Best TWAS P=1.65e-09 · Best GWAS P=4.05e-09 conditioned to 1.53e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | GTEx | Nerve Tibial | EHD4 | 0.20 | 0.04 | lasso | 7 | 0.08 | 2.4e-06 | 3.6 | -6.0 | 1.7e-09 | 0.13 | 0.59 | 0.38 | TRUE |
| 1 | GTEx | Artery Coronary | CATSPER2 | 0.81 | 0.14 | lasso | 12 | 0.03 | 3.0e-02 | 4.9 | -5.7 | 1.4e-08 | -0.02 | 0.08 | 0.61 | TRUE |
| 6 | GTEx | Thyroid | RP11-23P13.6 | 0.07 | 0.00 | lasso | 5 | 0.01 | 9.6e-02 | 3.8 | -5.7 | 1.2e-08 | 0.66 | 0.05 | 0.50 | FALSE |
| 7 | GTEx | Thyroid | PLA2G4B | 0.14 | 0.09 | enet | 11 | 0.08 | 1.6e-06 | 4.5 | 5.5 | 3.9e-08 | -0.19 | 0.92 | 0.07 | FALSE |
| 2 | GTEx | Artery Tibial | EHD4 | 0.14 | 0.03 | enet | 21 | 0.06 | 1.0e-05 | 4.1 | -5.3 | 1.2e-07 | 0.19 | 0.77 | 0.05 | FALSE |
| 3 | GTEx | Artery Tibial | LCMT2 | 0.25 | 0.03 | enet | 33 | 0.08 | 6.5e-07 | 3.5 | -5.2 | 1.9e-07 | 0.00 | 0.20 | 0.46 | FALSE |
| 4 | GTEx | Brain Cerebellum | MAPKBP1 | 0.23 | 0.09 | lasso | 8 | 0.12 | 2.2e-04 | 4.4 | -5.2 | 2.0e-07 | 0.16 | 0.41 | 0.07 | FALSE |