TWAS
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Traits
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Traits
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Impedance of arm (left)
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chr10:71,736,472-73,217,461
Best TWAS P=1.11e-15 · Best GWAS P=1.27e-19 conditioned to 2.13e-05
71.8M
72M
72.2M
72.4M
72.6M
72.8M
73M
73.2M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
ADAMTS14
0.38
0.35
bslmm
710
0.47
3.9e-67
9.1
8.0
1.1e-15
0.87
0.00
1.00
TRUE
1
CommonMind
Brain Pre-frontal Cortex
ADAMTS14
0.28
0.24
bslmm
733
0.35
7.9e-44
-3.3
7.5
5.0e-14
0.81
0.03
0.97
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
ADAMTS14
0.05
0.03
enet
17
0.03
3.4e-07
-3.6
6.0
1.7e-09
0.72
0.08
0.92
FALSE