[Hub]/) : Traits : Impedance of leg (left) : ← →

chr6:87,167,376-89,108,830

Best TWAS P=2.01e-12 · Best GWAS P=8.61e-13 conditioned to 0.0208

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ZNF292	0.04	0.05	lasso	12	0.03	4.1e-05	6.1	-6.2	5.9e-10	0.59	0.55	0.44	FALSE
2	GTEx	Artery Aorta	RP11-393I2.4	0.10	0.03	lasso	5	0.02	2.4e-02	4.7	-5.4	5.2e-08	0.63	0.13	0.77	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	C6orf163	0.18	0.14	lasso	4	0.15	1.5e-05	5.4	5.4	7.5e-08	-0.59	0.60	0.14	FALSE
4	GTEx	Cells Transformed fibroblasts	SMIM8	0.18	0.14	lasso	5	0.12	1.4e-09	5.4	-5.4	6.1e-08	0.59	1.00	0.00	FALSE
5	GTEx	Cells Transformed fibroblasts	C6orf163	0.16	0.14	lasso	3	0.18	2.7e-13	5.3	5.5	4.5e-08	-0.56	1.00	0.00	FALSE
6	GTEx	Nerve Tibial	ZNF292	0.09	0.07	enet	16	0.10	1.5e-07	-6.6	-6.3	2.6e-10	0.72	0.65	0.35	FALSE
7	GTEx	Nerve Tibial	RP11-393I2.4	0.08	0.09	enet	18	0.09	6.8e-07	5.0	-5.9	4.4e-09	0.65	0.71	0.28	FALSE
8	GTEx	Stomach	C6orf163	0.10	0.06	lasso	1	0.05	2.3e-03	5.4	5.4	7.3e-08	-0.59	0.33	0.08	FALSE
9	METSIM	Adipose	AKIRIN2	0.04	0.03	lasso	3	0.02	6.3e-04	4.7	-5.2	2.3e-07	0.48	0.26	0.55	FALSE
10	METSIM	Adipose	C6orf164	0.05	0.06	lasso	8	0.06	9.3e-10	5.3	5.3	1.3e-07	-0.61	0.99	0.01	FALSE
11	NTR	Blood	C6orf162	0.02	0.02	blup	411	0.02	1.7e-08	-6.8	5.2	1.6e-07	-0.60	0.34	0.66	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	SMIM8	0.21	0.33	enet	34	0.38	3.9e-52	-6.5	6.2	7.7e-10	-0.62	0.27	0.73	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	SLC35A1	0.30	0.48	enet	25	0.50	5.7e-73	-7.0	-6.8	1.1e-11	0.95	0.02	0.98	FALSE
14	ROSMAP	Brain Pre-frontal Cortex	C6orf163	0.07	0.03	enet	16	0.06	9.1e-09	2.6	-5.6	2.8e-08	0.52	0.85	0.15	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf164	0.06	0.05	blup	94	0.06	1.0e-11	-6.2	6.6	5.3e-11	-0.58	0.03	0.97	FALSE
16	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C6orf164	0.07	0.06	blup	95	0.05	2.0e-03	-6.7	6.6	3.7e-11	-0.72	0.02	0.96	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	C6orf164	0.05	0.02	enet	8	0.02	1.9e-02	-6.6	6.5	6.0e-11	-0.67	0.02	0.76	FALSE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf164	0.06	0.08	blup	94	0.08	8.3e-09	-6.6	6.9	5.1e-12	-0.69	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SLC35A1	0.02	0.01	blup	72	0.00	8.7e-02	-7.0	7.0	2.0e-12	-0.84	0.01	0.91	TRUE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf164	0.11	0.12	blup	95	0.14	5.0e-15	-6.6	6.3	3.5e-10	-0.64	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf164	0.11	0.14	enet	8	0.12	1.6e-07	-6.5	6.7	2.3e-11	-0.68	0.01	0.99	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf164	0.04	0.02	blup	95	0.04	5.4e-05	5.4	6.7	1.5e-11	-0.71	0.03	0.97	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf164	0.09	0.12	blup	95	0.11	4.1e-13	-6.5	6.3	2.4e-10	-0.71	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C6orf164	0.06	0.06	lasso	4	0.07	4.6e-08	-6.7	6.7	2.3e-11	-0.67	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf163	0.06	0.02	blup	66	0.02	1.1e-02	5.4	6.1	8.1e-10	-0.65	0.07	0.63	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf164	0.12	0.12	blup	95	0.14	7.4e-10	-6.0	6.5	7.1e-11	-0.73	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC35A1	0.04	0.03	lasso	5	0.02	1.3e-02	-7.0	7.0	2.5e-12	-0.94	0.01	0.91	FALSE
28	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf164	0.07	0.11	enet	8	0.10	8.4e-05	-6.7	6.5	6.7e-11	-0.68	0.01	0.97	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	C6orf164	0.13	0.10	blup	95	0.11	1.5e-11	-6.6	5.9	4.5e-09	-0.58	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC35A1	0.05	0.03	blup	72	0.05	6.8e-06	4.5	5.2	1.6e-07	-0.53	0.82	0.16	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf164	0.17	0.13	lasso	4	0.10	6.2e-08	-6.7	6.5	6.8e-11	-0.67	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C6orf164	0.12	0.08	enet	9	0.09	5.6e-04	4.3	6.0	2.7e-09	-0.60	0.03	0.90	FALSE
33	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SLC35A1	0.14	0.04	blup	72	0.07	1.4e-03	-3.4	6.2	6.4e-10	-0.78	0.01	0.82	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf164	0.18	0.24	lasso	4	0.25	1.4e-24	-6.5	6.6	3.6e-11	-0.68	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	SLC35A1	0.08	0.07	enet	17	0.07	5.0e-07	-7.0	-6.6	5.4e-11	0.91	0.01	0.99	FALSE