TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (left)
:
←
→
chr8:143,652,160-146,293,414
Best TWAS P=3.65e-10 · Best GWAS P=1.07e-11 conditioned to 0.085
143.5M
144M
144.5M
145M
145.5M
146M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Skin Not Sun Exposed Suprapubic
GS1-393G12.12
0.09
0.05
lasso
4
0.03
9.8e-03
6.1
6.3
3.6e-10
0.83
0.01
0.85
TRUE
4
GTEx
Testis
GLI4
0.14
0.03
enet
11
0.10
2.2e-05
-4.6
-5.5
4.8e-08
-0.12
0.02
0.94
TRUE
1
GTEx
Brain Cerebellar Hemisphere
MROH1
0.22
0.20
lasso
4
0.15
1.1e-04
6.1
6.2
5.2e-10
0.86
0.01
0.93
FALSE
2
GTEx
Brain Cerebellum
GPT
0.18
0.04
enet
18
0.07
4.2e-03
-3.9
-5.7
1.1e-08
-0.39
0.05
0.28
FALSE
5
GTEx
Thyroid
BOP1
0.19
0.10
enet
12
0.15
8.8e-12
6.8
5.4
5.3e-08
0.91
0.00
1.00
FALSE