Best TWAS P=3.15e-09 · Best GWAS P=2.72e-10 conditioned to 0.00794
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR75 | 0.05 | 0.04 | lasso | 2 | 0.03 | 0.0012 | -5.6 | 5.7 | 1.1e-08 | -0.68 | 0.12 | 0.58 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | WDR75 | 0.16 | 0.00 | lasso | 9 | 0.00 | 0.2640 | -5.8 | 5.4 | 7.3e-08 | -0.66 | 0.04 | 0.21 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | WDR75 | 0.05 | 0.04 | lasso | 4 | 0.03 | 0.0012 | -5.8 | 5.9 | 4.3e-09 | -0.63 | 0.07 | 0.90 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | COL5A2 | 0.04 | 0.00 | blup | 79 | 0.02 | 0.0059 | -6.3 | 5.9 | 3.2e-09 | -0.79 | 0.02 | 0.76 | TRUE |