[Hub]/) : Traits : Impedance of arm (left) :

chr1:752,566-2,573,199

Best TWAS P=3.61e-13 · Best GWAS P=2.28e-13 conditioned to 0.233

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 6.1 -5.6 1.9e-08 -0.71 0.93 0.07 FALSE
2 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 1.8 5.6 1.8e-08 0.21 0.15 0.07 TRUE
3 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 6.4 6.5 5.8e-11 0.85 0.02 0.70 FALSE
4 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 7.2 -7.3 3.6e-13 -0.91 0.01 0.75 TRUE
5 GTEx Cells Transformed fibroblasts CDK11B 0.10 0.06 lasso 4 0.05 2.1e-04 -2.0 5.6 2.4e-08 0.85 0.03 0.90 FALSE
6 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 6.4 -6.4 1.3e-10 -0.83 0.65 0.35 FALSE
7 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 -5.9 6.7 2.8e-11 0.94 0.02 0.93 FALSE
8 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 6.4 6.6 5.3e-11 0.79 0.05 0.85 FALSE
9 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 6.7 -6.4 1.2e-10 -0.84 0.39 0.61 FALSE
10 GTEx Pituitary NADK 0.21 0.09 enet 15 0.07 9.5e-03 6.7 5.5 3.2e-08 0.67 0.03 0.55 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 -5.9 -6.3 2.4e-10 -0.92 0.03 0.97 FALSE
12 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 -6.8 -6.8 7.3e-12 -0.92 0.04 0.96 FALSE
13 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 4.0 -5.7 1.2e-08 -0.70 0.99 0.01 FALSE
14 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 5.7 5.7 1.6e-08 0.80 0.06 0.92 FALSE
15 ROSMAP Brain Pre-frontal Cortex SLC35E2 0.03 0.00 blup 291 0.01 1.4e-02 1.4 -5.3 1.4e-07 -0.73 0.03 0.68 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC35E2 0.03 0.03 blup 35 0.01 7.0e-02 7.1 6.2 5.7e-10 0.95 0.00 0.99 FALSE
17 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 6.5 -6.6 3.9e-11 -0.91 0.01 0.80 FALSE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC35E2 0.03 0.00 blup 34 0.01 5.3e-02 6.0 -5.8 8.1e-09 -0.82 0.02 0.48 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma SLC35E2 0.04 0.03 lasso 5 0.05 1.4e-06 6.0 -5.4 6.7e-08 -0.79 0.01 0.98 FALSE