[Hub]/) : Traits : Impedance of arm (left) :

chr10:101,975,269-103,362,569

Best TWAS P=3.13e-11 · Best GWAS P=4.36e-12 conditioned to 1.29e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-179B2.2 0.15 0.08 lasso 6 0.08 3.2e-07 -4.8 -5.5 3.6e-08 0.02 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum RP11-179B2.2 0.13 0.02 lasso 3 0.03 6.5e-03 -6.6 -6.3 2.7e-10 0.02 0.01 0.99 FALSE
3 GTEx Artery Aorta RP11-179B2.2 0.16 0.11 lasso 2 0.09 7.6e-06 -6.6 -6.3 3.6e-10 0.02 0.00 0.99 FALSE
4 GTEx Artery Tibial RP11-179B2.2 0.11 0.09 lasso 4 0.08 8.8e-07 -6.6 -6.6 4.1e-11 0.03 0.00 1.00 FALSE
5 GTEx Brain Cerebellum RP11-179B2.2 0.37 0.21 lasso 4 0.20 1.4e-06 -6.7 -6.5 9.8e-11 0.02 0.00 0.99 FALSE
6 GTEx Brain Frontal Cortex BA9 RP11-179B2.2 0.22 0.15 lasso 2 0.11 7.2e-04 -6.7 -6.3 2.6e-10 0.01 0.01 0.96 FALSE
7 GTEx Breast Mammary Tissue RP11-179B2.2 0.11 0.09 lasso 2 0.07 1.8e-04 -6.6 -5.9 3.8e-09 0.02 0.01 0.99 FALSE
8 GTEx Breast Mammary Tissue (Male) RP11-179B2.2 0.16 -0.01 enet 4 -0.01 7.1e-01 5.4 -5.4 7.0e-08 0.07 0.03 0.48 FALSE
9 GTEx Esophagus Muscularis RP11-179B2.2 0.15 0.16 lasso 3 0.16 8.1e-10 -6.6 -6.6 3.4e-11 0.03 0.01 0.99 FALSE
10 GTEx Heart Left Ventricle RP11-179B2.2 0.15 0.18 enet 2 0.14 4.8e-08 -6.7 -6.6 3.1e-11 0.02 0.00 1.00 TRUE
11 GTEx Lung RP11-179B2.2 0.18 0.12 lasso 3 0.12 1.7e-09 -6.7 -6.3 3.1e-10 0.02 0.00 1.00 FALSE
12 GTEx Nerve Tibial RP11-179B2.2 0.15 0.08 lasso 2 0.12 6.4e-09 -6.6 -5.4 7.3e-08 0.01 0.01 0.99 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RP11-179B2.2 0.27 0.15 enet 36 0.15 2.0e-08 -6.7 -6.1 9.5e-10 0.00 0.00 1.00 FALSE
14 GTEx Thyroid RP11-179B2.2 0.18 0.12 lasso 7 0.11 8.3e-09 -4.8 -5.3 1.4e-07 0.02 0.03 0.97 FALSE
15 The Cancer Genome Atlas Colon Adenocarcinoma MRPL43 0.07 0.02 blup 52 0.00 1.7e-01 -6.4 5.9 3.8e-09 -0.03 0.01 0.86 FALSE