TWAS hub - OGN

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0380	0.0180	2.5e-04	0.036	0.030	0.029	0.027	0.037	3.2e-05	1.2e-04	1.5e-04	2.5e-04	2.3e-05
2	GTEx	Artery Tibial	0.0993	0.0513	7.0e-03	0.019	NA	0.008	NA	0.020	1.2e-02	NA	7.1e-02	NA	1.0e-02
3	GTEx	Brain Caudate basal ganglia	0.1540	0.0770	4.7e-03	-0.010	NA	0.022	NA	-0.004	9.6e-01	NA	7.7e-02	NA	4.3e-01
4	GTEx	Cells Transformed fibroblasts	0.0320	0.0160	3.4e-03	0.025	NA	0.007	NA	0.013	4.9e-03	NA	9.5e-02	NA	3.2e-02
5	GTEx	Esophagus Muscularis	0.0690	0.0350	1.3e-03	0.029	NA	0.020	NA	0.018	6.8e-03	NA	2.0e-02	NA	2.7e-02
6	GTEx	Heart Atrial Appendage	0.0690	0.0400	9.0e-03	0.004	NA	0.001	NA	-0.003	1.9e-01	NA	3.0e-01	NA	4.4e-01
7	GTEx	Liver	0.1260	0.0610	3.0e-03	0.027	NA	0.014	NA	0.036	5.9e-02	NA	1.3e-01	NA	3.5e-02
8	GTEx	Muscle Skeletal	0.0320	0.0174	2.0e-03	0.022	NA	0.033	NA	0.030	2.8e-03	NA	3.1e-04	NA	6.0e-04
9	GTEx	Nerve Tibial	0.0840	0.0296	8.6e-08	0.135	NA	0.102	NA	0.122	9.0e-10	NA	1.2e-07	NA	6.3e-09
10	GTEx	Thyroid	0.0930	0.0400	7.8e-05	0.076	NA	0.046	NA	0.050	2.0e-06	NA	2.0e-04	NA	9.9e-05
11	NTR	Blood	0.1024	0.0257	0.0e+00	0.110	0.094	0.106	0.106	0.108	1.7e-33	8.0e-29	2.3e-32	3.0e-32	5.1e-33
12	TCGA	Breast Invasive Carcinoma	0.0162	0.0107	3.0e-04	0.017	0.014	0.006	NA	0.016	1.4e-04	5.2e-04	1.8e-02	NA	2.7e-04
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0234	0.0170	6.7e-03	0.009	0.008	0.005	NA	0.004	2.7e-02	3.4e-02	8.4e-02	NA	9.5e-02
14	TCGA	Liver Hepatocellular Carcinoma	0.0700	0.0440	1.3e-03	0.079	0.049	0.059	NA	0.061	1.5e-04	2.5e-03	9.3e-04	NA	8.0e-04
15	TCGA	Lung Adenocarcinoma	0.0748	0.0317	8.9e-16	0.123	0.136	0.129	NA	0.126	3.0e-14	1.2e-15	7.1e-15	NA	1.5e-14
16	TCGA	Lung Squamous Cell Carcinoma	0.0214	0.0131	1.2e-03	0.018	0.019	0.018	NA	0.000	3.1e-03	2.8e-03	3.8e-03	NA	3.4e-01
17	TCGA	Pancreatic Adenocarcinoma	0.0540	0.0340	6.4e-03	0.017	0.028	0.015	NA	0.014	6.0e-02	2.4e-02	7.5e-02	NA	8.1e-02
18	TCGA	Prostate Adenocarcinoma	0.1643	0.0763	5.3e-05	0.007	0.024	0.050	NA	0.030	5.3e-02	1.2e-03	5.8e-06	NA	3.8e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11	12	13	14	15	16	17	18
Impedance of arm (right)	13.5	62.8	98.6	-6.9	-2.7	-4.8	-9.2	-5.9	-7.6	-9.5	-9.9	-7.7	-5.7	-9.9	-9.1	-9.7	-9.9	-9.8	-9.9	-5.5
Impedance of arm (left)	12.6	58.4	94.4	-6.6	-2.9	-4.7	-8.8	-5.6	-6.9	-9.1	-9.6	-7.5	-5.4	-9.7	-8.9	-9.2	-9.5	-9.6	-9.6	-5.2
Impedance of whole body	10.0	50.8	80.1	-6.8	-3.0	-5.0	-8.5	-5.4	-5.8	-8.1	-9.0	-6.4	-5.4	-8.9	-8.5	-8.4	-8.8	-8.9	-8.9	-5.2
Waist Hip Ratio (WHR)	7.4	33.5	56.2	-5.0	-3.8	-7.3	-6.1	-5.3	-5.1	-6.2	-6.6	-4.6	-3.9	-6.6	-7.4	-6.2	-6.9	-7.2	-7.5	-2.7
Lung FVC	5.6	28.5	46.4	4.8	4.0	2.9	6.2	4.3	4.2	5.8	6.5	4.9	4.0	6.4	6.7	6.3	6.6	6.7	6.8	4.0
Impedance of leg (left)	4.8	23.1	37.0	-5.6	-2.0	-4.3	-6.1	-3.6	-3.1	-4.9	-5.9	-3.7	-3.8	-5.6	-6.0	-5.4	-5.8	-5.9	-5.8	-4.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.8	10.2	20.3	1.9	2.5	2.2	3.6	4.5	3.4	3.7	3.7	4.1	1.1	3.5	3.3	3.8	3.5	3.6	3.6	1.9
Glaucoma (self-reported)	4.4	5.2	9.2	-1.9	-1.1	-1.1	-2.4	-1.6	-2.4	-2.9	-2.7	-2.0	-1.3	-2.6	-3.0	-2.2	-2.7	-3.0	-3.0	-2.5
Mother’s age at death	4.3	5.3	11.3	1.1	-1.8	0.6	3.1	0.8	2.3	2.8	2.9	3.4	0.9	2.8	2.1	3.3	2.8	2.6	2.6	2.0
Height	4.0	77.2	158.8	-7.0	-1.6	1.0	-10.0	-5.7	-9.4	-10.9	-10.5	-9.6	-7.6	-10.4	-9.2	-12.6	-11.7	-10.3	-10.7	-5.2
Impedance of leg (right)	4.0	19.2	30.6	-5.3	-1.8	-4.0	-5.5	-3.3	-2.8	-4.5	-5.4	-3.2	-3.7	-5.1	-5.5	-4.9	-5.4	-5.3	-5.3	-3.3
Number of full sisters	3.8	4.7	11.4	-1.3	-2.0	-0.6	-1.9	-2.3	-2.0	-2.9	-2.2	-2.5	-1.2	-2.4	-2.1	-2.5	-2.4	-2.3	-2.4	-3.4
Osteoarthritis (self-reported)	3.5	4.5	7.7	2.1	2.1	0.6	2.8	1.5	2.3	2.4	2.7	1.6	1.5	2.5	2.5	2.1	2.4	2.5	2.4	1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	4.0	9.7	-0.7	-0.7	0.2	-2.3	-1.0	-2.4	-2.7	-2.4	-3.1	-0.2	-2.3	-2.1	-2.0	-2.1	-2.4	-2.4	-2.2
Supplements: Glucosamine	3.0	3.9	6.7	1.3	0.6	1.7	1.9	1.3	2.5	2.4	2.2	2.4	0.7	2.3	2.4	1.8	2.2	2.5	2.6	2.5
Guilty feelings	3.0	4.6	9.2	1.1	0.5	1.1	2.6	2.1	2.8	2.8	2.5	3.0	-0.1	2.4	2.1	2.2	2.0	2.4	2.3	2.8
Eye problems/disorders: Glaucoma	3.0	3.6	7.7	-1.6	-0.5	-1.4	-2.0	-1.0	-1.6	-2.4	-2.5	-1.8	-0.5	-2.5	-2.7	-1.4	-2.1	-2.8	-2.7	-1.3
Neuroticism (2016)	2.9	4.1	9.9	1.7	1.1	-0.2	2.4	1.0	3.1	2.5	2.4	2.1	1.2	2.2	2.0	2.7	2.3	2.3	2.2	1.9
Standing height	2.8	27.8	51.0	-3.8	-0.6	0.2	-6.1	-4.2	-6.5	-6.5	-6.3	-6.3	-3.6	-6.2	-5.3	-7.1	-6.7	-6.1	-6.2	-4.1
Emphysema/chronic bronchitis	2.8	3.1	8.0	-0.6	-1.6	-1.7	-1.8	-2.6	-2.8	-2.3	-1.8	-2.3	-0.2	-1.8	-1.3	-1.7	-1.6	-1.7	-1.6	-1.8
Medication: Cholesterol lowering	2.7	4.2	15.3	-1.8	-3.9	-2.6	-1.3	-2.8	-1.2	-1.9	-1.9	-0.5	-1.9	-2.1	-2.3	-1.5	-2.0	-2.2	-2.3	-1.1
Systolic Blood Pressure	2.5	12.5	24.4	-3.1	-1.1	-1.8	-4.3	-3.9	-2.6	-4.1	-4.8	-2.9	-2.0	-4.9	-4.1	-3.4	-4.0	-4.6	-4.2	-3.2
Eye problems/disorders: None of the above	2.5	2.9	5.7	2.4	1.4	0.4	1.8	1.5	1.4	1.9	2.0	0.5	1.9	2.0	1.8	1.7	1.9	1.9	1.7	2.2
Commuting to job workplace: Walk	2.5	2.7	5.4	-0.9	-0.6	-0.3	-2.1	-0.1	-2.1	-2.2	-1.9	-2.3	-0.1	-1.8	-2.1	-1.9	-1.9	-2.1	-2.1	-1.0
Mean Putamen Volume	2.4	2.8	6.4	-1.7	-1.1	0.4	-2.4	0.0	-0.7	-1.9	-2.0	-1.5	-1.8	-1.8	-1.5	-2.5	-2.1	-1.7	-1.6	-2.1
Pulse wave peak to peak time	2.4	2.8	6.5	-2.5	1.0	-0.1	-2.1	0.6	-0.6	-1.7	-2.3	-0.6	-1.9	-2.3	-2.2	-1.3	-2.0	-2.2	-2.0	-1.5
Comparative height size at age 10	2.4	13.1	24.6	-1.9	-0.7	0.2	-4.1	-3.7	-4.9	-5.0	-4.3	-4.7	-1.7	-4.3	-3.3	-4.5	-4.2	-4.1	-4.0	-3.0
Mouth/teeth dental problems: Mouth ulcers	2.4	3.9	6.6	2.5	2.3	1.8	2.3	1.6	0.0	2.0	2.5	0.7	2.3	2.6	1.9	2.1	2.2	2.1	1.9	1.8
Bipolar Disorder (2011)	2.2	2.1	3.6	-1.0	-1.4	-0.1	-1.8	-1.6	-1.7	-1.6	-1.9	-1.8	-0.4	-1.8	-1.5	-1.5	-1.6	-1.7	-1.6	-0.8
Body mass index (BMI)	2.2	9.2	17.0	4.1	1.6	0.9	4.1	1.3	2.0	2.9	3.7	1.9	3.6	3.3	3.6	4.1	4.1	3.5	3.5	2.0
Number of operations (self-reported)	2.2	3.3	5.9	1.5	1.7	-1.5	2.1	0.8	1.9	1.9	2.2	1.3	1.7	2.3	1.7	2.4	2.2	2.0	2.0	2.0
Bipolar Disorder (2018)	2.1	3.4	6.4	-1.1	-1.8	-0.8	-1.9	-1.5	-1.1	-2.2	-2.3	-1.4	-1.6	-2.5	-2.3	-2.0	-2.3	-2.5	-2.5	-0.9
Fasting Glucose	2.1	2.6	5.4	-1.2	-0.4	-1.4	-1.7	-1.9	-0.0	-2.3	-1.9	-2.1	-1.1	-2.2	-1.5	-1.9	-1.9	-1.9	-1.9	-0.6
LDL Cholesterol	2.1	3.3	7.5	-2.1	-0.2	-0.9	-2.7	-1.2	-1.5	-2.1	-2.3	-1.8	-1.1	-1.9	-2.1	-2.2	-2.1	-2.0	-1.9	-2.0
Serious illness, injury or assault to yourself	2.1	2.5	6.8	1.0	1.1	-0.5	2.0	1.1	2.0	1.9	1.9	2.0	1.4	1.7	1.2	2.6	2.1	1.6	1.6	0.4
Hayfever/allergic rhinitis (self-reported)	2.1	2.7	5.3	1.4	0.5	1.3	1.5	2.3	1.2	1.8	1.8	1.5	0.7	1.9	2.2	1.5	1.8	2.1	2.2	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.5	7.5	0.8	0.1	0.5	1.9	1.6	2.7	2.0	1.8	2.4	0.1	1.7	1.5	1.7	1.7	1.8	1.7	0.7
Sitting height	2.0	13.9	22.8	-2.7	-1.1	1.1	-4.5	-2.9	-4.3	-4.8	-4.8	-4.4	-1.9	-4.8	-3.8	-4.3	-4.3	-4.4	-4.2	-3.7
Alzheimer’s Disease (in father)	1.9	2.1	4.1	-1.2	-2.0	-0.2	-1.4	-1.0	-1.4	-1.7	-1.9	-0.9	-0.9	-2.0	-1.8	-1.2	-1.5	-1.9	-1.9	-0.7
HbA1C	1.9	2.1	4.7	0.9	-1.1	1.2	1.8	1.0	0.8	2.2	1.8	1.9	0.0	1.7	1.6	1.3	1.4	1.8	1.6	1.8
Hypertension (Self-reported)	1.9	5.3	10.2	-1.4	-0.8	-2.0	-2.0	-1.9	-1.7	-2.9	-2.8	-2.6	-1.1	-3.2	-2.8	-2.4	-2.8	-3.1	-3.2	-1.1
Maternal smoking around birth	1.8	2.6	5.9	-2.1	-2.0	-1.4	-1.7	-1.3	-0.7	-1.6	-1.8	-0.8	-1.1	-1.8	-2.4	-1.2	-1.7	-2.1	-2.1	-1.5
Knee pain experienced in last month	1.8	2.8	5.7	1.5	0.8	0.1	2.0	0.9	1.9	1.9	2.0	1.8	1.5	1.9	1.6	2.4	2.1	1.8	1.8	1.5
Alzheimer’s Disease (including proxy)	1.7	2.5	5.0	-2.1	-1.4	1.1	-2.1	0.6	-0.5	-1.5	-2.2	-0.8	-1.0	-2.1	-2.2	-1.4	-1.7	-2.1	-2.0	-0.9
Lung FEV1/FVC ratio	1.7	8.6	19.3	1.9	2.2	1.0	3.1	2.9	3.5	3.4	3.4	2.9	2.9	3.4	2.5	4.4	3.8	3.1	3.2	1.9
Fed-up feelings	1.7	3.0	5.6	1.3	0.7	0.8	2.0	1.5	2.3	2.1	2.1	2.4	0.3	2.0	1.7	2.0	1.8	1.9	1.9	2.2
Had menopause	1.7	2.1	4.9	2.2	1.0	0.7	1.7	0.5	1.6	1.1	1.8	0.1	1.9	1.8	1.9	1.3	1.7	1.8	1.7	0.7
BMI	1.6	9.1	20.0	3.7	0.4	1.1	4.2	1.2	2.3	3.0	3.5	2.7	3.0	3.0	3.5	4.5	4.1	3.4	3.5	2.2
Medication: Co-codamol	1.6	1.9	4.8	0.4	0.2	-1.6	1.7	0.7	1.8	1.8	1.5	1.8	0.8	1.3	0.9	1.8	1.5	1.2	1.1	2.2
High blood pressure	1.6	4.4	8.5	-1.4	-0.8	-1.9	-2.0	-1.5	-1.1	-2.6	-2.6	-2.4	-1.1	-2.9	-2.6	-2.3	-2.6	-2.9	-2.9	-0.8
Exposure to tobacco smoke outside home	1.6	2.2	5.6	1.5	1.4	2.4	1.5	2.3	1.8	1.2	1.3	0.2	1.9	1.1	1.5	1.6	1.6	1.4	1.4	-0.4
Comparative body size at age 10	1.6	4.3	8.5	2.5	1.9	1.3	2.3	1.3	0.2	1.8	2.6	0.7	2.5	2.7	2.9	2.0	2.6	2.8	2.8	0.4
Medication for pain relief, constipation, heartburn	1.6	2.7	7.2	-1.0	-0.4	0.7	-2.3	-1.1	-2.7	-2.5	-2.0	-2.5	-0.0	-1.8	-1.1	-2.0	-1.5	-1.6	-1.3	-1.6
Miserableness	1.6	2.8	6.3	1.4	0.8	0.5	2.5	1.0	1.4	2.0	2.3	2.0	0.8	2.2	1.5	2.3	1.9	1.8	1.7	1.9
Crohns Disease (2017)	1.5	3.2	6.2	-1.4	-0.8	-2.5	-2.0	-1.8	-1.1	-1.8	-2.2	-1.8	-1.0	-2.2	-2.2	-1.7	-2.0	-2.3	-2.3	-0.8
Lupus	1.5	2.2	6.9	0.1	-1.1	-1.1	2.3	0.3	1.9	1.6	1.8	2.6	-0.0	1.5	1.2	2.0	1.6	1.5	1.3	1.4
Stomach or abdominal pain in last month	1.5	1.9	5.6	0.9	0.5	-1.1	2.0	0.6	2.0	1.5	1.4	1.9	1.0	1.1	1.1	2.4	1.7	1.2	1.3	0.6
Hip circumference	1.5	6.5	10.9	3.2	2.0	2.4	3.3	1.3	1.4	2.5	3.0	1.6	2.8	2.8	3.0	3.3	3.3	2.9	2.9	1.1
Pulse wave Arterial Stiffness index	1.5	1.8	4.9	2.2	-1.1	0.0	1.5	-1.1	0.1	1.1	1.7	-0.0	1.7	1.7	1.8	0.7	1.5	1.8	1.5	1.0
Arm fat-free mass (right)	1.5	7.6	11.8	3.4	1.9	3.3	3.2	1.4	1.2	2.8	3.4	1.4	2.6	3.4	3.4	2.9	3.3	3.4	3.3	1.7
Pain type(s) experienced in last month: Hip pain	1.5	1.9	4.4	0.8	1.0	1.0	1.7	2.1	0.7	1.7	2.0	0.7	0.5	2.0	0.9	1.1	1.3	1.5	1.1	2.0
Bipolar Disorder or Schizophrenia	1.4	3.4	10.8	-0.7	-1.9	-3.3	-1.1	-3.0	-1.7	-2.2	-1.6	-1.6	-0.9	-1.9	-2.0	-1.4	-1.8	-2.1	-2.3	0.0
Ovarian Cancer	1.4	1.8	9.3	1.5	1.2	0.5	-0.5	-0.5	-1.9	-1.8	-0.7	-3.0	2.0	-0.8	-0.2	-0.7	-0.3	-0.8	-0.8	-2.3
Crohns Disease (2012)	1.4	2.2	3.9	-1.6	-0.5	-1.6	-1.8	-0.8	-0.6	-1.1	-1.8	-0.8	-2.0	-1.6	-1.9	-1.9	-1.9	-1.8	-1.9	0.7
Schizophrenia (2014)	1.4	3.0	13.5	-1.5	-1.5	-3.7	-1.1	-3.0	-1.6	-1.6	-1.3	-1.0	-1.3	-1.4	-1.8	-1.4	-1.6	-1.7	-1.9	-0.2
Trunk fat percentage	1.4	5.7	11.4	-0.3	-0.4	-2.0	-2.1	-3.1	-3.0	-3.3	-2.8	-3.4	0.0	-3.1	-2.4	-2.1	-2.3	-2.9	-2.9	-1.8
Number of incorrect matches in round	1.4	2.3	4.8	1.5	-0.3	0.5	1.9	0.8	1.9	2.0	1.7	1.6	1.3	1.5	1.3	1.9	1.8	1.5	1.4	2.2
Hearing difficulty/problems with background noise	1.4	2.2	4.9	-0.5	-0.9	-0.5	-1.4	-0.3	-0.9	-1.8	-1.8	-1.5	-1.7	-1.9	-1.8	-2.2	-2.2	-1.9	-2.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	6.7	-0.5	-0.1	0.0	1.1	1.3	1.8	2.5	1.5	2.6	-1.0	1.7	0.3	1.2	0.9	1.2	1.0	1.5
Length of working week for main job	1.4	1.5	4.1	1.5	0.0	-0.1	2.0	-0.5	-0.5	0.7	1.6	0.8	1.4	1.3	1.6	1.8	1.6	1.5	1.4	0.8
Medication: Paracetamol	1.4	2.3	6.5	0.9	0.7	-0.2	1.7	1.6	2.5	2.5	1.6	2.3	0.6	1.5	0.7	2.1	1.5	1.2	1.1	1.1
Medication: Amlodipine	1.4	2.0	3.7	-1.3	-1.1	-0.4	-1.5	-0.8	-1.0	-1.5	-1.8	-1.0	-1.5	-1.9	-1.7	-1.9	-1.9	-1.8	-1.8	0.1
Risk taking	1.4	2.0	6.1	0.8	0.1	0.7	2.0	0.6	1.6	1.4	1.5	1.4	1.4	1.2	1.4	2.5	2.0	1.5	1.6	-1.0
High blood pressure (mother)	1.3	1.8	6.2	-2.0	-0.3	0.6	-1.7	1.0	-0.4	-0.7	-1.6	0.1	-2.5	-1.5	-1.4	-1.8	-1.8	-1.4	-1.3	0.0
Mouth/teeth dental problems	1.3	1.9	5.7	-2.3	-1.1	-1.2	-2.1	-0.6	-0.4	-0.9	-1.5	-0.3	-2.4	-1.2	-1.4	-2.0	-1.8	-1.2	-1.1	0.1
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	5.6	1.3	0.4	-0.1	2.1	1.1	2.0	1.8	1.9	1.6	1.4	1.6	1.0	2.4	1.8	1.4	1.3	0.2
Pulse wave reflection index	1.3	1.6	4.2	2.0	-1.2	-0.2	2.1	-0.3	1.0	1.0	1.6	0.4	1.4	1.4	1.3	1.2	1.3	1.3	1.0	1.8
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	7.1	2.1	1.6	-0.6	1.6	0.0	-0.2	0.5	1.4	-0.2	2.7	1.3	0.9	2.1	1.6	1.0	0.9	-0.0
Arm predicted mass (right)	1.3	6.8	10.8	3.2	1.7	3.2	3.0	1.3	1.1	2.7	3.3	1.3	2.4	3.3	3.2	2.7	3.1	3.3	3.1	1.7
Smoking status: Previous	1.3	1.9	3.8	-0.5	-1.1	-1.7	-1.1	-1.9	-1.5	-1.9	-1.5	-1.2	-0.8	-1.6	-1.3	-1.7	-1.6	-1.6	-1.7	0.0
Financial situation satisfaction	1.3	1.6	5.4	1.7	1.4	-0.9	1.4	-0.1	-0.0	1.1	2.0	0.3	1.5	2.3	0.9	1.1	1.4	1.5	1.1	1.1
Commuting to job workplace: Public transport	1.3	1.6	7.1	-1.6	-1.7	1.0	0.0	1.5	2.0	1.3	0.2	2.7	-1.5	0.3	0.2	0.8	0.4	0.5	0.8	1.6
Vascular/heart problems diagnosed by doctor	1.3	3.6	6.9	1.5	1.6	1.7	1.8	1.7	0.9	2.2	2.4	1.7	1.3	2.6	2.2	2.0	2.3	2.5	2.5	1.0
Hand grip strength (left)	1.2	3.3	8.5	-0.8	-0.5	-0.1	-1.6	-0.9	-2.9	-2.2	-2.0	-2.3	-0.8	-2.1	-2.0	-2.0	-2.1	-2.2	-2.4	-1.9
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.9	-0.7	-1.6	-0.7	-1.2	-0.9	-1.7	-1.6	-0.8	-1.6	-0.5	-0.5	-1.4	-1.3	-1.3	-1.1	-1.3	-1.2
Happiness	1.2	1.5	5.1	0.2	0.2	0.2	1.4	1.5	2.2	1.2	1.2	1.5	1.2	1.1	0.9	2.1	1.5	1.1	1.2	-0.1
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	6.6	0.8	2.3	2.6	0.5	2.3	1.0	1.2	1.2	0.7	0.7	1.5	1.7	0.8	1.3	1.7	1.9	-0.1
Number of full brothers	1.2	1.6	4.7	-0.5	-0.7	-2.1	-0.8	-2.2	-0.9	-1.4	-1.3	-0.8	-1.2	-1.5	-1.0	-1.3	-1.4	-1.3	-1.3	-0.7
Health satisfaction	1.2	1.5	4.5	0.6	1.3	0.4	1.1	2.1	2.1	1.1	1.1	0.9	1.4	1.1	0.9	1.7	1.4	1.0	1.1	-0.4
Illnesses of father: Heart disease	1.2	1.6	5.6	-1.9	-1.2	-0.9	-1.4	-0.9	-0.1	-1.3	-2.1	-0.2	-0.6	-2.4	-1.4	-0.5	-1.1	-1.8	-1.4	-0.8
Ever depressed for a whole week	1.2	1.5	4.3	-0.2	1.8	1.1	0.1	2.1	1.4	1.5	1.1	1.4	-0.1	1.6	1.1	0.8	1.0	1.4	1.7	0.1
Body Mass Index (BMI) (2010)	1.1	1.5	3.4	1.5	-1.0	1.1	1.2	0.1	0.4	1.0	1.3	0.7	1.2	1.3	1.8	1.4	1.5	1.6	1.8	0.3
Triglycerides	1.1	1.7	5.5	-2.4	-0.1	-0.8	-1.6	-0.3	-0.1	-1.5	-1.7	-0.9	-0.3	-1.6	-1.8	-0.5	-1.1	-1.6	-1.4	-2.1
Hand grip strength (right)	1.1	3.1	9.3	-0.5	0.2	-0.2	-1.6	-1.5	-3.0	-2.0	-2.0	-2.5	-0.3	-2.2	-1.6	-1.9	-1.9	-2.1	-2.1	-1.7
Current tobacco smoking	1.1	1.8	4.4	1.3	0.7	-1.0	1.5	-0.0	1.1	1.3	1.5	0.9	2.0	1.4	1.4	2.1	2.0	1.5	1.6	0.0
Alcohol usually taken with meals	1.1	1.8	8.2	-1.0	-1.3	1.0	0.8	1.6	1.8	1.5	0.5	2.7	-1.7	0.4	0.3	0.8	0.3	0.5	0.5	2.9
Medication: Simvastatin	1.1	1.5	5.6	-0.6	-2.4	-1.7	-0.4	-2.0	-0.7	-1.5	-1.3	-0.4	-1.1	-1.7	-0.7	-1.0	-1.1	-1.2	-1.1	-1.0
Prospective memory result	1.1	1.3	2.9	0.6	0.1	0.4	1.4	0.2	1.0	1.7	1.5	1.2	0.8	1.5	1.4	1.4	1.5	1.5	1.6	0.5
Birth weight	1.1	2.3	7.0	-1.5	-0.5	0.9	-2.1	-0.4	-1.7	-1.7	-1.5	-1.8	-1.7	-1.2	-1.1	-2.6	-2.0	-1.2	-1.3	-1.3
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.3	-0.4	0.7	0.4	-1.4	-0.5	-1.8	-1.7	-1.4	-1.7	0.5	-1.3	-0.6	-1.1	-0.8	-1.1	-0.9	-1.8
Smoking status: Current	1.1	1.8	4.1	1.2	0.9	-1.2	1.3	0.0	0.8	1.3	1.6	0.8	2.0	1.6	1.4	2.0	1.9	1.5	1.6	-0.3
Medication: Paracetamol	1.1	1.7	3.7	1.4	1.2	-0.2	1.7	1.4	1.7	1.9	1.4	1.6	0.9	1.3	0.5	1.8	1.3	0.9	0.7	1.6
Arm fat-free mass (left)	1.1	5.7	9.3	3.0	2.0	3.0	2.8	1.2	0.7	2.2	2.9	1.1	2.4	2.9	3.0	2.6	2.9	2.9	2.9	1.3
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.6	-1.4	-0.9	-1.6	-1.4	-0.9	-0.4	-1.1	-1.3	-0.4	-1.5	-1.2	-1.3	-1.1	-1.4	-1.2	-1.1	0.0
Heel T-Score	1.0	8.2	27.5	-1.8	-1.3	-5.2	-2.4	-3.4	-2.5	-3.7	-2.8	-3.5	0.3	-2.9	-3.6	-1.9	-2.5	-3.4	-3.6	-1.3
Cardiovascular Disease	1.0	3.3	8.0	-0.9	-1.6	-2.5	-1.2	-2.8	-1.6	-1.9	-1.9	-1.7	-1.1	-2.3	-1.9	-1.8	-2.0	-2.2	-2.3	-1.3
Father’s age at death	1.0	1.4	2.8	0.9	0.8	0.5	1.2	0.8	1.2	1.4	1.6	1.1	1.0	1.7	1.3	1.2	1.4	1.6	1.5	0.6
Friendships satisfaction	1.0	1.3	4.4	0.5	1.9	1.6	0.6	2.1	1.6	0.5	0.6	0.1	1.5	0.6	0.9	1.2	1.1	0.7	1.0	-0.6
Asthma (self-reported)	1.0	1.9	5.7	0.0	-2.4	-2.0	-0.7	-2.2	-2.1	-1.6	-1.0	-1.7	0.1	-1.1	-1.2	-1.0	-1.1	-1.2	-1.4	-1.0
Commuting to job workplace: Cycle	1.0	1.2	2.7	-1.4	-0.9	-1.1	-0.8	-0.8	-0.7	-1.4	-1.4	-0.4	-0.8	-1.6	-1.4	-0.6	-1.1	-1.5	-1.4	-0.6
Myopia	1.0	1.5	10.3	0.8	1.6	3.2	0.0	1.9	0.8	1.3	0.9	0.5	0.2	1.4	0.9	0.4	0.8	1.2	1.2	0.1
Arm predicted mass (left)	1.0	5.0	8.2	2.9	2.0	2.9	2.6	1.1	0.5	2.0	2.6	0.9	2.3	2.6	2.8	2.4	2.7	2.7	2.7	1.4
Schizophrenia vs Biploar Disorder	0.9	1.2	3.8	-1.9	0.2	-1.8	-1.6	-1.0	-0.2	-0.3	-1.0	0.5	-1.9	-0.7	-1.4	-1.2	-1.1	-0.9	-0.9	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.9	-0.2	1.9	0.1	1.0	0.7	2.0	1.2	1.1	1.0	0.9	1.1	0.6	1.8	1.2	0.9	1.0	-0.4
Hair/balding pattern: Pattern 2	0.9	1.1	2.0	-0.6	1.1	-0.9	-1.4	-1.1	-1.2	-1.2	-1.3	-1.0	-0.3	-1.2	-1.3	-1.1	-1.2	-1.3	-1.2	-0.4
Had other major operations	0.9	1.0	2.9	0.4	1.1	-1.5	1.3	0.3	1.7	1.1	1.0	1.0	0.6	0.8	0.8	1.4	1.0	0.8	0.8	1.2
Trunk fat-free mass	0.9	5.0	11.1	2.7	2.0	3.3	2.5	1.2	0.3	2.1	2.8	1.0	1.7	2.8	2.9	2.0	2.4	2.8	2.7	1.5
Asthma	0.9	1.8	5.7	0.0	-2.4	-1.9	-0.6	-2.2	-2.2	-1.4	-0.8	-1.6	0.2	-0.9	-1.1	-0.8	-1.0	-1.1	-1.3	-0.9
Depression (self-reported)	0.9	1.0	7.9	0.1	0.4	-2.8	0.0	-1.4	0.3	-1.0	-0.5	-0.8	1.2	-0.8	-0.6	0.8	0.2	-0.7	-0.6	-1.6
Medication: Lansoprazole	0.9	1.1	4.3	1.0	0.6	-0.0	1.2	1.0	2.1	1.5	1.3	0.3	0.6	1.3	0.9	0.5	0.8	1.1	0.8	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	7.9	1.0	1.8	2.2	1.8	2.8	1.8	1.7	1.7	1.7	0.5	1.6	1.9	1.5	1.6	1.8	1.8	1.1
Medication: Ventolin 100micrograms inhaler	0.9	1.1	1.9	-0.4	-1.3	0.9	-1.2	-0.2	-1.2	-1.3	-1.2	-1.1	-0.4	-1.2	-1.0	-1.1	-1.1	-1.2	-1.2	-1.4
Medication: Blood pressure	0.9	1.6	4.0	-1.0	-2.0	-1.5	-0.7	-1.2	-0.2	-1.1	-1.4	-0.5	-0.8	-1.8	-1.7	-0.5	-1.2	-1.8	-1.8	0.6
Medication: Aspirin	0.9	1.2	5.2	-0.1	-0.4	-0.6	1.4	0.3	2.2	1.2	0.8	2.3	-0.5	0.5	0.8	1.4	1.0	0.8	0.9	0.8
Irritability	0.9	1.6	8.2	-0.0	-0.0	-0.6	1.5	1.0	2.9	1.5	1.3	2.2	-0.4	1.2	0.6	1.5	1.0	1.0	1.0	0.6
Schizophrenia (2018)	0.8	1.6	13.1	-0.0	-1.2	-3.6	0.2	-2.7	-1.4	-1.0	-0.2	-1.0	0.1	-0.5	-0.7	-0.2	-0.4	-0.7	-1.0	0.8
Alzheimer’s Disease (in mother)	0.8	0.9	3.9	-1.0	0.0	1.4	-1.2	2.0	0.2	-0.6	-1.1	-0.3	-0.4	-1.1	-1.2	-0.7	-0.9	-1.2	-1.0	-0.6
Age when periods started (menarche)	0.8	1.8	4.2	0.4	0.4	-0.1	1.4	0.8	1.6	1.9	1.6	2.1	0.5	1.7	1.1	1.8	1.5	1.5	1.5	1.5
Noisy workplace	0.8	1.0	4.9	-0.6	-1.7	-0.4	0.3	-0.3	1.7	1.5	0.6	1.3	-0.9	0.7	-0.2	0.2	0.1	0.4	0.2	2.2
Mouth/teeth dental problems: Dentures	0.8	1.3	3.7	-0.5	-1.0	-0.2	-0.3	-1.1	-0.5	-1.5	-1.4	-1.1	-0.5	-1.9	-1.1	-1.1	-1.3	-1.6	-1.7	-1.3
Trunk predicted mass	0.8	4.6	10.3	2.6	1.9	3.2	2.5	1.1	0.3	2.0	2.7	0.9	1.6	2.7	2.8	1.9	2.3	2.7	2.5	1.5
Pulse rate, automated reading	0.8	2.5	5.8	2.3	1.9	-0.6	1.4	0.2	1.0	1.4	1.7	0.3	2.4	1.8	1.8	1.8	2.0	1.8	1.9	0.9
Family relationship satisfaction	0.8	1.0	6.0	-0.2	0.8	0.6	0.5	1.3	2.4	1.1	0.9	1.0	0.2	1.1	0.6	0.9	0.8	0.9	1.0	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	5.7	-1.1	-0.5	0.5	0.1	1.1	2.4	0.8	-0.3	1.5	-1.4	-0.4	-0.7	0.2	-0.4	-0.4	-0.5	1.9
Handedness (chirality/laterality): Left-handed	0.8	1.0	4.1	-1.5	-2.0	-0.2	-0.6	-0.5	0.3	-0.4	-0.8	0.5	-2.0	-0.9	-0.9	-1.1	-1.1	-0.8	-0.9	-0.8
Loneliness, isolation	0.8	1.1	7.4	-0.4	0.4	0.4	0.5	1.9	2.7	0.9	0.6	1.6	-0.8	0.7	0.3	0.6	0.4	0.6	0.6	0.9
Qualifications: nursing, teaching	0.8	1.2	2.6	1.1	0.8	1.4	0.6	1.0	-0.8	0.6	1.0	-0.2	1.6	1.1	1.4	1.2	1.5	1.4	1.6	-0.4
Medication: Aspirin	0.8	1.1	5.4	-0.2	-0.5	-0.9	1.3	0.0	1.9	1.0	0.8	2.3	-0.7	0.5	0.8	1.3	0.9	0.8	0.9	0.9
Fractured/broken bones in last 5 years	0.8	1.0	5.1	1.5	2.3	0.2	0.6	0.1	0.0	0.4	0.9	-0.7	2.1	1.0	0.8	0.8	0.9	0.7	0.7	0.4
Taking other prescription medications	0.7	1.1	7.2	-0.7	-1.4	-2.7	-0.3	-1.3	0.2	-0.5	-0.7	0.1	-1.1	-0.8	-1.2	-0.6	-1.0	-1.0	-1.2	0.5
Chronic bronchitis/emphysema (father)	0.7	0.8	1.7	1.3	-0.8	-0.3	0.9	-0.2	-1.1	0.6	1.1	0.0	0.6	1.3	1.3	0.1	0.8	1.2	1.0	1.1
Trunk fat mass	0.7	3.0	8.0	0.4	-0.0	-1.0	-1.3	-2.6	-2.7	-2.5	-1.9	-2.8	0.5	-2.1	-1.4	-1.5	-1.5	-1.9	-1.9	-1.3
Past tobacco smoking	0.7	1.2	3.7	0.5	1.1	1.9	0.9	1.8	1.1	1.3	1.0	0.8	0.6	1.0	1.0	1.2	1.2	1.1	1.2	0.1
Lung cancer (father)	0.7	0.8	3.7	0.7	-0.1	1.9	0.7	1.2	0.3	0.5	1.0	0.4	-0.5	1.1	1.3	-0.3	0.4	1.2	1.1	0.9
Exposure to tobacco smoke at home	0.7	0.8	2.7	1.3	1.5	-0.1	0.7	0.1	0.5	0.4	0.7	-0.5	1.6	0.7	0.7	0.9	1.0	0.8	0.8	-1.3
Body fat percentage	0.7	2.6	6.0	0.2	-0.2	-1.9	-1.1	-2.5	-2.1	-2.2	-1.8	-2.4	0.6	-2.0	-1.5	-1.0	-1.2	-1.9	-1.9	-1.3
Number of children fathered	0.7	0.8	2.3	0.5	-0.7	1.0	1.5	-0.3	0.9	0.9	1.0	1.5	0.0	0.7	1.0	1.2	1.1	1.0	1.0	-0.3
Leg pain on walking	0.7	0.9	3.8	-0.0	-0.5	1.5	0.9	0.6	1.9	0.9	0.8	1.2	-0.1	0.7	0.9	0.8	0.7	0.8	0.9	1.1
Illnesses of siblings: Diabetes	0.7	0.9	2.4	1.6	0.7	0.6	1.2	0.3	0.2	1.3	1.4	-0.3	0.7	1.5	0.8	0.2	0.6	1.1	0.7	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.8	-0.9	0.7	0.5	-1.6	-0.3	-1.1	-1.2	-1.5	-1.4	-0.8	-1.4	-1.5	-1.7	-1.6	-1.6	-1.6	-1.1
Whole body fat-free mass	0.7	4.1	9.6	2.8	1.8	3.1	2.4	0.9	0.1	1.7	2.4	0.6	1.9	2.3	2.6	1.8	2.2	2.4	2.3	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	3.8	0.5	1.9	-0.8	-0.1	-0.5	-1.3	-0.2	0.5	-1.1	1.7	0.8	-0.1	0.5	0.5	0.3	0.2	-0.7
Back pain experienced in last month	0.7	1.0	3.2	0.7	0.4	0.3	1.2	0.4	1.8	1.2	1.1	0.8	1.0	1.1	0.7	1.4	1.2	1.0	0.9	1.1
Whole body water mass	0.7	4.2	10.2	2.9	1.8	3.2	2.4	1.0	0.0	1.7	2.5	0.6	1.9	2.4	2.6	1.8	2.2	2.4	2.3	1.3
Medication: Lisinopril	0.7	0.9	2.4	-0.2	-1.3	-0.3	-1.0	-0.8	-0.5	-0.8	-0.8	-1.4	-0.3	-0.7	-0.8	-1.6	-1.2	-0.9	-1.1	-1.4
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.9	1.2	-1.7	-0.3	1.3	-0.5	0.5	0.5	1.0	0.2	1.4	0.9	1.0	1.1	1.1	0.9	0.9	0.2
Primary Biliary Cirrhosis	0.6	0.9	3.4	-0.4	-1.1	-1.0	0.9	1.3	1.7	1.1	0.7	1.8	-0.1	0.7	-0.2	1.2	0.6	0.3	0.1	0.6
Systolic blood pressure, automated reading	0.6	1.8	4.2	-0.6	0.6	-0.2	-1.8	-1.1	-0.8	-1.6	-2.0	-1.5	0.1	-2.1	-1.6	-1.1	-1.4	-1.9	-1.6	-1.4
Medication for hormone replacement therapy	0.6	0.7	6.0	-0.1	2.4	0.5	0.0	0.6	-0.5	0.3	0.8	0.1	-0.3	1.2	0.5	-0.4	0.1	0.8	0.6	1.2
Diabetes (father)	0.6	0.7	2.9	-1.7	-0.9	-1.4	-0.6	-0.7	1.5	0.6	-0.2	1.4	-1.2	-0.1	-0.1	0.2	-0.0	0.1	0.4	0.8
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.5	0.8	1.1	1.0	0.5	1.1	0.2	0.9	1.0	0.5	0.5	1.2	1.1	0.3	0.8	1.1	1.2	0.1
Medication: Ramipril	0.6	0.8	1.9	-0.6	-0.6	-1.4	-0.6	-1.4	-0.9	-0.7	-0.8	-0.4	-0.8	-0.8	-1.3	-0.8	-1.0	-1.1	-1.3	0.4
Illnesses of siblings	0.6	0.9	3.5	-1.2	-1.7	0.5	-0.1	0.1	1.3	1.0	-0.1	1.9	-1.7	-0.2	-0.2	-0.0	-0.2	-0.0	-0.0	1.3
Number of live births	0.6	0.9	4.7	0.3	0.9	0.1	-0.8	-0.3	-0.3	-1.5	-0.8	-2.2	0.5	-0.7	-0.6	-1.1	-0.7	-0.8	-1.0	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	1.5	-1.1	-0.7	-1.2	-1.2	-0.9	-0.9	-1.1	-1.1	-0.6	-0.8	-1.0	-1.2	-1.0	-1.1	-1.1	-1.0	-0.8
Hair/balding pattern: Pattern 4	0.6	1.5	3.6	1.7	-1.4	0.9	1.5	0.5	0.7	1.2	1.4	0.7	0.0	1.3	1.9	0.4	1.1	1.6	1.5	1.8
Wheeze or whistling in the chest in last year	0.6	1.0	5.6	0.7	-1.3	-2.4	0.2	-1.8	-1.2	-0.8	-0.5	-0.7	1.2	-0.7	-0.7	0.6	0.1	-0.8	-0.8	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	3.0	-0.3	-1.7	-0.3	-0.5	-0.7	-0.1	-0.6	-1.0	-0.6	-1.1	-1.2	-0.8	-1.1	-1.1	-1.0	-1.1	0.3
Long-standing illness, disability or infirmity	0.6	0.9	5.2	-0.6	-2.2	-2.3	-0.0	-1.6	0.5	-0.6	-0.6	0.0	-0.1	-0.8	-0.8	0.2	-0.3	-0.8	-0.8	-0.7
Osteoporosis (self-reported)	0.6	0.7	2.4	-1.3	0.2	-1.0	-0.9	-0.2	0.0	-0.8	-0.9	0.0	-0.4	-0.8	-1.2	-0.4	-0.8	-1.1	-0.9	-1.5
Tinnitus: Yes, now most or all of the time	0.6	0.8	1.4	-1.0	-0.4	0.0	-1.2	-0.9	-0.1	-1.0	-1.1	-0.9	-0.4	-1.0	-1.0	-1.0	-0.9	-1.0	-1.0	-1.2
Medication: Atorvastatin	0.6	0.7	4.1	0.2	-1.8	-2.0	0.2	-1.8	-0.4	-0.6	-0.3	0.2	0.1	-0.5	-0.6	0.4	-0.1	-0.7	-0.6	0.0
Basal metabolic rate	0.6	3.3	7.7	2.8	1.8	2.8	2.1	0.6	-0.2	1.3	2.1	0.2	2.0	2.0	2.3	1.6	2.0	2.1	2.0	1.0
Depressed Affect (Nagel 2018)	0.5	1.1	3.6	-0.1	0.1	-0.4	1.4	0.9	1.7	1.2	1.4	1.9	-0.4	1.3	0.6	1.3	0.8	1.0	0.8	1.3
Irritable Bowel Disease (IBD)	0.5	1.2	4.0	-1.1	-0.7	-2.0	-1.1	-1.2	0.1	-1.1	-1.3	-0.8	-0.6	-1.3	-1.3	-0.8	-1.1	-1.3	-1.3	-0.5
Breast Cancer	0.5	1.1	3.6	-0.1	0.9	1.6	1.0	1.9	1.7	0.9	0.9	1.3	0.3	0.9	0.8	1.1	1.0	0.9	0.9	0.0
Coronary Artery Disease (CAD)	0.5	0.5	1.8	0.3	1.3	1.2	0.1	0.7	1.2	1.0	0.5	0.7	-0.0	1.0	0.6	0.1	0.4	0.8	0.7	0.5
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.4	-0.4	0.1	-1.3	-0.2	-0.8	-0.4	-0.2	-0.6	-0.1	1.0	-0.9	-0.9	1.2	0.1	-0.9	-0.5	-1.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.1	-1.1	-1.4	-0.7	-0.4	-0.9	1.3	-0.1	-0.6	0.6	-1.5	-0.7	-0.4	-0.8	-0.8	-0.5	-0.5	1.2
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.9	1.0	2.0	-0.5	0.2	-0.2	0.0	0.3	0.7	-0.7	0.7	1.0	0.4	-0.1	0.4	0.6	0.5	1.4
Ever had hysterectomy (womb removed)	0.5	0.5	1.5	-1.2	-0.5	-0.4	-1.2	-0.3	0.2	-0.9	-0.9	-0.4	-0.7	-0.7	-0.6	-0.9	-0.8	-0.6	-0.4	-1.2
Vitamin and mineral supplements	0.5	0.7	4.2	-2.0	0.5	-0.3	-1.1	0.2	0.5	-0.1	-0.7	0.6	-1.0	-0.5	-0.5	-0.5	-0.5	-0.5	-0.2	-1.8
Heart attack	0.5	0.6	2.4	1.1	-1.5	-0.3	1.1	-0.6	0.3	0.3	0.8	-0.1	1.2	0.7	0.8	0.9	0.8	0.7	0.7	0.1
Time employed in main current job	0.5	0.5	2.5	0.4	-0.5	-1.3	-0.1	-1.1	-1.6	-0.7	-0.4	-0.9	0.3	-0.5	-0.3	-0.5	-0.5	-0.5	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	5.9	0.4	2.1	2.3	0.8	2.4	0.9	0.8	1.1	0.9	0.2	1.1	1.4	0.9	1.0	1.3	1.4	0.5
Shortness of breath walking on level ground	0.5	0.6	1.0	-0.4	-0.6	-0.6	-0.9	-1.0	-0.8	-0.9	-1.0	-0.9	-0.2	-1.0	-0.5	-0.9	-0.8	-0.8	-0.7	-0.7
Migraine (self-reported)	0.5	0.6	3.6	0.5	-1.1	-0.9	0.3	-0.9	0.3	0.9	0.5	1.1	-0.2	0.6	0.1	0.7	0.5	0.4	0.4	1.9
Medication: Ibuprofen	0.5	0.6	2.0	-0.2	0.6	0.1	0.6	1.2	0.8	1.4	0.9	1.3	-0.7	1.1	0.2	0.4	0.4	0.7	0.5	0.8
Chest pain or discomfort	0.5	0.7	1.8	-0.1	-1.3	-1.4	-0.3	-0.7	-0.3	-1.2	-0.9	-1.1	0.2	-1.2	-0.7	-0.4	-0.6	-1.0	-1.0	-0.4
Mood swings	0.5	0.8	2.2	0.4	-0.3	-0.7	1.5	0.4	1.4	1.2	1.3	1.5	-0.1	1.2	0.6	1.1	0.7	0.9	0.7	0.2
Ever had bowel cancer screening	0.5	0.6	3.1	-0.1	-1.8	-0.4	0.2	-1.5	0.1	0.7	0.3	1.1	-1.3	0.4	-0.1	-0.4	-0.4	0.1	0.0	1.0
Hearing aid user	0.5	0.6	1.2	-1.0	0.1	-0.8	-0.9	-0.9	0.2	-0.4	-0.8	-0.0	-0.8	-0.7	-1.1	-0.6	-0.8	-0.9	-0.9	-0.9
Medication: Blood pressure	0.5	1.0	3.0	0.1	0.9	0.3	-0.9	-0.2	-1.0	-1.5	-1.1	-1.7	0.1	-1.2	-0.7	-1.3	-1.1	-1.1	-1.1	-1.0
Diastolic blood pressure, automated reading	0.5	1.5	5.8	1.9	2.2	0.7	0.9	0.9	0.8	0.6	0.5	-0.2	2.4	0.4	1.1	1.7	1.5	0.7	1.1	0.1
Supplements: Calcium	0.5	0.5	1.5	-1.2	-1.0	-0.5	-1.1	0.1	1.1	0.0	-0.6	0.5	-1.0	-0.2	-1.2	-0.4	-0.7	-0.7	-0.7	-0.1
Heart disease (siblings)	0.5	0.6	3.2	0.7	1.8	-1.4	0.3	-0.6	-0.8	-0.8	0.2	-1.3	0.9	0.1	0.2	-0.2	0.0	0.0	-0.1	-0.1
Neuroticism (Nagel 2018)	0.4	1.0	4.4	0.2	-0.0	-0.4	1.3	1.1	2.1	1.2	1.1	1.7	-0.7	1.0	0.3	0.9	0.5	0.7	0.5	1.5
Reaction Time	0.4	0.7	2.5	-1.6	-0.0	-0.4	-1.2	-0.0	0.6	-0.3	-0.9	0.2	-1.2	-0.7	-1.1	-0.7	-0.8	-0.8	-0.7	-1.2
Ulcerative Colitis	0.4	0.5	3.2	-0.8	1.2	-0.7	-0.2	0.6	1.8	0.1	-0.2	0.7	0.0	-0.2	-0.4	0.6	0.1	-0.2	-0.1	-1.4
Blood White Count	0.4	2.9	10.3	0.3	-0.2	-3.2	1.6	-0.6	1.9	2.0	1.3	2.9	1.5	1.1	0.7	3.1	2.1	1.1	1.4	0.4
Smoking Status	0.4	0.9	4.9	0.4	-0.1	-2.2	1.1	-0.4	1.0	0.8	0.8	1.4	0.6	0.5	0.5	1.4	1.0	0.6	0.6	1.0
Hypothyroidism (self reported)	0.4	1.0	5.8	-1.2	1.1	-0.6	0.4	1.3	1.3	1.0	0.4	2.4	-1.1	0.3	0.1	0.9	0.5	0.5	0.6	1.0
Number of treatments/medications taken	0.4	0.8	4.6	-0.2	-1.6	-2.1	0.1	-0.8	0.5	-0.8	-0.5	-0.2	-0.6	-0.8	-0.8	-0.3	-0.7	-0.9	-1.0	0.8
Average weekly spirits intake	0.4	0.5	1.3	1.1	-0.3	0.5	0.8	-0.1	-0.5	0.3	0.7	-0.3	0.9	0.7	1.0	0.5	0.8	0.8	0.8	0.8
Sensitivity / hurt feelings	0.4	0.6	2.6	-1.1	-0.3	-1.3	-0.2	-0.3	1.0	-0.1	-0.6	0.8	-1.6	-0.7	-0.5	-0.3	-0.7	-0.6	-0.5	1.1
Hearing difficulty/problems: Yes	0.4	0.6	2.2	0.5	-0.3	-0.3	-0.5	0.3	-0.6	-1.1	-0.7	-1.5	-0.2	-0.7	-0.7	-1.3	-1.0	-0.8	-1.1	0.0
Leg fat-free mass (left)	0.4	2.0	7.4	2.5	1.3	2.7	1.7	0.4	-0.5	0.8	1.5	-0.2	1.5	1.2	1.8	1.1	1.4	1.4	1.4	0.9
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	3.3	0.3	1.8	0.2	0.7	0.5	0.2	1.0	0.6	0.4	0.8	0.6	0.3	0.7	0.7	0.4	0.3	0.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	2.0	-0.3	-0.8	-1.3	0.2	-0.3	0.3	-0.1	-0.4	0.5	-0.2	-0.7	-1.4	0.4	-0.4	-1.0	-1.3	0.8
Medication: Atenolol	0.4	0.6	1.8	-1.0	-0.7	0.3	-0.5	-0.4	0.4	-0.7	-1.1	0.2	-0.7	-1.4	-0.8	-0.2	-0.6	-1.0	-0.8	-1.1
Medication: Levothyroxine sodium	0.4	0.7	4.0	-1.2	-0.4	-0.6	0.4	1.1	1.0	0.4	0.3	2.0	-1.6	0.2	-0.4	0.4	-0.1	0.0	-0.0	0.7
Leg predicted mass (left)	0.4	2.2	7.5	2.6	1.4	2.7	1.7	0.5	-0.5	0.8	1.5	-0.2	1.6	1.3	1.9	1.1	1.4	1.5	1.4	0.9
Diabetes (self-reported)	0.4	0.6	3.4	-0.2	-1.6	-1.8	-0.0	-1.0	0.5	-0.6	-0.5	0.2	-0.1	-0.7	-0.9	0.1	-0.4	-0.8	-0.9	-0.8
Neuroticism score	0.4	0.8	2.7	0.0	0.0	-1.0	1.3	0.7	1.7	0.7	1.0	1.6	-1.1	0.8	-0.1	0.6	0.1	0.4	0.0	1.3
Arm fat percentage (right)	0.4	1.4	4.1	1.0	0.4	-1.2	-0.4	-1.3	-1.9	-1.8	-1.2	-2.0	1.0	-1.5	-0.8	-0.5	-0.7	-1.3	-1.3	-0.6
Alcohol intake versus 10 years previously	0.4	0.6	2.2	0.3	1.2	-0.9	-0.6	-1.1	-0.3	-0.8	-0.8	-1.5	0.6	-0.9	-0.7	-0.5	-0.5	-0.9	-0.9	-0.2
Falls in the last year	0.4	0.5	1.9	0.8	0.9	0.2	0.9	1.4	0.5	0.4	0.9	-0.1	1.2	0.9	0.0	1.0	0.7	0.5	0.2	-0.1
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.9	-0.9	-1.7	1.4	-1.1	0.5	-1.7	-1.0	-1.2	-0.2	-0.9	-1.2	-0.9	-0.4	-0.8	-1.0	-0.8	0.1
Illnesses of mother	0.4	0.5	1.1	-0.0	-0.9	-0.4	0.6	-0.5	1.0	1.1	0.7	0.9	0.5	0.7	0.2	1.0	0.8	0.5	0.4	-0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.8	0.1	-0.3	0.7	0.8	1.0	0.7	0.8	0.7	1.7	-0.3	0.6	1.1	0.9	0.9	1.0	1.2	0.5
Blood clot in the leg (DVT)	0.4	0.5	2.3	0.7	0.1	1.1	0.6	0.9	0.7	0.2	0.3	0.0	1.5	0.2	0.6	1.2	0.9	0.4	0.6	-0.5
Gout (self-reported)	0.4	0.6	1.3	0.8	0.7	-0.1	0.9	0.9	1.1	0.8	0.8	0.6	0.5	0.7	0.6	1.0	0.8	0.7	0.6	1.1
High blood pressure (siblings)	0.4	0.6	2.7	1.2	1.6	-0.1	0.3	0.2	-0.3	-0.2	0.4	-0.9	1.6	0.4	0.7	0.5	0.7	0.5	0.6	-0.8
Leg fat percentage (right)	0.4	1.3	4.1	1.4	0.6	-1.0	1.6	-0.2	0.9	0.9	1.2	0.7	1.9	1.0	0.9	2.0	1.6	1.0	1.0	0.6
Medication: Seretide 50 evohaler	0.4	0.5	0.9	-0.6	-0.7	-0.9	-0.1	-0.3	-0.7	-0.6	-0.6	-0.1	-0.9	-0.8	-0.8	-0.7	-0.9	-0.8	-1.0	0.3
Heart disease (mother)	0.4	0.5	2.5	0.9	1.4	-0.3	-0.2	-0.3	-1.0	-0.9	-0.1	-1.6	0.6	0.1	0.5	-0.8	-0.2	0.1	0.2	-0.5
Leg fat mass (right)	0.4	1.4	4.0	2.0	1.0	0.1	1.6	-0.0	0.3	0.8	1.3	0.2	2.0	1.1	1.3	1.7	1.6	1.2	1.2	0.5
Had major operations	0.4	0.5	2.8	0.3	-1.0	-0.8	0.6	0.4	0.8	0.6	0.5	1.1	-0.2	0.4	0.4	0.7	0.5	0.4	0.5	1.7
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.4	0.6	1.4	-1.4	0.2	-1.6	-0.6	-0.0	0.2	-0.7	0.5	0.2	-0.2	-0.2	-0.1	-0.1	-0.4	-0.1
Diabetes diagnosed by doctor	0.4	0.7	3.1	-0.8	-1.0	-1.8	-0.5	-0.8	0.3	-0.5	-0.7	-0.0	-0.6	-0.6	-1.2	-0.4	-0.7	-0.9	-1.0	-0.8
Mineral and other dietary supplements	0.4	0.5	2.0	-0.5	-0.6	-0.3	-0.4	-0.5	-1.4	-0.9	-0.7	-0.4	-0.4	-0.8	-0.4	-0.4	-0.6	-0.6	-0.6	-1.4
Breast cancer (self-reported)	0.4	0.4	1.7	-0.0	-0.6	-1.0	-0.1	-0.4	-0.7	-1.3	-0.5	-1.1	0.4	-0.7	-0.6	-0.3	-0.4	-0.7	-0.8	-0.3
Number of self-reported non-cancer illnesses	0.4	0.7	4.8	0.5	-1.1	-2.2	0.2	-1.4	0.1	-0.8	-0.5	-0.7	0.4	-0.8	-0.4	0.1	-0.3	-0.7	-0.7	-0.8
Average weekly champagne plus white wine intake	0.4	0.5	1.4	-0.5	0.1	1.2	-1.2	0.1	-0.8	-0.6	-1.0	-1.1	0.1	-0.9	-0.3	-0.6	-0.5	-0.6	-0.3	-1.2
Wears glasses or contact lenses	0.4	0.5	2.5	0.5	-0.7	0.5	0.4	0.2	0.9	1.0	0.5	1.0	-0.1	0.5	0.5	0.6	0.5	0.6	0.6	1.6
Ever taken oral contraceptive pill	0.4	0.4	1.6	-0.3	-1.0	-0.6	-0.8	-0.4	-1.3	-0.6	-0.7	-0.5	-0.7	-0.5	-0.5	-0.9	-0.7	-0.5	-0.6	-0.3
Ever smoked	0.4	0.6	2.6	-0.6	-1.5	-1.6	-0.6	-1.1	-0.6	-1.0	-0.7	-0.4	-0.2	-0.7	-0.7	-0.3	-0.5	-0.7	-0.7	-0.3
Unable to work because of sickness or disability	0.4	0.6	5.4	-0.3	0.2	-2.3	-0.1	-1.9	-0.2	-0.2	-0.3	-0.2	0.2	-0.4	-0.2	-0.1	-0.1	-0.3	-0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.4	1.6	-1.0	-0.2	1.1	-0.0	-0.3	0.0	0.8	-0.2	0.3	0.6	0.8	0.1	0.4	0.6	0.3	1.4
Basal cell carcinoma (self-reported)	0.4	0.5	1.3	-0.4	0.5	-0.9	-1.1	-1.1	-0.8	-0.6	-0.2	-0.9	0.0	0.2	-1.0	-0.7	-0.5	-0.5	-0.7	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.9	0.7	0.2	1.1	0.7	1.0	0.8	0.4	0.4	0.3	1.4	0.3	0.6	1.2	1.0	0.5	0.7	-0.3
Alcohol drinker status: Previous	0.4	0.4	1.4	-1.1	0.2	0.1	-0.4	0.6	-0.4	-0.7	-0.4	-0.0	-0.8	-0.4	-1.2	-0.6	-0.8	-0.8	-1.0	-0.9
Pack years of smoking	0.4	0.6	2.7	-0.6	-1.6	-1.2	-0.1	-1.4	0.6	-0.6	-0.5	0.1	0.5	-0.7	-0.5	0.5	-0.0	-0.6	-0.4	-1.6
Rheumatoid Arthritis	0.3	0.4	1.2	-0.7	0.8	-0.2	-1.0	0.1	-1.1	-0.5	-0.5	-0.2	-1.1	-0.1	-0.4	-1.1	-0.8	-0.3	-0.3	0.8
Respiratory disease	0.3	0.7	3.6	1.0	-0.7	-1.9	0.0	-1.5	-1.3	-0.6	-0.2	-0.9	1.5	-0.3	-0.2	0.5	0.2	-0.4	-0.3	-0.4
Chronotype (morning person)	0.3	0.6	2.1	-0.4	0.7	-0.5	-0.8	0.2	-0.1	-0.8	-0.9	-1.0	0.7	-1.0	-1.5	-0.1	-0.6	-1.2	-1.3	-0.4
Tanning	0.3	3.9	9.0	1.2	-0.9	1.6	2.2	1.8	2.7	3.0	2.2	2.5	-0.1	2.2	1.9	1.8	1.8	2.1	2.0	2.4
Supplements: Zinc	0.3	0.3	1.5	1.1	-1.2	0.2	0.4	-0.5	-0.1	-0.3	0.2	-0.6	1.0	0.1	0.4	0.5	0.4	0.2	0.2	-0.5
Pack years adult smoking proportion	0.3	0.4	2.8	-0.1	-1.0	-0.8	0.2	-0.8	0.8	-0.2	-0.1	0.1	1.0	-0.3	-0.1	0.9	0.4	-0.2	-0.0	-1.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.2	-0.3	-0.7	0.3	0.5	1.8	1.3	0.5	0.3	1.3	0.0	0.1	0.2	1.3	0.7	0.2	0.4	1.3
Multivitamins +/- minerals	0.3	0.3	3.1	1.3	-0.2	0.1	0.7	-0.2	-0.0	-0.2	0.2	-0.6	0.4	-0.1	0.2	0.2	0.1	0.0	-0.1	1.8
Nervous feelings	0.3	0.6	3.6	-0.3	-0.8	-1.2	-0.3	-1.9	-0.4	-0.7	-0.4	0.1	-1.1	-0.4	-0.6	-0.8	-0.8	-0.5	-0.6	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.9	0.1	1.0	0.3	0.5	0.4	1.4	1.2	1.0	0.3	0.6	1.2	-0.1	0.9	0.6	0.6	0.4	0.7
Financial difficulties in last 2 years	0.3	0.3	1.5	1.0	0.3	0.0	0.6	1.2	0.7	0.4	0.7	0.0	0.8	0.8	0.3	0.6	0.5	0.5	0.3	-0.0
Fluid intelligence score	0.3	0.6	2.3	-1.3	-1.1	0.7	-0.9	0.9	0.2	-0.5	-0.9	0.3	-1.5	-0.8	-0.2	-0.7	-0.6	-0.4	-0.1	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.8	-0.0	1.2	1.7	-0.7	0.6	0.1	0.4	0.0	-0.3	-0.2	0.4	0.6	-0.7	-0.1	0.5	0.6	0.5
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.5	-0.4	-0.3	-0.1	-0.6	-1.2	0.4	-0.8	-0.7	-0.8	-0.3	-0.7	-0.4	-0.5	-0.6	-0.6	-0.6	-0.6
Forced vital capacity (FVC), Best measure	0.3	1.0	3.7	1.0	1.5	1.8	1.0	1.9	0.4	0.8	0.9	0.5	0.0	0.8	1.3	0.2	0.6	1.0	0.9	1.0
Qualifications: College or University degree	0.3	0.9	2.9	-0.9	0.5	0.4	-1.6	0.2	-1.7	-1.0	-1.0	-1.0	-1.1	-0.6	-0.7	-1.6	-1.2	-0.6	-0.6	-0.3
Medication: Omeprazole	0.3	0.3	1.8	1.4	-0.9	-0.5	1.0	0.1	-0.3	-0.1	0.6	-0.4	0.4	0.4	0.4	0.0	0.2	0.3	0.0	0.7
Whole body fat mass	0.3	1.1	3.8	1.1	0.3	-0.5	-0.4	-1.7	-1.8	-1.4	-0.9	-1.9	1.1	-1.1	-0.5	-0.4	-0.4	-0.9	-0.9	-0.9
Supplements: Vitamin C	0.3	0.3	0.8	0.9	-0.3	-0.1	0.7	-0.0	0.8	0.6	0.5	0.8	-0.0	0.3	0.8	0.6	0.5	0.6	0.7	-0.5
Leg fat-free mass (right)	0.3	1.8	7.6	2.5	1.3	2.7	1.5	0.4	-0.8	0.5	1.3	-0.5	1.6	1.1	1.6	0.8	1.2	1.3	1.2	0.5
Arm fat percentage (left)	0.3	1.2	3.5	1.1	0.3	-1.4	-0.1	-1.4	-1.7	-1.6	-1.0	-1.9	1.2	-1.4	-0.7	-0.2	-0.4	-1.2	-1.2	-0.4
Medication for cholesterol	0.3	0.5	3.2	-1.0	-1.8	0.2	-0.1	0.2	0.8	0.3	-0.2	1.2	-0.9	-0.3	-0.3	0.5	-0.1	-0.2	-0.1	-0.4
Illnesses of father: None of the above (group 1)	0.3	0.3	1.5	-0.2	0.6	0.1	0.6	1.0	1.2	0.5	0.7	0.9	-0.8	0.7	-0.3	0.2	-0.1	0.2	-0.1	-0.1
Leg predicted mass (right)	0.3	1.8	7.8	2.5	1.2	2.8	1.5	0.4	-0.8	0.5	1.3	-0.5	1.6	1.1	1.7	0.8	1.2	1.3	1.2	0.5
High cholesterol (Self-reported)	0.3	0.5	3.1	-0.2	-1.8	-1.3	0.0	-1.4	-0.1	-0.6	-0.4	0.3	-0.5	-0.5	-0.1	-0.1	-0.2	-0.4	-0.3	-0.3
Alcohol drinker status: Never	0.3	0.3	2.2	0.2	-1.5	-0.4	0.5	-0.9	0.1	0.8	0.4	0.7	-0.3	0.3	0.3	0.1	0.2	0.4	0.3	0.4
Leg fat percentage (left)	0.3	1.0	3.6	1.3	0.5	-1.1	1.3	-0.5	0.6	0.6	1.0	0.4	1.9	0.8	0.7	1.9	1.5	0.8	0.8	0.1
Age started oral contraceptive pill	0.3	0.3	2.7	0.5	-0.8	1.6	0.2	0.9	-0.2	0.1	0.2	-0.2	0.7	0.2	0.5	0.2	0.3	0.3	0.4	-0.5
Leg fat mass (left)	0.3	1.0	4.2	1.9	1.0	0.0	1.3	-0.2	-0.0	0.4	0.9	-0.1	2.0	0.8	1.0	1.5	1.4	0.8	0.9	0.1
Depression (Nagel 2018)	0.2	0.3	2.1	-0.8	-0.5	0.4	0.2	0.7	1.4	0.4	0.3	0.7	-0.2	0.4	-0.1	0.5	0.2	0.2	0.3	-0.7
Major Depression (MDD)	0.2	0.2	0.7	0.1	-0.8	0.2	-0.0	-0.8	0.9	0.0	-0.4	0.2	-0.6	-0.6	-0.2	-0.1	-0.3	-0.3	-0.3	0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.6	3.4	-0.6	-0.8	1.8	-0.2	0.7	-0.5	-0.2	-0.1	0.6	-1.0	0.1	1.1	-0.5	0.1	0.7	1.0	-0.8
Age at First Birth	0.2	0.3	1.4	0.9	0.2	-0.1	0.6	0.1	-0.7	-0.1	0.6	-0.6	0.4	0.6	0.5	-0.1	0.1	0.4	0.2	1.2
HDL Cholesterol	0.2	0.4	1.7	-0.9	0.7	0.3	-0.7	-0.2	-0.3	-0.5	-0.6	0.1	-1.3	-0.5	-0.3	-0.8	-0.6	-0.3	-0.2	-1.0
Blood Eosinophil Count	0.2	1.9	6.1	1.3	-1.1	-2.0	1.7	-0.6	1.3	1.2	1.0	1.2	1.9	0.6	0.5	2.5	1.6	0.6	0.5	2.3
Blood Platelet Count	0.2	2.3	11.2	-0.3	0.2	-3.4	0.7	0.9	1.7	2.2	1.5	2.0	0.2	2.0	0.3	1.2	1.1	1.3	1.0	2.1
Allergy or Eczema	0.2	0.7	2.7	0.1	0.1	-0.3	0.4	1.6	1.5	0.5	0.2	0.9	0.8	-0.1	0.0	1.6	0.9	0.1	0.4	1.0
Type 2 Diabetes (T2D) (2018)	0.2	0.4	2.7	-0.2	-1.3	-1.6	-0.1	-1.1	-0.2	-0.4	-0.3	-0.0	0.0	-0.4	-0.9	0.2	-0.3	-0.7	-0.8	-0.3
Neuroticism	0.2	0.5	2.9	-0.5	-0.1	-0.5	0.6	1.0	1.7	0.3	0.3	1.1	-1.4	0.2	-0.5	-0.1	-0.5	-0.1	-0.4	0.7
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.9	-0.3	1.0	-0.7	0.2	0.3	0.6	-0.1	0.3	0.0	0.9	0.3	-0.3	1.0	0.4	0.0	0.1	-1.4
Angina	0.2	0.2	2.5	0.6	-1.6	-0.0	0.6	-0.2	-0.1	-0.2	0.1	-0.1	-0.0	-0.1	0.6	-0.1	0.1	0.2	0.3	-0.0
Diabetes (mother)	0.2	0.3	0.7	0.5	0.7	0.8	0.2	0.3	-0.1	0.3	0.6	-0.3	0.3	0.8	0.6	0.2	0.5	0.7	0.7	-0.3
Townsend deprivation index at recruitment	0.2	0.2	0.9	-0.2	-0.7	-0.5	0.3	-0.9	0.4	0.4	0.2	0.8	-0.8	0.1	0.2	-0.1	-0.2	0.2	0.1	0.9
Relative age voice broke	0.2	0.3	1.7	-0.4	-0.5	0.0	0.0	-0.2	0.6	0.8	0.1	0.4	-1.3	0.1	0.3	-0.5	-0.3	0.3	0.2	0.9
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.6	-0.0	-0.5	-0.8	0.4	-0.0	1.3	0.2	0.3	0.8	0.2	0.3	-0.1	0.9	0.4	0.1	0.1	0.1
Qualifications: CSEs or equivalent	0.2	0.3	0.9	-0.7	-1.0	0.3	-0.7	-0.9	-0.2	-0.3	-0.6	-0.3	-0.3	-0.5	-0.6	-0.5	-0.5	-0.5	-0.4	-0.8
Forced vital capacity (FVC)	0.2	0.8	5.0	0.7	1.9	2.2	0.3	1.8	-0.6	-0.1	0.4	-0.4	0.3	0.4	0.9	-0.2	0.2	0.6	0.6	0.3
Weight	0.2	1.1	5.2	2.3	1.3	0.9	1.2	-0.8	-1.1	-0.2	0.7	-1.0	1.9	0.5	1.1	0.8	1.0	0.7	0.6	0.1
Hair/balding pattern: Pattern 3	0.2	0.4	2.1	-0.1	-1.0	-1.1	-0.0	-1.4	-0.2	-0.3	-0.0	-0.1	-0.2	-0.0	-0.1	-0.1	-0.1	-0.1	-0.1	-1.4
Pulse rate	0.2	0.3	1.5	-0.3	0.4	-0.8	-1.2	-0.2	-0.9	-0.6	-0.7	-0.7	0.2	-0.4	-0.5	-0.6	-0.5	-0.4	-0.2	-0.8
Arm fat mass (right)	0.2	0.8	4.3	2.1	1.1	-0.0	0.8	-0.6	-1.2	-0.6	0.2	-1.3	1.8	-0.2	0.5	0.6	0.6	0.0	-0.0	0.0
Breastfed as a baby	0.2	0.3	0.9	0.2	-0.2	0.4	0.6	-0.0	0.1	0.8	0.6	1.0	0.0	0.6	0.7	0.6	0.6	0.7	0.7	0.5
Tense / ‘highly strung’	0.2	0.3	1.5	0.1	-0.4	-0.9	0.4	-0.0	1.2	0.2	0.2	0.6	-0.7	0.1	-0.3	0.2	-0.1	-0.1	-0.2	1.0
Peak expiratory flow (PEF)	0.2	0.5	2.0	-1.4	0.5	0.2	-0.9	0.3	-0.5	-0.6	-0.7	0.1	-1.0	-0.6	-0.8	-0.4	-0.7	-0.7	-0.6	-0.5
Loud music exposure frequency	0.2	0.2	0.6	0.4	0.7	-0.6	0.5	0.8	0.5	0.5	0.6	0.2	-0.6	0.6	-0.1	-0.2	-0.2	0.3	-0.1	0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.9	-1.4	0.6	-1.1	-0.3	0.2	0.3	0.0	-0.2	1.2	-1.2	-0.2	-0.6	-0.0	-0.4	-0.3	-0.2	0.1
Neck or shoulder pain in last month	0.2	0.3	1.5	0.3	-0.4	-0.6	-0.3	-1.2	-0.7	-0.2	-0.1	-0.7	0.8	-0.0	-0.0	0.2	0.2	-0.0	0.1	-0.7
Angina (self-reported)	0.2	0.2	2.8	0.5	-1.7	-0.1	0.5	-0.2	-0.2	-0.3	0.0	-0.1	-0.2	-0.2	0.4	-0.2	-0.1	0.0	0.1	0.1
Alcohol intake frequency.	0.2	0.5	2.4	0.7	0.4	-1.6	1.0	-0.8	-0.2	-0.1	0.4	0.2	1.2	0.0	-0.4	1.2	0.5	-0.2	-0.4	-0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.3	0.3	0.5	-0.2	-0.0	-1.1	-0.7	-0.5	-0.3	-0.6	0.5	-0.5	-0.0	0.1	-0.0	-0.3	-0.2	-0.7
Eye problems/disorders: Cataract	0.2	0.3	1.8	-0.7	-0.7	0.2	-0.1	-0.4	-0.1	-0.4	-0.5	0.7	-1.4	-0.6	0.0	-0.4	-0.5	-0.3	-0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	2.1	-0.8	-0.8	1.4	-0.4	0.8	0.2	0.1	-0.4	0.3	-0.6	-0.3	0.0	-0.2	-0.2	-0.1	0.1	-0.1
Medication: Gliclazide	0.2	0.2	0.6	-0.2	-0.8	-0.1	0.3	-0.0	0.4	0.6	0.4	0.8	0.1	0.5	0.3	0.7	0.5	0.5	0.6	-0.0
Arm fat mass (left)	0.2	0.8	4.6	2.1	0.8	0.1	1.0	-0.7	-1.0	-0.3	0.4	-1.0	1.9	0.1	0.7	0.8	0.8	0.3	0.3	0.4
Medication: Bendroflumethiazide	0.2	0.4	1.1	0.6	0.4	0.9	-0.3	-0.7	-0.5	-1.0	-0.3	-1.0	1.0	-0.3	0.1	-0.0	0.1	-0.2	-0.0	-0.9
Illnesses of father: High blood pressure	0.2	0.3	1.7	0.2	1.3	-0.5	-0.4	0.2	-0.4	0.0	-0.3	-0.8	0.4	-0.2	-0.6	-0.4	-0.4	-0.5	-0.7	-0.2
Average weekly beer plus cider intake	0.2	0.3	1.4	0.2	0.4	-0.9	-0.1	-1.0	-0.5	-0.5	-0.2	-0.7	-0.1	-0.2	-0.3	-0.7	-0.4	-0.3	-0.4	-1.2
Cholesterol lowering medication	0.2	0.3	1.2	0.7	-1.1	-0.4	0.1	-1.1	-0.1	-0.6	-0.4	-0.5	0.5	-0.6	0.4	-0.1	0.0	-0.2	0.0	-0.3
Pain experienced in last month	0.2	0.4	2.2	0.7	0.1	0.5	-0.4	0.1	-1.5	-0.8	-0.4	-1.3	0.8	-0.3	0.4	-0.4	-0.1	-0.1	-0.0	-0.7
Intelligence (Savage-Jansen 2018)	0.1	0.4	3.1	-0.8	-1.8	1.0	-0.4	0.4	-0.6	-0.5	-0.4	0.5	-0.8	-0.4	0.1	-0.3	-0.3	-0.1	0.2	-0.3
Worry (Nagel 2018)	0.1	0.2	1.1	0.1	-0.7	-0.9	0.3	-0.1	1.1	-0.3	0.0	0.3	-0.9	-0.1	-0.4	-0.3	-0.4	-0.3	-0.5	0.5
Ulcerative Colitis (UC)	0.1	0.2	1.5	-0.1	0.1	-1.2	0.4	-0.2	1.1	0.2	0.3	0.4	0.3	0.3	0.1	0.6	0.3	0.2	0.1	0.7
Relative age of first facial hair	0.1	0.2	0.8	0.1	0.5	0.1	0.3	-0.4	-0.8	0.5	0.2	0.5	-0.4	0.1	0.4	0.1	0.2	0.4	0.3	0.9
Medication: Metformin	0.1	0.1	0.8	0.4	0.0	-0.6	-0.2	-0.0	0.4	-0.1	-0.1	-0.5	0.7	0.0	-0.4	0.1	0.0	-0.2	-0.3	-0.9
Severe depression (siblings)	0.1	0.1	0.3	-0.1	0.0	-0.1	-0.4	-0.6	-0.5	-0.4	-0.4	-0.5	-0.2	-0.4	-0.1	-0.6	-0.4	-0.3	-0.2	-0.6
Average weekly fortified wine intake	0.1	0.2	0.9	-0.1	-0.1	0.5	0.4	0.7	0.9	0.1	-0.1	0.6	-0.5	-0.4	0.1	-0.0	-0.1	-0.1	-0.1	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.2	0.2	1.1	-0.3	0.2	0.5	0.5	-0.2	0.1	-0.6	0.5	0.0	0.2	0.3	0.2	0.1	0.1	0.2
Waist circumference	0.1	0.5	2.4	1.5	0.5	-0.8	0.7	-0.9	-0.6	-0.3	0.3	-0.8	1.5	0.1	0.2	0.6	0.5	0.1	-0.0	0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.6	-0.1	0.4	-0.1	0.3	0.5	0.7	0.1	0.2	0.0	0.6	0.2	0.1	0.8	0.5	0.1	0.2	-0.2
Qualifications: None of the above	0.1	0.1	0.6	0.5	0.2	-0.8	0.5	-0.1	0.6	-0.2	0.1	-0.1	0.3	-0.2	-0.4	0.1	-0.1	-0.4	-0.6	0.1
Allergy	0.1	0.3	3.4	0.4	1.8	0.2	0.5	-0.4	0.3	0.6	0.5	0.3	0.0	0.5	0.5	-0.0	0.3	0.6	0.5	-0.4
Pain all over the body in last month	0.1	0.1	1.0	-0.5	-0.4	0.3	-0.2	0.4	-0.1	-0.2	-0.2	-0.3	-0.3	-0.1	-0.1	-0.7	-0.3	-0.1	-0.2	-1.0
Worrier / anxious feelings	0.1	0.2	1.7	0.2	-0.3	-1.3	0.6	0.2	0.7	-0.2	0.2	0.6	-0.4	0.0	-0.0	0.3	0.0	-0.0	-0.1	0.8
Birth weight of first child	0.1	0.2	1.0	-0.4	-0.9	0.6	-0.5	0.4	-0.5	-0.6	-0.4	-0.4	-0.1	-0.4	-0.1	-0.2	-0.2	-0.2	-0.1	-1.0
Ever highly irritable/argumentative for 2 days	0.1	0.1	1.3	-0.1	0.5	-0.5	0.2	-0.1	1.1	0.0	0.2	0.1	-0.0	0.2	0.6	0.2	0.3	0.4	0.4	0.1
Headache pain in last month	0.1	0.1	0.4	-0.1	-0.4	0.3	-0.3	-0.6	0.2	0.3	0.1	0.3	0.4	0.2	-0.5	0.7	0.3	-0.0	0.0	-0.2
Worry too long after embarrassment	0.1	0.2	1.4	-0.1	0.5	-0.0	0.4	1.2	0.8	0.2	0.2	0.2	-0.7	0.1	-0.5	0.0	-0.4	-0.2	-0.5	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.9	0.4	0.3	-1.0	0.5	-0.9	0.0	0.1	0.2	0.2	0.4	0.1	0.3	0.6	0.3	0.2	0.3	-0.5
Age at first live birth	0.1	0.2	1.9	-0.1	-0.3	-0.4	0.1	-0.3	-1.4	0.1	0.2	0.1	-0.7	0.3	0.1	-0.4	-0.2	0.1	-0.1	0.7
Medication: Allopurinol	0.1	0.1	0.6	-0.0	0.5	-0.8	-0.1	0.0	0.6	0.4	0.1	0.4	0.0	0.1	-0.3	0.4	0.1	-0.0	-0.0	-0.0
Mean time to correctly identify matches	0.1	0.1	0.7	-0.5	-0.8	0.1	-0.1	-0.3	0.8	0.1	-0.1	0.7	-0.5	-0.1	-0.0	0.1	0.0	0.0	0.1	-0.1
Suffer from ‘nerves’	0.1	0.1	0.8	0.2	-0.2	0.2	0.1	0.4	0.9	0.3	0.1	0.6	-0.5	0.1	-0.1	0.2	-0.0	0.0	0.0	0.5
Overall health rating	0.1	0.3	2.1	-0.1	0.4	-1.5	0.5	-0.3	1.1	0.4	0.1	0.6	0.2	-0.1	-0.2	0.7	0.3	-0.1	-0.0	-0.6
Age at last live birth	0.1	0.2	0.9	-0.1	0.6	-0.6	-0.2	-0.2	-0.9	-0.1	0.0	-0.3	-0.4	0.2	-0.1	-0.6	-0.3	-0.1	-0.2	0.6
Average weekly red wine intake	0.1	0.2	0.5	-0.0	0.6	-0.1	-0.6	0.5	-0.1	-0.5	-0.7	-0.6	0.2	-0.7	-0.3	-0.4	-0.4	-0.6	-0.5	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	1.2	0.1	-0.3	0.6	-0.0	-0.3	1.1	0.2	0.1	-0.0	0.1	0.2	0.2	0.2	0.2	0.2	0.3	0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.4	2.2	0.9	-0.4	-1.5	0.9	-0.4	-0.4	-0.2	0.3	0.2	1.0	-0.1	0.4	0.9	0.6	0.1	0.1	-0.5
Hair Pigment	0.0	0.7	3.3	0.7	1.1	1.8	0.6	1.8	0.8	0.8	0.9	0.2	0.3	1.0	0.4	0.3	0.5	0.7	0.5	0.1

Hub : Genes

OGN

Models

Trait associations