Best TWAS P=7.31e-09 · Best GWAS P=2.41e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAN1 | 0.09 | 0.12 | lasso | 4 | 0.12 | 3.9e-14 | -5.3 | -5.8 | 7.3e-09 | 0.97 | 0.01 | 0.99 | TRUE |
2 | GTEx | Adipose Subcutaneous | FAN1 | 0.10 | 0.04 | lasso | 6 | 0.08 | 4.4e-07 | -4.8 | -5.8 | 8.1e-09 | 0.73 | 0.12 | 0.85 | FALSE |