Hub : Genes

RP11-540B6.6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1060	0.0460	1.9e-03	0.052	NA	0.011	NA	0.053	1.1e-03	NA	8.2e-02	NA	9.7e-04
2	GTEx	Brain Cerebellar Hemisphere	0.2950	0.1120	9.8e-04	0.039	NA	0.020	NA	0.050	3.7e-02	NA	9.8e-02	NA	2.0e-02
3	GTEx	Brain Cerebellum	0.3150	0.0780	1.1e-06	0.322	NA	0.304	NA	0.285	3.1e-10	NA	1.1e-09	NA	4.7e-09
4	GTEx	Brain Frontal Cortex BA9	0.2971	0.1185	1.4e-03	0.061	NA	0.092	NA	0.036	1.1e-02	NA	2.0e-03	NA	3.9e-02
5	GTEx	Brain Nucleus accumbens basal ganglia	0.1990	0.0960	7.4e-03	0.081	NA	-0.011	NA	-0.003	3.5e-03	NA	9.9e-01	NA	4.1e-01
6	GTEx	Cells Transformed fibroblasts	0.0850	0.0290	5.8e-05	0.067	NA	0.043	NA	0.063	9.6e-06	NA	3.5e-04	NA	1.7e-05
7	GTEx	Colon Transverse	0.1370	0.0490	1.9e-04	0.130	NA	0.107	NA	0.115	9.6e-07	NA	8.7e-06	NA	4.1e-06
8	GTEx	Esophagus Gastroesophageal Junction	0.1810	0.0680	1.3e-03	-0.005	NA	0.015	NA	-0.007	5.6e-01	NA	9.3e-02	NA	7.1e-01
9	GTEx	Esophagus Mucosa	0.0960	0.0380	1.0e-03	0.045	NA	0.011	NA	0.033	5.5e-04	NA	6.0e-02	NA	2.9e-03
10	GTEx	Heart Left Ventricle	0.2419	0.0662	6.8e-06	0.083	NA	0.094	NA	0.102	3.5e-05	NA	1.1e-05	NA	4.7e-06
11	GTEx	Liver	0.2210	0.0710	8.6e-05	0.238	NA	0.197	NA	0.200	2.8e-07	NA	3.5e-06	NA	2.9e-06
12	GTEx	Muscle Skeletal	0.0631	0.0224	1.1e-04	0.039	NA	0.060	NA	0.048	1.1e-04	NA	1.5e-06	NA	1.5e-05
13	GTEx	Nerve Tibial	0.1142	0.0393	6.6e-05	0.057	NA	0.038	NA	0.007	7.4e-05	NA	1.1e-03	NA	1.0e-01
14	GTEx	Testis	0.1920	0.0560	2.5e-06	0.156	NA	0.098	NA	0.160	2.0e-07	NA	4.1e-05	NA	1.4e-07
15	GTEx	Thyroid	0.0660	0.0290	2.0e-03	0.078	NA	0.062	NA	0.081	1.5e-06	NA	1.6e-05	NA	9.0e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.3	0.5	1.6	-0.0	-1.0	-0.3	1.3	0.9	-0.8	-0.4	0.5	-0.0	-1.1	-0.3	-0.7	-0.5	-0.5	-0.5
Bipolar Disorder or Schizophrenia	0.7	1.6	5.8	-1.1	-1.4	-0.9	-0.2	0.9	-1.4	-1.3	-0.1	-1.3	-2.4	-1.3	-1.2	-1.3	-1.4	-1.3
Depressed Affect (Nagel 2018)	0.3	0.7	2.7	-1.7	-1.3	-0.6	-1.2	0.9	-0.7	-0.7	-0.5	0.3	0.8	-0.6	-0.1	-0.6	-0.4	-0.7
Depression (Nagel 2018)	1.1	1.6	5.8	-2.4	-1.4	-0.1	-1.4	2.0	-1.2	-1.1	-1.4	0.3	-0.5	-1.2	-0.0	-1.2	-0.8	-1.2
Intelligence (Savage-Jansen 2018)	4.6	14.1	20.0	3.7	3.6	2.4	2.9	-3.7	4.3	4.4	2.6	3.5	3.9	4.4	3.1	4.5	4.1	4.4
Neuroticism (Nagel 2018)	0.1	0.3	1.1	-0.8	-0.6	0.4	-0.4	0.4	0.1	0.0	0.1	1.0	1.1	0.2	0.5	0.1	0.5	0.1
Schizophrenia (2018)	0.8	1.7	5.0	-1.4	-1.1	-0.9	-1.1	0.4	-1.2	-1.4	-0.5	-1.6	-2.2	-1.4	-1.0	-1.3	-1.4	-1.4
Schizophrenia vs Biploar Disorder	0.5	0.6	2.6	-0.4	0.8	0.1	-1.1	-0.3	-0.2	-0.6	1.6	-1.6	0.1	-0.8	-0.0	-0.6	-1.0	-0.6
Worry (Nagel 2018)	0.6	1.2	2.6	1.1	0.3	1.5	-0.4	-0.2	0.9	1.3	0.5	1.0	1.6	1.4	0.8	1.1	1.4	1.3
Alzheimer’s Disease (in mother)	0.5	0.5	2.5	-0.4	-1.6	-1.3	0.3	0.6	-0.2	0.1	-0.5	1.3	0.1	0.2	-0.8	0.0	0.4	0.1
Alzheimer’s Disease (in father)	0.7	0.8	1.8	1.2	0.7	0.2	0.9	-1.3	1.0	0.7	1.0	0.8	0.8	0.9	-0.3	0.9	0.9	0.9
Alzheimer’s Disease (including proxy)	0.6	0.8	3.9	-0.0	-0.8	-0.9	2.0	-0.5	0.6	0.6	0.4	1.6	0.7	0.8	-0.6	0.8	1.1	0.7
Crohns Disease (2017)	0.1	0.1	0.9	-0.2	-0.5	0.0	-0.9	0.0	-0.1	0.2	0.7	0.0	-0.3	0.2	0.3	0.1	0.1	0.1
Irritable Bowel Disease (IBD)	0.0	0.1	0.4	0.1	-0.6	-0.1	-0.6	0.1	-0.5	-0.0	0.2	-0.2	-0.4	-0.1	-0.2	-0.2	-0.2	-0.2
Ulcerative Colitis (UC)	0.3	0.5	1.2	-0.2	-1.0	-0.6	-0.2	0.6	-1.1	-0.6	-0.5	-0.6	-0.8	-0.7	-0.5	-0.8	-0.7	-0.8
Major Depression (MDD)	1.1	1.4	4.0	1.1	1.3	2.0	0.1	-0.4	1.0	1.3	1.0	1.2	1.4	1.3	0.8	1.1	1.2	1.2
Reaction Time	0.3	0.6	2.1	-0.1	-0.4	0.2	1.2	-0.1	0.5	0.8	-1.5	0.7	0.2	0.8	0.8	0.7	0.8	0.9
Verbal and Numeric Reasoning (VNR)	2.5	6.0	9.1	1.3	2.3	1.1	2.0	-2.7	3.0	2.7	1.0	3.0	2.5	2.8	2.4	3.0	3.0	2.8
Breast Cancer	0.4	1.0	4.8	-1.1	-1.6	-2.2	0.8	1.1	-0.9	-0.9	-0.5	-0.1	0.1	-0.9	-0.5	-0.9	-0.6	-0.7
Ovarian Cancer	0.3	0.4	2.5	0.5	-0.2	0.1	0.4	0.1	-0.4	-0.5	0.3	-1.1	-1.6	-0.6	-0.6	-0.6	-0.9	-0.6
Prostate Cancer	2.3	3.3	6.2	-2.5	-1.7	-1.5	-1.1	1.9	-2.0	-2.2	-0.7	-0.4	-1.8	-2.2	-2.1	-2.0	-1.7	-2.1
Age at First Birth	1.7	2.4	5.0	-1.5	-1.4	-1.7	-1.0	1.0	-1.6	-1.5	-2.1	-1.0	-2.2	-1.5	-1.7	-1.3	-1.6	-1.4
Bipolar Disorder (2011)	2.0	1.9	3.7	-1.0	-1.6	-1.0	-1.5	1.9	-1.7	-1.3	-1.0	-0.9	-1.3	-1.3	-1.5	-1.6	-1.4	-1.3
Body Mass Index (BMI) (2010)	0.4	0.5	2.9	-0.2	0.5	0.7	-1.7	-0.4	-0.2	-0.4	0.4	-1.1	-1.1	-0.5	1.0	-0.3	-0.4	-0.3
Coronary Artery Disease (CAD)	0.6	0.7	3.2	-0.9	-0.9	-0.4	-1.8	0.5	-0.7	-0.8	0.3	-0.7	-1.2	-0.9	-0.1	-0.7	-0.1	-0.4
Crohns Disease (2012)	0.1	0.2	1.3	-0.6	-0.3	0.3	-0.3	0.1	-0.2	-0.1	-0.8	0.1	-1.1	-0.1	0.4	0.0	0.0	-0.1
Mean Putamen Volume	0.7	0.8	4.3	-1.0	-0.9	-0.1	-2.1	1.1	-0.8	-0.5	-1.8	0.7	0.2	-0.4	-0.4	-0.5	0.0	-0.4
Fasting Glucose	1.1	1.3	2.2	1.4	0.8	0.6	-0.2	-1.2	1.3	1.2	0.8	1.5	1.4	1.3	1.1	1.3	1.2	1.1
HbA1C	0.3	0.3	1.6	0.2	-0.2	-0.4	-1.3	-0.1	-0.3	-0.3	0.7	-0.6	-0.5	-0.3	0.7	-0.3	-0.3	-0.3
HDL Cholesterol	0.3	0.5	2.6	-0.6	-0.5	0.2	0.7	0.9	-0.6	-0.7	1.6	0.1	1.0	-0.7	-0.4	-0.6	-0.3	-0.4
LDL Cholesterol	1.2	2.0	5.4	2.0	2.1	2.3	-1.2	-1.4	1.1	1.5	0.7	0.3	0.4	1.4	1.5	1.1	0.9	1.2
Lupus	0.1	0.1	0.3	-0.5	0.2	-0.4	-0.3	-0.4	0.4	0.4	-0.1	0.0	0.6	0.3	0.3	0.4	0.0	0.0
Neuroticism (2016)	0.5	0.7	3.4	-1.8	-1.1	0.6	-0.7	1.1	-0.5	-0.7	-1.2	0.2	-0.1	-0.6	0.8	-0.6	-0.2	-0.7
Primary Biliary Cirrhosis	0.2	0.3	1.4	0.1	-0.7	0.0	0.2	0.2	0.0	0.0	-1.1	1.2	-0.9	0.2	0.5	0.0	0.7	0.2
Rheumatoid Arthritis	0.7	1.0	3.2	0.3	1.6	1.3	0.4	-1.1	1.0	0.6	1.8	0.6	1.2	0.5	0.8	0.8	0.6	0.6
Schizophrenia (2014)	0.7	1.5	4.6	-1.4	-1.1	-0.8	-0.4	0.5	-1.2	-1.4	-0.0	-1.1	-2.1	-1.3	-1.5	-1.3	-1.3	-1.4
Triglycerides	0.2	0.3	0.9	0.5	0.9	0.8	-0.5	-0.8	0.6	0.4	0.6	-0.2	0.1	0.4	0.5	0.3	0.2	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.5	3.3	-0.5	-0.4	-0.3	-0.9	0.0	-0.3	-0.5	-1.4	-0.4	-1.8	-0.4	-0.0	-0.4	-0.6	-0.8
Ulcerative Colitis	1.3	1.8	4.4	-0.8	-1.3	-0.4	-0.9	0.8	-1.4	-1.5	-1.7	-0.7	-2.1	-1.5	-2.1	-1.4	-1.1	-1.3
Blood Eosinophil Count	0.0	0.2	1.4	0.2	0.4	0.7	-0.4	-0.1	-0.1	-0.1	-0.4	-1.2	-0.2	-0.2	-0.0	-0.2	-0.4	-0.3
Blood Platelet Count	0.1	0.7	2.4	0.1	-0.4	-0.3	0.2	-0.6	1.0	0.8	-1.1	1.6	1.1	0.9	-0.0	1.0	1.2	0.9
Blood Red Count	0.5	4.6	11.6	2.8	1.3	0.9	3.4	-1.6	1.9	2.0	2.4	0.7	3.2	2.0	2.5	1.9	1.5	1.9
Blood White Count	0.1	0.7	3.5	0.7	1.7	1.9	-0.8	-0.9	0.2	0.6	0.2	-0.9	0.3	0.5	0.3	0.4	0.1	0.4
Heel T-Score	0.1	0.7	4.2	-0.5	-0.9	-2.0	0.9	-0.2	0.2	-0.2	0.9	1.5	0.0	-0.1	-0.9	0.1	0.5	-0.1
BMI	1.3	7.4	10.6	-2.1	-2.1	-1.9	-3.3	2.8	-3.2	-3.1	-0.0	-3.2	-2.2	-3.2	-2.2	-3.2	-3.2	-3.0
Height	0.1	1.3	8.1	-1.8	-1.8	-1.1	2.9	0.6	-0.5	-0.8	-0.8	0.2	-0.8	-0.6	0.5	-0.5	-0.4	-0.8
Waist Hip Ratio (WHR)	0.2	1.0	5.2	-0.1	-0.3	-0.9	2.3	-0.8	0.3	0.1	-2.3	-0.4	-1.1	-0.0	1.5	0.2	0.3	0.2
Systolic Blood Pressure	0.6	3.2	6.3	-1.8	-1.9	-2.0	1.7	1.6	-2.0	-1.8	-1.8	-0.5	-2.5	-1.7	-1.7	-1.7	-1.5	-1.9
Smoking Status	0.7	1.6	3.5	0.7	1.1	1.9	0.9	-1.1	1.4	1.4	0.3	1.1	0.6	1.4	1.8	1.4	1.6	1.5
Allergy or Eczema	0.6	1.5	2.8	0.8	0.7	1.0	-0.0	-1.2	1.5	1.5	-0.8	1.2	0.9	1.5	1.4	1.5	1.7	1.6
Cardiovascular Disease	1.1	3.6	7.3	-1.4	-0.6	-0.2	-2.1	1.3	-2.2	-2.2	-0.6	-2.5	-2.7	-2.3	-1.4	-2.2	-2.3	-2.2
Hypothyroidism (self reported)	0.2	0.5	1.4	1.2	0.1	0.6	-0.5	-0.5	0.7	0.7	0.5	0.5	0.8	0.7	0.8	0.7	1.0	0.9
Respiratory disease	0.2	0.4	3.3	-0.7	-0.2	0.1	-1.0	0.1	-0.2	-0.1	-1.0	-0.1	-0.0	-0.1	1.8	-0.2	0.2	-0.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.8	-1.0	-0.6	-0.5	-0.8	1.0	-1.1	-1.3	-1.6	-1.2	-2.2	-1.2	-0.5	-1.2	-1.5	-1.4
Lung FEV1/FVC ratio	0.7	3.7	7.0	-2.5	-2.6	-2.2	-0.5	1.9	-1.9	-2.4	-1.7	-0.6	-1.9	-2.2	-0.3	-2.1	-1.7	-2.0
Lung FVC	0.1	0.3	1.5	0.1	0.2	0.4	-0.5	-0.3	0.3	0.4	-1.2	0.0	1.1	0.4	0.2	0.3	0.4	0.2
Neuroticism	0.2	0.6	2.0	-0.1	0.2	1.4	-0.0	-0.1	0.6	0.6	0.1	1.0	1.3	0.7	1.1	0.6	0.9	0.8
Chronotype (morning person)	0.3	0.7	5.6	0.7	0.9	0.5	0.7	-0.1	-0.1	-0.1	2.4	-1.3	0.6	-0.2	-0.1	-0.3	-0.5	-0.1
Hair Pigment	0.1	1.5	5.2	1.3	1.3	1.5	-0.1	-1.2	1.1	0.9	1.6	-1.7	1.1	0.8	2.3	0.7	0.2	0.8
Tanning	0.3	3.3	16.4	-4.1	-2.0	-0.8	-0.5	1.6	-0.3	-0.5	-3.3	3.0	0.2	-0.1	1.9	-0.0	1.1	-0.1
Hand grip strength (left)	0.1	0.2	0.7	0.7	0.8	0.1	0.6	-0.6	0.4	0.1	0.6	-0.5	0.4	0.1	-0.3	0.1	-0.1	0.2
Number of treatments/medications taken	0.2	0.4	3.5	-0.7	-0.5	0.2	-1.0	-0.2	-0.1	-0.2	-1.9	0.2	-0.9	-0.1	0.4	-0.2	0.0	-0.1
Average weekly spirits intake	0.3	0.4	1.0	0.6	0.4	0.1	-0.1	-1.0	0.7	0.7	-0.2	-0.0	-0.2	0.7	0.9	0.7	0.6	0.8
Sensitivity / hurt feelings	0.8	1.3	4.5	0.1	0.4	1.0	0.3	-1.1	1.4	0.9	0.6	1.7	2.1	1.0	1.2	1.2	1.3	1.0
Frequency of depressed mood in last 2 weeks	0.3	0.4	3.7	-1.0	0.3	1.9	0.4	0.7	-0.2	-0.4	0.2	0.7	0.2	-0.4	0.1	-0.3	0.0	-0.3
Hearing difficulty/problems: Yes	0.1	0.2	1.3	0.1	0.5	0.8	-0.2	0.1	-0.1	0.2	0.3	-0.7	0.5	0.1	1.1	0.1	-0.2	0.1
Relative age of first facial hair	0.9	1.9	4.5	0.4	2.1	1.5	0.3	-1.4	1.3	1.2	1.8	1.2	1.1	1.1	1.9	1.4	1.4	1.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	3.7	0.0	0.1	-0.7	1.8	-1.6	1.2	0.8	1.2	1.9	0.7	0.9	0.3	1.1	1.2	0.8
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.8	-0.0	-0.2	-0.0	-0.9	0.2	-0.2	-0.6	-0.0	-0.5	-0.1	-0.7	0.0	-0.5	-0.5	-0.4
Ever had hysterectomy (womb removed)	0.1	0.1	1.2	0.5	0.3	0.2	1.1	-0.5	0.0	0.1	0.1	-0.1	0.2	0.1	0.0	0.1	0.2	0.2
Systolic blood pressure, automated reading	0.9	2.6	6.8	-1.1	-1.7	-2.6	1.7	1.5	-1.8	-1.6	0.6	-0.3	-1.6	-1.5	-2.1	-1.6	-1.4	-1.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	3.7	0.2	1.4	1.9	1.5	-0.7	0.5	0.6	0.7	0.4	0.2	0.6	1.0	0.6	0.4	0.5
Angina	3.0	3.9	6.7	1.1	1.7	1.8	2.6	-2.0	2.0	2.0	1.5	2.4	1.6	2.1	1.8	2.1	2.5	2.2
Medication for hormone replacement therapy	0.2	0.2	0.6	0.8	0.2	-0.2	-0.4	-0.0	0.4	0.6	-0.5	0.4	-0.1	0.6	0.2	0.5	0.4	0.8
Vitamin and mineral supplements	0.3	0.3	4.0	0.2	0.2	0.1	-0.1	0.0	0.0	0.2	-2.0	0.1	-0.8	0.2	-0.4	0.2	0.3	0.1
Supplements: Zinc	0.4	0.5	1.5	-0.2	-0.5	0.5	0.9	0.2	-0.8	-0.6	-0.4	-1.2	-0.9	-0.6	0.4	-0.7	-0.9	-0.6
Medication: Co-codamol	0.5	0.6	2.0	-1.4	-0.8	-0.1	0.5	0.7	-0.7	-1.1	-0.9	-0.1	-0.6	-1.0	-0.4	-0.9	-0.7	-0.8
Medication: Metformin	0.2	0.3	1.0	-0.0	-0.3	0.2	-0.3	0.4	-0.4	-0.5	-1.0	-0.9	-1.0	-0.4	0.1	-0.5	-0.7	-0.5
Diabetes (father)	3.1	3.8	6.2	-2.3	-2.0	-0.6	-0.1	2.2	-2.4	-2.4	-1.1	-1.8	-1.9	-2.3	-1.3	-2.5	-2.2	-2.2
Diabetes (mother)	0.3	0.4	2.7	-0.6	-0.4	-0.1	0.4	0.4	-0.6	-0.5	-1.6	-0.3	-0.7	-0.6	-0.2	-0.5	-0.4	-0.6
Severe depression (siblings)	1.9	2.2	4.8	-1.7	-2.2	-1.0	-1.9	1.8	-1.6	-1.6	-2.1	-0.5	-0.3	-1.4	-0.8	-1.6	-0.9	-1.2
Pack years adult smoking proportion	1.0	1.6	2.8	0.5	1.2	1.6	0.8	-1.2	1.3	1.3	0.3	1.7	1.1	1.4	1.7	1.3	1.3	1.3
Impedance of leg (right)	2.2	10.9	16.9	2.9	2.5	3.1	1.3	-3.0	3.5	3.8	0.1	3.6	4.1	3.9	3.3	3.8	4.1	3.9
Leg fat-free mass (left)	1.4	7.3	11.6	-2.9	-2.5	-2.4	-0.3	2.6	-3.0	-3.1	-0.2	-2.8	-3.0	-3.2	-2.2	-3.1	-3.4	-3.3
Trunk fat percentage	0.1	0.4	1.1	-0.6	-0.3	0.4	-0.3	0.6	-0.8	-0.7	0.7	-1.1	0.3	-0.7	0.2	-0.8	-0.8	-0.8
Hand grip strength (right)	0.1	0.2	0.9	0.9	0.6	-0.4	0.2	-0.5	0.5	0.3	0.9	-0.1	-0.2	0.3	-0.6	0.3	0.2	0.3
Townsend deprivation index at recruitment	1.3	1.8	4.5	1.7	0.8	-0.0	2.1	-1.7	1.5	1.6	1.0	0.8	1.1	1.5	0.4	1.5	1.3	1.5
Current tobacco smoking	0.2	0.3	1.7	-0.5	0.6	0.7	0.7	-0.6	0.6	0.2	-0.5	0.5	-0.2	0.2	1.3	0.4	0.3	0.3
Average weekly fortified wine intake	0.2	0.3	2.8	0.3	-0.4	-0.4	1.7	-0.3	0.4	0.2	-0.2	-0.3	0.2	0.3	0.4	0.3	0.3	0.4
Maternal smoking around birth	0.4	0.6	4.3	0.8	1.1	-0.4	0.1	-1.0	0.3	0.1	2.1	0.2	0.6	0.1	-0.7	0.3	0.1	0.0
Fed-up feelings	0.2	0.3	1.3	-1.0	-0.9	0.3	0.1	0.9	-0.4	-0.1	-0.1	0.5	1.2	-0.1	0.6	-0.2	0.0	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.6	-0.8	0.4	1.0	-1.2	0.4	-0.0	-0.1	0.3	0.5	0.6	-0.1	0.8	-0.1	-0.1	-0.3
Relative age voice broke	0.9	1.4	5.1	0.7	1.2	2.3	0.9	-0.9	1.1	1.3	0.0	0.6	0.3	1.2	1.9	1.2	1.2	1.3
Taking other prescription medications	0.6	0.9	4.3	-1.4	-1.4	-0.8	-0.3	0.5	-0.6	-0.8	-2.1	0.3	-1.0	-0.7	0.6	-0.6	-0.1	-0.6
Age when periods started (menarche)	0.8	2.0	3.9	1.5	0.9	1.0	1.1	-1.4	1.5	1.5	-0.2	1.6	0.7	1.6	2.0	1.5	1.9	1.8
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.8	0.2	0.9	1.3	-1.2	-1.3	0.3	0.1	-0.3	-0.6	-0.3	0.1	0.9	0.2	0.2	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.3	-0.5	0.2	-0.6	-0.0	-0.3	-0.3	-0.6	0.4	0.2	0.4	-0.5	-1.1	-0.3	-0.3	-0.6
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.1	0.6	0.7	0.4	1.3	-1.8	1.4	1.0	1.1	1.5	-0.1	1.0	0.7	1.2	1.1	0.8
Qualifications: CSEs or equivalent	1.2	1.6	3.6	1.5	1.4	1.9	0.4	-1.4	1.3	1.5	0.5	0.4	1.3	1.4	0.7	1.4	1.1	1.3
Serious illness, injury or assault to yourself	0.2	0.2	1.0	-0.4	-1.0	0.2	-0.5	0.9	-0.2	-0.1	-0.4	0.6	0.3	0.1	0.2	-0.2	0.6	0.3
High blood pressure	2.0	5.7	9.0	-2.5	-2.0	-0.7	-1.5	2.4	-3.0	-2.7	-1.1	-2.4	-2.8	-2.8	-2.0	-2.8	-2.8	-2.8
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.5	0.8	0.8	1.2	-0.1	-1.0	1.5	1.6	-0.6	1.2	1.2	1.7	1.8	1.5	1.9	1.8
Multivitamins +/- minerals	0.6	0.8	2.2	-1.1	-1.1	-1.0	-1.0	0.7	-0.7	-1.0	1.5	-0.5	0.3	-1.0	-0.1	-0.9	-1.0	-0.9
Stomach or abdominal pain in last month	2.9	3.6	7.0	0.9	1.6	1.9	1.7	-1.9	2.1	2.0	0.8	1.3	2.4	1.9	2.7	2.2	2.1	2.1
Supplements: Glucosamine	0.3	0.4	1.7	-0.1	-0.5	-1.3	-0.2	0.2	-0.5	-0.7	0.5	-0.3	-1.0	-0.7	-0.9	-0.7	-0.3	-0.7
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	4.8	1.2	1.5	1.0	1.3	-2.2	1.8	1.4	1.2	0.6	1.1	1.4	2.0	1.5	1.3	1.3
Medication: Atenolol	0.7	0.9	4.1	0.7	1.7	1.6	2.0	-1.4	0.6	0.5	0.3	-0.4	-0.2	0.3	0.5	0.5	0.1	0.3
Medication: Levothyroxine sodium	0.4	0.7	2.2	0.3	-0.8	-0.4	-1.5	0.9	-0.7	-0.8	-0.4	-1.3	-0.9	-0.8	0.2	-0.9	-0.6	-0.6
Sitting height	0.1	0.6	2.0	-0.2	-0.1	0.5	1.4	1.0	-0.8	-0.4	1.0	-1.4	-0.1	-0.5	0.6	-0.6	-1.1	-0.8
Chronic bronchitis/emphysema (father)	1.0	1.1	2.6	-0.9	-1.4	-1.1	-1.5	1.6	-1.3	-1.0	-0.1	-0.4	0.0	-0.9	-1.0	-1.1	-1.1	-1.1
High blood pressure (mother)	0.7	1.0	2.2	-0.5	-1.5	-1.4	-0.8	1.4	-0.9	-0.7	-0.3	-0.3	-1.3	-0.7	-1.4	-0.8	-0.7	-0.8
Body mass index (BMI)	1.4	5.9	9.6	-1.8	-1.5	-1.8	-2.4	2.1	-2.8	-2.7	0.5	-3.0	-2.3	-2.9	-2.5	-2.9	-3.1	-2.9
Impedance of leg (left)	2.1	10.2	15.9	3.0	2.7	3.2	1.0	-2.8	3.3	3.6	0.4	3.3	4.0	3.7	3.2	3.6	3.9	3.8
Leg predicted mass (left)	1.4	7.3	11.8	-2.9	-2.5	-2.4	-0.2	2.6	-3.0	-3.1	-0.2	-2.8	-3.0	-3.2	-2.1	-3.1	-3.4	-3.3
Trunk fat mass	0.4	1.9	4.5	-1.3	-0.9	-0.3	-0.6	1.3	-1.7	-1.6	0.7	-2.1	-0.7	-1.7	-0.6	-1.7	-1.9	-1.7
Waist circumference	0.8	2.8	7.2	-1.4	-1.1	-0.9	-0.6	1.3	-1.9	-1.9	-0.2	-2.7	-1.4	-2.1	-0.8	-2.0	-2.3	-2.1
Number of incorrect matches in round	1.0	1.7	4.9	-1.5	-1.3	-0.5	-1.2	1.3	-1.3	-1.1	-2.2	-0.9	-1.7	-1.1	-0.4	-1.2	-1.3	-1.2
Past tobacco smoking	0.3	0.6	3.0	-0.1	-0.0	-1.7	-0.1	-0.2	-0.5	-0.6	0.5	-0.6	-0.9	-0.6	-1.2	-0.5	-1.2	-0.7
Alcohol usually taken with meals	0.1	0.1	0.2	0.3	0.5	0.5	-0.5	-0.3	0.2	0.1	0.2	0.4	-0.2	0.0	0.1	0.1	0.4	0.1
Nervous feelings	1.8	3.3	4.9	2.1	1.3	2.2	0.5	-1.4	1.9	2.2	0.9	1.4	1.4	2.2	2.1	2.0	2.2	2.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	4.6	-0.1	0.2	2.1	-0.4	0.6	0.0	0.0	-0.5	0.5	0.4	0.1	1.4	-0.0	0.4	0.1
Hearing difficulty/problems with background noise	0.2	0.3	1.0	-0.8	-0.4	-0.0	1.0	0.3	-0.2	-0.4	-0.5	-0.6	0.2	-0.4	0.6	-0.4	-0.6	-0.5
Hair/balding pattern: Pattern 2	1.5	1.9	3.9	1.4	0.8	0.7	1.6	-0.6	1.4	1.4	2.0	1.5	1.9	1.5	0.9	1.3	1.5	1.5
Had menopause	1.2	1.5	3.7	0.8	1.2	0.3	0.9	-1.0	1.5	1.1	1.9	1.7	1.3	1.0	1.0	1.2	1.4	1.2
Had other major operations	0.6	0.7	2.0	0.9	1.3	1.4	1.4	-0.8	0.6	0.3	1.2	-0.8	0.5	0.1	0.7	0.4	-0.2	-0.0
Forced vital capacity (FVC)	0.1	0.4	2.2	0.3	0.1	0.8	0.3	0.2	0.1	0.4	-1.5	-0.5	0.9	0.4	0.9	0.2	0.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.9	-0.7	-0.5	-1.2	0.4	0.3	-0.7	-0.9	-0.1	0.1	-0.6	-0.8	-1.7	-0.7	-0.6	-0.8
Ever unenthusiastic/disinterested for a whole week	4.4	5.4	11.6	-3.0	-3.4	-1.3	-1.8	2.9	-2.6	-2.5	-2.5	-0.6	-2.0	-2.3	-2.0	-2.5	-1.7	-2.1
Qualifications: None of the above	0.1	0.2	0.6	0.1	0.0	0.6	-0.6	0.5	-0.4	-0.5	-0.2	-0.4	0.3	-0.4	0.8	-0.4	-0.2	-0.2
Financial difficulties in last 2 years	0.2	0.3	2.4	-0.2	0.1	-0.3	-0.8	-0.3	-0.0	-0.3	-0.2	-0.4	-1.5	-0.3	-0.8	-0.3	-0.5	-0.3
Mouth/teeth dental problems	0.9	1.3	3.5	-0.1	-0.8	-0.2	-1.9	1.8	-1.4	-0.8	-0.2	-1.6	-0.6	-1.0	-1.0	-1.3	-1.3	-1.1
Heart attack	0.2	0.2	1.2	-0.3	0.3	1.1	1.1	0.1	0.1	0.2	-0.1	0.4	-0.4	0.3	0.6	0.1	0.4	0.3
Allergy	0.3	0.7	2.7	0.3	-0.2	-1.0	0.5	0.6	-0.6	-0.6	1.5	-0.5	-0.6	-0.7	-1.7	-0.7	-1.0	-0.7
Pain all over the body in last month	0.3	0.4	1.8	-0.8	-0.7	0.4	1.3	0.8	-0.4	-0.0	-0.7	-0.1	-0.1	0.1	1.1	-0.1	0.0	0.0
Diabetes (self-reported)	0.4	0.6	1.3	-1.1	0.0	0.1	-0.3	0.4	-0.6	-0.8	-0.9	-1.0	-0.9	-0.8	-0.2	-0.7	-1.0	-1.1
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	3.5	1.3	0.8	-0.0	0.8	-1.2	1.7	1.7	0.3	1.8	1.0	1.8	1.3	1.7	1.8	1.9
Medication: Ramipril	0.2	0.3	1.7	-0.3	0.2	0.5	-0.3	0.3	0.0	0.1	-1.0	0.9	0.2	0.0	1.3	0.2	0.4	0.2
Medication: Simvastatin	5.8	8.5	14.0	3.7	3.2	2.4	2.2	-3.0	3.1	3.4	2.7	1.6	2.6	3.3	2.1	3.2	3.0	3.3
Fluid intelligence score	4.0	8.2	11.6	2.2	3.2	2.1	2.1	-3.3	3.3	3.1	1.1	2.9	2.3	3.1	3.4	3.3	3.3	3.2
Illnesses of siblings	0.4	0.5	2.8	0.2	0.2	0.0	1.6	0.1	0.4	0.4	0.6	0.8	1.7	0.5	0.1	0.4	0.4	0.4
Neuroticism score	0.4	0.8	3.5	0.1	0.3	1.8	-0.1	-0.0	0.6	0.6	0.2	1.0	1.9	0.7	1.2	0.7	0.9	0.7
Weight	1.2	5.9	10.1	-2.5	-1.9	-1.6	-1.0	2.3	-2.9	-2.8	0.0	-3.0	-2.3	-3.0	-1.9	-2.9	-3.2	-3.0
Impedance of arm (right)	4.1	18.9	26.6	3.6	3.2	4.1	3.7	-4.1	4.9	4.8	0.9	4.6	4.8	5.0	4.5	5.0	5.2	5.0
Arm fat percentage (right)	0.2	0.7	1.7	-0.5	-0.2	-0.2	-0.8	0.5	-0.9	-0.8	1.3	-1.3	-0.2	-0.9	-0.7	-0.9	-1.1	-1.0
Trunk fat-free mass	2.0	11.6	18.9	-3.4	-2.8	-2.8	-0.6	3.3	-3.8	-3.9	-0.3	-3.7	-3.9	-4.0	-3.1	-4.0	-4.3	-4.1
Hip circumference	0.6	2.8	7.2	-1.0	-0.8	-0.5	-1.2	1.5	-1.9	-1.7	1.8	-2.7	-1.0	-1.9	-1.3	-1.9	-2.4	-2.0
Time employed in main current job	0.1	0.1	0.3	0.6	-0.0	0.0	0.3	-0.3	0.1	0.2	-0.3	0.3	0.2	0.2	-0.5	0.2	0.0	0.1
Alcohol intake versus 10 years previously	0.2	0.2	1.4	0.3	-0.2	0.2	-0.6	-0.1	0.4	0.3	0.4	-0.1	1.2	0.4	0.9	0.3	0.1	0.5
Father’s age at death	0.1	0.1	0.6	0.0	-0.2	0.0	0.7	0.4	-0.2	-0.1	0.4	-0.8	-0.5	-0.2	-0.3	-0.2	-0.4	-0.3
Worrier / anxious feelings	0.3	0.5	1.7	-0.7	-0.3	0.7	-0.2	1.3	-0.9	-0.8	0.1	-0.5	-0.0	-0.9	-0.6	-0.9	-0.7	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.3	0.2	0.8	1.8	-0.2	-0.3	0.8	0.8	0.0	0.9	1.0	0.8	2.1	0.8	1.0	0.8
Falls in the last year	0.8	1.1	2.0	0.3	1.4	1.4	0.9	-1.1	1.0	0.9	-0.3	1.1	1.4	1.0	1.0	1.1	1.0	0.9
Hair/balding pattern: Pattern 3	1.7	2.5	4.4	-1.1	-1.8	-1.6	-1.4	1.7	-1.9	-1.7	-1.4	-1.1	-2.1	-1.7	-1.2	-1.7	-1.5	-1.6
Number of live births	0.1	0.2	1.0	0.1	0.2	-0.5	0.0	-0.5	0.4	0.2	1.0	0.2	0.5	0.2	0.2	0.3	0.4	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	3.3	0.4	0.1	0.9	-0.2	0.1	0.1	0.2	-1.8	-0.6	0.4	0.3	1.2	0.1	0.2	0.2
Pulse rate	0.7	1.2	3.8	-0.4	-2.0	-1.9	-0.7	1.3	-1.0	-0.8	-1.7	-0.1	-0.6	-0.8	-1.1	-0.8	-0.8	-0.7
Happiness	0.6	0.8	3.5	-0.4	-0.1	0.4	0.3	-0.1	0.7	0.6	-1.3	1.9	0.3	0.8	1.3	0.7	1.2	0.9
Noisy workplace	1.3	1.6	2.7	-1.6	-0.4	1.0	-0.7	1.1	-1.2	-1.6	-1.4	-1.3	-0.5	-1.6	-0.4	-1.5	-1.6	-1.6
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.7	0.2	0.8	-0.1	-0.1	-0.6	0.1	-0.2	0.5	-1.0	-1.3	-0.4	0.1	-0.1	-0.6	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.1	-0.8	1.0	1.2	0.7	-1.4	1.2	0.9	0.4	1.3	0.1	0.9	1.4	1.1	1.1	0.9
Mouth/teeth dental problems: Dentures	1.3	2.3	10.5	0.1	-0.2	-0.4	3.2	-1.2	1.3	1.0	0.4	2.7	1.5	1.3	0.8	1.3	1.9	1.3
Asthma	0.2	0.4	2.2	-0.7	-0.8	-0.5	-0.8	0.1	-0.3	-0.2	-1.2	0.3	0.2	-0.1	1.5	-0.2	0.3	-0.2
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	3.4	-1.8	-1.1	-0.2	-1.7	1.2	-1.3	-1.3	-1.5	-0.9	-1.3	-1.3	-0.1	-1.3	-1.2	-1.3
Medication: Cholesterol lowering	3.2	5.0	11.4	3.4	3.0	3.0	-0.0	-2.1	2.1	2.7	2.0	0.4	1.4	2.5	1.4	2.2	1.9	2.5
Depression (self-reported)	0.1	0.2	1.3	-0.1	-1.1	-0.4	-0.5	0.6	-0.2	-0.0	-0.2	0.2	-0.0	0.0	-0.3	-0.2	0.2	0.0
Medication: Lansoprazole	0.3	0.4	1.2	-0.4	-1.0	-0.6	-1.1	0.6	-0.5	-0.6	-0.8	-0.1	-0.4	-0.5	0.3	-0.6	-0.1	-0.4
Prospective memory result	4.1	5.1	12.1	-1.3	-1.7	-1.2	-2.2	2.7	-2.4	-2.3	-0.5	-3.5	-1.6	-2.5	-2.2	-2.6	-2.9	-2.6
Lung cancer (father)	0.4	0.5	2.2	0.2	0.8	0.2	0.3	0.4	-0.4	-0.8	1.5	-0.1	-0.5	-0.9	-1.0	-0.7	-0.7	-0.9
Illnesses of mother	0.1	0.1	0.4	-0.1	0.4	0.3	-0.5	-0.4	0.1	-0.2	-0.6	-0.1	-0.1	-0.1	0.4	-0.0	0.0	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	3.5	-0.4	-0.6	0.3	-0.5	0.7	-0.4	-0.4	-1.9	-0.7	0.3	-0.3	0.2	-0.4	-0.5	-0.4
Pulse wave Arterial Stiffness index	0.3	0.3	3.1	0.2	-0.1	-0.5	-1.8	0.3	-0.2	-0.3	-0.2	-0.7	-0.3	-0.4	-0.1	-0.4	-0.4	-0.2
Impedance of arm (left)	3.8	17.5	25.0	3.2	2.9	4.1	4.0	-3.8	4.5	4.5	0.6	4.6	4.5	4.7	4.5	4.8	5.0	4.6
Arm fat mass (right)	0.7	2.9	5.2	-1.5	-1.2	-1.0	-1.1	1.6	-2.0	-2.0	0.7	-2.3	-1.5	-2.1	-1.3	-2.1	-2.3	-2.1
Trunk predicted mass	2.1	11.9	19.4	-3.5	-2.9	-2.9	-0.7	3.3	-3.8	-3.9	-0.3	-3.7	-3.9	-4.1	-3.1	-4.0	-4.4	-4.1
Standing height	0.1	1.1	7.1	-1.6	-1.0	0.2	2.7	0.8	-0.7	-0.7	-0.9	-0.5	-0.5	-0.7	0.8	-0.6	-0.8	-0.9
Length of working week for main job	1.3	1.4	4.1	0.7	1.3	2.0	0.7	-1.4	1.2	1.2	-0.2	1.1	0.6	1.1	1.9	1.3	1.1	1.0
Exposure to tobacco smoke at home	0.3	0.4	1.3	-0.1	-0.2	-1.1	-0.9	-0.3	0.0	-0.1	-0.3	-0.8	-0.9	-0.2	-1.1	-0.1	-0.3	-0.2
Breastfed as a baby	0.5	0.7	1.3	-0.7	-0.4	-1.1	-0.4	1.0	-1.1	-0.8	0.4	-1.1	-0.5	-0.9	-0.7	-0.9	-0.9	-0.9
Tense / ‘highly strung’	0.5	0.8	3.3	1.0	0.7	1.8	-0.2	-0.3	0.6	0.8	1.7	0.3	1.4	0.7	0.4	0.7	0.6	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.8	0.5	-0.4	0.6	0.9	0.3	0.3	0.7	0.9	0.7	0.6	0.7	0.1	0.4	0.9	0.8
Hair/balding pattern: Pattern 4	0.1	0.3	1.6	-0.5	-0.4	-0.1	1.3	-0.1	-0.5	-0.2	-0.9	-0.8	-0.7	-0.3	-0.2	-0.3	-0.7	-0.4
Birth weight of first child	0.3	0.5	1.9	1.2	0.3	0.2	-1.4	-0.5	0.6	0.6	0.4	-0.1	1.2	0.5	0.3	0.6	0.5	0.4
Peak expiratory flow (PEF)	0.4	0.9	5.0	1.3	1.0	1.7	-0.5	0.4	-0.4	-0.1	-0.2	-2.2	-0.6	-0.4	0.9	-0.4	-1.1	-0.4
Pulse wave reflection index	0.2	0.3	1.1	0.0	0.9	0.6	-1.1	-0.4	0.0	-0.2	0.7	-0.8	-0.6	-0.2	0.6	-0.2	-0.4	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.9	-0.5	-0.3	0.1	-0.8	0.2	0.3	0.1	-0.2	1.4	0.9	0.2	-0.1	0.2	0.7	0.2
Loud music exposure frequency	0.9	1.0	3.8	-1.3	-0.6	-0.9	-2.0	0.9	-0.8	-1.0	-0.7	-1.0	-0.8	-1.1	-0.3	-1.0	-0.9	-0.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.5	-1.0	0.3	-0.5	-0.6	-0.4	-0.3	-0.6	-0.4	-0.8	-1.2	-0.8	-0.6	-0.5	-0.8	-0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.7	-1.6	-0.4	-0.5	0.4	-0.2	-0.2	-0.6	-1.1	0.5	-0.4	-0.5	0.4	-0.3	-0.1	-0.4
Blood clot in the leg (DVT)	1.7	2.1	4.0	-1.6	-0.8	-0.8	0.7	0.6	-1.4	-2.0	-1.1	-1.3	-1.5	-2.0	-1.4	-1.7	-1.9	-2.0
Medication: Paracetamol	0.4	0.7	1.6	-0.8	-1.1	-0.1	-0.9	0.8	-0.9	-0.7	-0.7	-1.2	-1.3	-0.6	-0.7	-0.9	-0.7	-0.5
Headache pain in last month	0.1	0.2	1.5	0.6	0.3	1.2	0.2	-0.1	0.3	0.6	-0.0	-0.6	0.5	0.4	0.3	0.4	0.3	0.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	4.0	-1.0	-1.8	-2.0	0.4	0.9	-0.4	-0.6	-1.0	0.5	0.1	-0.5	0.0	-0.4	-0.0	-0.5
Glaucoma (self-reported)	1.4	1.7	5.2	-0.2	-0.6	-0.9	1.4	-0.6	1.2	1.1	-2.3	1.7	2.0	1.1	0.9	1.2	1.4	1.2
Gout (self-reported)	0.2	0.3	1.7	-0.6	0.4	0.1	-0.6	-0.8	0.1	-0.1	-0.4	-0.5	-1.3	-0.2	0.2	-0.1	-0.1	-0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	2.5	0.7	-0.6	0.3	-1.6	0.4	-0.1	-0.2	-0.4	-0.8	0.0	-0.2	0.6	-0.3	-0.1	-0.0
Medication: Amlodipine	0.1	0.2	1.3	0.1	0.3	-0.2	0.3	-0.0	-0.1	-0.1	1.1	0.2	-0.6	-0.2	-1.0	-0.0	-0.1	-0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.6	3.1	-0.8	-0.4	-0.1	-1.8	0.8	-0.6	-0.5	-1.3	-0.2	-0.6	-0.5	0.7	-0.5	-0.2	-0.6
Birth weight	0.9	1.9	6.3	1.8	1.5	1.0	1.8	-1.2	1.3	1.2	2.5	-0.0	1.7	1.1	0.6	1.2	0.9	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.5	3.2	-0.4	0.3	0.6	-1.8	-0.0	-0.2	-0.6	0.3	-1.3	-0.1	-0.7	0.4	-0.5	-0.9	-0.6
High blood pressure (siblings)	0.9	1.3	3.7	-0.2	-0.8	-0.6	-0.9	1.1	-1.3	-1.0	0.1	-1.8	-1.9	-1.1	-0.9	-1.2	-1.4	-1.0
Forced vital capacity (FVC), Best measure	0.1	0.4	2.4	-0.3	-0.5	0.3	-0.1	0.7	-0.4	-0.3	-1.5	-0.8	0.5	-0.2	0.2	-0.4	-0.5	-0.4
Body fat percentage	0.1	0.6	1.7	-0.3	-0.0	0.2	-0.9	0.5	-0.9	-0.7	1.1	-1.3	0.1	-0.8	-0.2	-0.8	-1.0	-0.8
Leg fat percentage (right)	0.3	1.2	5.2	-0.3	0.3	0.0	-2.3	0.4	-1.1	-1.0	1.2	-1.7	-0.1	-1.1	-1.1	-1.1	-1.4	-1.1
Arm fat-free mass (right)	2.0	10.4	17.0	-3.2	-2.6	-2.5	-1.2	3.2	-3.8	-3.7	-0.3	-3.7	-3.4	-3.9	-2.5	-3.9	-4.1	-3.9
Exposure to tobacco smoke outside home	0.7	1.0	2.8	-1.0	-0.2	-0.0	0.1	0.0	-0.7	-1.1	-1.3	-1.3	-1.7	-1.1	-0.6	-0.9	-1.2	-1.2
Comparative body size at age 10	0.5	1.4	4.9	0.0	0.2	0.1	-1.3	0.2	-1.0	-1.1	0.5	-2.2	-1.8	-1.4	-0.6	-1.2	-1.7	-1.4
Number of full brothers	1.4	1.7	4.2	0.8	2.0	1.8	-1.3	-1.4	1.3	1.1	1.1	0.5	1.3	1.1	1.7	1.2	1.1	1.2
Worry too long after embarrassment	0.3	0.6	1.3	0.2	0.4	1.1	0.6	-0.4	0.6	0.7	0.4	1.1	1.0	0.8	1.0	0.7	0.9	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.6	-0.4	-0.4	0.5	-0.2	0.9	-1.0	-0.7	0.2	-1.3	-0.6	-0.8	-0.2	-1.0	-0.8	-0.9
Wheeze or whistling in the chest in last year	0.2	0.4	2.3	-1.1	0.5	0.2	-1.5	0.0	-0.2	-0.3	0.6	-0.3	-0.8	-0.3	0.6	-0.2	-0.2	-0.4
Number of children fathered	0.3	0.3	1.8	-0.7	0.2	0.6	-0.6	1.0	-0.2	-0.1	0.8	-0.2	1.3	-0.0	0.6	-0.2	0.2	0.2
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	3.8	-1.5	-0.6	-1.0	-0.8	0.7	-1.2	-1.9	0.1	-1.6	-1.6	-1.9	-1.8	-1.7	-1.9	-1.6
Age at first live birth	1.3	2.4	3.5	-1.2	-1.7	-1.2	-0.4	1.9	-1.8	-1.5	-1.8	-1.7	-1.7	-1.5	-0.9	-1.7	-1.6	-1.5
Pulse wave peak to peak time	0.3	0.3	3.6	-0.4	-0.2	0.5	1.9	-0.2	0.0	0.2	-0.0	0.8	0.2	0.3	0.1	0.3	0.4	0.1
Health satisfaction	1.1	1.4	5.7	0.6	0.9	2.0	0.5	-0.3	0.8	1.2	0.5	1.0	0.9	1.2	2.4	1.0	1.4	1.2
Shortness of breath walking on level ground	0.2	0.2	1.0	0.2	0.0	0.3	0.0	-0.2	0.3	0.3	1.0	0.3	0.9	0.3	0.3	0.2	0.3	0.4
Qualifications: College or University degree	0.1	0.4	1.3	0.5	0.8	0.5	0.2	-0.9	0.7	0.7	1.1	0.2	0.3	0.7	0.0	0.7	0.6	0.6
Eye problems/disorders: None of the above	1.4	1.6	3.3	-0.0	-0.1	-0.6	-1.3	1.1	-1.2	-1.4	1.7	-1.8	-0.8	-1.5	-1.5	-1.4	-1.7	-1.4
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.3	1.5	1.4	0.9	-0.2	-1.0	1.3	1.2	0.6	0.1	0.8	1.1	1.3	1.1	1.1	1.3
Emphysema/chronic bronchitis	0.7	0.8	1.7	1.1	1.3	1.1	-0.4	-0.9	0.9	1.1	0.8	-0.2	0.6	0.9	0.8	0.9	0.7	0.9
Medication for pain relief, constipation, heartburn	1.6	2.7	6.0	1.6	1.3	-0.3	2.5	-1.4	1.8	1.6	1.5	1.6	2.5	1.5	1.1	1.7	1.6	1.5
Neck or shoulder pain in last month	0.4	0.5	4.5	-0.8	-0.8	0.2	-2.1	0.5	-0.4	-0.5	-0.4	0.4	-0.5	-0.4	-0.2	-0.4	-0.2	-0.4
Medication: Blood pressure	0.4	0.8	2.0	-1.4	-0.3	0.2	0.1	0.5	-1.1	-1.1	-0.4	-0.4	-0.8	-1.2	-1.0	-1.1	-1.0	-1.1
Angina (self-reported)	2.7	3.5	6.3	1.1	1.7	1.8	2.5	-1.9	1.9	1.8	1.6	2.2	1.4	1.9	1.5	1.9	2.3	2.1
Migraine (self-reported)	0.6	0.7	5.0	-0.6	-1.4	-0.2	0.3	1.2	-0.6	-0.3	-2.2	-0.4	-0.4	-0.2	0.8	-0.5	-0.0	-0.2
Medication: Ibuprofen	2.4	2.9	6.2	-2.5	-2.3	-1.1	-1.5	1.7	-1.7	-1.8	-2.3	-0.7	-1.8	-1.6	-1.0	-1.7	-1.4	-1.7
Medication: Allopurinol	0.2	0.3	1.0	0.1	0.9	0.3	-0.6	-0.7	0.2	0.2	0.9	-0.7	-1.0	0.1	0.8	0.0	0.0	0.0
Medication: Omeprazole	0.4	0.5	3.1	-0.3	0.4	1.6	0.3	0.0	-0.6	-0.4	0.3	-0.5	-1.8	-0.4	0.4	-0.5	-0.2	-0.4
Medication: Seretide 50 evohaler	0.3	0.3	1.9	-0.5	-0.7	-0.1	-0.1	0.3	-0.2	-0.1	-1.4	-1.1	-0.4	-0.1	1.0	-0.2	-0.1	-0.0
Mean time to correctly identify matches	0.2	0.4	1.2	-0.9	-1.0	-0.9	0.7	0.2	0.2	0.3	-1.1	0.8	0.4	0.4	0.5	0.3	0.6	0.4
Heart disease (mother)	0.5	0.6	2.0	0.1	0.0	0.1	1.4	-0.6	0.6	0.7	0.5	1.1	0.5	0.8	1.1	0.7	0.9	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.8	5.5	1.7	1.3	0.5	-0.1	-1.5	2.0	2.3	-0.2	1.3	1.8	2.3	1.5	2.2	2.2	2.1
Whole body fat mass	0.7	2.7	5.4	-1.4	-1.0	-0.7	-1.2	1.5	-2.0	-1.9	0.9	-2.3	-1.2	-2.0	-1.1	-2.0	-2.2	-2.0
Leg fat mass (right)	0.6	2.5	4.9	-1.2	-0.7	-0.7	-1.9	1.3	-1.8	-1.7	0.8	-2.2	-0.9	-1.9	-1.2	-1.8	-2.1	-1.9
Arm predicted mass (right)	2.4	12.5	19.2	-3.5	-3.0	-2.9	-1.4	3.7	-4.2	-4.1	-0.3	-3.7	-3.5	-4.2	-3.0	-4.2	-4.4	-4.3
Pulse rate, automated reading	0.4	1.3	4.2	-0.5	-0.4	0.2	-0.6	0.8	-1.4	-1.1	-1.1	-2.0	-1.1	-1.3	-1.0	-1.3	-1.7	-1.3
Alcohol intake frequency.	0.2	0.4	1.8	-0.7	-1.0	-0.8	-0.1	0.8	-0.5	-0.4	-0.7	-0.3	1.3	-0.4	0.2	-0.4	-0.5	-0.4
Comparative height size at age 10	0.5	2.6	6.3	-2.5	-1.6	-1.8	1.5	1.4	-1.6	-1.9	-1.2	-0.4	-0.7	-1.8	-1.2	-1.6	-1.8	-2.1
Number of full sisters	0.3	0.3	1.3	-0.1	0.5	0.7	-1.1	0.1	-0.0	-0.1	0.8	-0.6	0.7	-0.1	1.0	-0.3	-0.2	0.1
Suffer from ‘nerves’	1.4	2.2	5.1	1.0	0.4	1.7	-0.8	-0.3	1.2	1.8	-0.3	1.7	1.6	1.9	1.7	1.6	2.3	1.9
Overall health rating	0.2	0.4	2.1	-1.0	-0.7	0.4	-1.4	0.5	-0.4	-0.3	0.3	-0.1	-0.2	-0.4	0.8	-0.4	-0.1	-0.4
Chest pain or discomfort	0.1	0.2	1.4	-0.7	0.1	0.2	-0.7	-0.4	0.3	-0.1	-0.1	0.0	-0.7	-0.1	1.2	0.0	0.3	0.1
Had major operations	0.5	0.6	1.8	-1.0	-1.2	-1.3	-0.4	0.7	-0.9	-0.8	-0.5	-0.7	0.7	-0.8	-0.2	-0.8	-0.5	-0.8
Age at last live birth	0.5	0.7	2.9	-0.5	-1.5	-1.7	0.8	1.0	-0.6	-0.3	-1.4	0.1	-0.8	-0.3	-0.2	-0.5	-0.1	-0.2
Family relationship satisfaction	0.8	1.0	2.2	0.3	0.7	0.6	1.4	-1.0	1.1	1.0	-0.7	1.5	0.5	1.1	0.2	1.2	1.2	1.0
Leg pain on walking	0.1	0.1	0.5	-0.1	-0.5	0.5	-0.0	0.5	-0.0	0.0	-0.1	0.3	0.4	0.1	0.7	-0.1	0.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	4.2	1.4	1.4	1.1	0.3	-1.0	0.7	0.7	2.1	-0.3	0.1	0.7	0.5	0.5	0.3	0.6
Commuting to job workplace: Car/motor vehicle	0.8	0.9	10.8	0.5	0.3	1.2	-3.3	-0.0	-0.2	-0.2	-0.6	-0.7	0.1	-0.3	0.4	-0.2	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	1.0	0.8	-0.0	0.2	-0.4	-0.3	0.1	0.3	-1.0	0.3	0.4	0.3	-0.1	0.3	0.2	0.1
Medication: Aspirin	0.3	0.4	2.7	0.3	0.7	1.7	0.6	-0.5	0.3	0.4	0.5	-0.1	0.1	0.4	0.9	0.3	0.2	0.4
Supplements: Vitamin C	0.1	0.2	0.7	-0.3	-0.6	-0.3	0.8	0.1	0.1	0.0	0.6	0.6	0.0	0.0	0.5	0.0	0.4	0.1
Knee pain experienced in last month	0.1	0.2	0.6	-0.3	-0.6	-0.3	-0.8	0.6	-0.0	-0.2	-0.7	0.2	0.4	-0.0	0.4	-0.1	0.0	0.1
Hypertension (Self-reported)	1.7	4.8	7.3	-2.3	-1.8	-0.5	-1.5	2.1	-2.7	-2.5	-1.2	-2.1	-2.6	-2.5	-1.9	-2.6	-2.5	-2.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	6.2	-1.0	-0.3	0.2	-0.1	-0.3	0.1	-0.2	-2.5	0.2	-1.3	-0.1	0.9	0.0	0.0	-0.1
Illnesses of father: Heart disease	0.4	0.6	2.1	1.4	0.5	0.4	-0.4	-0.5	0.6	0.8	0.8	0.9	0.4	0.8	0.4	0.7	1.0	0.8
Illnesses of siblings: Diabetes	0.6	0.7	2.2	0.1	0.8	0.4	0.7	-1.5	0.8	0.6	-1.2	0.1	-1.4	0.5	1.0	0.7	0.4	0.6
Smoking status: Previous	0.3	0.4	1.9	0.5	-0.2	1.4	-0.6	0.5	0.2	0.5	-0.5	0.2	0.8	0.5	0.9	0.3	0.9	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	2.2	0.2	0.9	1.5	-0.1	-0.5	0.5	0.5	-0.1	-0.8	0.3	0.4	0.4	0.4	-0.0	0.3
Whole body fat-free mass	2.0	11.2	17.9	-3.4	-2.9	-2.9	-0.7	3.3	-3.7	-3.8	-0.3	-3.6	-3.6	-4.0	-3.0	-3.9	-4.2	-4.0
Leg fat-free mass (right)	1.3	6.8	11.2	-2.8	-2.2	-2.2	-0.2	2.5	-2.9	-3.0	-0.1	-2.9	-2.9	-3.2	-2.0	-3.0	-3.3	-3.2
Arm fat percentage (left)	0.2	0.7	1.8	-0.5	-0.2	0.0	-0.7	0.6	-1.0	-0.9	1.3	-1.4	-0.3	-1.0	-0.5	-0.9	-1.2	-1.0
Average weekly red wine intake	0.2	0.3	1.3	1.2	0.2	0.1	0.7	-0.2	0.6	0.4	1.2	0.2	0.7	0.4	0.4	0.4	0.5	0.4
Handedness (chirality/laterality): Left-handed	0.7	0.9	6.0	0.8	1.4	2.5	0.9	-0.0	0.4	0.3	0.9	-0.5	0.9	0.3	0.9	0.2	0.1	0.2
Mood swings	0.3	0.6	2.2	-0.9	-1.1	0.4	-0.5	1.5	-0.8	-0.7	-0.1	0.0	1.1	-0.6	0.2	-0.8	-0.4	-0.5
Loneliness, isolation	0.1	0.1	0.9	-0.7	-0.3	0.5	-1.0	0.1	0.1	-0.2	-0.2	0.6	0.0	-0.1	-0.1	-0.1	0.1	-0.2
Long-standing illness, disability or infirmity	0.3	0.5	1.2	0.3	-0.4	0.4	-0.1	-0.4	0.7	0.7	-0.9	1.1	0.5	0.9	0.7	0.8	1.0	0.8
Ever had bowel cancer screening	0.8	1.0	3.8	-0.7	-1.6	-1.4	-1.1	0.7	-0.8	-0.7	-1.9	0.2	-0.9	-0.6	-0.7	-0.7	-0.3	-0.7
Diabetes diagnosed by doctor	0.5	0.8	2.0	-1.1	-0.0	0.5	-0.2	0.5	-0.8	-1.0	-1.1	-1.4	-1.2	-1.0	0.3	-0.9	-1.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.2	-0.4	-0.3	-0.7	0.2	-0.0	-0.1	-0.4	-0.2	0.5	-0.5	-0.3	-1.1	-0.2	0.0	-0.3
Friendships satisfaction	1.0	1.3	3.9	0.4	0.4	1.3	2.0	-0.3	0.8	1.1	-0.6	1.7	0.9	1.2	1.1	1.1	1.5	1.2
Qualifications: nursing, teaching	1.3	2.1	5.2	-1.6	-0.1	0.1	-0.1	0.9	-1.5	-1.6	-0.6	-2.3	-2.2	-1.8	0.3	-1.6	-1.9	-1.8
Commuting to job workplace: Walk	0.3	0.4	2.1	0.6	0.4	-0.3	1.5	-0.7	0.4	0.4	1.2	0.2	-0.3	0.3	-0.0	0.4	0.2	0.2
Eye problems/disorders: Cataract	0.3	0.4	2.3	-0.2	-0.1	0.4	0.7	-0.2	0.3	0.2	-1.5	1.0	0.0	0.3	0.8	0.3	0.7	0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.3	0.6	1.0	0.4	0.2	-0.4	0.3	-0.1	1.1	-0.8	0.1	-0.1	-0.2	0.0	-0.6	-0.0
Medication for cholesterol	0.3	0.4	2.0	0.3	0.3	-0.0	-0.0	-0.2	0.4	0.6	1.3	0.2	1.4	0.6	0.2	0.5	0.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.0	0.7	0.2	0.2	-0.1	-0.9	0.8	1.0	0.2	1.0	0.3	1.0	0.2	0.9	1.0	1.0
Back pain experienced in last month	2.0	2.9	7.3	-1.2	-2.1	-2.1	-1.3	2.1	-1.7	-1.7	-0.7	-0.6	-1.5	-1.6	-2.7	-1.8	-1.5	-1.6
Mineral and other dietary supplements	0.4	0.5	1.1	-0.1	0.4	0.8	0.5	-0.9	0.8	0.8	-0.3	1.1	0.7	0.9	0.1	0.9	0.7	0.7
Breast cancer (self-reported)	0.2	0.3	1.3	0.7	0.2	-0.7	1.1	-0.6	0.5	0.4	0.5	0.4	-0.1	0.3	-0.2	0.4	0.3	0.3
Asthma (self-reported)	0.2	0.4	2.6	-0.4	-0.6	-0.3	-0.6	-0.1	0.0	0.1	-1.2	0.5	0.5	0.2	1.6	0.1	0.6	0.1
Osteoporosis (self-reported)	0.6	0.8	3.1	0.1	-0.3	-0.6	1.8	-0.7	1.0	0.5	-0.4	1.6	1.0	0.7	0.3	0.7	1.0	0.7
Osteoarthritis (self-reported)	1.3	1.7	3.4	1.5	1.1	1.7	-0.5	-1.0	1.3	1.4	0.9	0.8	0.9	1.5	1.8	1.3	1.5	1.6
Medication: Aspirin	0.2	0.2	1.8	0.1	0.6	1.4	0.5	-0.3	-0.0	0.0	0.3	-0.5	-0.4	0.0	0.5	-0.0	-0.2	0.1
Medication: Gliclazide	1.9	2.1	8.2	-0.2	1.2	2.6	-0.4	0.2	-1.0	-1.4	0.8	-2.9	-0.6	-1.6	0.0	-1.3	-2.1	-1.6
Illnesses of father: None of the above (group 1)	0.8	1.0	5.6	-0.2	0.4	-0.3	2.4	-0.5	1.2	0.6	-0.2	1.5	0.9	0.7	1.3	0.8	1.0	0.8
Smoking status: Current	0.3	0.4	1.6	-0.8	0.3	0.6	1.0	-0.4	0.6	0.2	-0.9	0.8	-0.3	0.2	1.2	0.3	0.4	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.3	-0.7	-0.9	-0.7	-0.2	0.6	0.1	0.2	-1.1	0.6	1.1	0.3	-0.3	0.1	0.3	0.2
Whole body water mass	1.8	10.4	16.8	-3.3	-2.7	-2.8	-0.6	3.1	-3.6	-3.7	-0.3	-3.5	-3.5	-3.8	-2.8	-3.7	-4.1	-3.9
Leg predicted mass (right)	1.3	6.7	10.9	-2.8	-2.2	-2.2	-0.1	2.4	-2.8	-3.0	-0.1	-2.7	-2.9	-3.1	-2.0	-3.0	-3.3	-3.2
Arm fat mass (left)	0.8	3.2	5.5	-1.6	-1.2	-0.9	-1.1	1.7	-2.2	-2.1	0.9	-2.3	-1.5	-2.2	-1.3	-2.2	-2.4	-2.2
Number of self-reported non-cancer illnesses	1.2	2.0	4.3	0.3	0.6	2.1	0.5	-1.6	1.6	1.5	-1.1	1.2	0.8	1.6	1.9	1.6	1.7	1.6
Average weekly champagne plus white wine intake	0.4	0.6	2.9	0.0	-0.2	-0.2	1.7	-0.5	0.6	0.7	-0.1	1.3	0.1	0.9	0.2	0.8	0.9	0.8
Miserableness	1.1	1.9	7.8	0.1	0.2	0.8	0.1	-1.2	1.5	1.3	-0.2	1.5	2.8	1.4	1.9	1.4	1.6	1.4
Guilty feelings	1.3	2.0	3.2	-1.6	-1.3	0.1	-1.0	1.8	-1.5	-1.7	-0.7	-1.1	-1.3	-1.6	-1.2	-1.6	-1.8	-1.7
Wears glasses or contact lenses	0.2	0.3	1.1	-0.4	0.5	1.1	0.1	-0.1	0.2	0.3	0.8	0.2	0.5	0.3	1.0	0.3	0.3	0.2
Ever taken oral contraceptive pill	0.8	0.9	4.0	-0.5	0.2	0.7	0.3	-0.2	0.8	0.8	-1.4	2.0	0.1	1.0	0.3	0.9	1.2	1.0
Hearing aid user	0.3	0.3	0.9	-0.2	-0.7	-0.9	-0.2	0.1	0.5	0.5	-0.8	0.9	0.8	0.5	0.4	0.5	0.5	0.4
Mother’s age at death	0.5	0.7	2.2	0.3	1.0	1.3	0.7	-0.4	0.9	0.7	-0.2	0.1	1.2	0.7	1.5	0.7	0.6	0.6
Financial situation satisfaction	0.1	0.1	0.5	-0.1	0.2	0.0	0.4	-0.7	0.3	0.2	-0.2	0.5	-0.4	0.1	-0.1	0.2	-0.1	0.1
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.1	0.7	1.4	1.4	-0.0	-0.7	0.8	0.9	-0.2	0.0	1.4	0.8	1.3	0.9	0.7	0.8
Commuting to job workplace: Public transport	1.9	2.2	14.7	0.6	0.5	0.6	3.8	-0.7	1.2	1.3	0.8	2.1	0.9	1.4	0.6	1.3	1.5	1.3
Eye problems/disorders: Glaucoma	0.8	1.0	2.6	0.2	-0.2	-0.2	0.7	-0.5	1.0	1.1	-1.6	1.0	1.6	1.1	0.8	1.1	1.1	1.1
Medication: Blood pressure	0.9	1.6	3.3	-1.3	-1.2	-0.3	-0.5	1.2	-1.4	-1.4	-1.7	-0.8	-1.8	-1.4	-1.2	-1.3	-1.2	-1.4
Pain type(s) experienced in last month: Hip pain	0.4	0.5	3.9	-0.5	-0.9	0.0	-1.2	0.9	-0.5	-0.4	-2.0	-0.1	-0.2	-0.3	0.0	-0.5	-0.0	-0.1
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.2	-0.6	-1.1	-1.1	-0.9	1.8	-1.6	-1.5	-0.0	-1.5	-1.4	-1.5	-1.1	-1.7	-1.5	-1.4
High cholesterol (Self-reported)	0.5	0.9	2.5	1.6	1.4	1.1	0.5	-0.9	0.8	1.0	0.9	0.4	0.9	0.9	0.3	0.8	0.7	0.9
Medication: Bendroflumethiazide	0.4	0.6	1.6	0.1	-0.7	0.3	-0.0	1.1	-1.3	-0.6	-0.7	-1.1	-0.7	-0.7	-0.7	-0.9	-0.8	-0.6
Medication: Paracetamol	0.3	0.5	1.6	-0.9	-1.2	0.0	-1.2	0.5	-0.6	-0.5	-0.6	-0.8	-0.8	-0.4	-0.2	-0.6	-0.3	-0.3
Medication: Lisinopril	0.1	0.2	0.6	-0.7	-0.8	0.2	0.4	0.6	0.0	-0.1	-0.5	0.5	0.2	-0.0	-0.0	-0.1	0.4	0.1
Medication: Atorvastatin	1.3	1.6	3.0	-1.0	-1.0	-0.2	-0.7	1.7	-1.7	-1.5	-1.2	-1.2	-1.1	-1.5	-0.4	-1.6	-1.5	-1.4
Illnesses of father: High blood pressure	0.4	0.5	2.5	-0.8	0.4	1.6	-0.7	-0.2	-0.4	-0.2	-1.5	-0.7	-0.8	-0.2	0.1	-0.1	-0.2	-0.3
Alcohol drinker status: Never	0.5	0.6	1.7	1.3	1.2	1.0	0.7	-0.6	0.6	0.6	1.3	0.1	0.2	0.5	0.5	0.6	0.6	0.6
Ever smoked	0.4	0.8	4.9	0.3	0.5	2.2	0.2	0.2	0.6	0.7	-0.6	0.3	0.8	0.6	1.3	0.6	1.1	0.8
Basal metabolic rate	1.8	9.7	15.8	-3.1	-2.7	-2.6	-0.7	3.1	-3.6	-3.6	-0.2	-3.4	-3.3	-3.7	-2.7	-3.6	-4.0	-3.8
Leg fat percentage (left)	0.5	1.7	6.1	-0.3	0.3	-0.1	-2.5	0.6	-1.3	-1.2	1.4	-2.0	-0.3	-1.3	-1.1	-1.3	-1.6	-1.3
Arm fat-free mass (left)	2.3	11.7	19.0	-3.2	-2.6	-2.8	-1.4	3.3	-3.9	-3.9	-0.1	-3.9	-3.6	-4.1	-3.0	-4.0	-4.4	-4.1
Number of operations (self-reported)	0.3	0.5	1.3	0.1	0.8	1.1	1.1	-1.1	0.3	0.1	0.7	-0.8	1.1	0.1	1.0	0.3	0.2	0.0
Average weekly beer plus cider intake	0.2	0.3	1.9	-0.5	-0.4	-0.5	0.5	-0.0	-0.5	-0.6	-0.3	-0.2	-1.4	-0.6	-0.5	-0.6	-0.4	-0.5
Irritability	1.3	2.2	7.8	0.8	1.7	2.5	1.4	-1.0	1.2	1.1	1.1	0.2	1.8	1.0	2.8	1.1	1.1	1.1
Risk taking	0.3	0.5	2.1	-0.3	0.5	1.1	0.8	-0.6	0.7	0.2	-0.0	1.5	0.6	0.4	0.5	0.5	0.9	0.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.1	-0.6	-1.0	-0.2	1.6	0.8	0.1	0.6	-0.7	1.8	1.3	0.7	0.8	0.5	1.0	0.7
Fractured/broken bones in last 5 years	0.3	0.4	1.5	0.4	0.5	0.2	-1.0	-0.8	0.5	0.3	-0.3	-0.5	-1.2	0.4	0.8	0.3	0.2	0.5
Age started oral contraceptive pill	0.3	0.3	2.1	-0.7	0.4	0.3	1.4	-0.9	0.4	0.1	-0.8	0.4	-0.1	0.0	-0.2	0.3	0.0	-0.1
Diastolic blood pressure, automated reading	1.0	3.2	8.0	-1.2	-2.1	-2.8	-0.1	1.4	-1.9	-1.8	-0.5	-0.7	-1.9	-1.8	-2.8	-1.8	-1.8	-1.9
Ever depressed for a whole week	1.1	1.3	4.9	0.3	-0.1	0.7	-0.1	-0.8	1.1	1.2	-0.3	2.2	1.4	1.4	0.6	1.2	1.9	1.5
Unable to work because of sickness or disability	0.3	0.4	0.9	-0.7	-0.9	-0.7	-0.9	0.8	-0.5	-0.4	1.0	0.5	0.5	-0.3	-0.2	-0.4	-0.1	-0.3
Commuting to job workplace: Cycle	0.3	0.4	1.1	0.1	0.2	0.5	0.2	-0.4	0.6	0.7	-0.2	1.0	0.7	0.8	1.0	0.7	0.9	0.7
Myopia	0.9	1.3	3.7	1.2	1.7	1.9	-0.2	-1.4	1.0	1.0	1.1	-0.1	1.2	1.0	1.1	1.1	0.7	0.9
Vascular/heart problems diagnosed by doctor	1.5	4.1	6.6	2.2	1.6	0.1	1.6	-2.2	2.6	2.3	1.2	2.1	2.4	2.4	1.6	2.4	2.3	2.3
Cholesterol lowering medication	0.4	0.6	1.9	0.7	0.7	0.9	1.4	-0.7	0.7	0.6	0.4	0.9	0.3	0.6	1.1	0.6	0.8	0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.9	-0.1	0.5	1.7	0.1	-0.1	-0.4	-0.4	0.4	-0.7	-1.4	-0.4	0.9	-0.5	-0.2	-0.4
Pain experienced in last month	0.4	0.6	1.4	-0.7	0.5	-0.5	0.4	-0.1	-0.8	-1.0	0.7	-0.6	-1.2	-1.1	-0.3	-0.8	-1.0	-1.2
Supplements: Calcium	0.6	0.7	2.1	-0.4	-0.1	-0.4	1.4	-1.1	0.9	0.4	-0.7	1.4	0.3	0.5	1.0	0.7	0.9	0.6
Basal cell carcinoma (self-reported)	1.1	1.3	2.7	1.6	-0.0	0.8	0.7	-1.0	1.0	1.2	-0.5	1.6	0.9	1.3	0.6	1.2	1.5	1.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	-0.2	0.4	1.2	1.1	-0.0	0.2	0.4	-0.0	0.6	-0.1	0.5	0.9	0.3	0.6	0.5
Deep venous thrombosis (DVT) (self-reported)	1.6	2.1	3.9	-1.6	-0.8	-0.7	0.7	0.6	-1.3	-2.0	-1.1	-1.4	-1.6	-2.0	-1.1	-1.7	-1.9	-2.0
Heart disease (siblings)	0.7	0.9	5.6	-0.7	-1.0	-1.0	-2.4	0.7	-0.7	-0.7	-1.0	-0.3	-0.5	-0.7	-0.6	-0.6	-0.5	-0.8
Alcohol drinker status: Previous	0.1	0.2	0.6	0.3	0.2	0.4	0.2	-0.0	0.2	0.4	0.8	0.6	0.5	0.5	-0.2	0.3	0.5	0.4
Pack years of smoking	1.4	2.0	4.1	0.6	1.3	1.7	1.1	-1.4	1.5	1.4	0.5	1.8	1.2	1.5	2.0	1.5	1.4	1.5
Impedance of whole body	3.3	16.6	24.7	3.5	3.0	4.1	2.9	-3.6	4.3	4.5	0.5	4.4	4.8	4.7	4.3	4.6	5.0	4.7
Leg fat mass (left)	0.7	2.8	5.8	-1.2	-0.6	-0.5	-2.1	1.4	-1.9	-1.8	1.0	-2.4	-1.1	-2.0	-1.2	-2.0	-2.2	-2.0
Arm predicted mass (left)	2.2	11.4	19.3	-3.2	-2.6	-2.7	-1.5	3.3	-3.9	-3.9	-0.1	-3.9	-3.5	-4.0	-2.9	-4.0	-4.4	-4.1