[Hub]/) : Traits : Impedance of arm (right) : ← →

chr9:93,476,005-97,136,378

Best TWAS P=4.73e-25 · Best GWAS P=5.72e-25 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
49	GTEx	Testis	NOL8	0.19	0.24	lasso	11	0.23	1.3e-10	-10.3	10.3	4.7e-25	-1.00	0.02	0.98	TRUE
24	GTEx	Cells Transformed fibroblasts	PHF2	0.07	0.06	lasso	5	0.04	5.5e-04	-7.8	-7.7	1.1e-14	0.07	0.01	0.99	TRUE
48	GTEx	Testis	NFIL3	0.47	0.33	enet	8	0.29	3.8e-13	4.9	-5.1	2.6e-07	0.06	1.00	0.00	TRUE
90	The Cancer Genome Atlas	Thyroid Carcinoma	NOL8	0.02	0.01	blup	38	0.02	7.3e-03	-8.0	10.1	9.2e-24	-0.94	0.02	0.74	FALSE
11	GTEx	Artery Tibial	NOL8	0.04	0.03	lasso	4	0.03	3.5e-03	-10.3	10.0	1.5e-23	-0.99	0.02	0.96	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	OGN	0.02	0.02	lasso	1	0.02	2.7e-04	-9.9	-9.9	3.1e-23	0.94	0.10	0.86	FALSE
39	GTEx	Nerve Tibial	OGN	0.08	0.14	lasso	9	0.12	6.3e-09	-9.9	-9.9	4.3e-23	0.93	0.10	0.90	FALSE
77	The Cancer Genome Atlas	Lung Adenocarcinoma	OGN	0.07	0.12	blup	52	0.14	1.2e-15	-9.7	-9.9	4.4e-23	0.94	0.12	0.88	FALSE
84	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	OGN	0.05	0.02	blup	52	0.03	2.4e-02	7.7	-9.9	6.5e-23	0.92	0.03	0.63	FALSE
81	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	OGN	0.02	0.02	blup	52	0.02	2.8e-03	7.7	-9.8	7.1e-23	0.92	0.10	0.72	FALSE
75	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	OGN	0.07	0.08	lasso	1	0.06	8.0e-04	-9.7	-9.7	4.1e-22	0.90	0.04	0.86	FALSE
78	The Cancer Genome Atlas	Lung Adenocarcinoma	OMD	0.04	0.06	lasso	3	0.05	1.1e-06	-9.7	-9.6	5.5e-22	0.90	0.13	0.86	FALSE
37	GTEx	Muscle Skeletal	OGN	0.03	0.02	enet	9	0.03	3.0e-04	-9.2	-9.5	2.9e-21	0.90	0.05	0.92	FALSE
41	GTEx	Nerve Tibial	NOL8	0.10	0.02	enet	7	0.03	4.7e-03	-9.2	9.4	3.5e-21	-0.89	0.12	0.83	FALSE
13	GTEx	Brain Cerebellar Hemisphere	IPPK	0.17	0.22	lasso	13	0.16	6.8e-05	-9.6	-9.4	4.4e-21	0.93	0.10	0.86	FALSE
61	YFS	Blood	NOL8	0.06	0.09	lasso	17	0.10	1.5e-29	-10.1	9.2	4.8e-20	-0.94	0.01	0.99	FALSE
22	GTEx	Cells Transformed fibroblasts	OGN	0.03	0.03	lasso	2	0.01	3.2e-02	-9.2	-9.2	5.0e-20	0.84	0.11	0.83	FALSE
70	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	OGN	0.02	0.01	blup	51	0.01	3.4e-02	-7.9	-9.1	9.4e-20	0.85	0.06	0.23	FALSE
8	GTEx	Artery Aorta	NOL8	0.09	0.04	lasso	9	0.02	2.3e-02	-9.6	9.0	2.0e-19	-0.89	0.05	0.93	FALSE
33	GTEx	Liver	ECM2	0.16	0.18	enet	8	0.18	7.4e-06	-9.0	9.0	2.2e-19	-0.85	0.17	0.80	FALSE
42	GTEx	Pituitary	IPPK	0.16	0.07	lasso	4	0.07	8.5e-03	-8.2	-9.0	2.6e-19	0.85	0.10	0.55	FALSE
57	NTR	Blood	IPPK	0.02	0.01	bslmm	416	0.01	9.9e-06	-9.2	-8.7	2.2e-18	0.79	0.40	0.60	FALSE
52	METSIM	Adipose	NOL8	0.06	0.03	blup	418	0.04	4.1e-07	-6.2	8.6	8.3e-18	-0.82	0.03	0.97	FALSE
55	NTR	Blood	CENPP	0.02	0.02	lasso	4	0.02	2.0e-07	-5.7	-8.2	2.8e-16	0.82	0.42	0.58	FALSE
36	GTEx	Lung	NOL8	0.08	0.03	enet	15	0.04	2.3e-04	-8.3	7.9	4.1e-15	-0.88	0.03	0.97	FALSE
50	GTEx	Thyroid	OGN	0.09	0.08	lasso	4	0.05	9.9e-05	-7.0	-7.7	1.3e-14	0.65	0.22	0.77	FALSE
46	GTEx	Spleen	NOL8	0.29	0.24	lasso	2	0.19	1.1e-05	-7.7	7.7	1.6e-14	-0.74	0.17	0.76	FALSE
32	GTEx	Liver	OGN	0.13	0.03	lasso	4	0.04	3.5e-02	-5.3	-7.6	4.3e-14	0.63	0.05	0.74	FALSE
64	The Cancer Genome Atlas	Breast Invasive Carcinoma	ECM2	0.03	0.02	lasso	5	0.02	3.9e-05	5.3	-7.4	9.5e-14	0.81	0.03	0.96	FALSE
67	The Cancer Genome Atlas	Esophageal Carcinoma	PHF2	0.29	0.14	blup	103	0.16	1.0e-05	-7.4	-7.4	1.8e-13	0.04	0.04	0.92	FALSE
51	GTEx	Whole Blood	NOL8	0.05	0.01	enet	21	0.01	3.5e-02	-9.8	7.4	2.0e-13	-0.69	0.04	0.88	FALSE
45	GTEx	Small Intestine Terminal Ileum	CENPP	0.29	0.11	enet	11	0.10	2.9e-03	-8.6	-7.3	2.2e-13	0.71	0.17	0.46	FALSE
80	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CENPP	0.06	0.04	blup	160	0.05	5.6e-06	3.1	-7.3	3.0e-13	0.62	0.73	0.10	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	PHF2	0.02	0.01	blup	104	0.01	4.6e-03	-8.0	-7.0	3.0e-12	0.09	0.00	0.98	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	CENPP	0.07	0.03	lasso	5	0.06	2.1e-11	3.2	-7.0	3.5e-12	0.58	1.00	0.00	FALSE
3	CommonMind	Brain Pre-frontal Cortex	OGN	0.04	0.04	lasso	4	0.04	2.3e-05	-5.2	-6.9	7.2e-12	0.68	0.49	0.42	FALSE
15	GTEx	Brain Cerebellum	IPPK	0.12	0.01	enet	17	0.01	1.6e-01	-8.3	-6.8	1.3e-11	0.81	0.07	0.54	FALSE
86	The Cancer Genome Atlas	Prostate Adenocarcinoma	CENPP	0.29	0.19	lasso	13	0.19	4.5e-19	-5.4	-6.6	3.0e-11	0.72	1.00	0.00	FALSE
79	The Cancer Genome Atlas	Lung Adenocarcinoma	PHF2	0.07	0.03	blup	104	0.05	1.9e-06	-7.4	-6.5	9.9e-11	-0.02	0.07	0.91	FALSE
27	GTEx	Esophagus Gastroesophageal Junction	CENPP	0.22	0.19	lasso	8	0.15	6.2e-06	-5.7	-6.3	2.3e-10	0.71	0.52	0.46	FALSE
69	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPP	0.06	0.02	blup	160	0.04	6.3e-05	3.1	-6.3	3.1e-10	0.51	0.54	0.04	FALSE
34	GTEx	Liver	CENPP	0.44	0.21	lasso	9	0.21	2.0e-06	-6.2	-6.2	6.8e-10	0.72	0.75	0.08	FALSE
54	NTR	Blood	ASPN	0.03	0.04	lasso	8	0.03	3.4e-11	-5.7	-6.2	7.3e-10	0.66	1.00	0.00	FALSE
82	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CENPP	0.10	0.01	blup	161	0.04	6.3e-04	-2.1	-6.1	7.9e-10	0.51	0.26	0.12	FALSE
71	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CENPP	0.23	0.16	lasso	8	0.16	1.3e-17	-5.7	-6.1	1.2e-09	0.65	1.00	0.00	FALSE
88	The Cancer Genome Atlas	Thyroid Carcinoma	CENPP	0.22	0.15	blup	158	0.19	3.3e-18	-5.0	-6.0	1.8e-09	0.62	1.00	0.00	FALSE
89	The Cancer Genome Atlas	Thyroid Carcinoma	IPPK	0.03	0.04	blup	50	0.04	6.7e-05	4.6	-6.0	1.8e-09	0.51	0.69	0.04	FALSE
44	GTEx	Skin Sun Exposed Lower leg	CENPP	0.20	0.06	lasso	9	0.14	2.9e-11	3.2	-6.0	1.9e-09	0.56	0.96	0.04	FALSE
53	METSIM	Adipose	ROR2	0.12	0.04	bslmm	639	0.05	3.2e-08	3.2	6.0	2.0e-09	-0.28	1.00	0.00	FALSE
85	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CENPP	0.14	0.04	lasso	12	0.03	1.9e-02	-5.7	-6.0	2.3e-09	0.69	0.11	0.39	FALSE
28	GTEx	Esophagus Muscularis	OGN	0.07	0.03	enet	13	0.02	2.0e-02	-2.2	-5.9	4.3e-09	0.60	0.07	0.86	FALSE
35	GTEx	Lung	CENPP	0.30	0.24	lasso	8	0.27	1.1e-20	-5.7	-5.9	4.5e-09	0.63	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LOC100128361	0.10	0.08	lasso	4	0.09	2.2e-11	-5.7	-5.8	5.0e-09	0.71	0.99	0.01	FALSE
76	The Cancer Genome Atlas	Lung Adenocarcinoma	CENPP	0.14	0.08	lasso	5	0.07	2.9e-08	-5.7	-5.8	7.3e-09	0.60	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CENPP	0.43	0.52	bslmm	525	0.51	2.3e-72	-5.7	-5.8	7.6e-09	0.65	1.00	0.00	FALSE
83	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C9orf44	0.27	0.05	lasso	6	0.10	7.4e-05	-6.1	5.8	7.6e-09	-0.49	0.13	0.16	FALSE
74	The Cancer Genome Atlas	Brain Lower Grade Glioma	CENPP	0.33	0.28	lasso	8	0.28	1.6e-31	-5.7	-5.7	9.4e-09	0.66	1.00	0.00	FALSE
40	GTEx	Nerve Tibial	CENPP	0.47	0.36	enet	45	0.39	7.6e-29	-5.4	-5.7	1.0e-08	0.61	1.00	0.00	FALSE
19	GTEx	Brain Hypothalamus	CENPP	0.35	0.22	lasso	6	0.14	4.0e-04	-5.4	-5.7	1.1e-08	0.64	0.32	0.31	FALSE
26	GTEx	Colon Transverse	CENPP	0.25	0.26	lasso	2	0.24	1.5e-11	-5.7	-5.7	1.1e-08	0.64	1.00	0.00	FALSE
58	NTR	Blood	OGN	0.10	0.11	lasso	3	0.11	5.1e-33	-5.7	-5.7	1.1e-08	0.64	1.00	0.00	FALSE
25	GTEx	Colon Sigmoid	CENPP	0.55	0.40	lasso	5	0.39	8.8e-15	-5.7	-5.7	1.3e-08	0.63	1.00	0.00	FALSE
72	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CENPP	0.23	0.16	lasso	6	0.16	1.9e-09	-5.7	-5.7	1.3e-08	0.64	0.99	0.00	FALSE
5	GTEx	Adipose Subcutaneous	ANKRD19P	0.06	0.03	enet	16	0.04	2.2e-04	-2.6	5.7	1.5e-08	-0.70	0.28	0.68	FALSE
38	GTEx	Muscle Skeletal	CENPP	0.30	0.29	lasso	6	0.30	1.0e-29	-5.7	-5.6	1.7e-08	0.65	1.00	0.00	FALSE
29	GTEx	Esophagus Muscularis	CENPP	0.40	0.40	lasso	5	0.41	2.7e-26	-5.7	-5.6	2.0e-08	0.64	1.00	0.00	FALSE
43	GTEx	Pituitary	CENPP	0.38	0.31	lasso	8	0.34	2.9e-09	-5.4	-5.6	2.0e-08	0.66	0.32	0.66	FALSE
7	GTEx	Adrenal Gland	CENPP	0.45	0.32	enet	21	0.31	7.5e-12	-5.7	-5.6	2.3e-08	0.63	1.00	0.00	FALSE
18	GTEx	Brain Frontal Cortex BA9	CENPP	0.47	0.30	lasso	9	0.29	1.8e-08	-5.4	-5.6	2.3e-08	0.61	0.77	0.10	FALSE
16	GTEx	Brain Cerebellum	CENPP	0.41	0.34	lasso	6	0.32	2.5e-10	-5.4	-5.6	2.5e-08	0.64	0.98	0.01	FALSE
4	GTEx	Adipose Subcutaneous	ECM2	0.05	0.00	lasso	4	0.00	1.2e-01	3.7	-5.5	2.9e-08	0.64	0.15	0.27	FALSE
17	GTEx	Brain Cortex	CENPP	0.24	0.29	lasso	9	0.28	2.1e-08	-5.3	-5.5	3.2e-08	0.65	0.28	0.71	FALSE
87	The Cancer Genome Atlas	Prostate Adenocarcinoma	OGN	0.16	0.01	enet	16	0.05	5.8e-06	-9.6	-5.5	3.2e-08	0.52	0.06	0.34	FALSE
30	GTEx	Heart Atrial Appendage	CENPP	0.41	0.40	lasso	7	0.40	1.7e-19	-5.4	-5.5	3.3e-08	0.61	1.00	0.00	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	CENPP	0.51	0.53	bslmm	500	0.53	1.8e-80	-5.7	-5.5	3.5e-08	0.62	1.00	0.00	FALSE
59	NTR	Blood	OMD	0.08	0.06	lasso	19	0.05	4.5e-17	-5.4	-5.5	3.7e-08	0.64	1.00	0.00	FALSE
47	GTEx	Stomach	CENPP	0.28	0.24	lasso	6	0.22	5.0e-11	-5.7	-5.5	3.8e-08	0.61	0.98	0.02	FALSE
23	GTEx	Cells Transformed fibroblasts	CENPP	0.27	0.16	lasso	8	0.15	1.4e-11	-5.4	-5.5	4.1e-08	0.63	1.00	0.00	FALSE
56	NTR	Blood	ECM2	0.03	0.01	lasso	4	0.01	1.4e-04	-5.7	-5.4	5.5e-08	0.64	0.94	0.00	FALSE
62	The Cancer Genome Atlas	Breast Invasive Carcinoma	C9orf44	0.11	0.06	blup	45	0.08	1.2e-15	-3.7	5.4	5.8e-08	-0.38	1.00	0.00	FALSE
21	GTEx	Breast Mammary Tissue (Female)	CENPP	0.10	0.12	enet	7	0.07	4.0e-03	-5.0	-5.4	5.9e-08	0.65	0.22	0.21	FALSE
12	GTEx	Brain Caudate basal ganglia	CENPP	0.37	0.30	enet	10	0.31	1.3e-09	-5.4	-5.4	6.3e-08	0.62	0.93	0.04	FALSE
6	GTEx	Adipose Visceral Omentum	CENPP	0.28	0.29	enet	14	0.30	5.1e-16	-5.4	-5.4	6.4e-08	0.63	1.00	0.00	FALSE
9	GTEx	Artery Coronary	CENPP	0.16	0.22	lasso	1	0.18	1.6e-06	-5.3	-5.3	9.1e-08	0.63	0.62	0.33	FALSE
14	GTEx	Brain Cerebellar Hemisphere	CENPP	0.27	0.23	lasso	1	0.20	7.0e-06	-5.3	-5.3	9.1e-08	0.63	0.42	0.08	FALSE
73	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LOC100128076	0.12	0.00	enet	8	0.04	4.0e-03	-3.7	-5.3	1.1e-07	0.40	0.01	0.71	FALSE
68	The Cancer Genome Atlas	Glioblastoma Multiforme	CENPP	0.27	0.03	lasso	6	0.08	2.6e-03	-8.0	-5.3	1.5e-07	0.54	0.16	0.07	FALSE
10	GTEx	Artery Tibial	CENPP	0.44	0.40	enet	35	0.42	7.5e-36	-5.4	-5.2	2.1e-07	0.61	1.00	0.00	FALSE
31	GTEx	Heart Left Ventricle	CENPP	0.12	0.15	lasso	3	0.13	2.4e-07	-5.1	-5.1	2.7e-07	0.63	0.93	0.05	FALSE
20	GTEx	Brain Putamen basal ganglia	CENPP	0.37	0.18	lasso	5	0.11	1.5e-03	-5.4	-5.1	3.0e-07	0.58	0.15	0.11	FALSE