[Hub]/) : Traits : Impedance of arm (left) : ← →

chr15:44,959,112-46,410,543

Best TWAS P=1.91e-09 · Best GWAS P=2.27e-09 conditioned to 0.303

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
35	YFS	Blood	GATM	0.03	0.05	lasso	19	0.06	4.1e-19	-5.8	6.0	1.9e-09	-0.94	0.01	0.99	TRUE
47	The Cancer Genome Atlas	Lung Adenocarcinoma	GATM	0.04	0.01	blup	41	0.02	1.8e-03	-5.7	6.0	2.0e-09	-0.97	0.01	0.85	FALSE
29	GTEx	Thyroid	GATM	0.14	0.13	lasso	5	0.17	8.4e-13	-5.2	5.9	3.9e-09	-0.91	0.04	0.96	FALSE
48	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	GATM	0.02	0.01	blup	41	0.02	5.1e-03	-5.2	5.9	4.2e-09	-0.88	0.02	0.74	FALSE
53	The Cancer Genome Atlas	Prostate Adenocarcinoma	GATM	0.03	0.03	blup	41	0.04	7.3e-05	-5.2	5.8	5.4e-09	-0.86	0.07	0.91	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GATM	0.02	0.01	blup	41	0.01	1.0e-02	-5.1	5.8	8.5e-09	-0.88	0.04	0.78	FALSE
40	The Cancer Genome Atlas	Colon Adenocarcinoma	GATM	0.35	0.18	blup	41	0.18	2.4e-10	-5.8	5.7	1.2e-08	-0.95	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SPATA5L1	0.08	0.01	blup	33	0.03	1.2e-02	-5.0	-5.6	2.2e-08	0.89	0.01	0.67	FALSE
2	GTEx	Adipose Subcutaneous	SPATA5L1	0.15	0.21	enet	19	0.21	2.4e-17	-5.2	-5.6	2.4e-08	0.82	0.30	0.70	FALSE
51	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	GATM	0.09	0.10	lasso	1	0.09	1.6e-04	-5.5	5.5	3.0e-08	-0.75	0.14	0.55	FALSE
15	GTEx	Esophagus Mucosa	GATM	0.10	0.04	enet	20	0.10	5.7e-07	-4.9	5.5	3.2e-08	-0.89	0.06	0.94	FALSE
57	The Cancer Genome Atlas	Thyroid Carcinoma	GATM	0.03	0.03	blup	41	0.02	1.7e-03	-5.2	5.5	3.7e-08	-0.80	0.11	0.63	FALSE
14	GTEx	Esophagus Mucosa	SPATA5L1	0.17	0.14	enet	21	0.15	5.0e-10	-5.2	-5.4	5.3e-08	0.75	0.30	0.70	FALSE
25	GTEx	Skin Sun Exposed Lower leg	GATM	0.11	0.11	lasso	7	0.11	3.5e-09	-5.2	5.4	8.4e-08	-0.72	0.31	0.69	FALSE
33	NTR	Blood	GATM	0.03	0.02	lasso	7	0.02	8.3e-08	-5.2	5.4	8.5e-08	-0.76	0.25	0.75	FALSE
3	GTEx	Adipose Visceral Omentum	SPATA5L1	0.15	0.14	enet	21	0.13	3.0e-07	-5.2	-5.3	1.0e-07	0.76	0.30	0.70	FALSE
17	GTEx	Heart Atrial Appendage	SPATA5L1	0.15	0.10	lasso	5	0.06	1.4e-03	-5.2	-5.3	1.1e-07	0.72	0.18	0.71	FALSE
18	GTEx	Heart Left Ventricle	SPATA5L1	0.10	0.09	enet	9	0.06	4.3e-04	-5.2	-5.3	1.3e-07	0.72	0.27	0.66	FALSE
56	The Cancer Genome Atlas	Stomach Adenocarcinoma	SPATA5L1	0.05	0.06	blup	33	0.06	2.9e-05	-5.2	-5.3	1.3e-07	0.77	0.09	0.88	FALSE
20	GTEx	Muscle Skeletal	SPATA5L1	0.10	0.12	lasso	6	0.10	1.9e-10	-5.2	-5.3	1.4e-07	0.73	0.31	0.68	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SPATA5L1	0.12	0.24	lasso	7	0.24	6.8e-29	-5.2	-5.2	1.5e-07	0.72	0.31	0.69	FALSE
31	METSIM	Adipose	GATM	0.11	0.22	lasso	12	0.22	6.7e-33	-5.1	5.3	1.5e-07	-0.75	0.30	0.70	FALSE
5	GTEx	Artery Aorta	SPATA5L1	0.24	0.30	enet	13	0.29	2.1e-16	-5.2	-5.2	1.7e-07	0.73	0.30	0.70	FALSE
6	GTEx	Artery Coronary	SPATA5L1	0.26	0.30	lasso	3	0.28	3.8e-10	-5.2	-5.2	1.7e-07	0.72	0.30	0.70	FALSE
16	GTEx	Esophagus Muscularis	SPATA5L1	0.24	0.24	lasso	4	0.24	4.7e-15	-5.2	-5.2	1.7e-07	0.74	0.30	0.70	FALSE
24	GTEx	Skin Sun Exposed Lower leg	SPATA5L1	0.07	0.10	lasso	4	0.10	2.4e-08	-5.2	-5.2	1.7e-07	0.72	0.30	0.70	FALSE
26	GTEx	Small Intestine Terminal Ileum	SPATA5L1	0.23	0.26	lasso	1	0.26	1.6e-06	-5.2	-5.2	1.7e-07	0.72	0.19	0.48	FALSE
27	GTEx	Spleen	SPATA5L1	0.27	0.19	lasso	1	0.15	9.8e-05	-5.2	-5.2	1.7e-07	0.72	0.18	0.43	FALSE
44	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SPATA5L1	0.12	0.17	lasso	7	0.15	3.7e-09	-5.2	-5.2	1.7e-07	0.72	0.19	0.81	FALSE
10	GTEx	Cells Transformed fibroblasts	SPATA5L1	0.30	0.41	lasso	5	0.41	9.7e-33	-5.2	-5.2	1.8e-07	0.73	0.30	0.70	FALSE
23	GTEx	Nerve Tibial	GATM	0.07	0.04	lasso	2	0.08	1.9e-06	2.2	5.2	1.8e-07	-0.49	0.23	0.54	FALSE
37	The Cancer Genome Atlas	Breast Invasive Carcinoma	GATM	0.02	0.03	lasso	3	0.02	7.3e-06	-5.2	5.2	1.8e-07	-0.73	0.29	0.70	FALSE
41	The Cancer Genome Atlas	Glioblastoma Multiforme	SPATA5L1	0.13	0.10	enet	8	0.06	5.0e-03	-5.2	-5.2	1.8e-07	0.73	0.07	0.39	FALSE
49	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SPATA5L1	0.06	0.09	enet	6	0.08	5.2e-06	-5.2	-5.2	1.8e-07	0.73	0.14	0.85	FALSE
55	The Cancer Genome Atlas	Soft Tissue Sarcoma	SPATA5L1	0.05	0.07	enet	6	0.05	7.2e-04	-5.1	-5.2	1.8e-07	0.73	0.15	0.78	FALSE
22	GTEx	Nerve Tibial	SPATA5L1	0.20	0.33	lasso	10	0.33	5.3e-24	-5.2	-5.2	1.9e-07	0.72	0.30	0.70	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	SPATA5L1	0.17	0.18	enet	18	0.18	2.1e-06	-5.2	-5.2	2.0e-07	0.70	0.27	0.62	FALSE
11	GTEx	Colon Sigmoid	SPATA5L1	0.17	0.21	lasso	3	0.18	6.4e-07	-5.2	-5.2	2.0e-07	0.72	0.29	0.70	FALSE
46	The Cancer Genome Atlas	Brain Lower Grade Glioma	SPATA5L1	0.10	0.18	enet	15	0.18	2.7e-20	-5.2	-5.2	2.0e-07	0.73	0.19	0.81	FALSE
50	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SPATA5L1	0.13	0.21	lasso	7	0.20	1.1e-08	-5.2	-5.2	2.0e-07	0.73	0.18	0.82	FALSE
52	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SPATA5L1	0.12	0.11	enet	14	0.11	3.1e-05	-5.2	-5.2	2.0e-07	0.73	0.12	0.76	FALSE
19	GTEx	Lung	GATM	0.04	0.04	lasso	2	0.02	8.2e-03	-5.2	5.2	2.1e-07	-0.89	0.05	0.82	FALSE
34	NTR	Blood	SPATA5L1	0.05	0.08	lasso	11	0.08	1.6e-25	-5.2	-5.2	2.1e-07	0.76	0.34	0.66	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	SPATA5L1	0.18	0.20	lasso	10	0.14	8.2e-06	-5.2	-5.2	2.2e-07	0.73	0.31	0.67	FALSE
43	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC28A2	0.03	0.04	blup	55	0.03	7.3e-03	-5.3	5.2	2.2e-07	-0.89	0.03	0.58	FALSE
45	The Cancer Genome Atlas	Brain Lower Grade Glioma	GATM	0.02	0.02	enet	8	0.02	1.8e-03	-5.2	5.2	2.2e-07	-0.73	0.19	0.55	FALSE
12	GTEx	Colon Transverse	SPATA5L1	0.19	0.16	lasso	2	0.14	2.7e-07	-5.2	-5.2	2.3e-07	0.73	0.30	0.69	FALSE
21	GTEx	Muscle Skeletal	GATM	0.13	0.10	lasso	6	0.11	9.3e-11	-5.2	-5.2	2.3e-07	0.72	0.30	0.70	FALSE
32	METSIM	Adipose	SPATA5L1	0.16	0.26	lasso	20	0.25	2.0e-37	-5.2	-5.2	2.3e-07	0.73	0.31	0.69	FALSE
7	GTEx	Artery Tibial	SPATA5L1	0.21	0.21	enet	20	0.22	4.6e-17	-5.2	-5.2	2.4e-07	0.68	0.29	0.71	FALSE
54	The Cancer Genome Atlas	Prostate Adenocarcinoma	SPATA5L1	0.14	0.21	lasso	2	0.21	1.5e-21	-5.2	-5.2	2.5e-07	0.73	0.20	0.80	FALSE
30	GTEx	Whole Blood	SPATA5L1	0.24	0.26	lasso	5	0.26	2.4e-24	-5.2	-5.2	2.6e-07	0.71	0.29	0.71	FALSE
28	GTEx	Thyroid	SPATA5L1	0.19	0.23	lasso	6	0.23	1.6e-17	-5.2	-5.2	2.7e-07	0.71	0.31	0.69	FALSE
36	YFS	Blood	SPATA5L1	0.21	0.45	lasso	16	0.45	7.5e-166	-5.1	-5.2	2.7e-07	0.74	0.36	0.64	FALSE
4	GTEx	Adrenal Gland	SPATA5L1	0.16	0.21	lasso	3	0.18	6.3e-07	-5.0	-5.1	2.8e-07	0.71	0.30	0.67	FALSE
8	GTEx	Breast Mammary Tissue	SPATA5L1	0.31	0.17	lasso	7	0.18	2.4e-09	-5.2	-5.1	2.8e-07	0.70	0.30	0.70	FALSE
38	The Cancer Genome Atlas	Breast Invasive Carcinoma	SPATA5L1	0.05	0.08	lasso	2	0.07	7.6e-15	-5.1	-5.1	2.8e-07	0.73	0.20	0.80	FALSE