TWAS hub - C17orf103

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Muscularis	0.1580	0.0660	4.1e-03	0.060	NA	0.031	NA	0.058	1.7e-04	NA	5.5e-03	NA	2.1e-04
2	GTEx	Lung	0.0766	0.0331	4.3e-03	0.011	NA	0.038	NA	0.030	4.5e-02	NA	6.6e-04	NA	2.4e-03
3	GTEx	Skin Sun Exposed Lower leg	0.1140	0.0350	4.9e-05	0.022	NA	0.074	NA	0.052	5.5e-03	NA	1.0e-06	NA	4.0e-05
4	GTEx	Testis	0.1510	0.0570	2.9e-03	0.214	NA	0.191	NA	0.187	6.9e-10	NA	7.1e-09	NA	9.9e-09
5	METSIM	Adipose	0.0767	0.0247	1.9e-05	0.012	0.042	0.039	0.043	0.032	4.9e-03	5.3e-07	1.4e-06	4.0e-07	1.2e-05
6	NTR	Blood	0.0230	0.0097	2.0e-03	0.023	0.008	0.012	0.013	0.021	3.6e-08	9.5e-04	8.3e-05	2.7e-05	1.6e-07
7	ROSMAP	Brain Pre-frontal Cortex	0.1609	0.0406	9.5e-10	0.053	0.096	0.125	0.109	0.100	2.1e-07	2.6e-12	8.7e-16	6.4e-14	8.4e-13
8	TCGA	Breast Invasive Carcinoma	0.0345	0.0159	6.4e-05	0.040	0.015	0.027	NA	0.035	1.0e-08	3.0e-04	2.7e-06	NA	7.9e-08
9	TCGA	Brain Lower Grade Glioma	0.0513	0.0272	3.9e-03	0.035	0.009	0.010	NA	0.016	6.1e-05	2.6e-02	2.2e-02	NA	5.4e-03
10	TCGA	Pheochromocytoma and Paraganglioma	0.1300	0.0580	1.2e-03	0.138	0.075	0.077	NA	0.114	3.8e-06	6.6e-04	5.7e-04	NA	2.9e-05
11	TCGA	Thyroid Carcinoma	0.0780	0.0370	6.7e-04	0.008	0.010	0.009	NA	0.009	5.4e-02	3.2e-02	4.2e-02	NA	4.2e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Exposure to tobacco smoke outside home	9.5	12.7	24.8	3.7	4.7	5.0	3.7	-0.0	3.9	2.4	3.8	3.0	3.8	2.6
Hearing aid user	8.5	9.6	12.6	3.2	2.8	2.0	2.8	3.4	3.4	2.6	3.5	3.6	3.5	3.1
Age at first live birth	5.7	10.1	17.9	-3.3	-3.8	-2.3	-4.2	-1.2	-3.9	-1.6	-3.6	-3.3	-3.6	-2.6
Qualifications: O levels/GCSEs or equivalent	5.5	8.7	14.1	-2.5	-3.8	-3.5	-3.7	-1.6	-3.3	-3.5	-2.8	-2.6	-2.8	-1.2
Impedance of arm (right)	5.1	24.0	37.2	-5.5	-5.3	-3.6	-6.1	-0.7	-5.8	-2.9	-5.4	-5.4	-5.4	-5.0
Body mass index (BMI)	5.0	21.4	36.4	5.0	6.0	5.5	5.4	-0.9	4.9	3.5	4.4	4.0	4.4	4.7
BMI	4.8	28.1	53.4	5.7	7.3	6.5	5.9	0.3	5.5	4.0	5.1	4.6	5.1	5.3
Impedance of arm (left)	4.8	22.1	36.5	-5.3	-5.3	-3.7	-6.0	-0.6	-5.5	-2.8	-5.0	-5.0	-5.0	-4.9
Standing height	4.7	46.7	91.2	-7.2	-9.6	-8.7	-7.6	0.7	-7.0	-4.6	-6.5	-6.0	-6.5	-6.8
Leg fat percentage (left)	4.6	16.6	34.0	4.4	5.6	5.8	4.6	-2.7	3.9	2.9	3.5	2.7	3.5	3.7
Townsend deprivation index at recruitment	4.5	6.3	9.3	3.0	2.3	2.7	3.0	-0.1	3.1	1.8	2.9	2.5	2.9	1.9
Number of live births	4.4	6.2	11.6	3.4	1.3	0.7	3.2	-0.0	3.1	1.5	3.0	3.0	3.0	2.2
Leg fat percentage (right)	4.4	15.8	32.6	4.2	5.7	5.7	4.5	-2.3	3.8	2.9	3.4	2.7	3.4	3.7
Body Mass Index (BMI) (2010)	4.3	5.9	14.2	2.0	3.8	2.6	2.6	0.7	2.6	1.3	2.5	2.4	2.5	2.3
Taking other prescription medications	4.3	6.6	11.6	3.0	3.1	2.0	3.4	0.1	3.0	1.5	2.7	2.6	2.7	2.3
Mood swings	4.1	7.5	17.1	4.1	2.3	1.7	2.7	2.9	2.4	2.4	2.3	2.1	2.3	3.8
Height	3.9	75.4	146.4	-9.0	-12.1	-10.6	-9.6	0.8	-9.1	-5.6	-8.4	-8.1	-8.4	-8.6
Medication: Lansoprazole	3.6	4.1	10.2	2.0	2.5	2.1	3.2	-0.6	2.5	1.4	2.1	1.7	2.1	0.8
Overall health rating	3.4	7.3	21.4	2.7	3.4	4.6	3.3	-0.9	2.5	2.8	2.1	1.4	2.1	2.1
Average weekly fortified wine intake	3.3	3.9	7.1	-2.7	-1.5	-1.4	-2.6	-0.3	-2.6	-1.0	-2.4	-2.1	-2.4	-1.0
Cholesterol lowering medication	3.3	4.8	9.7	1.8	3.1	2.3	3.1	0.8	2.4	2.2	1.8	1.8	1.8	2.1
Diverticular disease/diverticulitis (self-reported)	3.2	3.8	7.2	2.7	1.6	-0.1	2.1	1.6	2.3	0.5	2.3	2.5	2.3	1.6
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.3	11.0	2.7	2.3	1.6	3.1	1.7	3.1	2.2	2.9	3.3	2.9	3.3
Medication: Simvastatin	3.1	4.5	10.6	2.6	3.0	2.1	2.7	0.8	1.8	1.6	1.4	1.3	1.4	3.2
Medication: Omeprazole (e.g. Zanprol)	3.1	3.8	6.6	2.2	0.8	1.7	2.0	-0.5	2.5	2.0	2.6	2.4	2.6	0.8
Pain type(s) experienced in last month: Hip pain	3.0	3.8	7.8	1.9	2.8	2.8	2.1	0.0	2.0	1.7	1.8	1.5	1.8	1.5
Lupus	2.9	4.4	8.2	-1.8	-2.4	-1.5	-2.9	-0.1	-2.5	-2.3	-2.1	-2.4	-2.1	-1.6
Supplements: Vitamin C	2.9	3.4	8.2	-2.9	-1.3	-0.9	-1.3	-1.7	-1.7	-1.2	-1.9	-2.1	-1.9	-2.5
Breast cancer (self-reported)	2.9	3.4	8.1	2.0	2.9	2.0	2.4	1.4	1.8	0.7	1.6	1.4	1.6	2.0
Wears glasses or contact lenses	2.9	3.3	6.2	-1.7	-2.5	-1.6	-2.1	-1.3	-2.0	-1.4	-1.9	-1.9	-1.9	-1.5
Leg fat mass (left)	2.9	11.2	18.6	3.8	4.3	4.3	3.9	-1.5	3.4	2.6	3.0	2.5	3.0	3.4
Age at last live birth	2.8	4.0	6.0	-2.5	-1.6	-1.4	-2.4	-1.7	-2.4	-1.2	-2.4	-2.1	-2.4	-1.6
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.3	5.9	0.7	2.4	2.1	2.4	-0.6	2.4	1.7	2.0	1.8	2.0	0.0
Ever had hysterectomy (womb removed)	2.7	3.0	8.7	0.3	3.0	2.8	1.9	0.1	1.7	2.1	1.4	1.3	1.4	-0.5
Age when periods started (menarche)	2.7	6.5	9.1	-2.8	-2.6	-3.0	-2.8	0.9	-2.7	-2.2	-2.5	-2.5	-2.5	-2.8
Leg fat mass (right)	2.7	10.3	18.6	3.6	4.3	4.1	3.7	-1.3	3.2	2.5	2.9	2.4	2.9	3.3
Impedance of whole body	2.7	13.6	24.7	-4.1	-3.9	-2.5	-5.0	-0.8	-4.4	-2.2	-3.9	-4.0	-3.9	-4.0
Tinnitus: Yes, but not now, but have in the past	2.6	2.7	9.3	1.7	2.8	3.1	1.7	-0.5	1.3	0.9	1.1	0.7	1.1	1.1
Sitting height	2.6	18.4	34.2	-4.5	-5.5	-5.8	-4.8	0.5	-4.6	-3.3	-4.3	-3.8	-4.3	-3.5
Mouth/teeth dental problems: Bleeding gums	2.6	3.3	6.3	-2.1	-1.7	-0.8	-2.5	-1.8	-2.2	-0.9	-2.0	-2.1	-2.0	-1.3
Medication: Omeprazole	2.6	3.2	5.1	2.0	0.7	1.6	2.1	-0.4	2.3	1.9	2.2	2.0	2.2	0.7
HDL Cholesterol	2.5	4.2	7.8	-2.1	-2.2	-2.8	-2.4	0.1	-1.9	-2.6	-1.6	-1.7	-1.6	-2.0
Hair/balding pattern: Pattern 4	2.5	6.0	9.6	-3.0	-1.4	-1.4	-2.0	-1.9	-2.7	-2.3	-3.0	-3.1	-3.0	-2.4
Body fat percentage	2.5	10.0	22.6	3.3	4.5	4.8	3.4	-1.8	3.0	2.5	2.7	2.0	2.7	2.8
Other serious medical condition/disability diagnosed by doctor	2.4	3.1	8.2	2.0	1.0	0.2	2.1	2.9	1.9	1.1	1.7	1.8	1.7	1.2
Eye problems/disorders: Diabetes related eye disease	2.4	2.6	4.5	2.1	0.6	0.2	1.4	2.0	1.7	0.7	1.8	1.9	1.8	1.9
Exposure to tobacco smoke at home	2.4	2.7	5.3	1.4	2.3	2.3	1.8	-0.8	1.7	2.0	1.5	1.3	1.5	1.0
Commuting to job workplace: Cycle	2.4	2.9	5.8	1.8	0.8	0.6	1.3	2.4	1.9	1.2	2.2	2.3	2.2	0.5
HbA1C	2.3	2.6	4.0	1.6	1.6	1.6	1.5	-0.1	1.9	2.0	1.9	1.9	1.9	0.6
Prostate Cancer	2.2	3.1	4.8	1.3	2.0	1.8	2.2	-0.9	2.2	1.7	2.0	2.0	2.0	0.8
Diabetes (father)	2.2	2.7	6.4	0.7	1.9	0.2	2.5	-0.3	2.4	1.3	2.0	2.0	2.0	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	2.2	4.9	7.9	1.7	2.3	1.0	2.6	1.9	2.6	1.2	2.4	2.8	2.4	2.6
Commuting to job workplace: Car/motor vehicle	2.2	2.5	5.3	-1.7	-0.2	-0.6	-0.9	-1.3	-1.6	-2.3	-1.8	-1.8	-1.8	-1.9
Medication: Aspirin	2.2	2.9	6.6	2.1	2.5	0.7	2.6	1.7	1.7	-0.3	1.2	1.2	1.2	2.0
Medication: Aspirin	2.2	2.8	6.5	2.2	2.1	0.4	2.5	1.7	1.7	-0.5	1.2	1.3	1.2	2.1
Ever depressed for a whole week	2.2	2.7	4.7	-1.6	-0.8	-1.5	-1.9	0.6	-2.2	-1.6	-2.1	-2.1	-2.1	-0.3
Hand grip strength (left)	2.1	5.5	11.9	-3.5	-1.5	-1.8	-2.9	-2.1	-2.8	-1.6	-2.7	-2.3	-2.7	-0.7
Medication: Metformin	2.1	2.9	4.8	1.7	2.1	0.6	2.2	1.6	2.0	0.2	1.7	1.6	1.7	2.1
Relative age voice broke	2.1	3.2	6.1	0.9	1.6	1.1	2.0	0.8	2.3	2.0	2.3	2.5	2.3	0.6
Medication for pain relief, constipation, heartburn	2.1	3.6	6.3	-2.5	-2.0	-1.5	-2.1	-1.2	-2.2	-1.0	-2.2	-2.0	-2.2	-1.6
Arm fat percentage (left)	2.1	8.5	17.6	3.0	4.2	4.2	3.0	-1.3	2.8	2.3	2.5	2.0	2.5	2.9
Serious illness, injury or assault to yourself	2.0	2.4	6.2	1.8	1.9	1.7	2.5	0.6	1.5	0.9	1.0	0.9	1.0	1.8
Number of full brothers	2.0	2.6	4.2	1.1	2.0	1.6	1.6	-0.6	2.0	1.1	2.0	1.8	2.0	0.8
Bipolar Disorder or Schizophrenia	1.9	4.6	8.8	2.9	-0.2	0.6	1.8	1.2	2.5	2.1	2.7	3.0	2.7	1.7
Pack years adult smoking proportion	1.9	2.9	6.4	2.5	0.8	1.0	2.2	0.2	2.2	0.9	2.1	1.8	2.1	1.1
Waist circumference	1.9	7.1	13.9	2.7	3.7	3.5	3.5	-1.3	2.7	2.1	2.2	1.7	2.2	2.5
Pain all over the body in last month	1.9	2.1	4.4	-1.1	-2.0	-2.1	-1.2	-1.1	-1.1	-2.0	-1.0	-1.2	-1.0	-1.4
Neck or shoulder pain in last month	1.9	2.7	5.9	2.4	1.4	2.2	1.1	1.0	1.5	1.6	1.6	1.2	1.6	2.0
Unable to work because of sickness or disability	1.9	2.5	5.4	2.3	1.4	1.2	2.3	0.5	2.0	0.6	1.7	1.4	1.7	1.1
Schizophrenia (2018)	1.8	3.7	6.5	2.4	0.1	0.3	1.7	1.7	2.2	1.7	2.3	2.6	2.3	1.9
Hypothyroidism (self reported)	1.8	4.1	9.3	2.1	2.5	2.4	3.0	0.7	2.3	1.6	1.9	1.6	1.9	1.2
Type 2 Diabetes (T2D) (2018)	1.8	3.4	10.7	2.4	2.2	0.4	1.7	2.0	1.6	0.1	1.5	1.5	1.5	3.3
Arm fat percentage (right)	1.8	7.2	16.3	2.7	4.0	4.0	2.9	-1.5	2.4	2.2	2.1	1.7	2.1	2.7
Migraine (self-reported)	1.8	2.3	3.8	-0.7	-1.9	-1.9	-1.7	0.5	-1.9	-1.1	-1.8	-1.3	-1.8	1.3
Alcohol intake frequency.	1.8	4.1	6.8	2.6	0.3	1.0	2.3	0.4	2.6	2.4	2.6	2.3	2.6	1.1
Comparative height size at age 10	1.8	9.8	21.6	-2.9	-4.6	-4.7	-3.7	0.2	-3.2	-2.3	-2.8	-2.5	-2.8	-2.3
Average weekly champagne plus white wine intake	1.8	2.5	4.0	-1.4	-1.3	-0.8	-1.9	-1.8	-2.0	-0.3	-1.9	-1.8	-1.9	-1.2
Fractured/broken bones in last 5 years	1.8	2.3	6.0	1.2	1.9	2.3	1.3	0.2	1.3	2.4	1.3	1.3	1.3	0.9
Relative age of first facial hair	1.7	3.6	5.1	1.3	1.9	1.9	2.1	0.7	2.2	2.1	2.1	2.2	2.1	1.5
Diabetes (self-reported)	1.7	2.7	5.5	2.3	1.9	0.3	2.0	1.9	1.6	-0.3	1.4	1.1	1.4	2.2
Family relationship satisfaction	1.7	2.0	4.1	1.4	2.0	1.7	1.2	1.6	1.3	1.4	1.3	1.1	1.3	1.1
Arm fat mass (left)	1.7	6.9	12.0	2.8	3.5	3.2	2.9	-0.7	2.8	2.2	2.6	2.2	2.6	2.6
Primary Biliary Cirrhosis	1.6	2.3	4.8	1.2	1.8	2.2	1.2	1.0	1.3	1.8	1.3	1.1	1.3	1.8
Supplements: Glucosamine	1.6	2.1	3.1	-1.2	-0.9	-1.6	-1.0	-1.0	-1.4	-1.8	-1.6	-1.6	-1.6	-1.8
High blood pressure (mother)	1.6	2.3	3.7	1.0	0.9	0.2	1.5	1.8	1.8	1.2	1.7	1.9	1.7	1.8
Falls in the last year	1.6	2.2	4.5	1.2	2.1	2.1	1.3	0.9	1.4	1.5	1.4	1.3	1.4	1.3
Medication: Paracetamol	1.6	2.6	5.0	2.2	1.3	1.1	1.3	1.4	1.7	1.4	1.9	1.8	1.9	1.4
Eye problems/disorders: None of the above	1.6	1.8	3.8	-1.1	-1.2	-0.2	-1.8	-0.4	-1.9	0.2	-1.8	-1.8	-1.8	0.2
Medication: Allopurinol	1.6	2.1	5.2	2.3	-0.3	0.1	1.1	1.7	1.3	1.0	1.5	1.8	1.5	1.8
Long-standing illness, disability or infirmity	1.6	2.4	5.2	1.7	2.0	1.8	2.3	-0.1	1.5	1.6	1.0	1.1	1.0	1.9
Ever had bowel cancer screening	1.6	1.8	5.2	-0.6	-0.8	0.1	-1.0	-2.3	-1.6	-0.8	-1.7	-1.9	-1.7	-0.2
Lung FVC	1.5	7.9	12.5	2.4	2.7	3.5	3.3	-1.0	3.3	2.6	3.1	3.2	3.1	1.8
Number of treatments/medications taken	1.5	2.7	7.1	2.7	2.0	0.4	2.2	1.3	1.6	0.5	1.3	1.2	1.3	2.2
Diabetes (mother)	1.5	1.9	3.3	1.4	1.8	1.7	0.7	1.5	1.2	0.6	1.5	1.3	1.5	1.3
Qualifications: A levels/AS levels or equivalent	1.5	3.4	8.8	-2.0	-3.0	-2.2	-2.5	0.4	-1.8	-1.5	-1.5	-1.2	-1.5	-1.5
Arm fat mass (right)	1.5	6.2	11.4	2.6	3.4	3.2	2.8	-1.2	2.5	2.1	2.3	1.9	2.3	2.4
Hypothyroidism/myxoedema (self-reported)	1.5	2.9	6.3	2.0	1.5	1.5	2.5	1.0	1.9	1.2	1.6	1.6	1.6	1.6
Whole body fat mass	1.5	6.3	10.7	2.8	3.3	3.3	2.9	-1.1	2.5	2.1	2.3	1.8	2.3	2.5
Ever taken oral contraceptive pill	1.5	1.6	3.0	-1.5	-1.7	-0.6	-1.4	-1.7	-1.2	-1.0	-1.0	-0.8	-1.0	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	3.1	1.7	1.0	1.4	1.7	-0.6	1.3	1.6	1.1	1.1	1.1	1.8
Suffer from ‘nerves’	1.4	2.2	4.4	-1.1	-0.8	-0.4	-1.3	-2.1	-1.6	-0.8	-1.7	-2.1	-1.7	-1.8
Eye problems/disorders: Cataract	1.4	1.7	3.3	1.4	1.8	1.2	1.6	0.1	1.6	0.4	1.5	1.3	1.5	0.2
Guilty feelings	1.4	2.2	3.7	-1.9	-0.2	-1.0	-1.1	-1.4	-1.5	-1.0	-1.7	-1.9	-1.7	-1.9
Pack years of smoking	1.4	2.0	4.7	2.2	0.7	1.1	1.8	0.1	1.8	0.9	1.7	1.4	1.7	0.7
Crohns Disease (2017)	1.3	2.8	6.1	1.3	1.8	1.5	2.5	0.3	2.3	0.7	2.0	1.7	2.0	0.3
Blood Platelet Count	1.3	15.5	22.4	3.7	4.6	3.1	4.3	1.7	4.7	2.5	4.6	4.7	4.6	3.3
Trunk fat percentage	1.3	5.3	13.5	2.4	3.3	3.7	2.4	-1.4	2.1	1.8	2.0	1.4	2.0	1.9
Diabetes diagnosed by doctor	1.3	2.2	5.9	2.3	1.4	0.2	1.8	1.4	1.4	-0.2	1.2	1.0	1.2	2.4
Age at First Birth	1.2	1.7	2.8	-1.6	-1.1	-1.6	-1.4	0.1	-1.4	-1.0	-1.4	-1.1	-1.4	-1.7
Fasting Glucose	1.2	1.4	3.7	-0.9	-1.2	-0.9	-1.1	-1.4	-1.2	-1.9	-1.2	-0.9	-1.2	0.6
Schizophrenia (2014)	1.2	2.6	5.4	2.0	-0.1	0.3	1.7	1.1	2.0	1.5	2.1	2.3	2.1	0.7
Medication for hormone replacement therapy	1.2	1.4	2.5	-1.5	-1.2	-1.4	-1.0	-0.9	-1.0	-1.0	-1.0	-0.9	-1.0	-1.6
Qualifications: College or University degree	1.2	3.7	6.8	-2.4	-2.3	-1.1	-2.6	-0.4	-2.2	-0.8	-1.9	-1.6	-1.9	-2.5
Number of full sisters	1.2	1.4	4.4	1.9	1.4	1.8	0.5	0.5	0.5	0.5	0.6	0.5	0.6	2.1
Number of self-reported non-cancer illnesses	1.2	2.1	6.2	2.5	1.1	1.3	1.7	0.1	1.3	1.2	1.2	1.4	1.2	1.9
Neuroticism (2016)	1.1	1.6	4.3	1.2	1.7	2.1	1.9	0.3	1.1	1.5	0.7	0.6	0.7	1.1
Blood clot in the leg (DVT)	1.1	1.4	4.9	1.1	1.3	0.8	2.2	-0.4	1.6	0.2	1.2	1.1	1.2	0.0
Worry too long after embarrassment	1.1	1.8	3.4	-1.1	-1.2	-0.3	-1.8	-1.1	-1.8	-0.9	-1.6	-1.8	-1.6	-0.8
Smoking status: Current	1.1	1.8	3.4	1.4	0.7	0.1	1.4	-0.2	1.7	0.7	1.7	1.8	1.7	1.4
Medication: Paracetamol	1.1	1.8	5.3	2.3	0.6	0.6	1.3	0.5	1.4	1.2	1.5	1.3	1.5	1.4
Ever smoked	1.1	1.9	10.3	-0.2	-3.2	-2.4	-0.8	1.0	-0.6	-1.2	-0.4	-0.3	-0.4	-1.1
Alzheimer’s Disease (in father)	1.0	1.1	3.0	-0.6	-1.1	-1.3	-1.7	0.4	-1.3	-0.7	-1.0	-0.9	-1.0	-0.2
Mean Putamen Volume	1.0	1.2	3.5	1.8	0.8	0.7	0.4	0.5	0.8	0.8	1.0	1.2	1.0	1.9
Triglycerides	1.0	1.6	2.7	1.6	1.0	1.1	1.6	-0.5	1.6	0.6	1.4	1.4	1.4	1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.2	9.9	-1.3	0.6	0.7	-0.3	-3.1	-0.1	0.2	-0.2	-0.1	-0.2	-0.7
Severe depression (siblings)	1.0	1.1	2.7	-1.2	-1.1	-0.3	-1.6	-1.3	-1.2	0.1	-1.0	-0.8	-1.0	-0.7
Impedance of leg (right)	1.0	4.8	9.2	-2.5	-1.7	-0.8	-3.0	-1.2	-2.7	-1.1	-2.4	-2.5	-2.4	-2.4
Impedance of leg (left)	1.0	4.8	8.7	-2.2	-1.9	-0.7	-3.0	-1.8	-2.6	-1.2	-2.3	-2.5	-2.3	-2.5
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.1	-1.3	-1.3	-1.8	-1.0	0.5	-1.0	-0.6	-1.0	-0.9	-1.0	-1.2
Qualifications: None of the above	1.0	2.2	5.4	2.3	1.1	0.6	2.0	0.6	1.6	1.0	1.4	1.3	1.4	1.9
Breastfed as a baby	1.0	1.2	2.4	0.1	-1.6	-1.3	-1.1	1.5	-1.2	-1.1	-1.0	-1.0	-1.0	0.4
Heart disease (mother)	1.0	1.2	1.9	1.2	0.5	0.7	1.1	-0.1	1.3	0.9	1.4	1.3	1.4	1.1
Chest pain or discomfort	1.0	1.5	2.5	1.3	0.9	1.4	1.4	-0.2	1.5	1.6	1.5	1.0	1.5	0.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	4.4	1.3	1.1	0.7	2.1	-0.1	1.5	0.1	1.1	1.0	1.1	0.1
Financial difficulties in last 2 years	0.9	1.3	2.5	-1.5	-0.2	-1.2	-0.7	-0.6	-1.3	-0.9	-1.6	-1.3	-1.6	-0.2
Fluid intelligence score	0.9	1.8	3.5	-1.9	-1.6	-1.8	-0.5	-0.9	-0.9	-1.8	-1.2	-0.9	-1.2	-1.6
Medication: Cholesterol lowering	0.9	1.3	4.3	0.8	-0.3	-0.4	-0.5	-0.9	-1.2	-1.3	-1.3	-1.5	-1.3	2.1
Prospective memory result	0.9	1.1	3.2	-1.1	-0.7	0.7	-1.8	-1.0	-1.3	0.2	-0.9	-1.4	-0.9	-0.6
Pulse wave Arterial Stiffness index	0.9	1.0	3.6	-0.5	-1.8	-1.0	-1.9	-0.0	-1.0	-0.3	-0.5	-0.4	-0.5	-1.1
Gout (self-reported)	0.9	1.2	2.5	1.6	0.2	0.2	0.9	0.7	1.1	0.9	1.2	1.5	1.2	1.4
Wheeze or whistling in the chest in last year	0.9	1.7	5.1	1.1	2.2	1.6	1.6	0.1	1.3	0.8	1.0	1.1	1.0	1.2
Eye problems/disorders: Glaucoma	0.9	1.0	3.9	-1.3	-0.4	-1.4	0.1	-1.0	-0.2	-1.3	-0.4	-0.4	-0.4	-2.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.7	-0.9	-0.6	-0.8	-1.4	-0.7	-1.0	-1.6	-0.8	-1.1	-0.8	-1.6
Bipolar Disorder (2018)	0.8	1.2	2.5	1.6	-0.6	0.5	0.8	-0.1	1.3	1.2	1.5	1.6	1.5	0.4
LDL Cholesterol	0.8	1.2	6.3	0.9	2.5	1.7	0.7	0.4	0.7	0.3	0.7	0.5	0.7	0.7
Ulcerative Colitis	0.8	1.1	7.3	-0.8	-0.1	-0.4	0.5	-1.8	0.1	-0.5	-0.2	-0.3	-0.2	-2.7
Angina	0.8	1.0	2.5	1.2	0.6	0.8	1.6	-1.4	1.2	0.3	0.9	0.7	0.9	0.6
Medication: Co-codamol	0.8	1.0	1.9	0.6	0.7	1.4	0.9	-0.1	1.1	1.4	1.1	1.2	1.1	0.5
Illnesses of siblings	0.8	1.2	3.2	-1.0	-1.6	-0.7	-0.3	-1.5	-0.7	-0.2	-0.8	-1.1	-0.8	-1.8
High blood pressure (siblings)	0.8	1.2	3.1	0.4	1.7	0.8	0.3	1.8	0.5	1.4	0.7	1.1	0.7	1.4
Health satisfaction	0.8	1.0	3.3	0.8	1.1	1.2	0.7	1.5	0.1	1.8	-0.2	-0.1	-0.2	1.4
Pulse rate, automated reading	0.8	2.4	7.2	1.6	2.7	1.7	2.0	1.0	1.5	1.1	1.1	1.1	1.1	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	5.4	-1.1	-2.3	-1.9	-1.3	1.2	-0.9	-0.5	-0.7	-0.6	-0.7	-1.7
Qualifications: nursing, teaching	0.8	1.3	3.2	-1.8	-1.7	-0.8	-1.4	0.3	-1.1	-0.4	-1.0	-0.6	-1.0	-1.3
Miserableness	0.8	1.4	4.0	1.7	-0.1	0.1	1.1	2.0	0.9	1.0	0.8	0.9	0.8	1.7
Myopia	0.8	1.1	3.1	-1.4	-1.1	-1.8	-0.9	0.2	-1.1	-0.9	-1.1	-0.8	-1.1	-0.4
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.0	-1.3	-2.0	-2.2	-0.5	-0.5	-0.8	-1.5	-0.9	-0.7	-0.9	-1.3
Crohns Disease (2012)	0.7	1.1	2.6	0.0	0.0	0.5	1.6	0.5	1.6	0.3	1.5	1.3	1.5	-0.2
Current tobacco smoking	0.7	1.2	2.1	1.4	0.3	-0.1	1.2	-0.4	1.3	0.5	1.3	1.4	1.3	1.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.6	-0.0	1.6	0.6	0.6	-0.5	1.0	0.1	1.0	0.9	1.0	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.9	3.5	0.4	1.9	0.7	0.3	-1.1	-0.5	-1.1	-0.7	-1.0	-0.7	0.5
Trunk fat mass	0.7	3.1	7.3	1.9	2.5	2.7	1.9	-1.2	1.6	1.4	1.5	1.0	1.5	1.5
Nervous feelings	0.7	1.3	2.8	-0.8	-0.4	0.5	-1.3	-1.7	-1.5	0.5	-1.4	-1.7	-1.4	-0.2
Had menopause	0.7	0.8	2.2	-0.6	-1.1	-0.8	-0.6	0.1	-0.9	0.7	-1.0	-1.2	-1.0	-1.5
Pulse rate	0.7	1.2	2.8	1.2	1.2	1.7	1.0	0.1	1.1	1.4	1.1	0.9	1.1	0.4
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	4.2	-1.1	-0.9	-0.6	-0.2	1.0	0.6	1.5	0.8	0.9	0.8	-2.0
Shortness of breath walking on level ground	0.7	0.8	2.3	0.2	1.5	1.1	1.1	1.2	0.8	1.1	0.6	0.4	0.6	0.0
Medication: Seretide 50 evohaler	0.7	0.8	1.3	-0.8	-0.4	-0.5	-1.1	0.3	-1.1	-0.2	-1.1	-1.1	-1.1	-1.1
Commuting to job workplace: Public transport	0.7	0.8	1.3	-1.1	-0.9	-0.8	-1.0	-0.4	-1.1	-0.1	-1.0	-1.0	-1.0	-0.8
Number of operations (self-reported)	0.7	1.1	2.9	0.7	1.2	0.8	1.1	1.7	1.0	1.1	0.9	0.9	0.9	0.9
Risk taking	0.7	1.1	2.5	1.5	0.4	0.0	0.3	1.6	1.0	-0.3	1.3	1.2	1.3	1.0
Basal cell carcinoma (self-reported)	0.7	0.9	2.8	0.8	-1.1	-1.4	0.8	1.7	0.6	0.4	0.5	0.8	0.5	0.0
Irritable Bowel Disease (IBD)	0.6	1.5	4.2	0.3	1.4	1.3	2.0	-0.6	1.6	0.5	1.2	1.0	1.2	-1.2
Major Depression (MDD)	0.6	0.7	1.5	0.5	0.0	1.0	1.0	0.0	1.2	0.6	1.2	1.1	1.2	0.4
Ovarian Cancer	0.6	0.8	2.9	0.9	0.3	1.7	0.8	-0.6	0.6	1.6	0.5	0.4	0.5	0.2
Blood Eosinophil Count	0.6	4.3	11.4	2.9	0.5	0.8	0.8	2.3	1.7	1.4	2.3	2.3	2.3	3.4
Waist Hip Ratio (WHR)	0.6	2.9	5.1	2.2	2.0	1.6	2.3	0.5	1.8	1.0	1.5	1.5	1.5	1.9
Allergy or Eczema	0.6	1.5	6.6	0.9	-1.9	-2.0	-0.7	2.6	-0.6	0.2	-0.3	-0.2	-0.3	0.5
Vitamin and mineral supplements	0.6	0.8	1.5	1.1	-0.2	0.0	1.0	-0.4	1.1	0.5	1.1	1.2	1.1	0.8
Hand grip strength (right)	0.6	1.8	3.1	-1.7	-0.8	-1.0	-1.8	-1.6	-1.5	-1.0	-1.4	-1.3	-1.4	-0.5
Stomach or abdominal pain in last month	0.6	0.8	1.8	1.3	0.8	1.1	1.2	-0.3	0.7	0.9	0.5	0.6	0.5	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.6	1.3	0.0	0.2	1.3	1.9	0.7	1.0	0.5	0.4	0.5	1.1
Father’s age at death	0.6	0.7	5.4	-1.3	0.2	-0.5	-0.2	0.5	-0.2	-0.4	-0.4	-0.5	-0.4	-2.3
Happiness	0.6	0.7	3.5	0.1	0.4	0.7	-0.7	1.9	-0.6	1.3	-0.5	-0.4	-0.5	0.8
Medication: Amlodipine	0.6	0.8	2.3	0.7	0.8	0.9	0.3	1.5	0.5	0.8	0.6	0.7	0.6	1.5
Had major operations	0.6	0.7	2.1	0.5	1.4	0.8	1.1	1.2	0.8	0.8	0.5	0.5	0.5	0.3
Smoking status: Previous	0.6	1.0	4.2	-0.6	-2.0	-0.8	-0.4	-0.4	-0.7	-0.4	-0.8	-0.9	-0.8	-1.5
Loneliness, isolation	0.6	0.9	5.2	0.6	0.9	-0.1	0.7	2.3	0.5	0.1	0.5	0.4	0.5	1.3
Friendships satisfaction	0.6	0.8	2.0	0.8	1.4	1.4	0.2	0.8	0.7	1.0	0.8	0.6	0.8	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.8	2.0	0.2	1.1	0.8	1.4	-0.5	1.1	1.0	0.8	0.8	0.8	0.3
Medication: Gliclazide	0.6	0.7	3.9	0.9	0.1	-0.9	-0.4	0.8	-0.5	-0.9	-0.4	-0.3	-0.4	2.0
Illnesses of father: None of the above (group 1)	0.6	0.8	3.4	0.5	-1.8	-1.2	0.4	0.7	0.5	0.6	0.5	0.7	0.5	-1.0
Financial situation satisfaction	0.6	0.7	3.2	0.4	0.3	0.7	0.0	1.8	-0.3	1.3	-0.4	-0.3	-0.4	1.2
Alcohol drinker status: Previous	0.6	0.6	3.4	0.1	-1.8	-1.6	-0.3	-0.6	0.0	0.5	0.2	0.4	0.2	-0.4
Depressed Affect (Nagel 2018)	0.5	1.1	4.8	1.5	-0.1	0.0	0.7	2.2	0.3	1.5	0.2	0.3	0.2	1.6
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.5	-1.1	-2.1	-1.8	-0.7	-0.8	-0.8	-1.1	-0.9	-0.7	-0.9	-1.9
Rheumatoid Arthritis	0.5	0.6	3.1	-0.6	0.8	1.8	0.4	-0.7	0.2	1.4	0.0	-0.3	0.0	-0.5
Heel T-Score	0.5	4.2	7.6	1.3	2.3	1.6	2.2	0.7	2.4	1.8	2.3	2.8	2.3	1.9
Smoking Status	0.5	1.1	2.5	1.5	-1.0	-0.4	1.6	-0.4	1.4	0.5	1.2	1.2	1.2	0.5
Sensitivity / hurt feelings	0.5	0.9	2.0	-0.8	-0.7	-0.1	-1.2	-0.6	-1.2	-0.4	-1.1	-1.4	-1.1	-1.2
Hearing difficulty/problems: Yes	0.5	0.7	2.8	-0.2	-0.5	-0.3	0.1	1.7	0.6	1.6	0.8	0.8	0.8	-0.2
Supplements: Zinc	0.5	0.5	1.8	-0.8	-0.5	-1.0	0.2	0.9	-0.0	-1.1	-0.2	-0.2	-0.2	-1.3
Past tobacco smoking	0.5	1.0	5.1	0.2	2.3	1.5	0.2	-0.2	0.3	0.8	0.4	0.4	0.4	1.4
Forced vital capacity (FVC)	0.5	1.8	5.1	-2.2	-2.1	-1.6	-1.1	-0.3	-0.8	-0.6	-0.8	-0.4	-0.8	-2.1
Medication: Ramipril	0.5	0.6	1.3	0.9	0.6	0.4	1.2	0.1	1.0	-0.3	0.9	0.8	0.9	0.5
Alcohol intake versus 10 years previously	0.5	0.7	2.0	0.8	1.4	1.2	1.4	0.8	0.2	0.1	-0.3	-0.5	-0.3	0.9
Hair/balding pattern: Pattern 3	0.5	0.8	3.9	0.3	-1.1	-1.4	-0.3	2.0	-0.2	-1.1	-0.1	0.1	-0.1	0.6
Noisy workplace	0.5	0.6	1.5	-1.1	1.2	1.0	0.5	-1.2	0.3	1.0	0.0	0.1	0.0	-0.5
Lung cancer (father)	0.5	0.5	1.1	0.6	-0.1	-1.1	0.8	1.0	0.7	-0.6	0.7	0.6	0.7	0.7
Illnesses of mother	0.5	0.7	1.7	-0.4	0.1	-0.1	-0.4	-0.2	-1.0	-0.9	-1.2	-1.3	-1.2	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	4.7	-2.2	-1.5	-1.4	-1.3	-0.5	-1.0	-0.4	-0.9	-0.6	-0.9	-1.8
Birth weight of first child	0.5	0.9	2.1	1.0	-0.9	0.0	0.3	1.4	0.8	1.4	1.0	1.2	1.0	0.7
Pulse wave reflection index	0.5	0.6	2.3	0.1	-1.5	-1.2	-0.8	0.4	0.1	-0.4	0.6	0.8	0.6	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.1	-0.9	-0.3	0.2	-1.5	-0.5	-1.0	-0.3	-0.8	-0.5	-0.8	0.1
Medication: Blood pressure	0.5	0.9	1.7	0.8	0.9	1.0	-0.1	-1.3	-0.8	-1.1	-0.9	-1.1	-0.9	0.8
Leg pain on walking	0.5	0.6	3.1	0.6	0.9	1.2	0.4	0.1	0.3	1.7	0.3	0.1	0.3	0.7
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.3	0.8	0.2	1.1	-0.1	-0.1	0.8	0.8	1.2	0.9	1.2	0.2
Illnesses of father: Heart disease	0.5	0.8	2.0	0.0	0.5	1.4	-1.4	1.2	-0.4	1.0	0.2	0.3	0.2	1.2
Osteoarthritis (self-reported)	0.5	0.7	1.5	1.0	0.7	1.1	1.1	-0.3	0.7	1.1	0.5	0.5	0.5	1.2
High cholesterol (Self-reported)	0.5	1.0	4.0	1.5	1.3	0.8	1.2	0.5	0.4	0.0	0.1	-0.0	0.1	2.0
Medication: Lisinopril	0.5	0.7	3.9	-0.2	2.0	1.5	1.0	0.2	0.4	0.4	0.1	0.1	0.1	0.1
Alcohol drinker status: Never	0.5	0.6	1.3	0.9	-0.3	-0.6	0.8	0.7	1.0	0.1	1.1	1.1	1.1	-0.2
Coronary Artery Disease (CAD)	0.4	0.5	2.7	0.5	0.0	1.2	0.0	1.6	-0.0	0.4	0.0	-0.2	0.0	0.7
Blood White Count	0.4	3.1	9.4	2.0	1.6	-0.6	1.2	3.1	1.3	0.3	1.3	1.7	1.3	2.9
Lung FEV1/FVC ratio	0.4	1.9	3.7	-1.7	0.6	-1.0	-0.7	-1.9	-1.1	-1.8	-1.4	-1.7	-1.4	-1.1
Tanning	0.4	5.0	8.6	-2.2	-2.0	-1.1	-1.9	-2.0	-2.6	-0.9	-2.8	-2.9	-2.8	-2.5
Average weekly spirits intake	0.4	0.5	2.6	0.4	0.6	1.6	-1.1	0.1	-0.3	-0.2	0.2	-0.1	0.2	1.0
Ever used hormone-replacement therapy (HRT)	0.4	0.5	3.6	-0.6	-1.0	-0.4	0.3	-0.6	0.3	-0.1	0.2	0.1	0.2	-1.9
Maternal smoking around birth	0.4	0.5	1.9	0.1	-1.1	-1.2	0.2	-0.8	-0.1	-1.4	-0.2	-0.3	-0.2	-0.5
Qualifications: CSEs or equivalent	0.4	0.6	2.0	-1.3	1.4	0.5	0.4	-0.6	-0.3	-0.1	-0.8	-0.5	-0.8	-0.4
Multivitamins +/- minerals	0.4	0.5	1.2	-0.8	0.6	-0.1	-1.1	-0.6	-0.8	-0.6	-0.6	-1.0	-0.6	-0.8
Number of incorrect matches in round	0.4	0.6	1.2	0.7	-0.2	-0.1	0.8	0.8	1.1	0.5	1.1	1.1	1.1	-0.3
Alcohol usually taken with meals	0.4	0.6	1.7	-0.7	-1.0	-0.7	-0.8	-0.5	-0.5	-1.1	-0.4	-0.5	-0.4	-1.3
Had other major operations	0.4	0.4	1.9	0.6	1.2	0.3	0.6	1.4	0.3	-0.1	0.1	-0.0	0.1	0.8
Heart attack	0.4	0.5	1.6	1.1	0.5	1.0	0.6	0.6	0.4	1.2	0.3	0.1	0.3	0.7
Weight	0.4	1.9	3.3	1.6	1.4	1.3	1.8	-0.5	1.5	1.3	1.3	1.1	1.3	1.4
Trunk fat-free mass	0.4	2.4	6.5	-1.6	-2.5	-2.5	-1.4	0.1	-1.3	-0.8	-1.3	-1.1	-1.3	-1.5
Worrier / anxious feelings	0.4	0.8	2.2	-0.2	0.4	1.0	-0.3	-0.1	-1.0	1.0	-1.2	-1.5	-1.2	-0.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	5.2	-2.3	-1.3	-1.5	-1.1	-0.6	-0.8	-0.5	-0.7	-0.4	-0.7	-1.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.2	-0.2	-1.1	-0.2	-0.6	-0.3	-0.8	0.3	-0.8	-0.8	-0.8	-0.5
Trunk predicted mass	0.4	2.4	6.4	-1.6	-2.5	-2.5	-1.4	0.2	-1.4	-0.7	-1.3	-1.1	-1.3	-1.4
Length of working week for main job	0.4	0.4	1.4	-0.8	-0.2	0.5	-0.8	-1.2	-0.2	0.7	0.1	0.3	0.1	-0.8
Glaucoma (self-reported)	0.4	0.5	2.4	-0.8	0.2	-0.9	0.4	-0.5	0.4	-0.8	0.3	0.1	0.3	-1.5
Forced vital capacity (FVC), Best measure	0.4	1.5	4.7	-1.8	-2.2	-1.4	-1.2	-0.1	-0.9	-0.2	-0.8	-0.3	-0.8	-1.6
Number of children fathered	0.4	0.5	1.7	-0.3	-0.8	-0.4	-0.8	-0.7	-0.8	0.0	-0.6	-0.3	-0.6	1.3
Pulse wave peak to peak time	0.4	0.5	2.4	0.2	1.2	0.4	1.5	0.1	0.7	0.2	0.2	0.2	0.2	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	2.0	-0.2	-0.1	-0.6	0.5	-0.4	-0.5	-1.4	-0.9	-0.8	-0.9	-0.0
Commuting to job workplace: Walk	0.4	0.4	1.6	0.4	-1.2	-0.5	-0.6	0.6	0.1	1.1	0.4	0.4	0.4	0.1
Mineral and other dietary supplements	0.4	0.6	1.7	0.3	0.4	0.6	0.7	0.7	0.7	1.3	0.7	0.9	0.7	0.7
Medication: Bendroflumethiazide	0.4	0.7	1.2	-0.3	0.2	-0.1	-1.0	-1.0	-1.1	-0.7	-1.0	-0.9	-1.0	-0.6
Illnesses of father: High blood pressure	0.4	0.5	3.4	-0.6	-0.1	0.0	-0.2	-1.8	-0.5	-0.1	-0.6	-0.5	-0.6	0.1
Age started oral contraceptive pill	0.4	0.5	2.9	-0.3	-0.0	0.9	-0.2	0.5	0.0	1.1	0.1	-0.1	0.1	-1.7
Diastolic blood pressure, automated reading	0.4	1.2	2.5	1.0	1.6	0.5	0.9	0.5	1.0	1.0	1.0	1.4	1.0	1.5
Supplements: Calcium	0.4	0.4	1.9	-0.4	0.5	0.3	0.7	-0.9	0.4	-0.5	0.2	0.1	0.2	-1.4
Worry (Nagel 2018)	0.3	0.6	1.4	-0.0	-0.2	0.2	-0.5	-0.9	-1.1	0.7	-1.1	-1.2	-1.1	-0.1
Alzheimer’s Disease (including proxy)	0.3	0.5	1.2	-0.3	-1.1	-0.7	-1.1	-0.8	-0.8	-0.1	-0.5	-0.7	-0.5	-0.2
Reaction Time	0.3	0.6	3.1	0.5	-1.1	-1.2	-0.2	1.8	-0.3	-0.5	-0.3	-0.1	-0.3	0.1
Cardiovascular Disease	0.3	0.8	5.2	1.0	1.5	0.1	0.1	0.3	-0.1	-0.8	-0.0	0.3	-0.0	2.3
Systolic blood pressure, automated reading	0.3	0.8	1.8	0.8	1.0	0.6	0.7	0.2	1.0	0.6	1.1	1.3	1.1	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	1.6	1.0	-0.4	-0.3	0.5	0.5	-0.1	0.2	-0.2	-0.4	-0.2	1.3
High blood pressure	0.3	0.8	2.3	-0.2	-0.2	-0.4	-0.8	-1.5	-1.1	-0.6	-1.2	-1.0	-1.2	0.3
Hayfever, allergic rhinitis or eczema	0.3	0.8	3.1	0.8	-1.2	-1.2	-0.2	1.8	0.1	0.7	0.4	0.7	0.4	0.6
Medication: Atenolol	0.3	0.3	1.3	0.5	-0.6	0.2	-0.6	-0.3	-0.5	0.5	-0.4	-0.6	-0.4	1.1
Medication: Levothyroxine sodium	0.3	0.6	3.0	1.1	0.3	0.0	1.7	-0.1	1.0	0.2	0.6	0.4	0.6	0.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	2.0	0.0	-1.4	-0.2	-0.9	1.0	-0.3	0.7	0.0	0.0	0.0	-0.2
Hip circumference	0.3	1.4	4.5	0.9	1.8	2.1	1.5	-0.9	1.0	1.1	0.7	0.3	0.7	0.8
Asthma	0.3	0.5	1.3	-0.0	-1.0	-1.1	-0.6	0.9	-0.5	-0.9	-0.4	-0.3	-0.4	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.6	0.0	-0.8	-0.5	-1.2	0.4	-0.6	-0.9	-0.1	-0.2	-0.1	-0.5
Depression (self-reported)	0.3	0.3	1.1	-0.4	0.4	1.0	-0.3	-0.6	-0.4	0.7	-0.5	-0.6	-0.5	-0.4
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.2	-0.0	-0.8	-0.7	-0.2	-0.9	-0.3	-1.1	-0.3	-0.3	-0.3	-0.6
Angina (self-reported)	0.3	0.4	2.0	0.7	0.2	0.4	1.1	-1.4	0.6	-0.0	0.4	0.2	0.4	0.2
Mean time to correctly identify matches	0.3	0.6	1.5	-0.2	-1.2	-1.2	-0.6	0.8	-0.8	-0.7	-0.8	-0.6	-0.8	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	2.3	0.7	0.3	-0.5	-0.2	0.5	-0.0	-0.4	0.2	0.4	0.2	1.5
Hypertension (Self-reported)	0.3	0.9	2.5	-0.3	-0.2	-0.4	-0.7	-1.6	-1.2	-0.7	-1.3	-1.1	-1.3	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	0.4	0.2	1.3	0.0	-0.7	0.3	0.8	0.4	0.4	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.8	0.3	0.6	-0.3	0.6	0.6	0.8	-0.6	0.9	0.9	0.9	0.3
Mother’s age at death	0.3	0.4	1.1	-0.9	-0.1	-0.5	0.3	0.4	0.4	0.9	0.3	0.6	0.3	-1.0
Average weekly beer plus cider intake	0.3	0.4	1.9	0.0	1.0	0.5	1.4	-0.5	0.7	0.5	0.3	-0.0	0.3	-0.6
Irritability	0.3	0.4	1.0	0.4	0.3	0.2	1.0	-0.6	0.9	0.8	0.7	0.7	0.7	-0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	1.1	0.5	1.0	0.5	0.6	0.2	1.0	0.2	-0.0	0.2	0.8
Depression (Nagel 2018)	0.2	0.2	0.9	0.4	-0.1	-0.4	0.4	0.7	0.2	0.9	0.2	0.4	0.2	0.5
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.2	-0.4	-0.3	-0.5	-0.1	-0.9	0.4	-1.0	-0.9	-1.0	-0.0
Schizophrenia vs Biploar Disorder	0.2	0.3	2.0	0.0	0.0	1.4	0.0	-0.9	0.0	0.1	0.5	0.4	0.5	-0.0
Alzheimer’s Disease (in mother)	0.2	0.3	1.1	0.3	-0.6	0.5	-0.3	-1.0	-0.3	1.0	-0.2	-0.5	-0.2	0.1
Ulcerative Colitis (UC)	0.2	0.4	2.2	-0.4	0.3	0.6	0.6	-1.1	0.1	0.1	-0.2	-0.3	-0.2	-1.5
Blood Red Count	0.2	2.1	15.3	-0.1	-1.7	-2.0	-0.3	3.9	0.1	0.1	0.2	0.1	0.2	-0.8
Neuroticism	0.2	0.5	1.4	0.2	-0.0	-0.3	0.1	0.5	-0.8	0.3	-1.1	-1.2	-1.1	-0.3
Chronotype (morning person)	0.2	0.4	2.2	-0.4	0.1	0.7	-1.5	0.8	-0.7	0.1	-0.2	-0.2	-0.2	0.5
Hair Pigment	0.2	4.6	8.9	2.1	2.0	1.3	2.0	3.0	2.2	0.8	2.3	2.0	2.3	2.6
Frequency of depressed mood in last 2 weeks	0.2	0.2	0.8	0.8	-0.8	-0.4	0.4	0.3	0.1	0.3	0.0	0.1	0.0	0.9
Fed-up feelings	0.2	0.3	1.0	-0.3	-0.6	-1.0	0.2	0.1	-0.4	0.1	-0.7	-0.7	-0.7	-0.5
Neuroticism score	0.2	0.3	0.8	0.6	0.1	0.0	0.3	0.8	-0.5	0.6	-0.7	-0.9	-0.7	0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	1.4	1.2	0.3	0.5	0.8	0.5	0.5	-0.2	0.4	0.1	0.4	0.6
Tense / ‘highly strung’	0.2	0.4	1.3	0.7	0.6	0.2	0.8	0.9	0.5	0.4	0.3	0.5	0.3	1.1
Peak expiratory flow (PEF)	0.2	0.4	1.1	-0.8	0.1	-1.1	0.3	-0.1	0.7	-0.2	0.7	0.7	0.7	-0.8
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.5	-0.3	-0.5	-0.4	-0.2	-0.6	-0.5	-0.5	-0.6	-0.7	-0.6	-0.6
Comparative body size at age 10	0.2	0.5	1.2	0.5	0.5	0.1	0.2	0.4	0.8	-0.4	1.0	1.1	1.0	0.7
Emphysema/chronic bronchitis	0.2	0.2	0.6	-0.4	-0.8	-0.6	0.5	-0.6	-0.1	0.4	-0.5	-0.4	-0.5	-0.3
Medication: Ibuprofen	0.2	0.2	0.6	0.7	-0.7	-0.4	-0.8	0.2	-0.2	-0.5	0.2	0.2	0.2	0.2
Knee pain experienced in last month	0.2	0.3	2.1	0.1	0.4	-0.1	0.9	-1.4	0.6	-0.2	0.4	-0.0	0.4	-0.1
Whole body fat-free mass	0.2	0.9	3.5	-0.9	-1.7	-1.9	-0.6	0.2	-0.6	-0.5	-0.7	-0.6	-0.7	-0.7
Average weekly red wine intake	0.2	0.4	1.5	-0.5	-0.4	-0.5	-1.2	0.0	-0.9	0.0	-0.6	-0.4	-0.6	-0.0
Medication for cholesterol	0.2	0.3	2.5	-0.3	-0.4	0.0	-0.5	0.4	-0.1	-0.2	0.1	-0.1	0.1	-1.6
Asthma (self-reported)	0.2	0.4	1.1	0.0	-0.9	-1.0	-0.4	0.5	-0.5	-0.8	-0.4	-0.3	-0.4	-0.9
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.8	0.3	0.1	0.9	-0.7	-0.8	-0.5	0.1	-0.3	-0.5	-0.3	0.2
Medication: Blood pressure	0.2	0.4	1.3	0.0	0.8	0.9	0.6	-0.5	0.3	1.1	0.1	0.4	0.1	0.9
Medication: Atorvastatin	0.2	0.3	0.8	0.1	-0.5	-0.2	0.1	-0.2	-0.6	-0.1	-0.9	-0.8	-0.9	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.5	-0.3	0.1	0.1	0.6	1.2	1.0	0.2	1.1	0.9	1.1	-0.8
Pain experienced in last month	0.2	0.3	2.0	-0.2	0.2	0.4	-0.4	0.8	-0.2	1.4	-0.1	0.2	-0.1	0.0
Systolic Blood Pressure	0.1	0.7	2.5	-0.4	-1.4	-1.0	-1.6	0.5	-0.8	-0.7	-0.3	0.2	-0.3	0.4
Respiratory disease	0.1	0.3	1.4	0.6	-1.2	-0.8	0.2	0.9	0.2	0.3	0.2	0.4	0.2	-0.2
Hearing difficulty/problems with background noise	0.1	0.2	0.8	-0.1	0.2	0.5	0.6	-0.3	0.4	0.7	0.3	0.0	0.3	-0.9
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	0.2	-0.1	-0.4	0.1	-0.6	0.2	-0.1	0.2	0.6	0.2	0.6
Allergy	0.1	0.3	1.3	-0.5	1.0	1.1	-0.0	-1.0	0.1	-0.0	0.0	-0.3	0.0	0.1
Time employed in main current job	0.1	0.1	0.3	-0.3	0.5	0.0	0.0	0.3	0.2	-0.5	0.2	-0.0	0.2	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.4	0.2	-0.6	-0.3	0.5	-0.2	-0.1	0.3	-0.4	-0.3	-0.4	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.0	-0.0	1.0	0.6	0.5	-0.7	0.2	0.5	-0.0	-0.2	-0.0	-0.3
Loud music exposure frequency	0.1	0.2	0.7	0.7	0.8	0.3	0.3	0.1	-0.1	-0.2	-0.2	-0.4	-0.2	0.0
Headache pain in last month	0.1	0.2	0.5	0.3	-0.6	-0.0	-0.4	0.2	0.3	-0.7	0.7	0.5	0.7	-0.4
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.9	0.5	-0.4	0.1	0.2	-0.2	-0.0	1.0	-0.1	0.1	-0.1	0.2
Birth weight	0.1	0.1	0.4	-0.1	0.6	-0.1	0.7	-0.6	0.4	0.0	0.2	0.0	0.2	0.4
Arm fat-free mass (right)	0.1	0.4	1.1	0.5	0.1	-0.5	1.1	0.0	0.9	0.1	0.8	0.7	0.8	0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	0.2	-0.3	-0.0	-0.4	-0.5	0.2	0.3	0.4	0.3	0.4	-0.2
Arm predicted mass (right)	0.1	0.5	1.1	0.6	0.3	-0.2	1.1	0.2	1.1	0.5	0.9	0.9	0.9	0.5
Illnesses of siblings: Diabetes	0.1	0.1	0.3	0.0	0.5	0.3	-0.4	0.3	0.0	-0.2	0.2	0.2	0.2	-0.3
Leg fat-free mass (right)	0.1	0.4	1.9	-0.3	-1.3	-1.4	-0.0	0.2	-0.2	-0.4	-0.3	-0.2	-0.3	-0.2
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.4	0.3	-0.3	-0.6	0.4	0.4	-0.2	-0.4	-0.5	-0.4	-0.5	-0.0
Back pain experienced in last month	0.1	0.1	0.5	0.3	0.2	0.5	0.2	0.7	0.0	-0.0	0.0	-0.2	0.0	-0.0
Osteoporosis (self-reported)	0.1	0.1	0.7	0.1	-0.6	0.2	-0.1	-0.8	-0.1	-0.2	-0.0	-0.1	-0.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.7	0.3	-0.0	0.6	0.2	0.2	0.4	0.9	0.4	0.7	0.4	0.6
Whole body water mass	0.1	0.7	2.8	-0.8	-1.5	-1.7	-0.5	0.2	-0.4	-0.3	-0.5	-0.4	-0.5	-0.7
Leg predicted mass (right)	0.1	0.4	2.0	-0.3	-1.4	-1.4	-0.0	0.1	-0.2	-0.4	-0.3	-0.2	-0.3	-0.2
Arm fat-free mass (left)	0.1	0.3	0.7	0.6	-0.0	-0.5	0.8	0.4	0.8	0.3	0.7	0.6	0.7	0.4
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.8	0.1	0.2	0.6	-0.2	-0.3	-0.0	0.4	0.1	0.3	0.1	0.9
Heart disease (siblings)	0.1	0.1	0.5	0.4	0.0	0.1	-0.2	0.4	-0.2	-0.6	-0.1	-0.2	-0.1	0.7
Arm predicted mass (left)	0.1	0.3	0.9	0.4	0.1	-0.4	0.9	0.3	0.8	0.4	0.7	0.7	0.7	0.3
Breast Cancer	0.0	0.1	0.3	-0.4	-0.3	-0.2	-0.2	-0.1	-0.1	0.5	-0.1	0.0	-0.1	-0.6
Bipolar Disorder (2011)	0.0	0.0	0.1	0.0	0.0	-0.0	0.0	-0.3	0.0	0.2	0.0	-0.1	0.0	-0.2
Leg fat-free mass (left)	0.0	0.2	1.2	-0.1	-0.9	-1.1	0.2	0.4	-0.0	-0.2	-0.1	-0.1	-0.1	0.1
Leg predicted mass (left)	0.0	0.2	1.2	-0.1	-1.0	-1.1	0.2	0.4	0.0	-0.2	-0.1	-0.1	-0.1	0.0
Mouth/teeth dental problems	0.0	0.1	0.2	-0.1	-0.3	-0.1	0.2	0.4	0.1	0.4	0.0	0.3	0.0	-0.1
Basal metabolic rate	0.0	0.2	0.9	-0.1	-0.9	-1.0	0.1	0.1	0.0	0.0	-0.0	-0.0	-0.0	-0.1

Hub : Genes

C17orf103

Models

Trait associations