[Hub]/) : Traits : Impedance of arm (left) :

chr17:6,652,789-8,515,636

Best TWAS P=6.93e-17 · Best GWAS P=3.4e-14 conditioned to 0.189

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SOX15 0.04 0.01 lasso 3 0.01 2.8e-02 -6.32 5.2 2.1e-07 0.39 0.18 0.04 FALSE
2 GTEx Adipose Subcutaneous SNORA48 0.12 0.04 lasso 2 0.04 4.0e-04 -5.45 -5.6 1.8e-08 -0.27 0.38 0.03 FALSE
3 GTEx Cells Transformed fibroblasts TNFSF12 0.25 0.22 lasso 8 0.20 7.4e-15 7.47 7.7 9.9e-15 0.99 0.00 1.00 FALSE
4 GTEx Muscle Skeletal CHRNB1 0.34 0.18 enet 35 0.24 4.9e-23 6.40 -6.0 2.5e-09 -0.63 0.91 0.09 FALSE
5 GTEx Skin Sun Exposed Lower leg ATP1B2 0.08 0.01 lasso 3 0.01 4.8e-02 -5.31 -6.8 1.5e-11 -0.38 0.35 0.10 FALSE
6 GTEx Testis ZBTB4 0.26 0.00 enet 35 0.06 1.6e-03 -5.41 6.0 2.5e-09 0.29 0.05 0.14 FALSE
7 GTEx Whole Blood TNFSF12 0.09 0.03 enet 24 0.04 1.9e-04 7.58 8.3 6.9e-17 0.82 0.00 1.00 TRUE
8 METSIM Adipose ATP1B2 0.07 0.04 bslmm 494 0.03 1.2e-05 -6.47 -6.0 1.8e-09 -0.28 0.81 0.17 FALSE
9 METSIM Adipose CHD3 0.06 0.03 blup 509 0.02 6.7e-04 0.49 5.5 4.9e-08 0.28 0.26 0.08 FALSE
10 METSIM Adipose SENP3 0.06 0.03 lasso 3 0.02 4.9e-04 6.87 -6.5 5.8e-11 -0.79 0.13 0.73 FALSE
11 NTR Blood TNFSF12 0.06 0.07 bslmm 462 0.07 9.4e-23 7.42 6.6 3.6e-11 0.93 0.00 1.00 FALSE
12 ROSMAP Brain Pre-frontal Cortex TNFSF12 0.10 0.04 lasso 6 0.06 9.2e-08 7.47 7.8 5.5e-15 0.90 0.00 1.00 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma ATP1B2 0.06 0.01 blup 39 0.02 4.3e-03 -6.51 -5.6 1.9e-08 -0.34 0.07 0.24 FALSE
14 The Cancer Genome Atlas Colon Adenocarcinoma TNFSF12-TNFSF13 0.07 0.05 lasso 3 0.02 1.9e-02 6.87 7.0 2.1e-12 0.82 0.01 0.91 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CHRNB1 0.04 0.03 blup 57 0.02 1.5e-03 6.40 -5.7 9.7e-09 -0.69 0.00 0.98 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TNFSF12 0.04 0.01 enet 9 0.01 4.3e-02 6.87 -5.9 3.3e-09 -0.74 0.01 0.86 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma ATP1B2 0.04 0.02 blup 39 0.04 2.3e-05 -6.51 -6.5 9.3e-11 -0.34 0.14 0.45 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma TNFSF12-TNFSF13 0.03 0.00 lasso 4 0.01 2.9e-02 7.47 7.0 2.1e-12 0.89 0.00 0.80 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma ATP1B2 0.04 0.01 blup 40 0.01 1.4e-02 -2.08 -5.8 8.9e-09 -0.24 0.01 0.08 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma SHBG 0.04 0.00 blup 59 0.02 4.4e-03 7.32 6.7 1.5e-11 0.65 0.01 0.78 FALSE