[Hub]/) : Traits : Impedance of arm (right) :

chr9:93,476,005-97,136,378

Best TWAS P=4.73e-25 · Best GWAS P=5.72e-25 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPP 0.43 0.52 bslmm 525 0.51 2.3e-72 -5.7 -5.8 7.6e-09 0.65 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100128361 0.10 0.08 lasso 4 0.09 2.2e-11 -5.7 -5.8 5.0e-09 0.71 0.99 0.01 FALSE
3 CommonMind Brain Pre-frontal Cortex OGN 0.04 0.04 lasso 4 0.04 2.3e-05 -5.2 -6.9 7.2e-12 0.68 0.49 0.42 FALSE
4 GTEx Adipose Subcutaneous ECM2 0.05 0.00 lasso 4 0.00 1.2e-01 3.7 -5.5 2.9e-08 0.64 0.15 0.27 FALSE
5 GTEx Adipose Subcutaneous ANKRD19P 0.06 0.03 enet 16 0.04 2.2e-04 -2.6 5.7 1.5e-08 -0.70 0.28 0.68 FALSE
6 GTEx Adipose Visceral Omentum CENPP 0.28 0.29 enet 14 0.30 5.1e-16 -5.4 -5.4 6.4e-08 0.63 1.00 0.00 FALSE
7 GTEx Adrenal Gland CENPP 0.45 0.32 enet 21 0.31 7.5e-12 -5.7 -5.6 2.3e-08 0.63 1.00 0.00 FALSE
8 GTEx Artery Aorta NOL8 0.09 0.04 lasso 9 0.02 2.3e-02 -9.6 9.0 2.0e-19 -0.89 0.05 0.93 FALSE
9 GTEx Artery Coronary CENPP 0.16 0.22 lasso 1 0.18 1.6e-06 -5.3 -5.3 9.1e-08 0.63 0.62 0.33 FALSE
10 GTEx Artery Tibial CENPP 0.44 0.40 enet 35 0.42 7.5e-36 -5.4 -5.2 2.1e-07 0.61 1.00 0.00 FALSE
11 GTEx Artery Tibial NOL8 0.04 0.03 lasso 4 0.03 3.5e-03 -10.3 10.0 1.5e-23 -0.99 0.02 0.96 FALSE
12 GTEx Brain Caudate basal ganglia CENPP 0.37 0.30 enet 10 0.31 1.3e-09 -5.4 -5.4 6.3e-08 0.62 0.93 0.04 FALSE
13 GTEx Brain Cerebellar Hemisphere IPPK 0.17 0.22 lasso 13 0.16 6.8e-05 -9.6 -9.4 4.4e-21 0.93 0.10 0.86 FALSE
14 GTEx Brain Cerebellar Hemisphere CENPP 0.27 0.23 lasso 1 0.20 7.0e-06 -5.3 -5.3 9.1e-08 0.63 0.42 0.08 FALSE
15 GTEx Brain Cerebellum IPPK 0.12 0.01 enet 17 0.01 1.6e-01 -8.3 -6.8 1.3e-11 0.81 0.07 0.54 FALSE
16 GTEx Brain Cerebellum CENPP 0.41 0.34 lasso 6 0.32 2.5e-10 -5.4 -5.6 2.5e-08 0.64 0.98 0.01 FALSE
17 GTEx Brain Cortex CENPP 0.24 0.29 lasso 9 0.28 2.1e-08 -5.3 -5.5 3.2e-08 0.65 0.28 0.71 FALSE
18 GTEx Brain Frontal Cortex BA9 CENPP 0.47 0.30 lasso 9 0.29 1.8e-08 -5.4 -5.6 2.3e-08 0.61 0.77 0.10 FALSE
19 GTEx Brain Hypothalamus CENPP 0.35 0.22 lasso 6 0.14 4.0e-04 -5.4 -5.7 1.1e-08 0.64 0.32 0.31 FALSE
20 GTEx Brain Putamen basal ganglia CENPP 0.37 0.18 lasso 5 0.11 1.5e-03 -5.4 -5.1 3.0e-07 0.58 0.15 0.11 FALSE
21 GTEx Breast Mammary Tissue (Female) CENPP 0.10 0.12 enet 7 0.07 4.0e-03 -5.0 -5.4 5.9e-08 0.65 0.22 0.21 FALSE
22 GTEx Cells Transformed fibroblasts OGN 0.03 0.03 lasso 2 0.01 3.2e-02 -9.2 -9.2 5.0e-20 0.84 0.11 0.83 FALSE
23 GTEx Cells Transformed fibroblasts CENPP 0.27 0.16 lasso 8 0.15 1.4e-11 -5.4 -5.5 4.1e-08 0.63 1.00 0.00 FALSE
24 GTEx Cells Transformed fibroblasts PHF2 0.07 0.06 lasso 5 0.04 5.5e-04 -7.8 -7.7 1.1e-14 0.07 0.01 0.99 TRUE
25 GTEx Colon Sigmoid CENPP 0.55 0.40 lasso 5 0.39 8.8e-15 -5.7 -5.7 1.3e-08 0.63 1.00 0.00 FALSE
26 GTEx Colon Transverse CENPP 0.25 0.26 lasso 2 0.24 1.5e-11 -5.7 -5.7 1.1e-08 0.64 1.00 0.00 FALSE
27 GTEx Esophagus Gastroesophageal Junction CENPP 0.22 0.19 lasso 8 0.15 6.2e-06 -5.7 -6.3 2.3e-10 0.71 0.52 0.46 FALSE
28 GTEx Esophagus Muscularis OGN 0.07 0.03 enet 13 0.02 2.0e-02 -2.2 -5.9 4.3e-09 0.60 0.07 0.86 FALSE
29 GTEx Esophagus Muscularis CENPP 0.40 0.40 lasso 5 0.41 2.7e-26 -5.7 -5.6 2.0e-08 0.64 1.00 0.00 FALSE
30 GTEx Heart Atrial Appendage CENPP 0.41 0.40 lasso 7 0.40 1.7e-19 -5.4 -5.5 3.3e-08 0.61 1.00 0.00 FALSE
31 GTEx Heart Left Ventricle CENPP 0.12 0.15 lasso 3 0.13 2.4e-07 -5.1 -5.1 2.7e-07 0.63 0.93 0.05 FALSE
32 GTEx Liver OGN 0.13 0.03 lasso 4 0.04 3.5e-02 -5.3 -7.6 4.3e-14 0.63 0.05 0.74 FALSE
33 GTEx Liver ECM2 0.16 0.18 enet 8 0.18 7.4e-06 -9.0 9.0 2.2e-19 -0.85 0.17 0.80 FALSE
34 GTEx Liver CENPP 0.44 0.21 lasso 9 0.21 2.0e-06 -6.2 -6.2 6.8e-10 0.72 0.75 0.08 FALSE
35 GTEx Lung CENPP 0.30 0.24 lasso 8 0.27 1.1e-20 -5.7 -5.9 4.5e-09 0.63 1.00 0.00 FALSE
36 GTEx Lung NOL8 0.08 0.03 enet 15 0.04 2.3e-04 -8.3 7.9 4.1e-15 -0.88 0.03 0.97 FALSE
37 GTEx Muscle Skeletal OGN 0.03 0.02 enet 9 0.03 3.0e-04 -9.2 -9.5 2.9e-21 0.90 0.05 0.92 FALSE
38 GTEx Muscle Skeletal CENPP 0.30 0.29 lasso 6 0.30 1.0e-29 -5.7 -5.6 1.7e-08 0.65 1.00 0.00 FALSE
39 GTEx Nerve Tibial OGN 0.08 0.14 lasso 9 0.12 6.3e-09 -9.9 -9.9 4.3e-23 0.93 0.10 0.90 FALSE
40 GTEx Nerve Tibial CENPP 0.47 0.36 enet 45 0.39 7.6e-29 -5.4 -5.7 1.0e-08 0.61 1.00 0.00 FALSE
41 GTEx Nerve Tibial NOL8 0.10 0.02 enet 7 0.03 4.7e-03 -9.2 9.4 3.5e-21 -0.89 0.12 0.83 FALSE
42 GTEx Pituitary IPPK 0.16 0.07 lasso 4 0.07 8.5e-03 -8.2 -9.0 2.6e-19 0.85 0.10 0.55 FALSE
43 GTEx Pituitary CENPP 0.38 0.31 lasso 8 0.34 2.9e-09 -5.4 -5.6 2.0e-08 0.66 0.32 0.66 FALSE
44 GTEx Skin Sun Exposed Lower leg CENPP 0.20 0.06 lasso 9 0.14 2.9e-11 3.2 -6.0 1.9e-09 0.56 0.96 0.04 FALSE
45 GTEx Small Intestine Terminal Ileum CENPP 0.29 0.11 enet 11 0.10 2.9e-03 -8.6 -7.3 2.2e-13 0.71 0.17 0.46 FALSE
46 GTEx Spleen NOL8 0.29 0.24 lasso 2 0.19 1.1e-05 -7.7 7.7 1.6e-14 -0.74 0.17 0.76 FALSE
47 GTEx Stomach CENPP 0.28 0.24 lasso 6 0.22 5.0e-11 -5.7 -5.5 3.8e-08 0.61 0.98 0.02 FALSE
48 GTEx Testis NFIL3 0.47 0.33 enet 8 0.29 3.8e-13 4.9 -5.1 2.6e-07 0.06 1.00 0.00 TRUE
49 GTEx Testis NOL8 0.19 0.24 lasso 11 0.23 1.3e-10 -10.3 10.3 4.7e-25 -1.00 0.02 0.98 TRUE
50 GTEx Thyroid OGN 0.09 0.08 lasso 4 0.05 9.9e-05 -7.0 -7.7 1.3e-14 0.65 0.22 0.77 FALSE
51 GTEx Whole Blood NOL8 0.05 0.01 enet 21 0.01 3.5e-02 -9.8 7.4 2.0e-13 -0.69 0.04 0.88 FALSE
52 METSIM Adipose NOL8 0.06 0.03 blup 418 0.04 4.1e-07 -6.2 8.6 8.3e-18 -0.82 0.03 0.97 FALSE
53 METSIM Adipose ROR2 0.12 0.04 bslmm 639 0.05 3.2e-08 3.2 6.0 2.0e-09 -0.28 1.00 0.00 FALSE
54 NTR Blood ASPN 0.03 0.04 lasso 8 0.03 3.4e-11 -5.7 -6.2 7.3e-10 0.66 1.00 0.00 FALSE
55 NTR Blood CENPP 0.02 0.02 lasso 4 0.02 2.0e-07 -5.7 -8.2 2.8e-16 0.82 0.42 0.58 FALSE
56 NTR Blood ECM2 0.03 0.01 lasso 4 0.01 1.4e-04 -5.7 -5.4 5.5e-08 0.64 0.94 0.00 FALSE
57 NTR Blood IPPK 0.02 0.01 bslmm 416 0.01 9.9e-06 -9.2 -8.7 2.2e-18 0.79 0.40 0.60 FALSE
58 NTR Blood OGN 0.10 0.11 lasso 3 0.11 5.1e-33 -5.7 -5.7 1.1e-08 0.64 1.00 0.00 FALSE
59 NTR Blood OMD 0.08 0.06 lasso 19 0.05 4.5e-17 -5.4 -5.5 3.7e-08 0.64 1.00 0.00 FALSE
60 ROSMAP Brain Pre-frontal Cortex CENPP 0.51 0.53 bslmm 500 0.53 1.8e-80 -5.7 -5.5 3.5e-08 0.62 1.00 0.00 FALSE
61 YFS Blood NOL8 0.06 0.09 lasso 17 0.10 1.5e-29 -10.1 9.2 4.8e-20 -0.94 0.01 0.99 FALSE
62 The Cancer Genome Atlas Breast Invasive Carcinoma C9orf44 0.11 0.06 blup 45 0.08 1.2e-15 -3.7 5.4 5.8e-08 -0.38 1.00 0.00 FALSE
63 The Cancer Genome Atlas Breast Invasive Carcinoma CENPP 0.07 0.03 lasso 5 0.06 2.1e-11 3.2 -7.0 3.5e-12 0.58 1.00 0.00 FALSE
64 The Cancer Genome Atlas Breast Invasive Carcinoma ECM2 0.03 0.02 lasso 5 0.02 3.9e-05 5.3 -7.4 9.5e-14 0.81 0.03 0.96 FALSE
65 The Cancer Genome Atlas Breast Invasive Carcinoma OGN 0.02 0.02 lasso 1 0.02 2.7e-04 -9.9 -9.9 3.1e-23 0.94 0.10 0.86 FALSE
66 The Cancer Genome Atlas Breast Invasive Carcinoma PHF2 0.02 0.01 blup 104 0.01 4.6e-03 -8.0 -7.0 3.0e-12 0.09 0.00 0.98 FALSE
67 The Cancer Genome Atlas Esophageal Carcinoma PHF2 0.29 0.14 blup 103 0.16 1.0e-05 -7.4 -7.4 1.8e-13 0.04 0.04 0.92 FALSE
68 The Cancer Genome Atlas Glioblastoma Multiforme CENPP 0.27 0.03 lasso 6 0.08 2.6e-03 -8.0 -5.3 1.5e-07 0.54 0.16 0.07 FALSE
69 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CENPP 0.06 0.02 blup 160 0.04 6.3e-05 3.1 -6.3 3.1e-10 0.51 0.54 0.04 FALSE
70 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma OGN 0.02 0.01 blup 51 0.01 3.4e-02 -7.9 -9.1 9.4e-20 0.85 0.06 0.23 FALSE
71 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPP 0.23 0.16 lasso 8 0.16 1.3e-17 -5.7 -6.1 1.2e-09 0.65 1.00 0.00 FALSE
72 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CENPP 0.23 0.16 lasso 6 0.16 1.9e-09 -5.7 -5.7 1.3e-08 0.64 0.99 0.00 FALSE
73 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LOC100128076 0.12 0.00 enet 8 0.04 4.0e-03 -3.7 -5.3 1.1e-07 0.40 0.01 0.71 FALSE
74 The Cancer Genome Atlas Brain Lower Grade Glioma CENPP 0.33 0.28 lasso 8 0.28 1.6e-31 -5.7 -5.7 9.4e-09 0.66 1.00 0.00 FALSE
75 The Cancer Genome Atlas Liver Hepatocellular Carcinoma OGN 0.07 0.08 lasso 1 0.06 8.0e-04 -9.7 -9.7 4.1e-22 0.90 0.04 0.86 FALSE
76 The Cancer Genome Atlas Lung Adenocarcinoma CENPP 0.14 0.08 lasso 5 0.07 2.9e-08 -5.7 -5.8 7.3e-09 0.60 1.00 0.00 FALSE
77 The Cancer Genome Atlas Lung Adenocarcinoma OGN 0.07 0.12 blup 52 0.14 1.2e-15 -9.7 -9.9 4.4e-23 0.94 0.12 0.88 FALSE
78 The Cancer Genome Atlas Lung Adenocarcinoma OMD 0.04 0.06 lasso 3 0.05 1.1e-06 -9.7 -9.6 5.5e-22 0.90 0.13 0.86 FALSE
79 The Cancer Genome Atlas Lung Adenocarcinoma PHF2 0.07 0.03 blup 104 0.05 1.9e-06 -7.4 -6.5 9.9e-11 -0.02 0.07 0.91 FALSE
80 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CENPP 0.06 0.04 blup 160 0.05 5.6e-06 3.1 -7.3 3.0e-13 0.62 0.73 0.10 FALSE
81 The Cancer Genome Atlas Lung Squamous Cell Carcinoma OGN 0.02 0.02 blup 52 0.02 2.8e-03 7.7 -9.8 7.1e-23 0.92 0.10 0.72 FALSE
82 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma CENPP 0.10 0.01 blup 161 0.04 6.3e-04 -2.1 -6.1 7.9e-10 0.51 0.26 0.12 FALSE
83 The Cancer Genome Atlas Pancreatic Adenocarcinoma C9orf44 0.27 0.05 lasso 6 0.10 7.4e-05 -6.1 5.8 7.6e-09 -0.49 0.13 0.16 FALSE
84 The Cancer Genome Atlas Pancreatic Adenocarcinoma OGN 0.05 0.02 blup 52 0.03 2.4e-02 7.7 -9.9 6.5e-23 0.92 0.03 0.63 FALSE
85 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CENPP 0.14 0.04 lasso 12 0.03 1.9e-02 -5.7 -6.0 2.3e-09 0.69 0.11 0.39 FALSE
86 The Cancer Genome Atlas Prostate Adenocarcinoma CENPP 0.29 0.19 lasso 13 0.19 4.5e-19 -5.4 -6.6 3.0e-11 0.72 1.00 0.00 FALSE
87 The Cancer Genome Atlas Prostate Adenocarcinoma OGN 0.16 0.01 enet 16 0.05 5.8e-06 -9.6 -5.5 3.2e-08 0.52 0.06 0.34 FALSE
88 The Cancer Genome Atlas Thyroid Carcinoma CENPP 0.22 0.15 blup 158 0.19 3.3e-18 -5.0 -6.0 1.8e-09 0.62 1.00 0.00 FALSE
89 The Cancer Genome Atlas Thyroid Carcinoma IPPK 0.03 0.04 blup 50 0.04 6.7e-05 4.6 -6.0 1.8e-09 0.51 0.69 0.04 FALSE
90 The Cancer Genome Atlas Thyroid Carcinoma NOL8 0.02 0.01 blup 38 0.02 7.3e-03 -8.0 10.1 9.2e-24 -0.94 0.02 0.74 FALSE