18	0.01	4.2e-02	6.2	6.1	1.1e-09	0.97	0.01	0.54	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	DDHD2	0.02	0.01	blup	21	0.01	2.4e-02	6.3	6.1	1.3e-09	0.99	0.01	0.78	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	DDHD2	0.01	0.01	blup	21	0.01	2.3e-03	6.2	6.0	1.7e-09	0.98	0.02	0.76	FALSE
20	YFS	Blood	BAG4	0.01	0.01	bslmm	234	0.00	2.6e-02	4.8	5.9	3.0e-09	0.84	0.06	0.73	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DDHD2	0.07	0.05	blup	21	0.05	2.7e-03	6.1	5.8	5.7e-09	0.98	0.02	0.67	FALSE
16	NTR	Blood	BAG4	0.01	0.01	blup	253	0.01	3.9e-03	5.3	-5.7	1.2e-08	-0.95	0.05	0.93	FALSE
10	GTEx	Pituitary	DDHD2	0.25	0.22	lasso	3	0.17	3.9e-05	6.3	5.7	1.3e-08	0.94	0.02	0.93	FALSE
13	GTEx	Stomach	DDHD2	0.13	0.06	lasso	2	0.06	1.1e-03	5.7	5.7	1.5e-08	0.97	0.04	0.88	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	LSM1	0.09	0.16	lasso	6	0.16	7.3e-20	5.3	-5.4	5.7e-08	-0.96	0.31	0.69	FALSE
14	GTEx	Thyroid	DDHD2	0.11	0.10	lasso	4	0.09	3.8e-07	5.3	5.4	7.7e-08	0.95	0.04	0.96	FALSE
11	GTEx	Prostate	DDHD2	0.38	0.18	lasso	7	0.17	5.4e-05	5.3	5.4	7.9e-08	0.95	0.10	0.89	FALSE
9	GTEx	Nerve Tibial	DDHD2	0.15	0.16	enet	26	0.16	2.3e-11	6.1	5.3	8.6e-08	0.92	0.04	0.96	FALSE
7	GTEx	Esophagus Muscularis	DDHD2	0.12	0.13	lasso	2	0.12	5.7e-08	5.3	5.2	1.5e-07	0.95	0.04	0.96	FALSE