TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (left)
:
←
→
chr17:1,588,930-3,000,009
Best TWAS P=5.22e-11 · Best GWAS P=2.1e-09 conditioned to 1.67e-11
1.6M
1.8M
2M
2.2M
2.4M
2.6M
2.8M
3M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
SMG6
0.03
0.01
blup
144
0.01
4.8e-03
-4.5
-6.6
5.2e-11
-0.07
0.08
0.64
TRUE
3
The Cancer Genome Atlas
Colon Adenocarcinoma
PAFAH1B1
0.11
0.00
blup
61
0.04
3.6e-03
-1.6
6.5
6.4e-11
0.04
0.00
0.04
TRUE
4
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SMG6
0.08
0.05
blup
144
0.07
1.3e-04
-5.2
-6.5
7.1e-11
-0.07
0.05
0.91
FALSE
1
ROSMAP
Brain Pre-frontal Cortex
MNT
0.09
0.04
lasso
5
0.06
9.5e-09
5.2
-5.5
4.9e-08
-0.07
0.15
0.85
FALSE