Best TWAS P=3.89e-11 · Best GWAS P=8.76e-11 conditioned to 0.0496
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | C17orf103 | 0.16 | 0.06 | lasso | 5 | 0.06 | 2.1e-04 | 4.9 | -5.3 | 1.1e-07 | -0.34 | 0.18 | 0.44 | FALSE |
| 2 | GTEx | Lung | C17orf103 | 0.08 | 0.01 | enet | 11 | 0.04 | 6.6e-04 | -4.0 | -5.3 | 1.3e-07 | -0.53 | 0.18 | 0.43 | FALSE |
| 3 | GTEx | Testis | C17orf103 | 0.15 | 0.21 | enet | 4 | 0.19 | 7.1e-09 | 5.5 | -6.0 | 1.5e-09 | -0.33 | 0.34 | 0.65 | FALSE |
| 4 | GTEx | Thyroid | KCNJ12 | 0.36 | 0.23 | lasso | 5 | 0.25 | 2.9e-19 | 5.0 | 6.6 | 3.9e-11 | 0.81 | 0.60 | 0.40 | TRUE |
| 5 | NTR | Blood | C17orf103 | 0.02 | 0.02 | lasso | 2 | 0.02 | 1.6e-07 | 5.0 | -5.5 | 3.7e-08 | -0.33 | 0.80 | 0.19 | FALSE |