Best TWAS P=1.05e-08 · Best GWAS P=1.95e-08 conditioned to 0.162
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | RPS20 | 0.24 | 0.20 | lasso | 6 | 0.23 | 3.4e-29 | 5.6 | 5.3 | 1.2e-07 | 0.94 | 0.00 | 1.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP11-446E9.1 | 0.23 | 0.32 | lasso | 7 | 0.34 | 2.0e-45 | 4.8 | -5.3 | 1.0e-07 | -0.97 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RPS20 | 0.33 | 0.07 | enet | 8 | 0.07 | 1.7e-08 | 5.6 | 5.7 | 1.0e-08 | 0.86 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RPS20 | 0.04 | 0.03 | lasso | 3 | 0.04 | 1.3e-04 | 5.6 | 5.7 | 1.5e-08 | 0.98 | 0.00 | 0.97 | FALSE |