[Hub]/) : Traits : Impedance of arm (left) : ← →

chr1:172,881,827-175,663,031

Best TWAS P=1.23e-10 · Best GWAS P=8.7e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	METSIM	Adipose	SERPINC1	0.10	0.09	bslmm	271	0.09	1.2e-13	-6.19	-6.4	1.2e-10	0.95	0.04	0.96	TRUE
5	GTEx	Breast Mammary Tissue (Male)	RC3H1	0.07	0.11	enet	3	0.07	9.9e-03	-6.37	6.4	1.7e-10	-1.00	0.03	0.57	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	SERPINC1	0.14	0.09	blup	47	0.09	1.2e-17	-6.19	-6.4	2.0e-10	0.93	0.01	0.99	FALSE
7	GTEx	Esophagus Muscularis	RC3H1	0.10	0.08	lasso	13	0.06	1.2e-04	-6.28	6.3	3.3e-10	-0.98	0.03	0.97	FALSE
2	GTEx	Adrenal Gland	RC3H1	0.12	0.06	lasso	2	0.06	3.2e-03	-6.17	6.3	3.9e-10	-0.98	0.04	0.77	FALSE
3	GTEx	Artery Tibial	RC3H1	0.09	0.07	lasso	2	0.07	2.6e-06	-6.17	6.2	4.8e-10	-0.98	0.03	0.96	FALSE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	SERPINC1	0.08	0.04	blup	48	0.05	5.8e-07	-6.29	-6.2	7.5e-10	0.84	0.01	0.99	FALSE
8	GTEx	Nerve Tibial	RC3H1	0.09	0.06	enet	7	0.07	7.0e-06	-6.12	6.2	8.0e-10	-0.97	0.05	0.95	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SERPINC1	0.32	0.11	enet	10	0.12	1.6e-05	-6.29	-6.1	1.4e-09	0.84	0.01	0.98	FALSE
6	GTEx	Breast Mammary Tissue (Female)	RABGAP1L	0.19	0.00	lasso	3	0.01	2.0e-01	-6.28	-6.0	1.8e-09	0.92	0.06	0.41	FALSE
4	GTEx	Breast Mammary Tissue	RC3H1	0.17	0.05	enet	30	0.05	2.2e-03	-6.03	6.0	2.0e-09	-0.77	0.04	0.93	FALSE
31	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MRPS14	0.12	0.01	lasso	4	0.01	1.1e-01	-5.71	-6.0	2.0e-09	0.94	0.00	0.94	FALSE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SERPINC1	0.31	0.07	lasso	2	0.05	6.8e-04	-5.99	-5.9	3.0e-09	0.93	0.02	0.97	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SERPINC1	0.13	0.03	blup	47	0.03	1.7e-04	-6.12	-5.9	3.1e-09	0.93	0.01	0.98	FALSE
33	The Cancer Genome Atlas	Prostate Adenocarcinoma	SERPINC1	0.08	0.01	blup	47	0.03	1.6e-04	-6.03	-5.9	3.3e-09	0.77	0.01	0.86	FALSE
34	The Cancer Genome Atlas	Soft Tissue Sarcoma	SERPINC1	0.12	0.08	lasso	5	0.08	2.4e-05	-6.12	-5.9	3.4e-09	0.91	0.01	0.97	FALSE
11	GTEx	Testis	RC3H1	0.13	0.03	enet	24	0.06	8.0e-04	-6.27	5.9	4.1e-09	-0.88	0.04	0.93	FALSE
35	The Cancer Genome Atlas	Stomach Adenocarcinoma	SERPINC1	0.09	0.04	lasso	5	0.04	5.8e-04	-6.29	-5.9	4.4e-09	0.96	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CACYBP	0.11	0.05	lasso	2	0.04	9.6e-04	-5.71	-5.8	7.7e-09	0.95	0.00	0.98	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	RABGAP1L	0.07	0.01	lasso	3	0.01	1.2e-02	-5.71	-5.7	9.2e-09	0.97	0.03	0.94	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MRPS14	0.12	0.05	lasso	3	0.03	6.5e-04	-5.71	-5.7	1.0e-08	0.95	0.00	0.99	FALSE
25	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RC3H1	0.15	0.00	blup	58	0.03	1.8e-02	-6.12	-5.7	1.4e-08	0.89	0.02	0.55	FALSE
36	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RC3H1	0.13	-0.01	blup	58	0.01	1.4e-01	-6.17	-5.7	1.6e-08	0.80	0.01	0.24	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	SERPINC1	0.06	0.02	blup	48	0.02	1.7e-03	-6.19	-5.6	1.7e-08	0.92	0.01	0.96	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	SERPINC1	0.10	0.06	blup	47	0.06	1.8e-04	-5.09	-5.5	4.1e-08	0.76	0.02	0.81	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	CACYBP	0.11	0.04	lasso	3	0.03	9.3e-08	-5.31	-5.4	6.5e-08	0.96	0.00	1.00	FALSE
29	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CACYBP	0.06	0.02	lasso	2	0.01	3.3e-02	-5.71	-5.4	6.5e-08	0.94	0.00	0.93	FALSE
10	GTEx	Pancreas	RC3H1	0.09	0.02	enet	6	0.01	1.6e-01	-6.32	5.4	6.9e-08	-0.96	0.03	0.63	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	CACYBP	0.19	0.00	lasso	2	0.00	7.2e-01	-5.31	-5.4	7.3e-08	0.96	0.00	0.98	FALSE
19	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DARS2	0.14	0.00	blup	37	0.01	8.2e-02	-6.12	-5.4	7.5e-08	0.75	0.00	0.43	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	MRPS14	0.13	0.06	lasso	4	0.06	4.0e-12	-5.31	-5.4	7.8e-08	0.95	0.00	1.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ANKRD45	0.11	0.11	bslmm	303	0.12	7.5e-14	-4.97	5.4	8.0e-08	-0.82	0.94	0.06	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	SERPINC1	0.14	0.05	lasso	2	0.06	6.6e-07	-6.19	-5.2	1.9e-07	0.91	0.01	0.99	FALSE
9	GTEx	Ovary	RC3H1	0.32	0.03	lasso	8	0.07	8.6e-03	-6.25	5.2	2.1e-07	-0.82	0.03	0.54	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SERPINC1	0.11	0.06	blup	47	0.05	3.7e-06	-6.19	-5.2	2.2e-07	0.88	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	ZBTB37	0.07	0.00	blup	47	0.03	2.2e-04	2.44	-5.1	2.9e-07	0.66	0.02	0.54	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	DARS2	0.04	0.00	blup	36	0.01	5.9e-04	0.56	-5.1	3.0e-07	0.66	0.01	0.45	FALSE