[Hub]/) : Traits : Impedance of arm (left) :

chr15:73,524,629-75,159,433

Best TWAS P=1.69e-14 · Best GWAS P=1.12e-18 conditioned to 7.82e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts LOXL1-AS1 0.28 0.09 lasso 6 0.17 1.7e-12 4.0 6.5 1.0e-10 -0.64 0.99 0.01 FALSE
2 GTEx Skin Sun Exposed Lower leg ISLR 0.08 0.00 enet 14 0.03 2.8e-03 3.8 6.9 4.0e-12 -0.12 0.15 0.07 FALSE
3 GTEx Testis LOXL1-AS1 0.36 0.15 lasso 10 0.13 2.4e-06 -7.0 -7.7 1.7e-14 0.60 0.51 0.08 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma ISLR2 0.02 0.02 lasso 2 0.01 5.4e-04 -7.5 -7.5 9.4e-14 0.17 0.00 0.99 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma ISLR 0.02 0.02 lasso 2 0.01 6.2e-04 -7.4 7.5 5.8e-14 -0.15 0.01 0.94 TRUE
6 The Cancer Genome Atlas Breast Invasive Carcinoma LOC283731 0.02 0.01 blup 15 0.01 1.9e-03 -7.5 -6.8 1.4e-11 0.20 0.00 0.88 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma STRA6 0.02 0.02 lasso 2 0.02 4.5e-05 -6.6 6.5 1.0e-10 -0.09 0.09 0.50 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC283731 0.02 0.03 lasso 2 0.02 7.7e-04 -7.5 -7.5 7.3e-14 0.17 0.00 0.97 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma CCDC33 0.05 0.02 blup 93 0.04 4.0e-05 2.1 5.8 7.2e-09 -0.12 0.27 0.65 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ISLR2 0.06 0.07 lasso 2 0.06 3.9e-07 -7.5 -7.5 7.3e-14 0.17 0.00 1.00 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma LOC283731 0.02 0.03 lasso 3 0.02 1.5e-03 -7.3 -7.4 1.3e-13 0.17 0.00 0.95 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ISLR2 0.04 0.05 lasso 2 0.04 6.5e-05 -7.5 -7.5 7.0e-14 0.16 0.00 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma LOC283731 0.04 0.06 lasso 1 0.05 4.8e-06 -7.3 -7.3 2.1e-13 0.16 0.00 1.00 FALSE