Best TWAS P=3.79e-09 · Best GWAS P=1.41e-08 conditioned to 0.0585
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAN1 | 0.09 | 0.12 | lasso | 4 | 0.12 | 3.9e-14 | -5.1 | -5.7 | 1.1e-08 | -0.71 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | FAN1 | 0.10 | 0.04 | lasso | 6 | 0.08 | 4.4e-07 | -5.0 | -5.9 | 3.8e-09 | -0.75 | 0.05 | 0.94 | TRUE |
| 3 | GTEx | Lung | FAN1 | 0.04 | 0.03 | enet | 4 | 0.05 | 9.1e-05 | 5.7 | -5.2 | 2.1e-07 | -0.82 | 0.01 | 0.98 | FALSE |
| 4 | GTEx | Testis | RP11-540B6.6 | 0.19 | 0.16 | lasso | 7 | 0.16 | 1.4e-07 | 5.0 | 5.2 | 2.5e-07 | 0.74 | 0.06 | 0.94 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MTMR15 | 0.05 | 0.01 | blup | 56 | 0.02 | 3.5e-03 | 5.0 | -5.5 | 4.9e-08 | -0.82 | 0.02 | 0.85 | FALSE |