Best TWAS P=3.65e-10 · Best GWAS P=1.07e-11 conditioned to 0.085
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | MROH1 | 0.22 | 0.20 | lasso | 4 | 0.15 | 1.1e-04 | 6.1 | 6.2 | 5.2e-10 | 0.86 | 0.01 | 0.93 | FALSE |
| 2 | GTEx | Brain Cerebellum | GPT | 0.18 | 0.04 | enet | 18 | 0.07 | 4.2e-03 | -3.9 | -5.7 | 1.1e-08 | -0.39 | 0.05 | 0.28 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | GS1-393G12.12 | 0.09 | 0.05 | lasso | 4 | 0.03 | 9.8e-03 | 6.1 | 6.3 | 3.6e-10 | 0.83 | 0.01 | 0.85 | TRUE |
| 4 | GTEx | Testis | GLI4 | 0.14 | 0.03 | enet | 11 | 0.10 | 2.2e-05 | -4.6 | -5.5 | 4.8e-08 | -0.12 | 0.02 | 0.94 | TRUE |
| 5 | GTEx | Thyroid | BOP1 | 0.19 | 0.10 | enet | 12 | 0.15 | 8.8e-12 | 6.8 | 5.4 | 5.3e-08 | 0.91 | 0.00 | 1.00 | FALSE |