[Hub]/) : Traits : Impedance of arm (left) :

chr3:41,948,665-43,544,836

Best TWAS P=2.12e-14 · Best GWAS P=2.01e-14 conditioned to 0.0832

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex HHATL 0.25 0.22 lasso 8 0.27 5.5e-33 -7.7 -7.6 2.1e-14 0.90 0.00 1.00 TRUE
2 GTEx Adipose Subcutaneous RP4-613B23.1 0.07 0.02 lasso 2 0.02 9.0e-03 -5.8 -5.6 1.7e-08 0.53 0.15 0.27 FALSE
3 GTEx Artery Aorta CCDC13 0.19 0.13 enet 29 0.14 5.0e-08 -6.7 -5.2 2.2e-07 0.47 0.43 0.55 FALSE
4 GTEx Brain Cortex HIGD1A 0.28 0.02 enet 36 0.12 3.6e-04 -7.5 5.6 2.3e-08 -0.60 0.01 0.92 FALSE
5 GTEx Muscle Skeletal CCDC13 0.08 0.00 enet 5 0.00 5.8e-01 -6.6 -6.4 1.5e-10 0.65 0.06 0.48 FALSE
6 GTEx Thyroid HIGD1A 0.10 0.09 lasso 5 0.07 2.5e-06 -4.9 5.1 3.0e-07 -0.86 0.01 0.98 FALSE
7 ROSMAP Brain Pre-frontal Cortex HHATL 0.21 0.15 bslmm 465 0.18 1.3e-22 3.5 -6.3 2.3e-10 0.75 0.72 0.28 FALSE
8 ROSMAP Brain Pre-frontal Cortex HIGD1A 0.40 0.38 enet 35 0.41 3.1e-56 -4.9 5.3 9.8e-08 -0.82 1.00 0.00 FALSE
9 The Cancer Genome Atlas Glioblastoma Multiforme HHATL 0.18 0.12 enet 7 0.21 5.2e-07 3.5 -6.3 3.0e-10 0.74 0.03 0.91 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma HHATL 0.09 0.05 enet 10 0.10 7.4e-12 -7.5 -6.8 1.3e-11 0.78 0.01 0.99 FALSE