[Hub]/) : Traits : Impedance of arm (right) :

chr1:16,142,960-18,074,702

Best TWAS P=2.19e-10 · Best GWAS P=4.55e-09 conditioned to 0.293

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATP13A2 0.08 0.06 lasso 5 0.08 6.9e-10 4.9 5.6 2.5e-08 -0.64 0.14 0.86 FALSE
2 GTEx Adipose Subcutaneous CROCC 0.18 0.15 enet 24 0.19 2.9e-15 -4.8 -6.3 2.7e-10 0.63 0.39 0.61 FALSE
3 GTEx Adipose Subcutaneous MST1P2 0.12 0.01 enet 20 0.04 2.1e-04 -3.9 5.5 3.4e-08 -0.40 0.07 0.11 FALSE
4 GTEx Adipose Subcutaneous RP11-108M9.5 0.25 0.12 enet 20 0.22 6.5e-18 -3.9 -5.5 3.0e-08 0.49 0.97 0.02 FALSE
5 GTEx Adipose Visceral Omentum MST1L 0.15 0.08 enet 21 0.11 1.7e-06 5.1 -6.1 8.3e-10 0.70 0.03 0.97 FALSE
6 GTEx Adrenal Gland RP11-108M9.5 0.46 0.01 enet 35 0.17 9.0e-07 -5.9 -6.1 8.4e-10 0.65 0.02 0.91 FALSE
7 GTEx Adrenal Gland RP11-108M9.4 0.39 0.01 enet 31 0.10 1.3e-04 -2.6 -6.2 5.5e-10 0.60 0.04 0.75 FALSE
8 GTEx Artery Aorta CROCC 0.20 0.18 enet 23 0.20 4.0e-11 -4.1 -5.2 2.1e-07 0.52 0.28 0.72 FALSE
9 GTEx Artery Coronary RP11-108M9.5 0.39 0.06 enet 22 0.13 4.0e-05 -3.8 -5.8 5.0e-09 0.63 0.10 0.82 FALSE
10 GTEx Artery Coronary RP11-108M9.4 0.23 -0.01 enet 13 0.01 1.1e-01 -3.9 -5.5 3.9e-08 0.61 0.06 0.57 FALSE
11 GTEx Artery Tibial CROCC 0.25 0.11 enet 36 0.14 3.6e-11 -4.8 -5.8 5.3e-09 0.53 0.43 0.56 FALSE
12 GTEx Artery Tibial MFAP2 0.15 0.06 enet 20 0.07 2.3e-06 -4.5 5.4 7.9e-08 -0.58 0.02 0.98 FALSE
13 GTEx Artery Tibial MST1L 0.21 0.08 lasso 6 0.12 5.0e-10 -4.8 -5.4 6.5e-08 0.60 0.24 0.75 FALSE
14 GTEx Artery Tibial NBPF1 0.34 0.02 lasso 8 0.05 1.1e-04 -4.6 -5.2 2.5e-07 0.57 0.23 0.42 FALSE
15 GTEx Artery Tibial RP11-108M9.5 0.29 0.09 enet 35 0.21 2.4e-16 -4.1 -5.2 2.2e-07 0.49 0.46 0.54 FALSE
16 GTEx Brain Caudate basal ganglia MFAP2 0.14 0.03 enet 20 0.01 2.0e-01 -5.1 5.3 1.4e-07 -0.71 0.06 0.40 FALSE
17 GTEx Brain Cerebellum MST1P2 0.38 0.04 enet 28 0.21 6.0e-07 -4.1 5.9 3.7e-09 -0.56 0.07 0.71 FALSE
18 GTEx Brain Cortex MST1L 0.38 0.12 enet 26 0.09 1.7e-03 5.1 -5.7 1.1e-08 0.60 0.07 0.63 FALSE
19 GTEx Brain Cortex RP11-108M9.4 0.49 0.10 lasso 8 0.15 5.3e-05 -4.1 -5.1 2.9e-07 0.36 0.12 0.15 FALSE
20 GTEx Brain Hippocampus MST1P2 0.41 0.07 lasso 6 0.19 3.4e-05 2.6 5.7 1.2e-08 -0.50 0.05 0.52 FALSE
21 GTEx Brain Hippocampus RP11-108M9.4 0.26 0.05 lasso 6 0.16 1.3e-04 -3.9 -5.3 1.1e-07 0.41 0.15 0.18 FALSE
22 GTEx Cells EBV-transformed lymphocytes MST1L 0.31 0.10 lasso 6 0.14 2.2e-05 -5.5 -5.8 5.4e-09 0.81 0.03 0.96 FALSE
23 GTEx Cells Transformed fibroblasts CROCC 0.27 0.11 lasso 11 0.16 7.3e-12 -4.1 -5.6 1.9e-08 0.58 0.65 0.34 FALSE
24 GTEx Cells Transformed fibroblasts MFAP2 0.29 0.39 enet 6 0.42 1.3e-33 -4.8 5.2 1.8e-07 -0.60 0.15 0.85 FALSE
25 GTEx Cells Transformed fibroblasts MST1L 0.09 0.02 enet 12 0.03 3.1e-03 -4.1 -5.2 2.0e-07 0.64 0.23 0.47 FALSE
26 GTEx Cells Transformed fibroblasts RP11-108M9.5 0.32 0.04 enet 18 0.16 3.1e-12 -5.3 -6.1 1.3e-09 0.57 0.08 0.91 FALSE
27 GTEx Colon Transverse CROCC 0.20 0.14 lasso 2 0.14 2.2e-07 -4.1 -5.2 2.5e-07 0.69 0.26 0.74 FALSE
28 GTEx Esophagus Gastroesophageal Junction RP11-108M9.5 0.57 0.05 enet 42 0.39 3.8e-15 -3.8 -5.8 6.3e-09 0.54 0.28 0.66 FALSE
29 GTEx Esophagus Gastroesophageal Junction RP11-108M9.4 0.53 0.10 lasso 11 0.41 6.5e-16 -2.6 -5.3 9.7e-08 0.47 0.77 0.18 FALSE
30 GTEx Esophagus Mucosa CROCC 0.14 0.08 enet 18 0.14 9.5e-10 -4.5 -6.0 1.6e-09 0.67 0.38 0.61 FALSE
31 GTEx Esophagus Mucosa MST1P2 0.32 0.06 enet 22 0.12 3.3e-08 -5.1 5.2 1.7e-07 -0.50 0.03 0.97 FALSE
32 GTEx Esophagus Mucosa MST1L 0.13 0.07 enet 23 0.07 2.7e-05 4.9 -5.7 1.0e-08 0.69 0.04 0.95 FALSE
33 GTEx Esophagus Mucosa NBPF1 0.17 0.09 enet 27 0.12 1.5e-08 -4.8 -5.4 6.1e-08 0.59 0.45 0.54 FALSE
34 GTEx Esophagus Mucosa RP11-108M9.5 0.28 0.26 lasso 7 0.31 2.9e-21 -4.1 -5.1 2.8e-07 0.50 0.91 0.08 FALSE
35 GTEx Esophagus Mucosa RP11-108M9.4 0.24 0.16 lasso 5 0.20 1.1e-13 -4.1 -5.4 5.8e-08 0.48 0.44 0.56 FALSE
36 GTEx Esophagus Muscularis MFAP2 0.14 0.15 lasso 3 0.12 8.8e-08 -5.5 5.7 1.0e-08 -0.77 0.02 0.98 FALSE
37 GTEx Esophagus Muscularis RP11-108M9.5 0.35 0.14 enet 20 0.30 1.7e-18 -2.6 -5.7 1.2e-08 0.54 0.97 0.02 FALSE
38 GTEx Heart Atrial Appendage CROCC 0.13 0.10 enet 11 0.13 1.5e-06 -4.1 -5.7 1.5e-08 0.59 0.40 0.52 FALSE
39 GTEx Heart Atrial Appendage MST1P2 0.20 0.09 lasso 4 0.09 6.7e-05 -5.1 5.5 3.9e-08 -0.65 0.04 0.92 FALSE
40 GTEx Heart Atrial Appendage RP11-108M9.5 0.26 0.10 lasso 12 0.12 5.5e-06 -4.6 -6.3 3.9e-10 0.68 0.12 0.78 FALSE
41 GTEx Liver MST1P2 0.20 0.14 lasso 4 0.10 7.6e-04 4.8 5.6 2.6e-08 -0.71 0.02 0.90 FALSE
42 GTEx Lung MFAP2 0.09 0.08 enet 19 0.06 1.3e-05 -5.5 6.2 8.0e-10 -0.72 0.02 0.98 FALSE
43 GTEx Lung MST1P2 0.20 0.10 enet 26 0.10 5.0e-08 4.9 5.9 4.6e-09 -0.60 0.05 0.95 FALSE
44 GTEx Lung RP4-798A10.7 0.11 0.05 lasso 4 0.02 1.0e-02 -5.3 -5.8 7.7e-09 0.58 0.02 0.94 FALSE
45 GTEx Muscle Skeletal RP11-108M9.4 0.26 0.09 enet 24 0.23 1.3e-22 -4.8 -5.2 2.5e-07 0.44 0.24 0.76 FALSE
46 GTEx Nerve Tibial SDHB 0.10 0.07 lasso 3 0.07 1.7e-05 -5.2 5.2 1.6e-07 -0.71 0.07 0.91 FALSE
47 GTEx Nerve Tibial MFAP2 0.09 0.06 lasso 3 0.07 9.7e-06 5.1 5.7 1.0e-08 -0.74 0.03 0.97 FALSE
48 GTEx Nerve Tibial MST1L 0.23 0.16 lasso 7 0.22 6.6e-16 -4.1 -5.3 1.2e-07 0.62 0.09 0.91 FALSE
49 GTEx Nerve Tibial RP11-108M9.5 0.41 0.12 lasso 12 0.24 2.2e-17 -5.3 -6.0 2.3e-09 0.50 0.10 0.90 FALSE
50 GTEx Ovary CROCC 0.22 0.05 lasso 4 0.02 1.2e-01 -4.6 -5.2 1.7e-07 0.62 0.07 0.37 FALSE
51 GTEx Skin Sun Exposed Lower leg MST1P2 0.24 0.00 enet 29 0.13 8.8e-11 4.9 5.9 4.6e-09 -0.55 0.06 0.93 FALSE
52 GTEx Skin Sun Exposed Lower leg MST1L 0.34 0.20 enet 37 0.25 5.6e-21 -4.1 -5.9 3.9e-09 0.62 0.56 0.43 FALSE
53 GTEx Skin Sun Exposed Lower leg NBPF1 0.14 0.04 lasso 7 0.05 2.9e-05 -4.8 -5.3 1.2e-07 0.62 0.29 0.70 FALSE
54 GTEx Stomach RP11-108M9.5 0.37 0.10 enet 20 0.30 8.9e-15 -4.8 -5.6 2.3e-08 0.58 0.08 0.92 FALSE
55 GTEx Stomach RP11-108M9.4 0.35 0.09 enet 20 0.23 2.1e-11 -2.6 -5.3 8.8e-08 0.49 0.42 0.55 FALSE
56 GTEx Testis CROCC 0.18 0.03 lasso 4 0.04 1.0e-02 4.8 -5.8 8.3e-09 0.70 0.06 0.48 FALSE
57 GTEx Testis SDHB 0.14 0.13 lasso 3 0.09 6.4e-05 -5.1 5.2 1.5e-07 -0.77 0.08 0.90 FALSE
58 GTEx Testis MST1P2 0.44 0.03 enet 33 0.25 2.8e-11 4.8 5.1 3.0e-07 -0.46 0.05 0.77 FALSE
59 GTEx Testis MST1L 0.45 0.20 enet 34 0.25 2.5e-11 -5.5 -5.4 5.2e-08 0.72 0.02 0.98 FALSE
60 GTEx Thyroid MST1P2 0.18 0.11 lasso 9 0.13 2.7e-10 4.9 6.2 7.2e-10 -0.67 0.04 0.95 FALSE
61 GTEx Thyroid RP11-108M9.5 0.28 0.06 enet 26 0.21 8.7e-16 -3.8 -5.6 2.6e-08 0.54 0.57 0.41 FALSE
62 GTEx Whole Blood MST1L 0.08 0.02 enet 12 0.04 6.3e-05 -4.1 -5.9 3.1e-09 0.73 0.03 0.96 FALSE
63 ROSMAP Brain Pre-frontal Cortex SDHB 0.04 0.04 lasso 2 0.03 5.4e-05 -5.2 5.2 1.5e-07 -0.74 0.09 0.89 FALSE
64 ROSMAP Brain Pre-frontal Cortex MST1P2 0.30 0.05 blup 251 0.23 2.0e-29 -5.5 5.5 4.5e-08 -0.49 0.01 0.99 FALSE
65 The Cancer Genome Atlas Bladder Urothelial Carcinoma CROCC 0.09 0.04 lasso 4 0.06 1.3e-05 -4.1 -5.4 5.6e-08 0.75 0.03 0.96 FALSE
66 The Cancer Genome Atlas Breast Invasive Carcinoma ATP13A2 0.05 0.00 enet 1 0.01 1.6e-02 -5.8 5.8 7.9e-09 -0.65 0.00 0.56 FALSE
67 The Cancer Genome Atlas Breast Invasive Carcinoma MFAP2 0.04 0.03 blup 38 0.03 1.1e-06 -4.8 5.1 2.9e-07 -0.61 0.06 0.94 FALSE
68 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MST1P9 0.11 0.11 blup 38 0.08 1.3e-04 -5.8 -6.1 1.3e-09 0.70 0.00 0.99 FALSE
69 The Cancer Genome Atlas Colon Adenocarcinoma MFAP2 0.12 0.06 blup 38 0.07 4.3e-05 -5.5 6.3 2.2e-10 -0.83 0.01 0.99 TRUE
70 The Cancer Genome Atlas Esophageal Carcinoma CROCC 0.17 0.05 lasso 4 0.09 7.7e-04 -4.8 -5.5 3.1e-08 0.72 0.03 0.80 FALSE
71 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATP13A2 0.05 0.08 enet 5 0.07 2.1e-08 -5.1 5.7 1.0e-08 -0.79 0.03 0.97 FALSE
72 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MFAP2 0.10 0.05 enet 21 0.07 5.7e-08 -4.6 5.7 1.2e-08 -0.70 0.16 0.84 FALSE
73 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MFAP2 0.17 0.22 enet 10 0.23 6.8e-26 -5.8 6.0 2.7e-09 -0.67 0.00 1.00 FALSE
74 The Cancer Genome Atlas Brain Lower Grade Glioma ATP13A2 0.05 0.05 lasso 3 0.07 2.6e-08 -4.6 5.2 1.7e-07 -0.60 0.10 0.89 FALSE
75 The Cancer Genome Atlas Brain Lower Grade Glioma MFAP2 0.02 0.02 lasso 1 0.02 2.4e-03 -5.3 5.3 8.9e-08 -0.51 0.03 0.61 FALSE
76 The Cancer Genome Atlas Brain Lower Grade Glioma MST1P9 0.15 0.13 enet 14 0.17 6.2e-19 -5.8 -5.9 4.0e-09 0.69 0.00 1.00 FALSE
77 The Cancer Genome Atlas Lung Adenocarcinoma ATP13A2 0.07 0.05 lasso 4 0.06 4.8e-07 -5.5 5.4 5.7e-08 -0.69 0.02 0.98 FALSE
78 The Cancer Genome Atlas Lung Adenocarcinoma MFAP2 0.04 0.03 blup 38 0.03 6.7e-05 -5.5 5.6 2.0e-08 -0.69 0.01 0.96 FALSE
79 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ATP13A2 0.06 0.04 blup 54 0.05 7.7e-07 -4.8 6.2 5.4e-10 -0.78 0.07 0.93 FALSE
80 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MFAP2 0.04 0.02 blup 38 0.03 1.5e-04 -4.8 5.8 4.8e-09 -0.80 0.02 0.94 FALSE
81 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MST1P9 0.04 0.02 lasso 5 0.02 1.0e-03 -5.5 -6.0 2.1e-09 0.82 0.01 0.94 FALSE
82 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MST1P9 0.08 0.05 blup 38 0.08 4.2e-06 4.9 -6.2 5.5e-10 0.75 0.02 0.96 FALSE
83 The Cancer Genome Atlas Pancreatic Adenocarcinoma ATP13A2 0.14 0.05 blup 54 0.08 2.5e-04 -5.3 5.8 5.9e-09 -0.66 0.02 0.83 FALSE
84 The Cancer Genome Atlas Prostate Adenocarcinoma MFAP2 0.06 0.04 blup 38 0.05 5.2e-06 5.1 5.5 3.0e-08 -0.78 0.04 0.96 FALSE
85 The Cancer Genome Atlas Prostate Adenocarcinoma MST1P9 0.13 0.09 lasso 6 0.11 3.3e-11 4.9 -5.5 3.9e-08 0.66 0.02 0.98 FALSE
86 The Cancer Genome Atlas Soft Tissue Sarcoma MST1P9 0.10 0.04 enet 11 0.05 3.4e-04 -4.1 -5.1 2.8e-07 0.61 0.02 0.66 FALSE
87 The Cancer Genome Atlas Soft Tissue Sarcoma SDHB 0.06 0.03 blup 99 0.02 2.1e-02 -5.5 5.7 1.1e-08 -0.85 0.02 0.68 FALSE