TWAS
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Traits
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Traits
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Impedance of arm (right)
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chr15:30,930,500-31,932,865
Best TWAS P=3.79e-09 · Best GWAS P=1.41e-08 conditioned to 0.0585
31M
31.2M
31.4M
31.6M
31.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Adipose Subcutaneous
FAN1
0.10
0.04
lasso
6
0.08
4.4e-07
-5.0
-5.9
3.8e-09
-0.75
0.05
0.94
TRUE
1
CommonMind
Brain Pre-frontal Cortex
FAN1
0.09
0.12
lasso
4
0.12
3.9e-14
-5.1
-5.7
1.1e-08
-0.71
0.04
0.96
FALSE
5
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
MTMR15
0.05
0.01
blup
56
0.02
3.5e-03
5.0
-5.5
4.9e-08
-0.82
0.02
0.85
FALSE
3
GTEx
Lung
FAN1
0.04
0.03
enet
4
0.05
9.1e-05
5.7
-5.2
2.1e-07
-0.82
0.01
0.98
FALSE
4
GTEx
Testis
RP11-540B6.6
0.19
0.16
lasso
7
0.16
1.4e-07
5.0
5.2
2.5e-07
0.74
0.06
0.94
FALSE