[Hub]/) : Traits : Impedance of leg (left) : ← →

chr11:45,945,837-48,485,877

Best TWAS P=1.9e-10 · Best GWAS P=2.1e-11 conditioned to 0.374

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta MADD 0.09 0.03 enet 22 0.04 1.9e-03 6.3 -5.2 1.7e-07 -0.64 0.06 0.60 TRUE
2 GTEx Brain Cerebellar Hemisphere RP11-750H9.5 0.17 0.25 lasso 6 0.21 3.5e-06 5.6 -5.6 2.2e-08 -0.80 0.30 0.35 FALSE
3 GTEx Esophagus Mucosa MADD 0.27 0.04 enet 18 0.12 4.1e-08 2.8 -5.4 8.7e-08 -0.54 0.20 0.30 TRUE
4 GTEx Esophagus Muscularis MADD 0.13 0.07 enet 8 0.11 2.0e-07 2.5 -5.2 2.4e-07 -0.65 0.48 0.36 FALSE
5 GTEx Liver C1QTNF4 0.25 0.14 enet 16 0.20 2.3e-06 -3.4 6.0 1.6e-09 0.82 0.06 0.90 FALSE
6 GTEx Nerve Tibial NR1H3 0.10 0.00 enet 24 0.08 4.7e-06 4.5 6.4 1.9e-10 0.40 0.06 0.32 TRUE
7 GTEx Nerve Tibial CELF1 0.08 0.02 enet 15 0.06 4.3e-05 6.0 -6.1 1.1e-09 -0.79 0.03 0.87 FALSE
8 GTEx Pituitary MADD 0.42 0.32 lasso 6 0.39 8.9e-11 5.2 -5.2 2.6e-07 -0.74 0.36 0.47 FALSE
9 GTEx Thyroid MADD 0.11 0.00 enet 13 0.01 6.1e-02 -3.8 -5.6 2.0e-08 -0.43 0.06 0.16 FALSE
10 NTR Blood MADD 0.01 0.01 enet 8 0.01 4.7e-03 -3.8 -5.9 2.7e-09 -0.44 0.15 0.14 FALSE
11 ROSMAP Brain Pre-frontal Cortex ATG13 0.05 0.02 bslmm 266 0.03 1.3e-04 -3.8 5.6 2.2e-08 0.35 0.07 0.84 FALSE
12 YFS Blood FNBP4 0.02 0.01 bslmm 301 0.01 8.9e-05 6.6 -5.8 6.3e-09 -0.74 0.01 0.98 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma MADD 0.11 0.03 enet 14 0.06 1.4e-11 2.5 -5.3 1.2e-07 -0.49 0.53 0.36 FALSE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MADD 0.16 0.05 blup 64 0.08 2.2e-09 -3.9 -5.3 1.2e-07 -0.30 0.69 0.21 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma MADD 0.15 0.04 enet 10 0.06 4.5e-07 2.5 -5.2 2.6e-07 -0.40 0.17 0.06 FALSE