Best TWAS P=1.11e-15 · Best GWAS P=1.27e-19 conditioned to 2.13e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ADAMTS14 | 0.28 | 0.24 | bslmm | 733 | 0.35 | 7.9e-44 | -3.3 | 7.5 | 5.0e-14 | 0.81 | 0.03 | 0.97 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ADAMTS14 | 0.38 | 0.35 | bslmm | 710 | 0.47 | 3.9e-67 | 9.1 | 8.0 | 1.1e-15 | 0.87 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ADAMTS14 | 0.05 | 0.03 | enet | 17 | 0.03 | 3.4e-07 | -3.6 | 6.0 | 1.7e-09 | 0.72 | 0.08 | 0.92 | FALSE |