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Traits
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Traits
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Impedance of arm (left)
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chr2:182,305,254-184,341,553
Best TWAS P=1.54e-09 · Best GWAS P=8.31e-13 conditioned to 1.06e-05
182.5M
183M
183.5M
184M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Brain Hypothalamus
PDE1A
0.24
-0.01
enet
21
-0.01
7.6e-01
-5.0
-6.0
1.5e-09
-0.60
0.07
0.31
TRUE
5
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
PDE1A
0.05
0.04
blup
206
0.04
5.0e-05
4.9
-5.6
1.8e-08
-0.42
0.64
0.03
FALSE
4
The Cancer Genome Atlas
Breast Invasive Carcinoma
PDE1A
0.03
0.01
blup
209
0.02
1.3e-05
1.5
-5.3
1.2e-07
-0.37
0.48
0.02
FALSE
3
ROSMAP
Brain Pre-frontal Cortex
PDE1A
0.11
0.03
bslmm
526
0.06
3.2e-08
7.2
-5.3
1.4e-07
-0.62
0.00
1.00
FALSE
1
CommonMind
Brain Pre-frontal Cortex
DNAJC10
0.11
0.04
enet
19
0.06
2.1e-07
3.7
-5.2
1.9e-07
-0.25
0.99
0.00
FALSE