Best TWAS P=8.58e-13 · Best GWAS P=2.46e-11 conditioned to 0.000677
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | TRIM8 | 0.34 | -0.01 | enet | 25 | 0.07 | 0.00471 | 2.2 | 6.3 | 2.7e-10 | 0.37 | 0.06 | 0.41 | TRUE |
| 2 | GTEx | Liver | ACTR1A | 0.15 | 0.00 | lasso | 10 | 0.00 | 0.46000 | 6.0 | 7.2 | 8.6e-13 | 0.36 | 0.07 | 0.18 | TRUE |
| 3 | GTEx | Thyroid | OBFC1 | 0.09 | 0.00 | enet | 15 | 0.01 | 0.10600 | 4.9 | -5.5 | 3.0e-08 | 0.03 | 0.00 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TMEM180 | 0.06 | 0.03 | lasso | 5 | 0.03 | 0.00037 | -5.0 | -5.6 | 2.1e-08 | -0.10 | 0.00 | 0.98 | FALSE |