TWAS
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Traits
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Traits
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Impedance of arm (left)
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chr7:75,913,086-77,744,459
Best TWAS P=2.49e-12 · Best GWAS P=5.1e-11 conditioned to NaN
76M
76.5M
77M
77.5M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
DTX2P1-UPK3BP1-PMS2P11
0.18
0.09
enet
21
0.12
6.1e-15
-5.5
-7.0
2.5e-12
0.82
0.00
1.00
TRUE
4
GTEx
Brain Frontal Cortex BA9
GSAP
0.38
0.22
lasso
6
0.21
3.0e-06
-4.5
5.4
6.3e-08
-0.13
0.14
0.20
TRUE
3
GTEx
Brain Cerebellum
GSAP
0.38
0.30
lasso
4
0.31
6.4e-10
-4.5
5.2
2.1e-07
-0.01
0.83
0.10
TRUE
5
GTEx
Skin Sun Exposed Lower leg
DTX2P1
0.16
0.03
enet
22
0.05
4.8e-05
-6.6
-6.4
1.5e-10
0.70
0.00
0.99
FALSE
2
GTEx
Adipose Subcutaneous
RP11-467H10.2
0.12
0.00
lasso
6
0.01
2.1e-02
-3.1
-5.7
1.5e-08
0.05
0.13
0.05
FALSE