Best TWAS P=2.88e-08 · Best GWAS P=3.65e-08 conditioned to 0.0691
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | TM2D2 | 0.07 | 0.07 | lasso | 3 | 0.06 | 3.4e-06 | -5.5 | 5.5 | 4.7e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Thyroid | RP11-90P5.2 | 0.09 | 0.00 | enet | 12 | 0.01 | 1.1e-01 | 4.2 | -5.2 | 2.4e-07 | 0.05 | 0.04 | 0.74 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TM2D2 | 0.06 | 0.07 | lasso | 6 | 0.08 | 2.9e-09 | -4.7 | 5.2 | 1.8e-07 | -0.93 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | TM2D2 | 0.15 | 0.08 | lasso | 2 | 0.08 | 1.5e-08 | 4.3 | 5.5 | 2.9e-08 | -0.72 | 0.29 | 0.68 | TRUE |