[Hub]/) : Traits : Impedance of arm (left) :

chr10:99,204,526-100,718,107

Best TWAS P=1.36e-13 · Best GWAS P=1.37e-14 conditioned to 7.73e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Muscularis LOXL4 0.16 0.16 lasso 3 0.15 2.4e-09 -7.1 7.2 6.2e-13 0.49 0.11 0.89 FALSE
2 GTEx Nerve Tibial R3HCC1L 0.06 0.07 enet 8 0.05 1.1e-04 5.6 6.6 3.8e-11 0.87 0.02 0.97 FALSE
3 GTEx Skin Sun Exposed Lower leg R3HCC1L 0.10 0.05 enet 14 0.05 3.4e-05 -6.2 7.2 7.6e-13 0.68 0.10 0.90 FALSE
4 GTEx Testis LOXL4 0.48 0.47 enet 8 0.46 1.0e-22 -7.1 7.2 6.8e-13 0.48 0.14 0.86 FALSE
5 ROSMAP Brain Pre-frontal Cortex R3HCC1L 0.03 0.04 lasso 3 0.02 1.1e-03 -7.0 6.8 9.8e-12 0.46 0.12 0.86 FALSE
6 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LOXL4 0.08 0.00 blup 51 0.02 9.4e-03 5.0 7.4 1.4e-13 0.62 0.01 0.43 TRUE
7 The Cancer Genome Atlas Prostate Adenocarcinoma LOXL4 0.09 0.05 enet 12 0.05 3.0e-06 -6.0 7.3 2.6e-13 0.42 0.14 0.82 FALSE