Best TWAS P=5.22e-11 · Best GWAS P=2.1e-09 conditioned to 1.67e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | MNT | 0.09 | 0.04 | lasso | 5 | 0.06 | 9.5e-09 | 5.2 | -5.5 | 4.9e-08 | -0.07 | 0.15 | 0.85 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 4.8e-03 | -4.5 | -6.6 | 5.2e-11 | -0.07 | 0.08 | 0.64 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PAFAH1B1 | 0.11 | 0.00 | blup | 61 | 0.04 | 3.6e-03 | -1.6 | 6.5 | 6.4e-11 | 0.04 | 0.00 | 0.04 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 1.3e-04 | -5.2 | -6.5 | 7.1e-11 | -0.07 | 0.05 | 0.91 | FALSE |