TWAS hub - C6orf164

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0630	0.0260	4.6e-05	0.015	0.035	0.014	0.033	0.016	5.7e-03	4.2e-05	6.2e-03	6.8e-05	4.3e-03
2	METSIM	Adipose	0.0528	0.0206	1.9e-08	0.064	0.053	0.058	0.051	0.063	7.2e-10	1.9e-08	4.8e-09	4.3e-08	9.3e-10
3	TCGA	Bladder Urothelial Carcinoma	0.0940	0.0570	2.7e-03	-0.002	0.000	0.001	NA	-0.003	6.1e-01	2.9e-01	2.8e-01	NA	7.8e-01
4	TCGA	Breast Invasive Carcinoma	0.0618	0.0287	6.2e-11	0.054	0.057	0.050	NA	0.046	3.2e-11	1.0e-11	1.7e-10	NA	9.7e-10
5	TCGA	Cervical Squamous Cell Carcinoma	0.0670	0.0360	6.0e-04	0.058	0.049	0.027	NA	0.041	8.2e-04	2.0e-03	1.7e-02	NA	4.1e-03
6	TCGA	Colon Adenocarcinoma	0.0450	0.0300	8.2e-03	0.020	0.008	0.022	NA	0.007	2.4e-02	1.0e-01	1.9e-02	NA	1.2e-01
7	TCGA	Esophageal Carcinoma	0.1540	0.0940	2.6e-03	0.069	0.038	0.043	NA	-0.001	3.3e-03	2.3e-02	1.7e-02	NA	3.4e-01
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0593	0.0278	2.4e-08	0.077	0.075	0.067	NA	0.075	4.9e-09	8.3e-09	5.1e-08	NA	9.2e-09
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.1095	0.0463	7.0e-13	0.121	0.136	0.123	NA	0.129	1.7e-13	5.0e-15	1.1e-13	NA	2.7e-14
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1070	0.0520	1.4e-06	0.135	0.116	0.123	NA	0.121	3.8e-08	3.6e-07	1.6e-07	NA	2.0e-07
11	TCGA	Brain Lower Grade Glioma	0.0369	0.0181	7.7e-06	0.020	0.036	0.028	NA	0.019	2.1e-03	5.4e-05	3.4e-04	NA	3.0e-03
12	TCGA	Lung Adenocarcinoma	0.0882	0.0375	1.4e-12	0.117	0.113	0.107	NA	0.107	1.6e-13	4.1e-13	1.6e-12	NA	1.6e-12
13	TCGA	Lung Squamous Cell Carcinoma	0.0583	0.0260	9.4e-08	0.064	0.057	0.061	NA	0.067	7.9e-08	4.2e-07	1.8e-07	NA	4.6e-08
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.1250	0.0480	1.8e-09	0.117	0.142	0.124	NA	0.118	2.9e-08	7.4e-10	9.7e-09	NA	2.2e-08
15	TCGA	Pancreatic Adenocarcinoma	0.0720	0.0380	9.9e-04	0.107	0.088	0.095	NA	0.093	3.2e-05	1.6e-04	8.4e-05	NA	1.0e-04
16	TCGA	Prostate Adenocarcinoma	0.1328	0.0522	3.7e-11	0.100	0.110	0.095	NA	0.096	1.4e-10	1.5e-11	3.7e-10	NA	3.1e-10
17	TCGA	Stomach Adenocarcinoma	0.1670	0.0790	2.5e-08	0.132	0.080	0.099	NA	0.104	9.3e-10	2.0e-06	1.2e-07	NA	6.2e-08
18	TCGA	Testicular Germ Cell Tumors	0.1230	0.0600	3.2e-04	0.084	0.079	0.087	NA	0.063	6.8e-04	9.6e-04	5.6e-04	NA	2.9e-03
19	TCGA	Thyroid Carcinoma	0.1770	0.0610	0.0e+00	0.244	0.250	0.246	NA	0.254	1.3e-23	3.3e-24	9.0e-24	NA	1.3e-24

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Blood White Count	8.5	62.7	82.9	-5.3	-8.4	-4.6	-8.1	-8.7	-8.9	-7.5	-8.1	-7.4	-8.8	-9.1	-8.5	-8.1	-8.4	-8.8	-6.5	-8.0	-6.8	-8.6
Impedance of leg (right)	7.9	38.2	48.6	1.0	5.3	4.9	6.5	6.8	6.6	5.1	7.0	6.2	6.7	6.7	6.5	6.7	6.8	6.5	6.2	6.7	5.9	6.6
Impedance of leg (left)	7.7	37.3	47.6	1.1	5.3	4.7	6.6	6.6	6.5	5.0	6.9	6.3	6.7	6.7	6.3	6.7	6.5	6.5	5.9	6.5	6.0	6.6
Medication: Aspirin	6.0	7.9	10.2	-1.2	-2.6	-2.4	-3.0	-3.0	-3.1	-2.2	-2.8	-2.8	-3.1	-2.9	-3.2	-3.0	-2.9	-3.2	-2.5	-3.0	-2.6	-3.1
Guilty feelings	6.0	9.0	11.9	0.0	-2.4	-2.6	-3.5	-3.3	-3.2	-1.9	-3.4	-3.2	-3.2	-3.1	-3.2	-3.4	-3.1	-3.3	-2.6	-3.2	-3.2	-3.2
Impedance of whole body	5.9	30.0	40.3	1.4	5.3	3.8	5.8	6.1	5.8	4.3	6.1	5.5	6.1	6.3	5.8	5.9	5.9	5.8	5.0	5.9	5.0	6.0
Hypothyroidism (self reported)	5.7	13.0	17.2	-0.3	2.3	4.2	3.7	3.6	4.0	3.1	4.0	3.7	3.8	3.1	3.6	4.0	3.7	4.0	3.9	4.1	3.6	3.9
Relative age voice broke	5.7	8.7	14.3	1.0	3.0	1.3	3.4	2.8	3.6	2.3	3.1	3.1	3.8	3.6	3.0	3.4	2.3	3.7	1.4	2.8	2.6	3.6
Impedance of arm (right)	5.7	26.5	36.9	2.2	5.5	3.4	5.1	5.7	5.4	4.3	5.4	5.0	5.9	6.1	5.5	5.4	5.5	5.5	4.7	5.6	4.2	5.7
Birth weight	5.7	12.5	17.6	1.1	-2.1	-4.1	-4.0	-3.2	-3.9	-2.6	-4.2	-3.9	-3.7	-3.0	-3.5	-4.1	-3.2	-3.9	-3.4	-3.8	-3.9	-3.8
Risk taking	5.6	8.2	10.9	-0.5	-2.6	-2.5	-3.1	-2.9	-3.1	-2.8	-2.9	-3.3	-3.3	-3.1	-2.7	-3.1	-2.6	-3.2	-2.3	-3.1	-2.7	-3.2
Ever taken oral contraceptive pill	5.2	5.8	7.7	0.3	-1.7	-2.6	-2.6	-2.4	-2.6	-2.0	-2.8	-2.6	-2.5	-2.3	-2.3	-2.7	-2.5	-2.7	-2.3	-2.5	-2.6	-2.5
Ever had stillbirth, spontaneous miscarriage or termination	4.9	5.2	7.5	-1.8	-2.7	-1.7	-2.2	-2.6	-2.2	-2.7	-2.0	-2.1	-2.5	-2.7	-2.1	-2.0	-2.4	-2.2	-2.5	-2.6	-1.7	-2.3
Hypothyroidism/myxoedema (self-reported)	4.8	9.4	16.7	-1.2	1.5	4.1	3.3	3.0	3.2	2.6	3.5	3.2	2.9	2.4	2.8	3.3	3.2	3.0	3.8	3.5	3.3	3.1
Blood Eosinophil Count	4.7	36.1	47.5	1.8	6.3	4.2	5.7	6.7	6.4	5.8	6.4	6.1	6.6	6.6	6.9	6.3	6.5	6.5	5.0	6.3	5.4	6.6
Illnesses of father: High blood pressure	4.7	5.8	9.1	-0.7	-2.2	-1.5	-3.0	-2.4	-2.5	-2.2	-2.5	-3.0	-2.6	-2.7	-2.2	-2.6	-2.3	-2.4	-2.2	-2.1	-2.7	-2.6
Heart attack/myocardial infarction (self-reported)	4.7	6.1	7.8	-0.8	-2.2	-2.0	-2.8	-2.6	-2.6	-2.4	-2.5	-2.3	-2.6	-2.6	-2.6	-2.6	-2.5	-2.8	-2.3	-2.6	-2.6	-2.6
Medication: Aspirin	4.5	5.9	8.0	-1.6	-2.3	-2.1	-2.4	-2.6	-2.7	-2.1	-2.3	-2.3	-2.7	-2.4	-2.8	-2.6	-2.5	-2.7	-2.3	-2.7	-2.0	-2.7
High blood pressure (siblings)	4.4	6.4	9.5	0.3	-1.8	-2.2	-2.7	-2.8	-2.5	-2.7	-2.7	-2.7	-2.4	-2.6	-2.6	-2.6	-2.9	-2.4	-3.1	-2.6	-2.8	-2.5
Allergy or Eczema	4.3	11.2	21.6	4.0	4.7	1.6	2.5	3.7	3.5	3.3	2.9	2.6	3.9	4.1	3.9	3.0	3.4	3.8	1.8	3.6	1.9	3.8
Allergy	4.3	9.8	12.7	-2.2	-3.5	-2.2	-2.8	-3.4	-3.4	-3.3	-3.0	-2.9	-3.6	-3.5	-3.5	-3.1	-3.2	-3.5	-2.4	-3.5	-2.3	-3.5
Heart attack	4.2	5.3	6.8	-1.1	-2.2	-1.6	-2.5	-2.5	-2.5	-2.4	-2.3	-2.1	-2.5	-2.6	-2.5	-2.4	-2.4	-2.6	-2.1	-2.5	-2.2	-2.5
Supplements: Fish oil (including cod liver oil)	4.2	5.4	11.0	1.8	-0.8	-2.6	-2.4	-2.4	-2.0	-1.4	-3.0	-3.0	-2.1	-2.1	-2.1	-2.8	-2.4	-2.1	-2.2	-2.4	-3.3	-2.3
Hayfever, allergic rhinitis or eczema	4.0	8.6	12.3	2.4	3.5	1.9	2.5	3.3	3.1	3.2	2.8	2.6	3.4	3.4	3.2	2.9	3.0	3.3	2.1	3.3	2.1	3.3
Medication: Seretide 50 evohaler	3.8	4.3	7.5	0.0	1.7	2.7	1.8	2.0	2.4	1.6	2.2	2.0	2.3	1.6	2.4	2.2	2.1	2.4	2.1	2.7	1.5	2.4
Mineral and other dietary supplements	3.8	5.1	8.3	-0.8	1.2	2.9	2.2	2.2	2.2	1.8	2.5	2.8	2.3	1.9	2.2	2.6	2.2	2.3	2.2	2.6	2.7	2.4
Lung FVC	3.7	18.6	23.9	0.6	-3.0	-4.8	-4.3	-4.3	-4.5	-4.2	-4.6	-4.8	-4.6	-3.9	-4.2	-4.9	-4.1	-4.7	-4.3	-4.9	-4.5	-4.7
Impedance of arm (left)	3.5	16.2	23.7	1.7	4.5	2.5	3.9	4.6	4.1	3.2	4.3	3.9	4.6	4.9	4.4	4.2	4.4	4.2	3.5	4.4	3.3	4.5
Medication: Levothyroxine sodium	3.4	5.7	13.2	-1.3	1.1	3.6	2.6	2.2	2.4	2.1	2.5	2.3	2.3	1.6	2.2	2.5	2.2	2.5	3.1	3.0	2.2	2.4
Falls in the last year	3.3	4.5	7.8	-2.8	-2.4	-1.7	-1.9	-2.0	-2.6	-2.1	-1.7	-1.8	-2.5	-1.9	-2.4	-2.1	-1.6	-2.6	-1.6	-2.4	-1.0	-2.4
Hayfever/allergic rhinitis (self-reported)	3.2	4.2	7.1	1.6	2.7	0.9	1.9	2.2	2.2	2.2	1.9	1.8	2.5	2.5	2.1	2.1	1.9	2.4	1.1	2.2	1.4	2.4
Leg fat-free mass (right)	3.2	17.1	24.6	0.3	-3.0	-3.4	-4.6	-4.3	-4.4	-2.8	-5.0	-4.4	-4.4	-4.3	-4.3	-4.7	-4.4	-4.4	-4.2	-4.3	-4.3	-4.4
Leg predicted mass (right)	3.2	17.2	24.8	0.3	-3.1	-3.4	-4.6	-4.4	-4.4	-2.8	-5.0	-4.4	-4.4	-4.4	-4.3	-4.7	-4.5	-4.4	-4.2	-4.3	-4.4	-4.4
Medication: Ramipril	3.1	4.0	6.7	-1.8	-2.6	-1.1	-2.0	-2.1	-2.4	-1.6	-1.6	-1.9	-2.5	-2.4	-2.1	-1.9	-1.8	-2.3	-1.4	-2.3	-1.1	-2.4
Asthma (self-reported)	3.1	6.2	9.2	1.3	2.6	1.9	2.1	2.5	2.9	3.0	2.5	2.4	2.9	2.4	2.9	2.6	2.3	3.0	1.6	2.7	1.8	2.9
Vitamin and mineral supplements	3.0	4.1	7.0	-1.4	1.1	1.8	2.3	2.0	2.2	1.6	2.4	2.4	2.0	1.8	2.0	2.4	1.9	2.2	1.9	2.0	2.6	2.0
Qualifications: College or University degree	3.0	9.4	20.3	3.5	-0.1	-3.8	-3.5	-2.6	-2.9	-1.4	-4.0	-3.7	-2.4	-2.1	-2.3	-3.6	-3.0	-2.7	-3.6	-2.8	-4.5	-2.7
Major Depression (MDD)	2.9	3.6	5.4	0.2	-1.4	-1.2	-2.1	-2.1	-1.9	-1.6	-2.2	-2.0	-2.0	-2.1	-1.7	-2.0	-2.3	-1.6	-2.1	-1.9	-2.2	-1.9
Health satisfaction	2.9	3.7	6.1	-0.6	1.2	2.0	1.6	2.2	1.8	2.0	2.3	2.0	1.7	1.6	2.4	2.0	2.5	1.9	1.9	1.9	2.1	1.9
Multivitamins +/- minerals	2.8	3.5	5.0	0.9	-1.3	-1.9	-2.2	-1.9	-2.0	-1.4	-2.0	-2.1	-2.0	-1.7	-1.8	-2.2	-1.8	-2.1	-1.8	-2.1	-2.2	-1.9
Fractured/broken bones in last 5 years	2.8	3.6	5.2	-0.6	1.2	1.4	1.9	2.0	2.1	1.3	2.3	2.1	2.0	1.9	1.9	2.3	2.2	2.0	1.9	1.7	2.3	2.1
Alcohol intake versus 10 years previously	2.7	4.0	6.3	0.6	2.3	1.6	1.8	2.1	2.1	1.8	2.0	2.1	2.3	2.0	2.5	2.2	1.9	2.3	1.4	2.3	1.5	2.2
Illness, injury, bereavement, stress in last 2 years	2.7	3.4	7.0	2.5	0.0	-2.4	-2.2	-1.4	-1.5	-0.9	-2.3	-2.4	-1.3	-1.2	-1.2	-2.0	-1.8	-1.4	-2.4	-1.6	-2.6	-1.4
Knee pain experienced in last month	2.7	4.2	9.8	-3.1	-2.7	-0.6	-1.8	-2.0	-2.4	-2.4	-1.5	-1.7	-2.4	-2.5	-2.0	-1.8	-1.7	-2.2	-1.4	-2.0	-1.0	-2.3
Angina	2.6	3.4	5.6	-1.6	-2.0	-1.3	-2.4	-1.7	-2.2	-1.5	-1.4	-1.9	-2.2	-2.0	-1.9	-2.0	-1.3	-2.3	-1.1	-1.8	-1.5	-2.1
Leg fat-free mass (left)	2.6	14.0	20.2	0.2	-2.8	-2.9	-4.2	-3.9	-4.0	-2.5	-4.5	-4.0	-4.0	-4.0	-3.9	-4.3	-4.0	-4.0	-3.6	-3.8	-4.0	-4.0
Leg predicted mass (left)	2.6	13.9	20.3	0.2	-2.8	-2.9	-4.3	-3.9	-4.1	-2.4	-4.5	-4.0	-4.0	-4.0	-3.8	-4.3	-3.9	-4.0	-3.7	-3.7	-4.0	-4.0
Asthma	2.6	5.2	7.5	1.3	2.5	1.7	1.9	2.4	2.6	2.7	2.3	2.2	2.7	2.3	2.6	2.3	2.1	2.7	1.5	2.5	1.6	2.7
Shortness of breath walking on level ground	2.5	3.0	11.2	-3.3	-3.0	0.6	-0.7	-1.8	-1.6	-2.0	-0.9	-0.9	-1.9	-2.2	-1.9	-1.1	-1.4	-1.7	-0.1	-1.4	-0.4	-1.8
Supplements: Vitamin C	2.5	3.0	5.4	0.4	-1.2	-1.2	-1.9	-1.8	-2.0	-1.5	-1.9	-2.0	-1.7	-1.7	-1.7	-2.1	-1.7	-1.9	-1.4	-1.6	-2.3	-1.7
Medication: Blood pressure	2.4	4.2	6.0	-1.2	-2.3	-1.2	-2.2	-2.1	-2.4	-1.5	-2.0	-2.0	-2.4	-2.4	-2.2	-2.3	-1.9	-2.4	-1.4	-2.1	-1.8	-2.4
Angina (self-reported)	2.4	3.2	5.2	-1.7	-2.0	-1.3	-2.2	-1.7	-2.1	-1.6	-1.3	-1.8	-2.1	-1.9	-1.9	-1.9	-1.2	-2.3	-1.1	-1.7	-1.3	-2.0
Body Mass Index (BMI) (2010)	2.3	3.1	4.7	-1.1	-2.1	-1.3	-1.7	-1.9	-2.0	-1.6	-1.8	-1.6	-2.0	-1.9	-2.2	-1.8	-1.8	-2.0	-1.5	-1.9	-1.2	-1.9
Primary Biliary Cirrhosis	2.3	3.3	5.0	-0.4	-1.9	-1.6	-1.6	-1.9	-2.1	-2.2	-1.7	-1.7	-2.1	-1.7	-2.2	-1.9	-1.7	-2.2	-1.3	-2.0	-1.4	-2.2
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.3	9.6	0.7	-1.8	-2.9	-2.7	-2.6	-2.9	-2.4	-3.0	-3.1	-2.9	-2.4	-2.8	-3.0	-2.7	-2.9	-2.7	-2.9	-2.8	-3.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	3.8	0.7	1.8	1.2	1.6	1.8	1.7	1.3	1.7	1.6	1.9	2.0	1.8	1.6	1.8	1.7	1.7	1.8	1.1	1.8
Whole body fat-free mass	2.3	12.9	19.4	0.4	-2.8	-2.8	-4.1	-3.8	-3.9	-2.1	-4.4	-3.8	-3.9	-3.9	-3.7	-4.1	-3.8	-3.9	-3.4	-3.6	-3.8	-3.9
Number of children fathered	2.2	2.4	4.0	-1.3	-1.5	-1.4	-1.4	-1.6	-1.6	-2.0	-1.4	-1.5	-1.8	-1.5	-1.5	-1.5	-1.4	-1.7	-1.7	-1.9	-1.0	-1.6
Mood swings	2.2	3.9	6.6	-0.2	-1.4	-1.4	-2.2	-2.2	-2.0	-2.0	-2.2	-2.3	-1.9	-2.1	-1.7	-2.2	-2.3	-1.8	-2.3	-1.8	-2.6	-1.9
Whole body water mass	2.2	12.8	19.3	0.3	-2.7	-2.8	-4.1	-3.7	-3.9	-2.1	-4.4	-3.8	-3.9	-3.9	-3.7	-4.1	-3.7	-3.9	-3.4	-3.6	-3.8	-3.9
Age when periods started (menarche)	2.1	5.0	8.4	1.2	2.6	0.5	2.4	2.7	2.3	1.8	2.4	2.2	2.3	2.9	2.7	2.2	2.7	2.2	1.5	1.9	2.2	2.3
Arm predicted mass (right)	2.1	10.8	15.8	0.3	-2.6	-2.6	-3.6	-3.5	-3.5	-2.1	-4.0	-3.5	-3.6	-3.6	-3.4	-3.8	-3.5	-3.6	-3.1	-3.4	-3.4	-3.6
Crohns Disease (2012)	2.0	3.3	5.1	1.4	1.6	1.6	1.6	1.8	2.3	2.0	1.8	1.7	2.2	1.7	1.6	1.9	1.6	2.1	1.7	2.1	1.1	2.1
High blood pressure (mother)	2.0	2.8	4.0	-0.1	-1.0	-1.9	-2.0	-1.5	-1.8	-1.6	-1.6	-2.0	-1.8	-1.4	-1.7	-1.9	-1.4	-1.9	-1.8	-1.8	-1.6	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.1	6.1	0.1	-1.2	-1.9	-2.0	-1.6	-1.7	-2.5	-1.7	-2.3	-1.8	-1.7	-1.2	-1.9	-1.4	-1.7	-2.2	-1.7	-2.0	-1.8
Average weekly fortified wine intake	1.9	2.2	3.2	0.2	-1.1	-1.2	-1.6	-1.6	-1.6	-0.6	-1.8	-1.8	-1.5	-1.6	-1.7	-1.7	-1.8	-1.5	-1.3	-1.3	-1.7	-1.5
Trunk fat-free mass	1.9	11.1	17.1	0.6	-2.5	-2.6	-3.8	-3.4	-3.6	-1.8	-4.1	-3.6	-3.7	-3.6	-3.3	-3.9	-3.4	-3.7	-3.0	-3.4	-3.6	-3.7
Trunk predicted mass	1.9	10.8	16.7	0.5	-2.5	-2.6	-3.8	-3.4	-3.5	-1.8	-4.1	-3.5	-3.7	-3.6	-3.3	-3.9	-3.4	-3.6	-3.0	-3.4	-3.5	-3.7
Eye problems/disorders: Glaucoma	1.9	2.2	4.9	-1.1	0.2	1.8	2.2	0.9	1.8	1.1	1.5	1.9	1.5	1.0	0.8	1.8	0.9	1.7	1.7	1.2	2.0	1.6
Basal metabolic rate	1.9	10.6	15.8	0.2	-2.5	-2.5	-3.7	-3.4	-3.5	-2.0	-4.0	-3.5	-3.6	-3.5	-3.4	-3.8	-3.4	-3.6	-3.1	-3.3	-3.4	-3.6
Arm fat-free mass (right)	1.8	9.4	13.4	-0.3	-2.7	-2.2	-3.4	-3.3	-3.3	-1.8	-3.7	-3.1	-3.5	-3.5	-3.2	-3.5	-3.2	-3.4	-2.8	-3.2	-3.0	-3.4
Ever had bowel cancer screening	1.8	2.1	4.7	0.5	-0.5	-1.3	-2.2	-1.3	-1.6	-0.1	-1.8	-1.6	-1.5	-1.4	-1.1	-1.9	-1.1	-1.7	-0.9	-1.3	-2.1	-1.5
Hearing aid user	1.8	2.1	4.6	-0.5	-0.9	-1.2	-2.1	-1.5	-1.6	-0.7	-1.6	-1.6	-1.4	-1.4	-1.4	-1.6	-1.5	-1.4	-1.4	-1.4	-1.7	-1.5
Commuting to job workplace: Public transport	1.8	2.2	5.2	-0.1	-0.8	-1.8	-1.1	-1.3	-1.4	-2.3	-1.4	-2.0	-1.5	-1.0	-1.4	-1.7	-1.3	-1.5	-1.5	-1.5	-1.6	-1.5
Age at First Birth	1.7	2.4	6.6	2.4	2.6	-0.4	1.3	1.8	1.4	1.6	1.2	1.1	1.7	2.2	1.9	1.1	1.4	1.6	0.5	1.2	0.8	1.6
Loud music exposure frequency	1.7	1.8	6.3	-1.5	-1.7	-1.0	-0.5	-1.3	-1.2	-2.5	-0.8	-1.1	-1.4	-1.2	-1.6	-1.1	-1.1	-1.4	-1.2	-1.8	-0.4	-1.4
Migraine (self-reported)	1.7	2.1	4.2	0.8	1.1	1.6	2.1	1.2	1.8	0.8	1.4	1.6	1.8	1.4	1.2	1.7	0.8	2.0	0.9	1.6	1.2	1.7
Neuroticism (2016)	1.6	2.3	4.0	0.2	-1.5	-0.9	-1.8	-1.8	-1.4	-1.4	-1.8	-1.5	-1.5	-1.9	-1.4	-1.4	-2.0	-1.3	-1.7	-1.5	-1.7	-1.4
Sensitivity / hurt feelings	1.6	2.7	5.4	0.3	-0.9	-1.9	-1.8	-1.8	-1.6	-1.9	-1.8	-1.6	-1.4	-1.4	-1.4	-1.6	-1.9	-1.4	-2.3	-1.7	-1.9	-1.5
Supplements: Glucosamine	1.6	2.1	5.4	-0.0	-0.5	-2.3	-1.5	-1.2	-1.4	-0.9	-1.4	-1.9	-1.5	-0.9	-1.2	-1.8	-1.1	-1.6	-1.3	-1.8	-1.8	-1.5
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.5	3.0	-0.5	-1.4	-1.5	-1.7	-1.7	-1.6	-1.5	-1.7	-1.7	-1.7	-1.6	-1.5	-1.7	-1.6	-1.6	-1.5	-1.7	-1.6	-1.7
Medication: Simvastatin	1.6	2.3	3.9	-1.6	-1.1	-1.8	-1.3	-1.3	-1.7	-2.0	-1.1	-1.4	-1.7	-1.1	-1.6	-1.6	-1.0	-1.8	-1.4	-1.8	-0.9	-1.8
Fluid intelligence score	1.6	3.4	9.7	2.8	3.1	-0.3	1.3	2.0	1.8	1.8	1.2	1.3	2.2	2.4	2.2	1.5	1.7	2.0	0.3	1.5	0.9	2.1
Wheeze or whistling in the chest in last year	1.6	2.9	5.9	1.0	2.1	1.8	1.0	1.8	1.6	1.9	1.4	1.5	1.9	1.5	2.4	1.5	1.8	1.9	1.5	2.1	0.6	1.9
Vascular/heart problems diagnosed by doctor	1.6	4.4	6.9	1.9	2.3	1.5	2.4	2.0	2.5	1.5	1.8	2.1	2.5	2.2	2.4	2.2	1.6	2.6	1.1	2.1	1.5	2.6
Respiratory disease	1.5	3.2	5.5	1.3	2.3	0.8	1.2	1.9	1.9	2.3	1.6	1.6	2.2	2.0	2.3	1.8	1.6	2.2	0.6	2.0	1.1	2.1
Hand grip strength (left)	1.5	3.9	6.7	-0.4	-2.3	-0.8	-2.2	-2.2	-1.9	-1.5	-2.1	-2.2	-2.2	-2.6	-2.1	-2.1	-2.2	-2.1	-1.5	-1.9	-1.8	-2.1
Pain all over the body in last month	1.5	1.6	2.9	-0.7	0.7	0.7	1.4	1.3	1.3	1.1	1.7	1.4	1.2	1.5	1.2	1.3	1.7	1.1	1.4	1.2	1.6	1.2
Illnesses of siblings	1.5	2.1	3.1	0.4	1.4	0.8	1.5	1.7	1.4	1.6	1.4	1.6	1.4	1.7	1.5	1.4	1.8	1.3	1.8	1.4	1.6	1.5
Forced vital capacity (FVC), Best measure	1.5	5.4	8.9	0.9	-1.1	-3.0	-2.5	-2.0	-2.6	-1.7	-2.6	-2.7	-2.5	-1.8	-2.4	-2.7	-2.1	-2.6	-2.1	-2.4	-2.5	-2.7
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	5.4	2.3	2.1	0.5	0.7	1.2	1.6	1.4	0.7	0.7	1.6	1.3	1.8	1.0	0.9	1.6	0.3	1.4	-0.1	1.5
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	5.1	-2.2	-2.2	-0.7	-0.8	-1.6	-1.7	-2.2	-0.9	-1.3	-1.8	-1.6	-2.0	-1.4	-1.2	-1.9	-0.5	-1.6	-0.6	-1.7
Illnesses of father: None of the above (group 1)	1.5	1.8	4.2	-1.8	-0.5	1.9	2.0	0.7	1.2	1.0	1.4	2.0	0.9	0.7	0.4	1.5	0.7	1.1	1.7	1.1	2.0	1.0
Severe depression (siblings)	1.4	1.6	4.6	0.8	0.1	-1.3	-1.7	-1.1	-1.1	-1.2	-1.6	-1.6	-0.8	-1.0	-0.7	-1.4	-1.4	-0.9	-1.7	-0.9	-2.1	-0.8
Qualifications: A levels/AS levels or equivalent	1.4	3.0	5.4	1.8	-0.7	-2.1	-2.1	-1.7	-1.4	-0.8	-2.1	-2.3	-1.4	-1.4	-1.5	-2.0	-1.7	-1.5	-1.9	-1.8	-2.3	-1.5
Emphysema/chronic bronchitis	1.4	1.6	2.3	-1.2	-1.2	-0.7	-1.2	-1.3	-1.5	-1.1	-1.3	-1.3	-1.4	-1.3	-1.3	-1.4	-1.2	-1.4	-0.7	-1.1	-1.5	-1.4
Medication for pain relief, constipation, heartburn	1.4	2.4	4.9	2.2	1.8	1.4	1.2	1.4	1.8	1.5	1.0	1.2	1.8	1.4	1.9	1.4	1.3	1.8	1.3	1.8	0.5	1.8
Alcohol intake frequency.	1.4	3.2	5.1	0.4	1.6	1.0	2.3	1.9	2.0	1.0	2.2	2.0	2.0	2.1	1.8	2.1	1.9	2.0	1.3	1.6	1.9	1.9
Number of full sisters	1.4	1.7	9.9	-3.1	-2.6	0.1	-0.1	-1.0	-1.1	-1.5	0.0	-0.1	-1.4	-1.3	-1.4	-0.4	-0.4	-1.3	-0.1	-1.3	0.9	-1.3
Commuting to job workplace: Cycle	1.4	1.6	4.0	1.7	0.5	-2.0	-2.0	-0.8	-1.1	-0.2	-1.6	-1.6	-0.8	-0.6	-0.5	-1.4	-1.1	-0.9	-1.6	-1.1	-1.9	-0.8
Depression (Nagel 2018)	1.3	2.0	8.2	-2.9	-2.8	0.4	-0.4	-1.6	-0.9	-1.0	-0.7	-0.5	-1.5	-1.9	-1.8	-0.7	-1.3	-1.1	-0.2	-1.1	0.4	-1.4
Fed-up feelings	1.3	2.3	5.5	-1.8	-2.3	-0.4	-1.4	-1.7	-1.7	-1.2	-1.2	-1.3	-1.7	-2.0	-1.7	-1.3	-1.6	-1.5	-1.1	-1.4	-1.0	-1.6
Qualifications: None of the above	1.3	2.9	20.7	-4.5	-1.8	2.6	1.7	0.4	0.4	-0.3	1.8	1.8	0.1	-0.0	-0.1	1.2	1.0	0.1	2.5	0.8	2.3	0.3
Medication: Ibuprofen	1.3	1.6	2.6	-1.0	-0.9	-1.6	-1.0	-1.2	-1.2	-1.6	-0.9	-1.4	-1.3	-1.1	-1.1	-1.3	-1.1	-1.2	-1.6	-1.6	-1.0	-1.3
Arm fat-free mass (left)	1.3	6.5	10.0	-0.0	-2.2	-1.8	-2.8	-2.8	-2.7	-1.2	-3.2	-2.6	-2.9	-2.9	-2.8	-2.9	-2.7	-2.8	-2.3	-2.6	-2.5	-2.9
Diastolic blood pressure, automated reading	1.3	4.2	7.9	-1.3	-2.8	-0.5	-2.0	-2.4	-2.0	-1.7	-2.2	-1.8	-2.1	-2.7	-2.5	-1.9	-2.6	-2.0	-1.6	-1.8	-1.6	-2.1
Blood Red Count	1.2	11.6	17.6	0.8	2.3	3.2	4.2	3.4	3.8	2.9	3.6	3.9	3.6	3.3	2.9	3.9	3.3	3.8	3.4	3.6	3.9	3.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.4	2.2	-1.2	-1.5	-0.7	-1.1	-1.2	-1.4	-0.8	-1.2	-0.9	-1.4	-1.3	-1.4	-1.1	-1.1	-1.5	-0.6	-1.3	-0.7	-1.4
Medication: Cholesterol lowering	1.2	1.8	4.5	-0.6	-0.5	-2.1	-1.6	-1.0	-1.5	-1.2	-1.0	-1.6	-1.4	-0.8	-1.2	-1.5	-0.9	-1.6	-1.7	-1.5	-1.2	-1.4
Pulse wave reflection index	1.2	1.5	2.4	-0.1	-1.2	-1.4	-1.2	-1.5	-1.1	-1.0	-1.3	-1.0	-1.2	-1.2	-1.5	-1.2	-1.5	-1.3	-1.3	-1.5	-1.0	-1.3
Blood clot in the leg (DVT)	1.2	1.5	2.7	0.2	0.6	1.4	1.5	1.4	1.0	0.8	1.6	1.6	1.0	1.1	1.1	1.3	1.6	0.9	1.4	1.2	1.6	1.0
Headache pain in last month	1.2	2.0	2.9	0.3	1.3	1.5	1.2	1.5	1.6	1.2	1.4	1.5	1.7	1.4	1.5	1.6	1.3	1.7	1.0	1.7	1.0	1.7
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	3.4	0.3	0.7	1.8	1.7	1.1	1.7	0.9	1.2	1.6	1.6	1.0	1.2	1.7	0.9	1.8	1.3	1.6	1.4	1.6
Age at last live birth	1.2	1.8	3.3	0.4	-0.7	-1.7	-1.8	-1.1	-1.6	-0.4	-1.5	-1.6	-1.2	-1.0	-1.2	-1.5	-1.3	-1.4	-1.5	-1.3	-1.5	-1.4
HDL Cholesterol	1.1	1.8	4.6	2.2	1.9	0.6	1.1	1.4	1.6	1.4	1.1	0.9	1.5	1.5	1.4	1.1	1.2	1.4	0.9	1.3	0.6	1.5
Lupus	1.1	1.6	4.2	-1.5	-2.1	-0.6	-0.8	-1.6	-1.1	-1.2	-0.9	-1.0	-1.3	-1.6	-1.7	-1.0	-1.4	-1.3	-1.0	-1.4	-0.5	-1.2
Waist Hip Ratio (WHR)	1.1	4.9	7.7	0.1	1.7	2.2	1.8	2.2	2.3	2.1	2.4	2.3	2.4	2.2	2.2	2.5	2.3	2.4	2.5	2.8	2.0	2.4
Neuroticism	1.1	2.7	4.4	-1.6	-1.9	-0.4	-1.9	-1.8	-1.9	-1.0	-1.7	-1.6	-1.8	-2.1	-1.5	-1.7	-1.7	-1.6	-1.2	-1.4	-1.6	-1.8
Ever had hysterectomy (womb removed)	1.1	1.3	2.9	-1.3	-1.6	-0.7	-0.4	-1.4	-1.0	-1.7	-0.7	-0.7	-1.2	-1.1	-1.6	-0.9	-1.1	-1.3	-0.5	-1.4	-0.4	-1.1
Forced expiratory volume in 1-second (FEV1)	1.1	3.7	5.8	1.6	-0.9	-2.1	-2.3	-1.7	-2.0	-1.2	-2.3	-2.4	-1.9	-1.6	-1.8	-2.3	-1.8	-2.0	-1.9	-1.9	-2.4	-2.0
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	4.1	1.7	0.1	-1.7	-1.4	-1.1	-1.1	-0.8	-1.7	-1.8	-0.9	-0.9	-0.9	-1.5	-1.4	-0.8	-2.0	-1.2	-1.9	-1.0
Arm predicted mass (left)	1.1	5.5	8.6	0.1	-2.0	-1.7	-2.5	-2.5	-2.5	-1.1	-2.9	-2.4	-2.7	-2.7	-2.5	-2.7	-2.5	-2.6	-2.1	-2.4	-2.4	-2.7
Alzheimer’s Disease (including proxy)	1.0	1.5	2.6	0.9	1.4	0.8	1.0	1.3	1.5	1.6	1.2	0.9	1.4	1.4	1.3	1.2	1.2	1.4	0.9	1.3	0.7	1.4
Relative age of first facial hair	1.0	2.0	3.7	1.6	1.9	0.5	1.3	1.3	1.8	0.7	1.3	1.1	1.9	1.6	1.9	1.5	1.0	1.9	0.3	1.4	0.7	1.8
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.2	0.1	-1.0	-0.7	-1.2	-1.1	-1.2	-0.9	-1.3	-1.4	-1.2	-1.3	-1.1	-1.4	-1.1	-1.2	-1.1	-0.9	-1.5	-1.2
Hand grip strength (right)	1.0	2.6	3.8	0.1	-1.8	-1.0	-1.7	-1.8	-1.5	-1.5	-1.7	-1.7	-1.8	-2.0	-1.7	-1.7	-1.8	-1.8	-1.4	-1.6	-1.4	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	4.4	-0.3	1.1	1.2	2.1	1.4	1.8	1.2	1.8	1.7	1.6	1.5	1.4	1.7	1.5	1.7	1.6	1.4	1.6	1.5
Neuroticism score	1.0	2.1	3.3	-1.7	-1.8	-0.9	-1.5	-1.6	-1.6	-1.3	-1.3	-1.4	-1.5	-1.7	-1.4	-1.4	-1.6	-1.4	-1.4	-1.4	-1.2	-1.5
Medication: Lansoprazole	1.0	1.1	12.1	-3.5	-1.7	1.4	0.1	-0.4	-0.6	-0.4	0.2	0.6	-0.6	-0.7	-0.8	0.0	0.1	-0.6	0.9	-0.1	0.8	-0.5
Neck or shoulder pain in last month	1.0	1.5	2.8	0.8	1.4	0.6	0.4	1.5	1.2	1.7	1.1	0.9	1.2	1.3	1.6	1.1	1.6	1.2	1.0	1.3	0.7	1.4
Had major operations	1.0	1.1	1.7	0.7	-0.9	-1.2	-1.2	-1.1	-0.9	-0.9	-1.0	-1.2	-1.1	-1.0	-1.0	-1.1	-1.0	-1.1	-1.3	-1.1	-1.2	-1.1
Hypertension (Self-reported)	1.0	2.8	4.4	-2.1	-2.1	-0.8	-1.7	-1.6	-2.1	-1.1	-1.4	-1.5	-2.0	-1.9	-1.9	-1.7	-1.2	-2.0	-0.6	-1.7	-1.0	-2.1
Miserableness	1.0	1.8	3.2	-1.8	-1.6	-0.2	-1.3	-1.5	-1.4	-1.4	-1.3	-1.2	-1.4	-1.8	-1.2	-1.3	-1.5	-1.3	-1.0	-1.0	-1.3	-1.3
Financial situation satisfaction	1.0	1.3	2.7	0.2	-0.3	-1.2	-1.5	-1.1	-1.0	-1.3	-1.2	-1.4	-1.1	-1.1	-0.5	-1.2	-1.1	-1.0	-1.6	-1.1	-1.4	-1.0
Bipolar Disorder (2011)	0.9	0.9	1.9	-0.9	0.2	0.5	0.7	1.0	1.1	1.4	1.3	0.9	0.8	0.8	0.7	1.1	1.2	0.9	1.0	0.6	1.4	0.7
Rheumatoid Arthritis	0.9	1.2	5.0	-2.2	-2.2	0.3	-0.0	-0.9	-0.9	-1.2	-0.2	-0.3	-1.1	-1.1	-1.6	-0.5	-0.5	-1.1	0.4	-0.9	0.5	-1.1
BMI	0.9	5.3	8.6	-0.9	-2.2	-1.8	-2.4	-2.6	-2.4	-2.2	-2.3	-2.1	-2.4	-2.6	-2.5	-2.2	-2.6	-2.3	-2.9	-2.5	-1.8	-2.3
High blood pressure	0.9	2.5	4.8	-2.2	-2.1	-0.6	-1.6	-1.5	-1.9	-1.0	-1.2	-1.4	-1.9	-1.8	-1.8	-1.5	-1.1	-1.9	-0.4	-1.5	-0.9	-2.0
Forced vital capacity (FVC)	0.9	3.4	5.8	1.5	-0.6	-2.4	-2.2	-1.5	-1.9	-1.1	-2.2	-2.3	-1.8	-1.3	-1.7	-2.3	-1.5	-2.0	-1.7	-1.8	-2.4	-2.0
Leg fat percentage (right)	0.9	3.3	7.2	-1.6	0.2	2.3	2.3	1.6	1.6	0.7	2.4	2.2	1.6	1.4	1.3	2.2	1.7	1.7	1.7	1.8	2.7	1.7
Average weekly red wine intake	0.9	1.4	3.9	2.0	0.1	-1.8	-1.5	-0.9	-0.7	-0.2	-1.3	-1.6	-0.9	-0.7	-0.5	-1.3	-0.8	-0.9	-1.1	-1.1	-1.7	-0.9
Medication: Gliclazide	0.9	1.0	1.9	-1.2	-0.6	-1.0	-1.4	-0.8	-1.2	-0.9	-0.9	-1.2	-1.0	-0.9	-0.9	-1.1	-0.8	-1.2	-1.0	-0.9	-1.1	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	3.4	-0.1	-1.2	-0.8	-1.9	-1.4	-1.6	-1.0	-1.6	-1.5	-1.7	-1.6	-1.2	-1.7	-1.2	-1.7	-0.9	-1.3	-1.6	-1.6
Average weekly beer plus cider intake	0.9	1.3	4.1	-2.0	-2.0	0.5	-1.1	-1.0	-1.4	-1.3	-0.4	-0.8	-1.4	-1.6	-1.0	-0.8	-0.7	-1.2	0.1	-0.7	-0.3	-1.1
Reaction Time	0.8	1.5	5.9	-2.4	-1.0	2.3	1.3	0.6	0.6	0.4	1.2	1.4	0.5	0.2	0.0	1.1	0.9	0.5	2.1	1.1	1.7	0.5
LDL Cholesterol	0.8	1.3	1.8	0.7	-0.9	-0.8	-1.4	-1.2	-1.2	-1.1	-1.3	-1.3	-1.3	-1.3	-0.9	-1.2	-1.1	-1.2	-1.1	-1.2	-1.2	-1.2
Trunk fat percentage	0.8	3.0	4.2	0.1	1.6	1.4	2.0	1.9	1.6	1.2	2.0	2.0	2.0	2.0	1.6	2.0	1.8	1.8	1.1	1.9	2.0	1.9
Taking other prescription medications	0.8	1.2	6.9	-2.6	-0.4	1.1	0.8	0.8	0.5	0.8	1.4	1.3	0.5	0.7	0.3	0.9	1.2	0.3	1.3	0.6	1.7	0.5
Chronic bronchitis/emphysema (father)	0.8	0.9	1.5	-0.1	0.8	0.7	0.9	1.1	1.0	0.9	1.2	1.0	1.0	1.0	1.2	1.1	1.2	1.0	0.8	1.0	0.9	1.0
Number of incorrect matches in round	0.8	1.2	2.1	-0.6	-1.2	-1.0	-1.3	-1.0	-1.4	-0.6	-1.1	-1.1	-1.4	-1.0	-1.2	-1.3	-0.7	-1.4	-0.4	-1.3	-0.9	-1.4
Financial difficulties in last 2 years	0.8	1.1	11.7	-3.4	-1.3	0.1	0.7	-0.4	-0.2	-1.8	0.6	0.4	-0.4	-0.3	-0.5	0.3	-0.1	-0.3	-0.0	-0.7	1.2	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	2.2	0.2	-0.4	-1.3	-1.5	-0.5	-1.3	-0.8	-0.9	-1.4	-1.3	-0.7	-0.4	-1.4	-0.1	-1.3	-0.5	-1.0	-1.4	-1.3
Overall health rating	0.8	1.6	4.2	-2.0	-0.0	2.1	1.0	1.0	0.8	1.3	1.3	1.5	0.9	0.5	1.0	1.4	1.1	1.1	1.5	1.4	1.6	1.0
Osteoarthritis (self-reported)	0.8	1.1	2.4	0.3	1.6	0.1	0.8	1.3	1.1	0.8	1.1	0.8	1.1	1.4	1.3	0.9	1.5	0.9	0.7	0.9	0.7	1.0
Medication: Blood pressure	0.8	1.6	9.2	-3.0	-2.2	-0.1	-0.1	-1.2	-1.0	-1.5	-0.3	-0.5	-1.3	-1.3	-1.4	-0.6	-0.8	-1.1	-0.2	-1.2	0.3	-1.2
Ever depressed for a whole week	0.8	1.0	1.9	0.1	-0.7	-0.5	-0.9	-1.3	-0.6	-1.3	-1.1	-1.2	-0.8	-1.2	-0.9	-0.9	-1.4	-0.6	-1.1	-0.8	-1.3	-0.8
Pain experienced in last month	0.8	1.3	2.5	0.5	-0.9	-1.4	-0.4	-1.3	-1.1	-1.2	-1.2	-0.9	-1.1	-0.9	-1.5	-1.0	-1.6	-1.1	-1.3	-1.4	-0.8	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.0	0.2	0.4	1.2	1.3	1.1	0.7	0.5	1.3	1.3	0.7	0.9	0.9	1.0	1.4	0.6	1.2	0.9	1.4	0.7
Crohns Disease (2017)	0.7	1.6	2.7	-0.4	0.2	1.5	1.4	1.1	1.3	1.1	1.6	1.5	1.4	1.1	0.7	1.5	1.0	1.3	1.6	1.4	1.4	1.4
Coronary Artery Disease (CAD)	0.7	0.8	3.8	1.3	1.9	-0.9	0.3	0.9	0.7	1.3	0.4	0.4	1.1	1.2	1.0	0.2	0.6	1.0	-0.3	0.7	-0.1	0.8
Mean Putamen Volume	0.7	0.8	5.1	2.2	1.1	0.5	0.8	0.6	1.0	0.6	0.2	0.4	1.0	0.5	0.9	0.6	0.2	1.1	-0.0	0.8	-0.0	0.9
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.7	-0.2	-0.8	-1.0	-0.6	-0.9	-1.1	-1.0	-0.7	-0.8	-1.0	-0.7	-1.3	-0.9	-0.8	-1.1	-0.4	-1.1	-0.6	-1.0
Sitting height	0.7	5.0	9.7	2.1	-0.4	-2.6	-2.8	-1.8	-2.3	-0.3	-3.1	-2.6	-2.2	-1.8	-1.7	-2.8	-1.9	-2.4	-1.9	-2.1	-3.0	-2.4
Hearing difficulty/problems with background noise	0.7	1.2	3.6	1.7	1.9	0.5	-0.1	1.2	0.8	1.9	0.5	0.2	0.8	1.0	1.4	0.4	1.3	0.8	1.1	1.2	-0.3	0.7
Diabetes (self-reported)	0.7	1.1	4.0	-2.0	-0.8	-1.2	-0.8	-0.8	-1.5	-1.2	-0.7	-0.4	-1.1	-0.5	-1.2	-0.9	-0.6	-1.5	-0.7	-1.2	-0.1	-1.2
Depression (self-reported)	0.7	0.9	1.6	-1.3	-0.9	-0.7	-1.0	-0.9	-1.1	-0.6	-0.8	-1.1	-1.1	-1.0	-0.8	-1.0	-0.8	-0.9	-1.0	-1.0	-0.6	-1.1
Length of working week for main job	0.7	0.8	2.2	1.5	1.3	0.5	0.6	1.0	0.8	0.8	0.7	0.5	1.2	1.0	1.0	0.7	0.8	0.9	0.4	1.1	-0.1	1.1
Glaucoma (self-reported)	0.7	0.8	1.9	-0.1	0.5	1.4	1.1	0.5	1.2	0.9	0.6	1.0	1.1	0.5	0.6	1.0	0.4	1.2	1.0	1.0	0.6	1.1
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.4	-1.9	-1.1	-0.8	-0.2	-1.0	-0.7	-0.9	-0.6	-0.4	-0.8	-0.7	-1.1	-0.5	-0.9	-0.7	-0.7	-1.1	-0.1	-0.9
Body fat percentage	0.7	2.8	4.5	-0.4	1.1	1.5	2.0	1.8	1.5	0.9	2.1	2.0	1.8	1.8	1.4	2.0	1.7	1.7	1.1	1.8	2.1	1.8
Medication: Bendroflumethiazide	0.7	1.1	1.6	-0.6	-1.1	-1.0	-0.9	-1.1	-1.1	-0.9	-1.0	-1.1	-1.2	-1.2	-1.0	-1.0	-1.1	-1.0	-1.1	-1.2	-0.7	-1.2
Medication: Lisinopril	0.7	0.9	2.2	-1.2	0.3	0.7	1.3	0.9	0.8	0.7	1.2	1.1	0.6	1.0	0.3	0.9	1.2	0.5	1.5	0.7	1.4	0.7
Leg fat percentage (left)	0.7	2.7	6.5	-1.6	0.1	2.1	2.2	1.4	1.4	0.5	2.2	2.0	1.5	1.2	1.1	2.0	1.5	1.6	1.4	1.5	2.6	1.5
Irritability	0.7	1.1	2.9	-1.3	-1.1	-0.8	-0.6	-1.0	-1.2	-1.7	-0.9	-1.1	-1.1	-1.1	-0.9	-1.0	-1.1	-1.0	-1.0	-1.1	-0.8	-1.1
Alzheimer’s Disease (in mother)	0.6	0.7	1.2	-0.0	0.5	1.1	0.9	0.8	1.0	1.0	0.9	0.8	1.0	0.7	0.9	1.0	0.7	1.0	0.8	1.1	0.7	1.0
Fasting Glucose	0.6	0.7	2.4	-0.0	0.5	1.1	0.7	0.8	0.6	0.7	1.0	0.8	0.9	0.8	0.7	0.8	0.9	0.7	1.5	1.1	0.5	0.8
Ulcerative Colitis	0.6	0.9	2.1	0.5	1.0	-0.2	0.9	1.0	0.9	1.2	0.9	1.2	1.1	1.4	0.5	1.0	1.0	0.7	1.1	0.8	0.8	0.9
Heel T-Score	0.6	4.8	9.1	1.3	2.6	-0.2	2.2	2.6	2.4	2.2	2.6	2.0	2.4	3.0	2.3	2.2	2.7	2.1	1.4	1.7	2.2	2.2
Current tobacco smoking	0.6	0.9	1.9	-1.1	-1.4	-0.1	-1.0	-1.1	-0.9	-0.9	-0.8	-0.7	-1.1	-1.3	-0.8	-0.9	-0.9	-1.0	-0.6	-1.0	-0.8	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	5.6	-2.4	-0.8	1.2	0.9	0.2	0.6	-0.0	0.9	1.0	0.3	-0.0	0.1	0.9	0.4	0.5	1.0	0.4	1.5	0.4
Body mass index (BMI)	0.6	2.4	3.7	-1.2	-1.9	-0.7	-1.4	-1.7	-1.7	-1.7	-1.4	-1.3	-1.7	-1.9	-1.8	-1.4	-1.7	-1.6	-1.7	-1.7	-0.8	-1.7
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.5	-1.1	-0.7	-0.7	-0.7	-0.9	-0.9	-1.2	-0.7	-0.9	-1.0	-0.9	-0.8	-1.0	-0.8	-0.9	-1.0	-1.0	-0.6	-0.9
Mean time to correctly identify matches	0.6	1.2	4.3	-1.7	-0.4	1.7	1.3	0.7	0.6	0.7	1.1	1.3	0.6	0.5	0.2	1.0	1.1	0.5	2.1	1.0	1.5	0.5
Medication for cholesterol	0.6	0.9	3.0	1.7	0.9	0.7	0.6	0.9	1.1	1.7	0.5	0.8	1.1	0.8	1.0	0.7	0.6	1.1	0.7	1.0	0.3	1.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.6	0.2	0.7	0.5	0.7	0.9	0.8	1.3	0.8	0.9	0.9	1.0	0.8	0.7	0.9	0.8	0.7	0.8	0.7	0.9
Intelligence (Savage-Jansen 2018)	0.5	1.7	3.0	1.1	1.3	0.5	1.7	1.3	1.5	1.1	1.1	1.4	1.6	1.6	1.0	1.4	0.9	1.5	0.7	1.2	1.4	1.5
Schizophrenia (2018)	0.5	1.0	7.5	1.0	1.0	-0.2	-0.4	1.2	0.3	2.7	0.6	0.8	0.5	1.3	0.8	0.3	1.4	0.2	1.2	0.6	0.6	0.3
Schizophrenia (2014)	0.5	1.0	5.6	1.9	1.5	-1.0	-0.9	1.0	0.1	2.4	0.2	0.3	0.4	1.4	0.7	-0.1	1.2	-0.0	0.5	0.3	-0.1	0.2
Frequency of depressed mood in last 2 weeks	0.5	0.6	4.1	-2.0	-1.6	0.2	-0.1	-0.8	-0.6	-0.3	-0.3	-0.1	-0.8	-1.0	-0.9	-0.2	-0.6	-0.5	-0.1	-0.7	0.6	-0.7
Pack years adult smoking proportion	0.5	0.8	1.8	0.3	-0.8	-0.2	-0.9	-1.1	-0.7	-1.3	-1.1	-0.9	-0.8	-1.3	-0.7	-0.8	-1.2	-0.6	-1.1	-0.8	-0.9	-0.8
Serious illness, injury or assault to yourself	0.5	0.6	3.5	-1.9	-1.2	0.1	-0.2	-0.7	-0.9	-0.8	-0.3	-0.2	-0.8	-0.7	-1.0	-0.5	-0.6	-0.9	-0.1	-0.5	-0.0	-0.9
Stomach or abdominal pain in last month	0.5	0.6	2.6	-1.3	-0.1	1.2	0.1	0.6	0.4	1.3	0.7	0.5	0.3	0.1	0.4	0.4	0.9	0.3	1.6	0.8	0.5	0.3
Weight	0.5	2.3	3.4	0.0	-1.3	-1.0	-1.7	-1.6	-1.8	-0.8	-1.8	-1.5	-1.7	-1.7	-1.7	-1.7	-1.6	-1.8	-1.5	-1.5	-1.4	-1.7
Happiness	0.5	0.5	2.5	1.1	1.6	0.2	-0.4	0.7	0.6	1.2	0.1	0.2	0.7	0.6	1.2	0.3	0.5	0.7	-0.0	0.8	-0.3	0.7
Noisy workplace	0.5	0.6	2.0	-1.2	-0.4	1.4	0.7	0.7	0.6	0.3	0.9	0.8	0.4	0.2	0.7	0.8	0.9	0.5	1.1	0.7	1.1	0.5
Birth weight of first child	0.5	0.9	4.5	2.1	0.7	-0.6	-1.2	-0.5	-0.4	0.6	-1.2	-1.0	-0.2	-0.4	-0.4	-1.0	-0.9	-0.3	-1.0	-0.2	-1.8	-0.3
Ever highly irritable/argumentative for 2 days	0.5	0.5	1.6	0.2	-0.1	-0.9	-1.2	-0.6	-0.6	-0.6	-0.9	-1.0	-0.6	-0.6	-0.2	-0.8	-0.6	-0.6	-0.8	-0.6	-1.3	-0.6
Medication: Paracetamol	0.5	0.9	6.0	-2.5	-1.9	0.3	0.1	-0.8	-0.7	-1.1	-0.1	-0.0	-0.8	-0.9	-1.2	-0.2	-0.6	-0.7	-0.0	-0.7	0.5	-0.8
Worry too long after embarrassment	0.5	0.8	1.4	-1.2	-1.2	-0.6	-0.7	-1.1	-0.9	-0.5	-0.7	-0.7	-0.8	-0.9	-1.2	-0.8	-1.0	-0.9	-0.6	-0.9	-0.6	-0.9
Heart disease (mother)	0.5	0.6	4.8	-2.2	-1.6	0.7	0.1	-0.7	-0.4	-0.5	0.2	0.2	-0.5	-0.8	-0.9	0.1	-0.4	-0.5	0.6	-0.4	0.5	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.4	-0.2	0.2	1.0	0.7	0.8	0.8	0.5	1.0	1.0	0.7	0.5	0.8	1.0	0.9	0.7	1.2	0.8	1.0	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.9	1.7	1.5	0.3	0.2	0.7	0.6	0.7	0.0	0.3	0.7	0.6	1.4	0.3	0.4	0.9	-0.0	0.7	-0.5	0.7
Mother’s age at death	0.5	0.6	2.3	0.3	0.1	-1.5	-0.4	-0.6	-0.8	-0.9	-0.7	-0.8	-0.9	-0.3	-0.9	-0.9	-0.4	-1.0	-0.6	-1.0	-0.5	-1.1
Pack years of smoking	0.5	0.7	1.5	0.0	-0.9	0.1	-0.8	-1.1	-0.6	-1.0	-1.0	-0.8	-0.7	-1.2	-0.7	-0.7	-1.1	-0.5	-0.9	-0.6	-0.9	-0.6
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.0	1.4	1.2	0.0	1.0	0.9	0.9	1.1	0.5	0.9	1.1	1.1	0.8	0.9	0.6	1.1	0.2	0.7	0.7	1.1
Breast Cancer	0.4	0.8	4.5	2.1	2.0	-0.1	-1.0	0.6	0.3	1.2	-0.3	-0.0	0.7	0.5	1.2	-0.0	0.3	0.4	-0.2	0.7	-1.1	0.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	-0.9	-0.1	0.9	0.5	0.6	0.7	0.6	0.8	1.0	0.4	0.6	0.3	1.2	0.7	0.2	1.0	0.4	0.8	0.5
Blood Platelet Count	0.4	4.1	6.6	1.7	2.3	1.8	1.9	1.9	2.3	1.9	1.6	2.2	2.5	1.9	2.4	2.2	1.4	2.6	1.3	2.3	1.4	2.5
Medication: Co-codamol	0.4	0.4	3.8	-1.9	-0.2	0.7	0.7	0.5	0.0	-0.0	0.7	0.5	0.1	0.5	-0.0	0.3	0.5	-0.1	0.8	0.4	0.8	0.2
Medication: Atenolol	0.4	0.4	5.5	-2.4	-0.9	0.6	0.3	-0.3	-0.4	-0.3	0.2	0.5	-0.3	-0.4	-0.5	-0.0	-0.2	-0.4	0.3	-0.2	0.5	-0.2
Nervous feelings	0.4	0.8	1.3	-0.5	0.4	1.2	0.9	0.9	0.8	0.7	0.9	0.9	0.9	0.7	0.9	1.0	0.7	1.1	0.8	1.0	0.9	0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.8	1.0	0.2	-0.8	-0.8	-0.7	-0.3	-0.6	-0.9	-1.0	-0.4	-0.6	-0.3	-0.8	-0.7	-0.4	-0.9	-0.6	-1.3	-0.4
Arm fat percentage (right)	0.4	1.4	2.6	-0.4	0.8	1.1	1.5	1.2	1.1	0.4	1.5	1.5	1.4	1.3	1.0	1.5	1.2	1.3	0.6	1.2	1.6	1.4
Breastfed as a baby	0.4	0.5	1.0	-0.4	-0.8	-0.3	-0.5	-0.9	-0.5	-0.9	-0.6	-0.8	-0.7	-1.0	-0.6	-0.7	-0.7	-0.6	-0.4	-0.6	-0.7	-0.7
Comparative body size at age 10	0.4	1.0	2.2	-0.1	-1.3	0.0	-1.0	-1.3	-0.7	-0.8	-1.2	-1.0	-0.9	-1.5	-1.1	-0.9	-1.4	-0.8	-0.9	-0.9	-0.9	-0.7
Age at first live birth	0.4	0.8	1.8	0.2	-0.4	-1.3	-1.0	-0.8	-1.0	0.2	-1.0	-1.0	-0.7	-0.5	-1.1	-1.0	-1.1	-0.9	-0.9	-0.9	-0.9	-0.8
Comparative height size at age 10	0.4	2.0	4.7	1.0	-0.5	-0.4	-2.2	-1.0	-1.6	0.9	-2.0	-1.5	-1.6	-1.4	-1.3	-2.0	-0.9	-1.8	-0.0	-0.8	-2.0	-1.5
Leg pain on walking	0.4	0.5	2.0	1.3	0.1	-0.3	-1.4	-0.3	-0.7	0.2	-0.7	-0.9	-0.6	-0.5	-0.0	-1.0	-0.1	-0.7	-0.3	-0.2	-1.3	-0.5
Qualifications: nursing, teaching	0.4	0.7	6.2	2.5	1.4	-0.2	-0.4	0.6	0.5	1.0	-0.2	-0.3	0.6	0.7	0.7	0.0	0.5	0.5	0.0	0.7	-0.6	0.5
Back pain experienced in last month	0.4	0.6	2.3	-0.5	0.0	1.5	0.3	0.7	0.6	0.7	0.8	0.6	0.5	0.3	1.0	0.6	1.0	0.5	1.3	1.0	0.5	0.7
Smoking status: Current	0.4	0.6	1.3	-0.8	-1.1	0.1	-0.9	-0.8	-0.8	-0.7	-0.7	-0.6	-1.0	-1.2	-0.5	-0.8	-0.6	-0.8	-0.4	-0.7	-0.7	-0.8
Number of self-reported non-cancer illnesses	0.4	0.8	2.5	-1.4	0.0	1.0	0.2	0.9	0.4	1.6	1.2	0.8	0.5	0.6	0.6	0.6	1.2	0.4	1.3	0.8	0.8	0.5
Pain type(s) experienced in last month: Hip pain	0.4	0.5	4.2	-2.1	-1.1	0.3	0.3	-0.3	-0.0	-1.3	0.5	-0.1	-0.4	-0.4	-0.2	0.2	0.1	-0.1	-0.0	-0.3	0.6	-0.3
Medication: Paracetamol	0.4	0.7	2.6	-1.6	-1.5	-0.4	-0.1	-0.7	-0.8	-1.0	-0.2	-0.4	-0.9	-0.7	-1.1	-0.4	-0.5	-0.8	-0.3	-0.9	0.3	-0.9
Number of operations (self-reported)	0.4	0.5	1.3	0.9	-0.5	-1.2	-0.6	-0.6	-0.6	-1.1	-0.5	-0.9	-0.7	-0.3	-0.7	-0.8	-0.2	-0.8	-0.5	-0.9	-0.7	-0.7
Age started oral contraceptive pill	0.4	0.5	4.3	2.1	0.5	-0.7	-0.4	-0.4	-0.2	0.4	-1.0	-0.7	-0.2	-0.2	-0.3	-0.7	-0.6	-0.2	-0.6	-0.4	-1.1	-0.3
Depressed Affect (Nagel 2018)	0.3	0.7	1.4	-0.9	-1.1	0.1	-0.9	-1.0	-0.8	-0.5	-0.8	-0.9	-0.8	-1.2	-0.7	-0.9	-1.1	-0.6	-0.7	-0.5	-1.0	-0.6
Triglycerides	0.3	0.5	2.4	-1.5	-0.8	1.6	0.2	0.3	0.4	0.5	0.7	0.6	0.3	-0.2	0.2	0.6	0.4	0.4	1.1	0.9	0.7	0.4
Chronotype (morning person)	0.3	0.8	5.6	2.4	1.0	-1.3	-0.1	-0.2	-0.0	-0.6	-0.7	-0.6	0.4	0.3	0.0	-0.2	-0.8	0.3	-1.8	-0.3	-1.0	0.3
Number of treatments/medications taken	0.3	0.5	7.1	-2.7	-0.9	0.2	0.2	-0.1	-0.4	-0.4	0.4	0.1	-0.5	-0.2	-0.4	-0.1	0.2	-0.5	0.4	-0.3	0.5	-0.5
Supplements: Zinc	0.3	0.3	1.1	-1.0	-0.3	0.4	0.5	0.4	0.4	0.6	0.9	0.4	0.3	0.3	0.1	0.6	0.7	0.3	0.8	0.3	1.1	0.3
Medication: Metformin	0.3	0.4	0.8	-0.8	0.4	0.2	0.9	0.6	0.6	0.4	0.8	0.9	0.7	0.8	0.4	0.8	0.6	0.5	0.6	0.5	0.8	0.6
Diabetes (mother)	0.3	0.4	2.8	-1.7	-0.4	0.9	0.6	0.2	0.5	-0.1	0.6	0.7	0.5	0.2	0.2	0.8	0.0	0.6	0.2	0.5	0.7	0.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.4	-0.6	-0.7	1.6	0.2	-0.0	0.1	0.5	0.3	0.1	-0.0	-0.6	0.4	0.1	0.1	0.3	0.9	0.6	-0.1	-0.0
Qualifications: CSEs or equivalent	0.3	0.4	0.9	-0.7	-0.1	0.9	0.4	0.7	0.4	0.6	0.9	0.5	0.4	0.4	0.7	0.7	0.9	0.5	0.8	0.6	0.9	0.4
Alcohol usually taken with meals	0.3	0.5	3.5	1.9	1.4	-1.0	0.3	0.4	0.6	0.7	0.0	0.0	0.6	0.9	0.6	0.0	0.3	0.5	-0.2	0.1	-0.5	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.6	-0.8	0.3	0.5	1.2	0.5	0.9	0.4	1.1	1.0	0.8	0.7	0.5	0.9	0.7	0.8	0.8	0.5	0.9	0.8
Mouth/teeth dental problems	0.3	0.5	2.1	1.5	1.4	-0.4	0.3	0.7	0.6	0.7	0.1	0.2	0.6	0.8	0.9	0.3	0.4	0.7	-0.2	0.3	-0.0	0.5
Worrier / anxious feelings	0.3	0.6	0.8	-0.8	-0.9	-0.4	-0.9	-0.8	-0.8	-0.5	-0.8	-0.8	-0.8	-0.9	-0.8	-0.8	-0.9	-0.8	-0.6	-0.6	-0.8	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	0.9	-0.3	0.6	0.6	0.3	0.8	0.4	0.9	0.8	0.8	0.6	0.8	0.9	0.7	0.9	0.5	0.7	0.9	0.6	0.5
Number of live births	0.3	0.5	4.5	-2.1	-0.4	0.1	0.6	0.3	0.1	-0.1	0.8	0.6	-0.1	0.3	0.1	0.4	0.7	-0.1	0.5	-0.1	1.2	0.0
Pulse rate	0.3	0.4	0.7	0.4	-0.8	-0.4	-0.7	-0.6	-0.8	-0.5	-0.7	-0.8	-0.8	-0.7	-0.7	-0.7	-0.6	-0.6	-0.7	-0.7	-0.4	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.1	-1.1	-0.5	1.0	0.2	0.4	0.3	0.4	0.9	0.5	0.3	0.1	0.5	0.7	0.7	0.4	0.8	0.5	0.9	0.4
Lung cancer (father)	0.3	0.3	1.8	-1.4	-0.2	0.8	0.7	0.2	0.6	0.2	0.6	0.6	0.4	0.2	0.3	0.6	0.3	0.5	0.5	0.4	0.6	0.4
Tense / ‘highly strung’	0.3	0.5	1.1	-0.8	0.2	0.3	0.8	0.8	0.6	0.1	1.0	0.6	0.7	0.8	0.8	0.8	1.0	0.8	0.7	0.6	0.8	0.7
Medication: Amlodipine	0.3	0.4	0.9	-0.1	-0.4	-0.3	-0.4	-0.8	-0.4	-0.7	-0.7	-0.6	-0.5	-0.7	-0.8	-0.6	-1.0	-0.5	-0.7	-0.6	-0.7	-0.4
Medication: Omeprazole	0.3	0.3	2.1	-1.5	-1.1	0.1	-0.3	-0.7	-0.2	-0.2	-0.1	-0.1	-0.3	-0.7	-0.6	-0.1	-0.5	-0.3	0.2	-0.5	-0.0	-0.3
Chest pain or discomfort	0.3	0.5	2.3	-0.3	0.3	1.0	0.1	0.9	0.2	1.0	0.7	0.5	0.4	0.4	0.8	0.4	1.1	0.2	1.5	0.9	0.3	0.4
Family relationship satisfaction	0.3	0.4	1.5	0.9	1.2	-0.1	0.4	0.6	0.7	0.3	0.4	0.5	0.7	0.8	0.9	0.6	0.4	0.8	-0.1	0.5	0.3	0.7
Commuting to job workplace: Car/motor vehicle	0.3	0.4	0.8	0.5	0.2	0.9	0.7	0.4	0.9	0.2	0.8	0.6	0.7	0.3	0.5	0.8	0.6	0.8	0.6	0.7	0.6	0.6
Eye problems/disorders: Cataract	0.3	0.3	1.1	0.8	1.0	-0.6	0.5	0.6	0.4	0.2	0.6	0.3	0.5	1.0	0.3	0.3	0.8	0.2	0.4	0.3	0.4	0.4
Breast cancer (self-reported)	0.3	0.4	0.9	0.0	0.1	0.4	0.9	0.6	0.5	0.7	0.8	0.8	0.5	0.6	0.4	0.6	0.7	0.6	0.6	0.4	1.0	0.5
Medication: Atorvastatin	0.3	0.4	1.1	0.9	0.1	-0.7	-0.5	-0.5	-0.4	-0.8	-0.7	-0.7	-0.4	-0.4	-0.3	-0.5	-0.7	-0.4	-1.0	-0.4	-0.8	-0.4
Supplements: Calcium	0.3	0.3	0.9	0.6	-0.5	-0.2	-0.8	-0.6	-0.4	-0.1	-0.7	-0.9	-0.4	-0.7	-0.3	-0.6	-0.7	-0.3	-0.6	-0.3	-0.9	-0.5
Basal cell carcinoma (self-reported)	0.3	0.4	1.0	-0.5	-0.6	0.0	-0.9	-0.7	-0.7	-0.3	-0.8	-0.5	-0.6	-0.9	-0.4	-0.6	-0.6	-0.6	-0.1	-0.3	-1.0	-0.7
Heart disease (siblings)	0.3	0.4	1.3	1.1	1.0	-0.2	-0.3	0.8	0.3	1.1	0.5	0.1	0.6	0.8	0.8	0.3	0.8	0.3	0.2	0.6	-0.1	0.4
Alcohol drinker status: Previous	0.3	0.3	1.0	-0.6	-0.6	0.7	1.0	0.3	0.4	-0.2	0.9	0.5	0.3	0.3	-0.1	0.6	0.5	0.3	0.7	0.5	1.0	0.3
Bipolar Disorder (2018)	0.2	0.2	1.2	0.2	0.1	-1.1	-0.7	-0.0	-0.7	0.1	-0.3	-0.7	-0.5	0.1	-0.2	-0.6	0.1	-0.6	-0.4	-0.5	-0.4	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.6	3.0	1.0	0.9	-0.8	-0.7	0.9	-0.2	1.7	0.2	0.1	0.1	1.1	0.4	-0.1	1.3	-0.2	0.7	0.2	0.2	-0.1
Neuroticism (Nagel 2018)	0.2	0.5	0.9	-0.5	-0.9	-0.2	-1.0	-0.8	-0.8	-0.4	-0.8	-0.7	-0.7	-0.9	-0.6	-0.8	-0.8	-0.6	-0.4	-0.5	-1.0	-0.7
Worry (Nagel 2018)	0.2	0.3	1.1	-0.4	-0.1	1.1	0.3	0.6	0.4	0.8	0.5	0.5	0.4	0.2	0.7	0.4	0.6	0.5	0.9	0.7	0.4	0.4
Alzheimer’s Disease (in father)	0.2	0.3	0.7	0.7	-0.1	-0.8	-0.8	-0.3	-0.2	-0.0	-0.6	-0.7	-0.4	-0.3	-0.3	-0.5	-0.4	-0.3	-0.7	-0.4	-0.6	-0.4
Irritable Bowel Disease (IBD)	0.2	0.5	1.5	-0.7	-0.5	0.7	0.9	0.4	0.6	0.2	1.0	1.0	0.7	0.7	-0.2	0.9	0.5	0.4	1.2	0.6	1.1	0.7
Smoking Status	0.2	0.4	1.6	-1.3	-1.2	0.8	-0.5	-0.5	-0.4	-0.2	-0.1	0.0	-0.7	-1.0	-0.3	-0.3	-0.2	-0.5	0.5	-0.3	-0.0	-0.6
Medication for hormone replacement therapy	0.2	0.2	0.6	-0.2	0.5	0.5	0.3	0.7	0.1	0.2	0.5	0.3	0.3	0.5	0.4	0.5	0.8	0.2	0.7	0.6	0.6	0.3
Townsend deprivation index at recruitment	0.2	0.3	3.1	-1.8	-1.1	0.5	-0.2	-0.5	-0.2	-0.3	0.1	0.1	-0.1	-0.5	-0.4	0.2	-0.5	-0.0	0.1	-0.2	0.1	-0.1
Maternal smoking around birth	0.2	0.3	2.5	-1.6	-1.0	0.7	0.0	-0.3	-0.1	-0.3	0.5	0.2	-0.2	-0.4	-0.3	0.2	-0.0	-0.3	0.6	0.1	0.4	-0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.8	0.3	-0.3	-0.9	-0.3	-0.6	-0.5	-0.0	-0.5	-0.2	-0.6	-0.2	-0.9	-0.6	-0.5	-0.7	-0.5	-0.7	-0.2	-0.5
Past tobacco smoking	0.2	0.4	1.1	0.8	-0.2	-0.8	-0.0	-0.6	-0.3	-0.7	-0.8	-0.5	-0.2	-0.2	-0.8	-0.5	-1.0	-0.3	-1.0	-0.6	-0.7	-0.2
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	-0.3	-0.7	-0.8	-0.3	-0.4	-0.7	-0.3	-0.3	-0.5	-0.7	-0.4	-0.5	-0.5	-0.2	-0.7	-0.1	-0.7	-0.1	-0.8
Had menopause	0.2	0.3	1.0	-0.5	-0.0	0.9	0.6	0.2	0.5	0.6	0.3	0.7	0.4	0.2	0.1	0.4	0.3	0.3	1.0	0.6	0.4	0.4
Hip circumference	0.2	0.8	1.4	-0.1	-0.8	-1.0	-0.8	-0.9	-1.1	-0.3	-1.0	-0.9	-1.1	-0.9	-1.2	-1.0	-0.9	-1.1	-1.1	-1.1	-0.5	-1.1
Time employed in main current job	0.2	0.2	2.7	1.6	0.8	-0.6	-0.3	0.2	0.0	0.0	0.1	0.0	0.2	0.4	0.4	0.1	0.2	0.1	-0.4	0.1	-0.1	0.1
Mouth/teeth dental problems: Dentures	0.2	0.4	1.5	-1.2	-1.0	1.2	0.1	0.1	0.2	0.9	0.5	0.4	-0.1	-0.4	-0.1	0.3	0.3	0.0	1.0	0.3	0.5	0.0
Prospective memory result	0.2	0.3	2.7	-1.6	-0.9	0.3	0.3	-0.3	-0.1	-0.6	0.2	-0.3	-0.4	-0.5	-0.6	-0.2	-0.1	-0.3	0.3	-0.2	0.2	-0.3
Illnesses of mother	0.2	0.2	1.7	1.3	0.7	0.2	-0.1	0.3	0.2	0.8	-0.2	0.1	0.3	0.1	0.8	0.0	0.1	0.4	0.0	0.4	-0.4	0.5
Pulse wave Arterial Stiffness index	0.2	0.3	0.9	0.0	-0.1	0.6	0.5	0.3	0.4	0.9	0.4	0.8	0.3	0.3	0.2	0.6	0.4	0.5	0.8	0.2	0.9	0.2
Peak expiratory flow (PEF)	0.2	0.4	1.0	0.3	-0.7	0.1	-0.9	-0.8	-0.6	-0.4	-0.8	-0.8	-0.5	-0.9	-0.6	-0.7	-0.8	-0.6	-0.3	-0.3	-1.0	-0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.9	0.6	-0.1	-0.1	-0.3	-0.6	-0.1	-0.8	-0.7	-0.4	-0.1	-0.5	-0.4	-0.4	-0.8	-0.2	-0.8	-0.2	-0.9	-0.0
Pulse wave peak to peak time	0.2	0.2	0.9	0.2	0.3	-0.5	-0.5	-0.2	-0.4	-0.9	-0.4	-0.8	-0.2	-0.2	-0.1	-0.6	-0.3	-0.4	-0.7	-0.1	-1.0	-0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.8	0.1	0.1	0.9	0.1	0.3	0.3	0.7	0.4	0.4	0.4	0.0	0.6	0.3	0.4	0.3	0.7	0.5	0.0	0.5
Suffer from ‘nerves’	0.2	0.2	0.8	-0.4	-0.3	-0.7	-0.9	-0.1	-0.8	-0.1	-0.4	-0.5	-0.6	-0.3	-0.3	-0.5	-0.0	-0.7	-0.4	-0.4	-0.2	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	2.3	-1.5	-0.9	0.1	-0.4	-0.4	-0.5	-0.0	-0.2	-0.1	-0.5	-0.5	-0.5	-0.3	-0.4	-0.5	-0.1	-0.4	0.0	-0.4
Illnesses of father: Heart disease	0.2	0.3	0.8	0.4	0.9	-0.6	0.3	0.7	0.3	0.2	0.5	0.2	0.5	0.9	0.4	0.4	0.7	0.4	-0.3	0.3	0.7	0.5
Smoking status: Previous	0.2	0.3	1.6	-1.3	-0.2	0.6	0.1	0.4	0.2	0.4	0.7	0.4	0.1	0.2	0.3	0.5	0.8	0.1	0.8	0.3	0.9	0.1
Diabetes diagnosed by doctor	0.2	0.3	2.3	-1.5	0.0	-1.1	-0.3	0.0	-0.7	-0.6	0.1	-0.1	-0.4	0.3	-0.4	-0.3	0.3	-0.8	-0.3	-0.6	0.2	-0.5
Friendships satisfaction	0.2	0.3	1.1	-0.0	0.8	0.0	0.2	0.5	0.5	1.1	0.5	0.4	0.5	0.6	0.7	0.5	0.5	0.5	0.3	0.4	0.4	0.4
Commuting to job workplace: Walk	0.2	0.2	0.7	-0.4	0.2	0.2	0.4	0.3	0.3	0.9	0.4	0.5	0.5	0.5	0.1	0.4	0.1	0.4	0.2	0.4	0.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.2	-1.1	-0.3	-0.5	-0.1	0.3	-0.5	0.1	0.5	-0.2	-0.6	0.3	-0.2	-0.3	0.9	-0.7	0.8	-0.3	0.6	-0.5
Wears glasses or contact lenses	0.2	0.3	1.1	1.1	-0.1	-0.4	-0.0	-0.5	-0.3	-0.3	-0.8	-0.4	-0.2	-0.4	-0.4	-0.4	-0.8	-0.2	-0.8	-0.4	-0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.9	-0.2	0.4	0.6	0.1	0.6	0.4	1.0	0.5	0.4	0.5	0.4	0.6	0.5	0.5	0.6	0.4	0.7	0.4	0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	3.6	-1.9	-0.8	0.3	0.1	-0.2	0.0	0.2	0.4	0.4	-0.0	-0.2	-0.2	0.2	0.2	-0.1	0.8	-0.1	0.4	-0.1
HbA1C	0.1	0.1	0.6	0.8	0.4	-0.1	0.4	0.4	0.4	-0.1	0.4	0.1	0.0	0.5	0.4	-0.5	0.6	0.1	0.4	0.3	0.1	0.3
Height	0.1	1.6	10.7	3.3	2.0	-0.5	-0.1	1.1	0.4	2.9	-0.3	0.1	0.6	1.2	0.7	-0.2	0.9	0.3	0.9	0.8	-0.6	0.4
Systolic Blood Pressure	0.1	0.7	2.5	-0.0	0.2	1.6	0.5	0.9	0.9	1.0	0.9	0.5	0.8	0.4	0.9	0.9	0.8	1.0	1.1	1.3	0.5	0.9
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.0	-0.9	-0.0	-0.8	0.1	-0.3	-0.4	-1.0	-0.1	-0.1	-0.3	0.1	-0.5	-0.2	-0.2	-0.5	-0.7	-0.5	0.1	-0.3
Lung FEV1/FVC ratio	0.1	0.5	1.3	0.7	-0.1	-0.4	-1.1	-0.6	-0.7	-0.1	-1.0	-0.8	-0.6	-0.7	-0.4	-0.8	-0.7	-0.6	-0.7	-0.5	-1.0	-0.7
Average weekly spirits intake	0.1	0.1	1.0	-1.0	-0.5	0.2	-0.1	0.3	-0.3	0.0	0.3	0.2	-0.4	-0.1	0.2	-0.1	0.5	-0.4	0.3	-0.1	0.5	-0.3
Hearing difficulty/problems: Yes	0.1	0.1	0.5	-0.7	-0.5	0.3	0.0	-0.0	-0.1	-0.1	0.2	0.0	-0.2	-0.3	-0.1	-0.0	0.2	-0.2	0.4	-0.0	0.3	-0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.3	-0.2	0.0	-0.5	-0.3	-0.3	-0.5	-0.3	-0.4	-0.2	-0.3	-0.1	-0.4	-0.4	-0.2	-0.5	-0.1	-0.4	-0.4	-0.3
Systolic blood pressure, automated reading	0.1	0.4	1.9	-0.1	-0.3	1.4	0.5	0.3	0.8	0.5	0.5	0.4	0.6	-0.1	0.4	0.6	0.2	0.7	0.6	0.8	0.4	0.7
Diabetes (father)	0.1	0.1	0.3	0.1	0.5	-0.4	0.1	0.3	0.1	-0.6	0.4	-0.2	-0.0	0.4	0.2	0.0	0.4	-0.0	-0.2	-0.1	0.2	0.0
Trunk fat mass	0.1	0.5	0.8	0.2	0.7	0.6	0.8	0.9	0.5	0.6	0.8	0.9	0.8	0.9	0.6	0.8	0.8	0.7	0.3	0.8	0.9	0.8
Waist circumference	0.1	0.3	0.8	-0.9	-0.9	0.1	-0.4	-0.6	-0.6	-0.3	-0.3	-0.3	-0.6	-0.6	-0.8	-0.4	-0.4	-0.6	-0.3	-0.4	0.1	-0.6
Had other major operations	0.1	0.1	0.6	-0.4	-0.3	0.3	0.3	0.3	0.1	0.3	0.5	0.4	0.2	0.3	-0.2	0.3	0.5	0.1	0.8	0.2	0.7	0.2
Father’s age at death	0.1	0.1	0.7	-0.2	-0.4	0.3	0.6	-0.3	-0.1	0.3	-0.4	0.1	-0.1	-0.3	-0.6	-0.2	-0.5	-0.1	0.8	0.1	-0.2	-0.2
Standing height	0.1	1.0	6.8	2.6	1.2	-1.0	-1.0	0.2	-0.4	1.6	-1.2	-0.7	-0.2	0.2	-0.1	-1.0	-0.0	-0.6	0.0	-0.0	-1.4	-0.4
Exposure to tobacco smoke at home	0.1	0.1	0.8	-0.9	-0.7	-0.2	-0.1	-0.2	0.1	-0.5	0.4	-0.0	0.0	-0.1	-0.4	0.2	-0.1	-0.1	-0.1	-0.1	0.3	-0.0
Gout (self-reported)	0.1	0.2	0.9	-1.0	0.1	0.9	0.4	0.3	0.3	-0.0	0.2	0.2	0.2	0.1	0.3	0.1	0.5	0.1	0.6	0.4	0.3	0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.5	-0.4	0.3	0.2	-0.1	0.3	0.4	0.7	0.5	0.5	0.4	0.3	0.4	0.5	0.4	0.4	0.0	0.4	0.5	0.3
Number of full brothers	0.1	0.1	0.6	-0.0	-0.3	0.8	-0.2	0.2	0.1	-0.0	0.4	0.2	0.0	-0.4	0.7	0.3	0.4	0.2	0.3	0.2	0.1	0.2
Eye problems/disorders: None of the above	0.1	0.1	0.5	0.7	0.2	0.3	-0.3	0.0	-0.0	-0.4	-0.3	-0.4	0.0	-0.3	0.4	-0.1	-0.1	0.1	-0.4	0.2	-0.6	0.0
Medication: Allopurinol	0.1	0.1	0.9	-0.9	-0.1	0.4	0.2	0.1	-0.2	-0.0	0.0	0.2	-0.1	0.0	-0.2	-0.1	0.2	-0.3	0.4	0.0	0.3	-0.1
Leg fat mass (right)	0.1	0.2	1.1	-1.1	-0.6	0.9	0.5	0.1	-0.0	-0.0	0.5	0.5	0.1	-0.1	-0.1	0.4	0.2	0.1	0.2	0.3	0.9	0.2
Pulse rate, automated reading	0.1	0.2	0.3	-0.2	-0.6	-0.6	-0.6	-0.4	-0.5	-0.1	-0.3	-0.6	-0.5	-0.3	-0.5	-0.4	-0.4	-0.4	-0.6	-0.4	-0.1	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.5	0.0	-0.5	-0.0	-0.7	-0.4	-0.7	-0.0	-0.7	-0.4	-0.6	-0.5	-0.5	-0.6	-0.5	-0.7	-0.1	-0.3	-0.7	-0.6
Arm fat percentage (left)	0.1	0.4	1.3	-0.8	0.1	0.7	0.8	0.5	0.3	-0.2	0.9	0.9	0.6	0.6	0.3	0.8	0.5	0.6	-0.0	0.5	1.1	0.6
Long-standing illness, disability or infirmity	0.1	0.2	1.9	-1.4	-0.3	0.8	-0.2	0.1	-0.1	0.5	0.2	0.2	-0.0	-0.1	0.2	0.0	0.4	-0.1	0.6	0.4	-0.1	-0.1
Arm fat mass (left)	0.1	0.5	0.9	-0.7	-0.9	-0.3	-0.5	-0.7	-0.9	-0.8	-0.6	-0.4	-0.7	-0.7	-0.9	-0.6	-0.7	-0.8	-1.0	-0.7	-0.1	-0.7
High cholesterol (Self-reported)	0.1	0.1	0.4	-0.6	0.5	-0.1	0.4	0.4	0.3	-0.1	0.6	0.2	0.3	0.5	0.4	0.3	0.4	0.3	-0.1	0.2	0.4	0.3
Alcohol drinker status: Never	0.1	0.1	0.6	-0.3	-0.1	0.4	0.7	-0.1	0.3	-0.8	0.3	0.6	0.3	0.0	0.1	0.4	-0.1	0.3	0.2	0.1	0.2	0.4
Ever smoked	0.1	0.2	0.6	-0.1	0.5	0.6	-0.3	0.4	0.3	0.6	0.4	0.1	0.2	0.1	0.8	0.2	0.6	0.2	0.5	0.5	-0.0	0.3
Unable to work because of sickness or disability	0.1	0.2	0.5	-0.1	-0.5	0.2	-0.6	-0.3	-0.4	-0.7	-0.2	-0.7	-0.5	-0.6	0.1	-0.5	0.0	-0.4	-0.1	-0.0	-0.6	-0.5
Myopia	0.1	0.2	0.6	0.6	0.5	0.7	0.1	0.2	0.4	0.3	0.1	0.2	0.7	0.2	0.4	0.3	0.1	0.6	0.4	0.8	-0.3	0.6
Cholesterol lowering medication	0.1	0.1	0.8	-0.3	0.3	-0.1	0.3	0.0	0.2	-0.9	0.3	0.2	0.1	0.1	0.2	0.2	0.1	0.1	-0.0	-0.1	0.2	0.1
Leg fat mass (left)	0.1	0.3	0.9	-0.9	-0.4	0.9	0.6	0.2	0.1	0.0	0.6	0.6	0.3	0.1	-0.0	0.6	0.2	0.3	0.2	0.4	1.0	0.3
Schizophrenia vs Biploar Disorder	0.0	0.0	0.1	-0.3	0.3	-0.3	0.1	0.0	0.0	-0.3	-0.1	0.3	0.1	0.3	-0.1	-0.0	0.0	-0.2	-0.0	-0.1	0.1	0.1
Ulcerative Colitis (UC)	0.0	0.1	0.6	-0.1	-0.4	-0.5	0.1	-0.2	-0.2	-0.2	0.0	0.3	0.1	0.3	-0.7	0.1	-0.1	-0.4	0.4	-0.3	0.2	0.0
Ovarian Cancer	0.0	0.1	0.2	0.2	-0.0	0.3	0.4	0.1	0.2	-0.0	0.3	0.4	0.3	0.3	0.1	0.3	0.1	0.1	0.3	0.3	0.2	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.0	0.1	0.4	-0.6	-0.3	-0.4	-0.5	-0.1	-0.6	-0.1	-0.2	-0.3	-0.4	-0.2	-0.4	-0.3	-0.0	-0.5	-0.1	-0.4	-0.0	-0.5
Hair Pigment	0.0	1.0	4.2	-1.0	-1.9	0.2	-0.1	-1.1	-0.9	-2.0	-0.4	-0.6	-1.0	-1.4	-0.8	-0.5	-1.0	-0.8	-0.8	-0.9	-0.3	-0.9
Tanning	0.0	0.2	0.8	0.3	-0.0	-0.4	0.1	-0.6	-0.0	-0.9	-0.5	-0.3	-0.1	-0.5	-0.3	-0.4	-0.8	-0.2	-0.5	-0.6	-0.8	-0.1
Hair/balding pattern: Pattern 3	0.0	0.1	0.7	-0.8	0.1	-0.1	-0.2	0.2	-0.2	-0.0	0.1	0.2	-0.1	0.1	0.0	0.0	0.3	-0.2	-0.1	-0.1	0.3	-0.1
Arm fat mass (right)	0.0	0.2	0.5	-0.7	-0.6	-0.1	-0.2	-0.4	-0.6	-0.5	-0.3	-0.1	-0.4	-0.4	-0.6	-0.2	-0.5	-0.4	-0.7	-0.4	0.1	-0.4
Hair/balding pattern: Pattern 4	0.0	0.1	0.4	-0.2	-0.2	0.6	0.2	-0.2	0.3	0.2	-0.1	0.1	0.2	-0.3	-0.1	0.2	-0.3	0.3	0.2	0.1	-0.2	0.2
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.1	-0.1	0.3	0.1	0.0	0.1	0.0	-0.2	0.1	0.1	0.2	0.2	0.1	0.1	0.0	0.0	-0.1	0.3	-0.2	0.3
Whole body fat mass	0.0	0.1	0.3	-0.4	-0.2	0.4	0.3	0.2	-0.1	-0.1	0.3	0.3	0.1	0.1	-0.2	0.2	0.1	0.0	-0.1	0.2	0.6	0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.1	-0.0	0.3	-0.2	0.0	0.1	0.1	-0.1	0.1	-0.1	0.1	0.2	0.0	0.1	0.1	0.2	-0.3	-0.1	-0.0	0.0
Loneliness, isolation	0.0	0.1	0.6	0.1	0.1	-0.8	-0.2	-0.0	-0.1	-0.0	-0.0	-0.2	-0.0	0.3	-0.2	-0.2	-0.0	-0.3	-0.3	-0.3	-0.0	0.0
Osteoporosis (self-reported)	0.0	0.0	0.1	-0.1	0.3	-0.2	-0.1	0.1	-0.1	-0.4	0.0	-0.0	0.2	0.3	-0.1	0.3	-0.1	0.1	-0.2	0.2	0.1	0.1
Average weekly champagne plus white wine intake	0.0	0.1	0.6	0.8	0.4	-0.4	0.1	0.2	-0.1	0.1	-0.0	-0.0	0.1	0.4	-0.1	-0.1	0.1	-0.0	0.2	-0.0	-0.0	0.1

Hub : Genes

C6orf164

Models

Trait associations