Best TWAS P=2.34e-14 · Best GWAS P=6.29e-14 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PIAS1 | 0.26 | 0.12 | enet | 22 | 0.10 | 3.4e-06 | 5.6 | -5.8 | 4.8e-09 | -0.02 | 0.66 | 0.31 | FALSE |
| 2 | GTEx | Artery Tibial | PIAS1 | 0.14 | 0.02 | enet | 26 | 0.08 | 1.6e-06 | 3.6 | -5.9 | 2.8e-09 | -0.03 | 0.66 | 0.24 | FALSE |
| 3 | GTEx | Brain Putamen basal ganglia | DIS3L | 0.37 | 0.01 | lasso | 4 | 0.02 | 1.4e-01 | -4.2 | -5.3 | 9.0e-08 | -0.01 | 0.05 | 0.12 | TRUE |
| 4 | GTEx | Colon Transverse | IQCH-AS1 | 0.24 | 0.01 | enet | 31 | 0.08 | 1.5e-04 | 6.6 | 5.8 | 6.6e-09 | 0.19 | 0.38 | 0.10 | FALSE |
| 5 | GTEx | Muscle Skeletal | SMAD3 | 0.13 | 0.10 | enet | 8 | 0.10 | 4.2e-10 | 7.4 | 7.6 | 2.3e-14 | 0.97 | 0.00 | 1.00 | TRUE |
| 6 | GTEx | Nerve Tibial | PIAS1 | 0.20 | 0.10 | lasso | 8 | 0.14 | 3.0e-10 | 5.6 | -6.3 | 3.7e-10 | -0.07 | 0.64 | 0.36 | TRUE |
| 7 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LBXCOR1 | 0.07 | 0.03 | blup | 57 | 0.03 | 6.3e-03 | 6.1 | -6.3 | 3.9e-10 | 0.02 | 0.02 | 0.62 | TRUE |