Best TWAS P=2.49e-12 · Best GWAS P=5.1e-11 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DTX2P1-UPK3BP1-PMS2P11 | 0.18 | 0.09 | enet | 21 | 0.12 | 6.1e-15 | -5.5 | -7.0 | 2.5e-12 | 0.82 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Adipose Subcutaneous | RP11-467H10.2 | 0.12 | 0.00 | lasso | 6 | 0.01 | 2.1e-02 | -3.1 | -5.7 | 1.5e-08 | 0.05 | 0.13 | 0.05 | FALSE |
| 3 | GTEx | Brain Cerebellum | GSAP | 0.38 | 0.30 | lasso | 4 | 0.31 | 6.4e-10 | -4.5 | 5.2 | 2.1e-07 | -0.01 | 0.83 | 0.10 | TRUE |
| 4 | GTEx | Brain Frontal Cortex BA9 | GSAP | 0.38 | 0.22 | lasso | 6 | 0.21 | 3.0e-06 | -4.5 | 5.4 | 6.3e-08 | -0.13 | 0.14 | 0.20 | TRUE |
| 5 | GTEx | Skin Sun Exposed Lower leg | DTX2P1 | 0.16 | 0.03 | enet | 22 | 0.05 | 4.8e-05 | -6.6 | -6.4 | 1.5e-10 | 0.70 | 0.00 | 0.99 | FALSE |