TWAS
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Traits
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Traits
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Impedance of arm (left)
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chr10:103,550,604-106,371,784
Best TWAS P=8.58e-13 · Best GWAS P=2.46e-11 conditioned to 0.000677
103.5M
104M
104.5M
105M
105.5M
106M
106.5M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Liver
ACTR1A
0.15
0.00
lasso
10
0.00
0.46000
6.0
7.2
8.6e-13
0.36
0.07
0.18
TRUE
1
GTEx
Brain Cerebellum
TRIM8
0.34
-0.01
enet
25
0.07
0.00471
2.2
6.3
2.7e-10
0.37
0.06
0.41
TRUE
3
GTEx
Thyroid
OBFC1
0.09
0.00
enet
15
0.01
0.10600
4.9
-5.5
3.0e-08
0.03
0.00
0.96
TRUE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
TMEM180
0.06
0.03
lasso
5
0.03
0.00037
-5.0
-5.6
2.1e-08
-0.10
0.00
0.98
FALSE