[Hub]/) : Traits : Impedance of leg (left) : ← →

chr11:45,945,837-48,485,877

Best TWAS P=1.9e-10 · Best GWAS P=2.1e-11 conditioned to 0.374

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Nerve Tibial	NR1H3	0.10	0.00	enet	24	0.08	4.7e-06	4.5	6.4	1.9e-10	0.40	0.06	0.32	TRUE
3	GTEx	Esophagus Mucosa	MADD	0.27	0.04	enet	18	0.12	4.1e-08	2.8	-5.4	8.7e-08	-0.54	0.20	0.30	TRUE
1	GTEx	Artery Aorta	MADD	0.09	0.03	enet	22	0.04	1.9e-03	6.3	-5.2	1.7e-07	-0.64	0.06	0.60	TRUE
7	GTEx	Nerve Tibial	CELF1	0.08	0.02	enet	15	0.06	4.3e-05	6.0	-6.1	1.1e-09	-0.79	0.03	0.87	FALSE
5	GTEx	Liver	C1QTNF4	0.25	0.14	enet	16	0.20	2.3e-06	-3.4	6.0	1.6e-09	0.82	0.06	0.90	FALSE
10	NTR	Blood	MADD	0.01	0.01	enet	8	0.01	4.7e-03	-3.8	-5.9	2.7e-09	-0.44	0.15	0.14	FALSE
12	YFS	Blood	FNBP4	0.02	0.01	bslmm	301	0.01	8.9e-05	6.6	-5.8	6.3e-09	-0.74	0.01	0.98	FALSE
9	GTEx	Thyroid	MADD	0.11	0.00	enet	13	0.01	6.1e-02	-3.8	-5.6	2.0e-08	-0.43	0.06	0.16	FALSE
2	GTEx	Brain Cerebellar Hemisphere	RP11-750H9.5	0.17	0.25	lasso	6	0.21	3.5e-06	5.6	-5.6	2.2e-08	-0.80	0.30	0.35	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	ATG13	0.05	0.02	bslmm	266	0.03	1.3e-04	-3.8	5.6	2.2e-08	0.35	0.07	0.84	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	MADD	0.11	0.03	enet	14	0.06	1.4e-11	2.5	-5.3	1.2e-07	-0.49	0.53	0.36	FALSE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MADD	0.16	0.05	blup	64	0.08	2.2e-09	-3.9	-5.3	1.2e-07	-0.30	0.69	0.21	FALSE
4	GTEx	Esophagus Muscularis	MADD	0.13	0.07	enet	8	0.11	2.0e-07	2.5	-5.2	2.4e-07	-0.65	0.48	0.36	FALSE
8	GTEx	Pituitary	MADD	0.42	0.32	lasso	6	0.39	8.9e-11	5.2	-5.2	2.6e-07	-0.74	0.36	0.47	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	MADD	0.15	0.04	enet	10	0.06	4.5e-07	2.5	-5.2	2.6e-07	-0.40	0.17	0.06	FALSE