[Hub]/) : Traits : Impedance of arm (left) : ← →

chr17:6,652,789-8,515,636

Best TWAS P=6.93e-17 · Best GWAS P=3.4e-14 conditioned to 0.189

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Whole Blood	TNFSF12	0.09	0.03	enet	24	0.04	1.9e-04	7.58	8.3	6.9e-17	0.82	0.00	1.00	TRUE
12	ROSMAP	Brain Pre-frontal Cortex	TNFSF12	0.10	0.04	lasso	6	0.06	9.2e-08	7.47	7.8	5.5e-15	0.90	0.00	1.00	FALSE
3	GTEx	Cells Transformed fibroblasts	TNFSF12	0.25	0.22	lasso	8	0.20	7.4e-15	7.47	7.7	9.9e-15	0.99	0.00	1.00	FALSE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	TNFSF12-TNFSF13	0.07	0.05	lasso	3	0.02	1.9e-02	6.87	7.0	2.1e-12	0.82	0.01	0.91	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	TNFSF12-TNFSF13	0.03	0.00	lasso	4	0.01	2.9e-02	7.47	7.0	2.1e-12	0.89	0.00	0.80	FALSE
5	GTEx	Skin Sun Exposed Lower leg	ATP1B2	0.08	0.01	lasso	3	0.01	4.8e-02	-5.31	-6.8	1.5e-11	-0.38	0.35	0.10	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	SHBG	0.04	0.00	blup	59	0.02	4.4e-03	7.32	6.7	1.5e-11	0.65	0.01	0.78	FALSE
11	NTR	Blood	TNFSF12	0.06	0.07	bslmm	462	0.07	9.4e-23	7.42	6.6	3.6e-11	0.93	0.00	1.00	FALSE
10	METSIM	Adipose	SENP3	0.06	0.03	lasso	3	0.02	4.9e-04	6.87	-6.5	5.8e-11	-0.79	0.13	0.73	FALSE
17	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ATP1B2	0.04	0.02	blup	39	0.04	2.3e-05	-6.51	-6.5	9.3e-11	-0.34	0.14	0.45	FALSE
8	METSIM	Adipose	ATP1B2	0.07	0.04	bslmm	494	0.03	1.2e-05	-6.47	-6.0	1.8e-09	-0.28	0.81	0.17	FALSE
4	GTEx	Muscle Skeletal	CHRNB1	0.34	0.18	enet	35	0.24	4.9e-23	6.40	-6.0	2.5e-09	-0.63	0.91	0.09	FALSE
6	GTEx	Testis	ZBTB4	0.26	0.00	enet	35	0.06	1.6e-03	-5.41	6.0	2.5e-09	0.29	0.05	0.14	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TNFSF12	0.04	0.01	enet	9	0.01	4.3e-02	6.87	-5.9	3.3e-09	-0.74	0.01	0.86	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ATP1B2	0.04	0.01	blup	40	0.01	1.4e-02	-2.08	-5.8	8.9e-09	-0.24	0.01	0.08	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHRNB1	0.04	0.03	blup	57	0.02	1.5e-03	6.40	-5.7	9.7e-09	-0.69	0.00	0.98	FALSE
2	GTEx	Adipose Subcutaneous	SNORA48	0.12	0.04	lasso	2	0.04	4.0e-04	-5.45	-5.6	1.8e-08	-0.27	0.38	0.03	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ATP1B2	0.06	0.01	blup	39	0.02	4.3e-03	-6.51	-5.6	1.9e-08	-0.34	0.07	0.24	FALSE
9	METSIM	Adipose	CHD3	0.06	0.03	blup	509	0.02	6.7e-04	0.49	5.5	4.9e-08	0.28	0.26	0.08	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SOX15	0.04	0.01	lasso	3	0.01	2.8e-02	-6.32	5.2	2.1e-07	0.39	0.18	0.04	FALSE